Abstract:
:The cyclohexadepsipeptide beauvericin (BEA) is a mycotoxin produced by the fungus Beauveria bassiana (Bals.). Using ELISA, different accessions of B. bassiana, belonging to distinct genetic groups, were analyzed to determine their variability in BEA production. The cytotoxic effect of pure mycotoxins and crude extracts was also tested on insect cell lines SF-9 and SF-21. The results showed that BEA production was significantly different between all strains. Bb 9024 exhibited the highest levels (98.56 mg/l), while Bb 9001 the lowest (15.66 mg/l). Statistical difference was found when BEA CC(50) values (2.81 and 6.94 μM) were compared with those values from others mycotoxins (4.23-11.95 μM). Although no correlation has been observed between beauvericin production and phylogenetic grouping, the results suggest a comprehensible involvement of these metabolites during the infection process. The biological evaluation of metabolites produce by entomopathogenic fungi provides better criteria to design more effective formulations for pest management.
journal_name
Curr Microbioljournal_title
Current microbiologyauthors
Valencia JW,Gaitán Bustamante AL,Jiménez AV,Grossi-de-Sá MFdoi
10.1007/s00284-011-9977-2subject
Has Abstractpub_date
2011-09-01 00:00:00pages
306-12issue
3eissn
0343-8651issn
1432-0991journal_volume
63pub_type
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