Genetics and function of neocortical GABAergic interneurons in neurodevelopmental disorders.

abstract：:Neuropathic pain increases the risk of cardiovascular diseases including hypertension with the characteristic of sympathetic overactivity. The enhanced tonically active glutamatergic input to the rostral ventrolateral medulla (RVLM) contributes to sympathetic overactivity and blood pressure (BP) in cardiovascular dise...

journal_title：Neural plasticity

authors： Wang W,Zou Z,Tan X,Zhang RW,Ren CZ,Yao XY,Li CB,Wang WZ,Shi XY

更新日期：2017-01-01 00:00:00

abstract：:Proper functioning of the visual system depends on maturation of both excitatory and inhibitory synapses within the visual cortex. Considering that perisomatic inhibition is one of the key factors that control the critical period in visual cortex, it is pertinent to understand its regulation by visual experience. To d...

journal_title：Neural plasticity

authors： Kreczko A,Goel A,Song L,Lee HK

更新日期：2009-01-01 00:00:00

abstract：:Although many studies have investigated the functions of histidine triad nucleotide-binding protein 1 (HINT1), its roles in neurobiological processes remain to be fully elucidated. As a member of the histidine triad (HIT) enzyme superfamily, HINT1 is distributed in almost every organ and has both enzymatic and nonenzy...

journal_title：Neural plasticity

authors： Liu P,Liu Z,Wang J,Ma X,Dang Y

更新日期：2017-01-01 00:00:00

abstract：:To decipher the genotype-phenotype correlation of auditory neuropathy (AN) caused by AIFM1 variations, as well as the phenotype progression of these patients, exploring the potential molecular pathogenic mechanism of AN. A total of 36 families of individuals with AN (50 cases) with AIFM1 variations were recruited and ...

journal_title：Neural plasticity

authors： Wang H,Bing D,Li J,Xie L,Xiong F,Lan L,Wang D,Guan J,Wang Q

更新日期：2020-07-01 00:00:00

abstract：:Matricellular proteins are secreted, nonstructural proteins that regulate the extracellular matrix (ECM) and interactions between cells through modulation of growth factor signaling, cell adhesion, migration, and proliferation. Despite being well described in the context of nonneuronal tissues, recent studies have rev...

journal_title：Neural plasticity

authors： Jones EV,Bouvier DS

更新日期：2014-01-01 00:00:00

abstract：:Several studies have associated reduced expression of synaptosomal-associated protein of 25 kDa (SNAP-25) with schizophrenia, yet little is known about its role in the illness. In this paper, a forebrain glutamatergic neuron-specific SNAP-25 knockout mouse model was constructed and studied to explore the possible path...

journal_title：Neural plasticity

authors： Yang H,Zhang M,Shi J,Zhou Y,Wan Z,Wang Y,Wan Y,Li J,Wang Z,Fei J

更新日期：2017-01-01 00:00:00

abstract：:Following central motor lesions, two forms of adaptation can be observed which lead to improved mobility: (1) the development of spastic muscle tone, and (2) the activation of spinal locomotor centers induced by specific treadmill training. Tension development during spastic gait is different from that during normal g...

journal_title：Neural plasticity

authors： Dietz V

更新日期：2001-01-01 00:00:00

abstract：:Action observation (AO) allows access to a network that processes visuomotor and sensorimotor inputs and is believed to be involved in observational learning of motor skills. We conducted three consecutive experiments to examine the boosting effect of AO on the motor outcome of the untrained hand by either mirror visu...

journal_title：Neural plasticity

authors： Bähr F,Ritter A,Seidel G,Puta C,Gabriel HHW,Hamzei F

更新日期：2018-04-10 00:00:00

abstract：:The endocannabinoids N-arachidonoylethanolamide (or anandamide, AEA) and 2-arachidonoylglycerol (2-AG) belong to the larger groups of N-acylethanolamines (NAEs) and monoacylglycerol (MAG) lipid classes, respectively. They are biologically active lipid molecules that activate G-protein-coupled cannabinoid receptors fou...

journal_title：Neural plasticity

authors： Keereetaweep J,Chapman KD

更新日期：2016-01-01 00:00:00

abstract：Background:Sudden sensorineural hearing loss (SSNHL) is an otologic emergency and could lead to social difficulties and mental disorders in some patients. Although many studies have analyzed altered brain function in populations with hearing loss, little information is available about patients with idiopathic SSNHL. Th...

