Abstract：
:The age-related deterioration in the quality (e.g., strength and fracture resistance) and quantity (e.g., bone-mineral density) of human bone, together with increased life expectancy, is responsible for increasing incidence of bone fracture in the elderly. The present study describes ex vivo fracture experiments to quantitatively assess the effect of aging on the fracture toughness properties of human cortical bone specifically in the transverse (breaking) orientation. Because bone exhibits rising crack-growth resistance with crack extension, the aging-related transverse toughness is evaluated in terms of resistance-curve (R-curve) behavior, measured for bone taken from a wide range of age groups (25-74 years). Using this approach, both the ex vivo crack-initiation and crack-growth toughness are determined and are found to deteriorate with age; however, the effect is far smaller than that reported for the longitudinal toughness of cortical bone. Whereas the longitudinal crack-growth toughness has been reported to be reduced by almost an order of magnitude for human cortical bone over this age range, the corresponding age-related decrease in transverse toughness is merely ~14%. Similar to that reported for X-ray irradiated bone, with aging cracks in the transverse direction are subjected to an increasing incidence of crack deflection, principally along the cement lines, but the deflections are smaller and result in a generally less tortuous crack path.
journal_name
J Mech Behav Biomed Materauthors
Koester KJ,Barth HD,Ritchie ROdoi
10.1016/j.jmbbm.2011.05.020subject
Has Abstractpub_date
2011-10-01 00:00:00pages
1504-13issue
7eissn
1751-6161issn
1878-0180pii
S1751-6161(11)00122-6journal_volume
4pub_type
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