Resistance to Yersinia pestis infection decreases with age in B10.T(6R) mice.

abstract：:The effects of treatment with live or inactivated Shope fibroma virus on host cell deoxyribonucleic acid (DNA) synthesis were determined. The incorporation of (3)H-thymidine into nuclear DNA was suppressed by both active and inactivated virus, although live virus was more effective. During the early phase of infection...

journal_title：Infection and immunity

authors： Chan JC,Hodes ME

更新日期：1973-04-01 00:00:00

abstract：:The guinea pig migration inhibition technique, an accepted in vitro correlate of delayed hypersensitivity, has been adapted to a murine system. Peritoneal exudate cells from CF-1 mice vaccinated with viable cells of the H37Ra strain of Mycobacterium tuberculosis were inhibited in vitro by purified protein derivative (...

journal_title：Infection and immunity

authors： Neiburger RG,Youmans GP

更新日期：1973-02-01 00:00:00

abstract：:Production of the Kanagawa hemolysin by patient strains of Vibrio parahaemolyticus was found to respond to the pH rather than to the type of carbohydrate present in the growth medium. Regardless of the carbohydrate present, hemolysin production in peptone broth cultures occurred only when the pH was between 6.5 and 5....

journal_title：Infection and immunity

authors： Cherwonogrodzky JW,Clark AG

更新日期：1981-10-01 00:00:00

abstract：:Invasive aspergillosis is a major threat for patients suffering from chronic granulomatous disease (CGD). Although Aspergillus fumigatus is the most commonly encountered Aspergillus species, the presence of A. nidulans appears to be disproportionately high in CGD patients. The purpose of this study was to investigate ...

journal_title：Infection and immunity

authors： Henriet SS,Hermans PW,Verweij PE,Simonetti E,Holland SM,Sugui JA,Kwon-Chung KJ,Warris A

更新日期：2011-02-01 00:00:00

abstract：:Serum antibody responses to toxic shock syndrome (TSS) toxin 1 (TSST-1) and staphylococcal enterotoxins A, B, and C were determined by western blot (immunoblot) analysis of acute- and convalescent-phase paired sera from 18 TSS- and 31 non-TSS-associated Staphylococcus aureus infections. Compared with non-TSS cases, se...

journal_title：Infection and immunity

authors： Whiting JL,Rosten PM,Chow AW

更新日期：1989-01-01 00:00:00

abstract：:Peptic ulcer disease (PUD) occurs after a long-term Helicobacter pylori infection. However, the disease can develop earlier, and rare cases have been observed in children, suggesting that these H. pylori strains may be more virulent. We used suppressive subtractive hybridization for comparative genomics between H. pyl...

journal_title：Infection and immunity

authors： Oleastro M,Monteiro L,Lehours P,Mégraud F,Ménard A

更新日期：2006-07-01 00:00:00

abstract：:Peptidoglycans of Leptotrichia buccalis ATCC 14201 and ATCC 19616 were isolated by extraction with sodium dodecyl sulfate and subsequent digestion of the sodium dodecyl sulfate-insoluble residue with proteases and alpha-amylase. Cell wall fractions obtained by sodium dodecyl sulfate extraction and protease digestion w...

journal_title：Infection and immunity

authors： Fukuhara H,Umemoto T,Sagawa H,Kato K,Kotani S

更新日期：1983-01-01 00:00:00

abstract：:Legionella pneumophila is ingested by both human macrophages and amoebae, and it multiplies within similar endocytic compartments in both eukaryotic species. Inhibitors of eukaryotic protein synthesis, such as cycloheximide and emetine, had no effect on the uptake of L. pneumophila by macrophages but completely abolis...

journal_title：Infection and immunity

authors： abu Kwaik Y,Fields BS,Engleberg NC

更新日期：1994-05-01 00:00:00

abstract：:To evaluate the roles of the infectious agent and the host in the pathogensis of Salmonella-associated arthritis (SAA), 1O(3) to 10(6) heat-killed Salmonella enteritidis were injected directly into involved carpal joints in normal and actively immunized rats and in hosts adoptively immunized by the intravenous transfe...

journal_title：Infection and immunity

authors： Volkman A,Collins FM

更新日期：1976-04-01 00:00:00

abstract：:Escherichia coli heat-stable enterotoxin (ST) appears to cause intestinal fluid secretion by activating intestinal particulate guanylate cyclase. Recent studies suggest that chlorpromazine and quinacrine reduce the intestinal secretory response to ST and activation of guanylate cyclase by ST. We have examined the effe...