journal_title：Neural plasticity

authors： Chen J,Hu B,Qin P,Gao W,Liu C,Zi D,Ding X,Yu Y,Cui G,Lu L

更新日期：2020-09-22 00:00:00

abstract：:One major goal in Neuroscience is the development of strategies promoting neural plasticity in the adult central nervous system, when functional recovery from brain disease and injury is limited. New evidence has underscored a pivotal role for cortical inhibitory circuitries in regulating plasticity both during develo...

journal_title：Neural plasticity

authors： Baroncelli L,Braschi C,Spolidoro M,Begenisic T,Maffei L,Sale A

更新日期：2011-01-01 00:00:00

abstract：:Homeostatic synaptic plasticity is a negative-feedback response employed to compensate for functional disturbances in the nervous system. Typically, synaptic activity is strengthened when neuronal firing is chronically suppressed or weakened when neuronal activity is chronically elevated. At both the whole cell and en...

journal_title：Neural plasticity

authors： Wang G,Gilbert J,Man HY

更新日期：2012-01-01 00:00:00

abstract：:Elevated brain activation, or hyperexcitability, induces cognitive impairment and confers an increased risk of Alzheimer's disease (AD). Blocking the overexcitation of the neural network may be a promising new strategy to prevent, halt, and even reverse this condition. Physical exercise has been shown to be an effecti...

journal_title：Neural plasticity

authors： Tan YX,Liu GC,Chen HL,Lu MN,Chen B,Hu T,Zhang L,Mao R,Li S,Mei R,Wang XY,Xiyang YB

更新日期：2020-03-18 00:00:00

abstract：:The aim of this study was to investigate the effect of subdiaphragmatic vagotomy on insulin sensitivity, secretion, and degradation in metabolic programmed mice, induced by a low-protein diet early in life, followed by exposure to a high-fat diet in adulthood. Weaned 30-day-old C57Bl/6 mice were submitted to a low-pro...

journal_title：Neural plasticity

authors： Lubaczeuski C,Gonçalves LM,Vettorazzi JF,Kurauti MA,Santos-Silva JC,Bonfleur ML,Boschero AC,Costa-Júnior JM,Carneiro EM

更新日期：2017-01-01 00:00:00

abstract：:The objective of this study was to assess the evolution of diffusion-weighted imaging (DWI) and diffusion-tensor imaging (DTI) over the first month of life in asphyxiated newborns treated with hypothermia and to compare it with that of healthy newborns. Asphyxiated newborns treated with hypothermia were enrolled prosp...

journal_title：Neural plasticity

authors： Kwan S,Boudes E,Benseler A,Gilbert G,Saint-Martin C,Shevell M,Wintermark P

更新日期：2015-01-01 00:00:00

abstract：:Stress can cause a variety of central nervous system disorders, which are critically mediated by the γ-aminobutyric acid (GABA) system in various brain structures. GABAergic neurons have different subsets, some of which coexpress certain neuropeptides that can be found in the digestive system. Accumulating evidence de...

journal_title：Neural plasticity

authors： Hou X,Rong C,Wang F,Liu X,Sun Y,Zhang HT

更新日期：2020-08-01 00:00:00

abstract：:Cyclothiazide (CTZ) has been reported to simultaneously enhance glutamate receptor excitation and inhibit GABAA receptor inhibition, and in turn it evokes epileptiform activities in hippocampal neurons. It has also been shown to acutely induce epileptic seizure behavior in freely moving rats. However, whether CTZ indu...

journal_title：Neural plasticity

authors： Kong S,Cheng Z,Liu J,Wang Y

更新日期：2014-01-01 00:00:00

abstract：:Cholinergic mechanism is involved in motor behavior. In songbirds, the robust nucleus of the arcopallium (RA) is a song premotor nucleus in the pallium and receives cholinergic inputs from the basal forebrain. The activity of projection neurons in RA determines song motor behavior. Although many evidences suggest that...

journal_title：Neural plasticity

authors： Meng W,Wang SH,Li DF

更新日期：2016-01-01 00:00:00

abstract：Background:Parkinson's disease (PD) patients experience cognitive impairment which has been related to reduced quality of life and functional disability. These symptoms usually progress until dementia occurs. Some studies have been published assessing the efficacy of cognitive treatments on improving cognition, functio...

journal_title：Neural plasticity

authors： Díez-Cirarda M,Ibarretxe-Bilbao N,Peña J,Ojeda N

更新日期：2018-05-06 00:00:00

abstract：:The aim of the present study was to assess the role of action observation treatment (AOT) in the rehabilitation of upper limb motor functions in children with cerebral palsy. We carried out a two-group, parallel randomized controlled trial. Eighteen children (aged 5-11 yr) entered the study: 11 were treated children, ...

