Abstract:
:Coefficient of kinetic friction (μ) between rabbit visceral and parietal pleura, sliding in vitro at physiological velocities and load, increases markedly after blotting mesothelial surface with filter paper; this increase is only partially reduced by wetting blotted mesothelium with Ringer solution. Given that mesothelial surface is covered by a thick coat with sialomucin and hyaluronan, we tested whether addition of sialomucin or hyaluronan solution after blotting lowers μ more than Ringer alone. Actually, these macromolecules lowered μ more than Ringer, so that μ was no longer significantly higher than its preblotting value. Moreover, Ringer addition, after washout of macromolecule solution, increased μ, in line with their dilution. These findings indicate that mesothelial blotting removes part of these molecules from the coat covering mesothelial surface, and their relevance for pleural lubrication. Transmission electron micrographs of pleural specimens after mesothelial blotting showed that microvilli were partially or largely removed from mesothelium, consistent with a substantial loss of macromolecules normally entrapped among them.
journal_name
Respir Physiol Neurobioljournal_title
Respiratory physiology & neurobiologyauthors
Bodega F,Pecchiari M,Sironi C,Porta C,Arnaboldi F,Barajon I,Agostoni Edoi
10.1016/j.resp.2011.10.006subject
Has Abstractpub_date
2012-01-15 00:00:00pages
34-9issue
1eissn
1569-9048issn
1878-1519pii
S1569-9048(11)00356-9journal_volume
180pub_type
杂志文章abstract::We compared by non-invasive technique the adaptive response of alveolar capillary network to edemagenic conditions (exercise and high altitude [HA, PIO2 107mmHg] in subjects with different resting sea level (SL) capillary blood volume (normalized to alveolar volume, Vc/Va): Group 1 (N=10, Vc/Va=16.1±6.8ml/L- mean±SD) ...
journal_title:Respiratory physiology & neurobiology
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journal_title:Respiratory physiology & neurobiology
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journal_title:Respiratory physiology & neurobiology
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journal_title:Respiratory physiology & neurobiology
pub_type: 杂志文章,评审
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journal_title:Respiratory physiology & neurobiology
pub_type: 杂志文章,评审
doi:10.1016/j.resp.2017.01.013
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journal_title:Respiratory physiology & neurobiology
pub_type: 社论
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journal_title:Respiratory physiology & neurobiology
pub_type: 杂志文章,评审
doi:10.1016/j.resp.2005.05.004
更新日期:2005-11-15 00:00:00
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journal_title:Respiratory physiology & neurobiology
pub_type: 杂志文章
doi:10.1016/j.resp.2017.09.005
更新日期:2018-01-01 00:00:00
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journal_title:Respiratory physiology & neurobiology
pub_type: 杂志文章
doi:10.1016/j.resp.2005.09.005
更新日期:2006-08-01 00:00:00
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journal_title:Respiratory physiology & neurobiology
pub_type: 杂志文章
doi:10.1016/j.resp.2009.02.014
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journal_title:Respiratory physiology & neurobiology
pub_type: 杂志文章
doi:10.1016/j.resp.2009.08.010
更新日期:2009-10-31 00:00:00
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journal_title:Respiratory physiology & neurobiology
pub_type: 杂志文章,评审
doi:10.1016/j.resp.2010.08.009
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journal_title:Respiratory physiology & neurobiology
pub_type: 杂志文章,评审
doi:10.1016/j.resp.2010.04.024
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journal_title:Respiratory physiology & neurobiology
pub_type: 杂志文章
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journal_title:Respiratory physiology & neurobiology
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journal_title:Respiratory physiology & neurobiology
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journal_title:Respiratory physiology & neurobiology
pub_type: 杂志文章
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更新日期:2019-04-01 00:00:00
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journal_title:Respiratory physiology & neurobiology
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journal_title:Respiratory physiology & neurobiology
pub_type: 杂志文章
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journal_title:Respiratory physiology & neurobiology
pub_type: 杂志文章
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journal_title:Respiratory physiology & neurobiology
pub_type: 杂志文章
doi:10.1016/j.resp.2015.09.011
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