journal_title：Infection and immunity

authors： Greenberg RN,Murad F,Guerrant RL

更新日期：1982-02-01 00:00:00

abstract：:Cytolethal distending toxins (CDT) constitute an emerging heterogeneous family of bacterial toxins whose common biological property is to inhibit the proliferation of cells in culture by blocking their cycle at G2/M phase. In this study, we investigated the molecular mechanisms underlying the block caused by CDT from ...

journal_title：Infection and immunity

authors： Comayras C,Tasca C,Pérès SY,Ducommun B,Oswald E,De Rycke J

更新日期：1997-12-01 00:00:00

abstract：:Strains of Cryptococcus neoformans vary in resistance to phagocytosis in vitro. The binding of isolated capsular polysaccharide (CPS) to a capsule-free mutant of C. neoformans confers resistance to phagocytosis. The importance of capsule composition to differences among strains in susceptibility to phagocytosis was ev...

journal_title：Infection and immunity

authors： Small JM,Mitchell TG

更新日期：1989-12-01 00:00:00

abstract：:The effect of indomethacin on the net intestinal accumulation of fluid induced by Escherichia coli heat-stable (ST) enterotoxin in the infant mouse model was examined. Indomethacin, when administered with ST enterotoxin, caused a striking decrease in net intestinal fluid accumulation. This inhibition of ST activity wa...

journal_title：Infection and immunity

authors： Madsen GL,Knoop FC

更新日期：1978-10-01 00:00:00

abstract：:Viral hepatitis caused by infection with murine hepatitis virus strain A59 has been shown to affect the mitotic response after partial hepatectomy in mice. Normal mice showed a delayed response, whereas nude mice did not show any response, even 5 days after partial hepatectomy. ...

journal_title：Infection and immunity

authors： Carthew P

更新日期：1981-08-01 00:00:00

abstract：:A solid-phase radioimmunoassay, applying whole Mycobacterium leprae as antigen and radiolabeled protein A from Staphylococcus aureus as antibody-detecting reagent, was used for the determination of specific immunoglobulin G (IgG) and IgM antibody responses in leprosy patients. High IgG anti-M. leprae antibody levels w...

journal_title：Infection and immunity

authors： Touw J,Langendijk EM,Stoner GL,Belehu A

更新日期：1982-06-01 00:00:00

abstract：:The method of Garra and Baygorria, for localized antibody production, has been adapted for obtaining high-titered and monospecific antibodies against the murine toxin of Yersinia pestis. A hollow, perforated plastic golf ball surgically implanted under the skin of rabbits induced the formation of a granuloma. When the...

journal_title：Infection and immunity

authors： Hillam RP,Tengerdy RP,Brown GL

更新日期：1974-09-01 00:00:00

abstract：:Immunity to Mycobacterium tuberculosis is dependent upon the generation of a protective gamma interferon (IFN-gamma)-producing T-cell response. Recent studies have suggested that interleukin-6 (IL-6) is required for the induction of a protective T-cell response and that IL-4 may suppress the induction of IFN-gamma. To...

journal_title：Infection and immunity

authors： Saunders BM,Frank AA,Orme IM,Cooper AM

更新日期：2000-06-01 00:00:00

abstract：:Host control of Coxiella burnetii infections is believed to be mediated primarily by activated monocytes/macrophages. The activation of macrophages by cytokines leads to the production of reactive oxygen intermediates (ROI) and reactive nitrogen intermediates (RNI) that have potent antimicrobial activities. The contri...

journal_title：Infection and immunity

authors： Brennan RE,Russell K,Zhang G,Samuel JE

更新日期：2004-11-01 00:00:00

abstract：:We have isolated three genes, ARG57, SER57, and LYS1, on the basis of their function in Candida albicans. A C. albicans transformation vector containing the C. albicans URA3 gene, a Candida ARS sequence, and a portion of the Saccharomyces cerevisiae 2 microns circle containing the replication origin was constructed. C...

journal_title：Infection and immunity

authors： Goshorn AK,Grindle SM,Scherer S

更新日期：1992-03-01 00:00:00

abstract：:Rickettsia rickettsii and R. australis formed infectious antibody complexes when reacted with homologous convalescent serum. The addition of antiglobulin to these complexes showed neutralization of plaques proportional to the concentration of rickettsial immune serum. ...

journal_title：Infection and immunity

authors： Kenyon RH,McManus AT

更新日期：1974-05-01 00:00:00

abstract：:Galactomannan (GM) extracted from mycelia of Aspergillus fumigatus with cold dilute alkali reacted with antiserum specific for an antigen that circulated in invasive aspergillosis in rabbits and humans. The GM was purified by its affinity for concanavalin A and was separated from a nonantigenic glucan by gel permeatio...