journal_title：Neural plasticity

authors： Buccino G,Molinaro A,Ambrosi C,Arisi D,Mascaro L,Pinardi C,Rossi A,Gasparotti R,Fazzi E,Galli J

更新日期：2018-07-04 00:00:00

abstract：Background:Despite intensive rehabilitation efforts, most stroke survivors have persistent functional disability of the paretic arm and hand. These motor impairments may be due in part to maladaptive changes in structural and functional connections between brain regions. The following early stage clinical trial study p...

journal_title：Neural plasticity

authors： Borich MR,Wolf SL,Tan AQ,Palmer JA

更新日期：2018-03-12 00:00:00

abstract：:Functional and morphological studies in children affected by Attention Deficit Hyperactivity Disorder (ADHD) suggest a prefrontal cortex (PFc) dysfunction. This cortical region is regulated by subcortical systems including noradrenergic (NEergic), dopaminergic (DAergic), cholinergic, serotonergic, and histaminergic pa...

journal_title：Neural plasticity

authors： Viggiano D,Ruocco LA,Arcieri S,Sadile AG

更新日期：2004-01-01 00:00:00

abstract：:Hyperpolarization-activated, cyclic nucleotide-gated nonselective (HCN) channels modulate both membrane potential and resistance and play a significant role in synaptic plasticity. We compared the influence of HCN channels on long-term depression (LTD) at the medial perforant path-granule cell synapse in early postnat...

journal_title：Neural plasticity

authors： Guli X,Tokay T,Rohde M,Bender RA,Köhling R,Kirschstein T

更新日期：2012-01-01 00:00:00

abstract：:Recently, transcranial alternating current stimulation (tACS) has emerged as a tool to enhance human cognitive processes. Here, we provide a brief summary of the rationale behind tACS-induced effects on task-relevant brain oscillations and associated cognitive functions and review previous studies in young subjects th...

journal_title：Neural plasticity

authors： Antonenko D,Faxel M,Grittner U,Lavidor M,Flöel A

更新日期：2016-01-01 00:00:00

abstract：:Little is known about prenatal and perinatal brain injury resulting in subsequent clumsy behavior in children. One candidate motor system is the pyramidal tract. The tract traverses the entire central nervous system and, through direct and indirect connections to the brainstem and spinal cord sensory and motor nuclei,...

journal_title：Neural plasticity

authors： Whishaw IQ,Piecharka DM,Drever FR

更新日期：2003-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is the most common form of dementia in the elderly; important risk factors are old age and inheritance of the apolipoprotein E4 (APOE4) allele. Changes in amyloid precursor protein (APP) binding, trafficking, and sorting may be important AD causative factors. Secretase-mediated APP cleavage pr...

journal_title：Neural plasticity

authors： Zollo A,Allen Z,Rasmussen HF,Iannuzzi F,Shi Y,Larsen A,Maier TJ,Matrone C

更新日期：2017-01-01 00:00:00

abstract：:Dopamine (DA) modulates glutamatergic synaptic transmission and its plasticity in the striatum; however it is not well known how DA modulates long-term plasticity of striatal GABAergic inhibitory synapses. This work focused on the analysis of both dopaminergic modulation of inhibitory synapses and the synaptic plastic...

journal_title：Neural plasticity

authors： Nieto Mendoza E,Hernández Echeagaray E

更新日期：2015-01-01 00:00:00

abstract：:Emotionally arousing events are typically better remembered than mundane ones, in part because emotionally relevant aspects of our environment are prioritized in attention. Such biased attentional tuning is itself the result of associative processes through which we learn affective and motivational relevance of cues. ...

journal_title：Neural plasticity

authors： Ehlers MR,Todd RM

更新日期：2017-01-01 00:00:00

abstract：:Transcranial Direct Current Stimulation (tDCS) is an emerging tool to improve upper limb motor functions after stroke acquired in adulthood; however, there is a paucity of reports on its efficacy for upper limb motor rehabilitation in congenital or early-acquired stroke. In this pilot study we have explored, for the f...

journal_title：Neural plasticity

authors： Inguaggiato E,Bolognini N,Fiori S,Cioni G

更新日期：2019-01-15 00:00:00

abstract：:Patients suffering from chronic disorders of consciousness (DOC) are characterized by profound unawareness and an impairment of large-scale cortical and subcortical connectivity. In this study, we applied an electrophysiological approach aimed at identifying the residual audiomotor connectivity patterns that are thoug...

journal_title：Neural plasticity

authors： Naro A,Leo A,Cannavò A,Buda A,Bruno R,Salviera C,Bramanti P,Calabrò RS

更新日期：2015-01-01 00:00:00