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Specific binding of [3H]heparin to human carcinoma SW-13 and other mammalian cells.

Abstract：

:This study reports on the specific binding of [3H]heparin to human adrenocortical carcinoma cell line SW-13. Heparin binding to SW-13 cells is specific, saturable, and time- and temperature-dependent with maximum binding occurring between 90 and 120 min at 22 degrees C. Scatchard analysis revealed two classes of binding sites. The apparent Kd for high-affinity receptors is 2.14 x 10(-8) M with 1.48 x 10(6) sites per cells. Six other tested mammalian cell lines also have specific binding sites for heparin.

journal_name

Exp Cell Res

journal_title

Experimental cell research

authors

Halper J

doi

10.1016/0014-4827(90)90099-v

subject

Has Abstract

pub_date

1990-04-01 00:00:00

pages

324-7

issue

2

eissn

0014-4827

issn

1090-2422

journal_volume

187

pub_type

杂志文章

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