journal_title：Infection and immunity

authors： Reiss E,Lehmann PF

更新日期：1979-07-01 00:00:00

abstract：:Archival gastric tissues from 10 of 39 gnotobiotic piglets colonized with Helicobacter pylori 26695 contained stromal leukocytic inflammation along with ulcers and erosions. In contrast, gastric tissues from 54 archival control piglets were devoid of both inflammation and ulcers. These data confirm the hypothesis that...

journal_title：Infection and immunity

authors： Krakowka S,Eaton KA,Rings DM

更新日期：1995-06-01 00:00:00

abstract：:Normal cell polarity protects epithelial cells against Pseudomonas aeruginosa invasion and cytotoxicity. Using epithelial cell clones with selective defects in sorting of membrane constituents, and using hepatocyte growth factor pretreatment, we found that polarized susceptibility to P. aeruginosa can be altered witho...

journal_title：Infection and immunity

authors： Fleiszig SM,Vallas V,Jun CH,Mok L,Balkovetz DF,Roth MG,Mostov KE

更新日期：1998-07-01 00:00:00

abstract：:To characterize the mechanism by which interleukin 10 (IL-10) inhibits Th1 responses to intracellular pathogens, we evaluated the interaction between IL-10 and Mycobacterium tuberculosis-induced gamma interferon (IFN-gamma) production by peripheral blood mononuclear cells from persons across the spectrum of tuberculou...

journal_title：Infection and immunity

authors： Gong JH,Zhang M,Modlin RL,Linsley PS,Iyer D,Lin Y,Barnes PF

更新日期：1996-03-01 00:00:00

abstract：:Mutant cultures that lacked the ability to produce filamentous hemagglutinin were obtained by UV irradiation of Bordetella pertussis strain 18-323. Various biological activities of these mutants were compared with those of the parent culture. It was found that the leukocytosis-promoting, histamine-sensitizing, and mou...

journal_title：Infection and immunity

authors： Watanabe M,Nakase Y

更新日期：1982-03-01 00:00:00

abstract：:Toxoplasma gondii infects both hematopoietic and nonhematopoietic cells and can cause cerebral and ocular toxoplasmosis, as a result of either congenital or postnatally acquired infections. Host protection likely acts at both cellular levels to control the parasite. CD40 is a key factor for protection against cerebral...

journal_title：Infection and immunity

authors： Van Grol J,Muniz-Feliciano L,Portillo JA,Bonilha VL,Subauste CS

更新日期：2013-06-01 00:00:00

abstract：:Polymorphoneutrophils (PMNs) are important effector cells in host defense against pneumonia. However, PMNs can also induce inflammation and tissue damage. To investigate the contribution of PMNs to host defense against pneumococcal pneumonia, we determined the effect of the PMN-depleting rat monoclonal antibody RB6-8C...

journal_title：Infection and immunity

authors： Marks M,Burns T,Abadi M,Seyoum B,Thornton J,Tuomanen E,Pirofski LA

更新日期：2007-04-01 00:00:00

abstract：:Toxic shock syndrome-associated staphylococcal and streptococcal exotoxins were tested for an ability to induce the production of tumor necrosis factor (TNF). Staphylococcal enterotoxins B and C1, along with streptococcal pyrogenic exotoxin A, all induced TNF production in a dose-dependent manner, with production peak...

journal_title：Infection and immunity

authors： Fast DJ,Schlievert PM,Nelson RD

更新日期：1989-01-01 00:00:00

abstract：:The attachment of Staphylococcus aureus (Cowan I) and two strains of group A and G streptococci on glass cover slips coated with fibronectin, fibronectin fragments, or fibrinogen was studied. The attachment was quantitated by counting the attached bacteria on glass surfaces coated with a similar molarity of the protei...

journal_title：Infection and immunity

authors： Kuusela P,Vartio T,Vuento M,Myhre EB

更新日期：1985-10-01 00:00:00

abstract：:Vibrio mimicus 61892, isolated in 1977 from a case of watery diarrhea in Bangladesh, produces an enterotoxin which possesses activity in Y-1 mouse adrenal cells and in rabbit ileal loops which is identical to the prototype cholera toxin (CT) produced by Vibrio cholerae 569B. The neutralization of the adrenal cell acti...

journal_title：Infection and immunity

authors： Spira WM,Fedorka-Cray PJ

更新日期：1983-11-01 00:00:00