Surgical procedures in gallbladder cancer with special reference to its macroscopic appearance.

abstract：:Fcγ receptors (FcγRs) on effector cells are of importance for mediating antibody-dependent cellular cytotoxicity (ADCC). FcγRIIIa158valine (V)/phenylalanine (F) and FcγRIIa131histidine (H)/arginine(R) polymorphisms have been shown to relate to prognosis in antibody-treated patients. The aim of the present study was to...

journal_title：International journal of oncology

authors： Wang B,Kokhaei P,Mellstedt H,Liljefors M

更新日期：2010-12-01 00:00:00

abstract：:Gallbladder cancer (GBC) is one of the most unfavorable prognostic tumor, and immediate growth and distant metastasis are important factors associated with the poor prognosis of patients with this disease. Standard and variant isoforms of CD44 are associated with tumor growth, metastasis, and epithelial-mesenchymal tr...

journal_title：International journal of oncology

authors： Miwa T,Nagata T,Kojima H,Sekine S,Okumura T

更新日期：2017-09-01 00:00:00

abstract：:Many traditional healing plants successfully passed several hundred years of empirical testing against specific diseases and thereby demonstrating that they are well tolerated in humans. Although quite a few ethno-pharmacological plants are applied against a variety of conditions there are still numerous plants that h...

journal_title：International journal of oncology

authors： Gridling M,Stark N,Madlener S,Lackner A,Popescu R,Benedek B,Diaz R,Tut FM,Nha Vo TP,Huber D,Gollinger M,Saiko P,Ozmen A,Mosgoeller W,De Martin R,Eytner R,Wagner KH,Grusch M,Fritzer-Szekeres M,Szekeres T,Kopp B,F

更新日期：2009-04-01 00:00:00

abstract：:Acquired drug resistance to chemotherapy is a major problem in the treatment of cancer. After primary surgical intervention, followed by chemotherapy treatments, the majority of patients develop disease recurrence. This is due to tumor cell heterogeneity and genetic instability. In contrast to tumor cells, proliferati...

journal_title：International journal of oncology

authors： Benouchan M,Colombo BM

更新日期：2005-08-01 00:00:00

abstract：:After the publication of the article, the authors have realized that the affiliation presented for the joint co‑author listed on the paper (Jian‑Ren Tu) was incorrect. The correct author list (and affiliations) should therefore have been published as follows: Yu‑Hua Xu1*, Jian‑Ren Tu2*, Tian‑Tian Zhao3, Shi‑Guang Xie3...

journal_title：International journal of oncology

authors： Xu YH,Tu JR,Zhao TT,Xie SG,Tang SB

更新日期：2019-07-01 00:00:00

abstract：:We have utilized a series of glioma cell lines to study the effects of ionizing radiation on the regulation of proteins that contribute to cell cycle progression. While no alterations of cyclin E or cdk4 were detected, a high percentage of glioma cell lines exhibited constitutive overexpression of cdk2 protein and abe...

journal_title：International journal of oncology

authors： Pykett M,Azzam E,Little J

更新日期：1997-01-01 00:00:00

abstract：:alpha-tocopheryl phosphate (TocP) has been elucidated for diverse effectiveness through unequivocal mechanisms independent of its conversion to alpha-tocopherol (Toc). The present study showed that TocP, in a dose-dependent manner, repressed invasion of human fibrosarcoma HT-1080 cells through the basement membrane, m...

journal_title：International journal of oncology

authors： Saitoh Y,Yumoto A,Miwa N

更新日期：2009-12-01 00:00:00

abstract：:Selectivity of the anticancer agent PB-100 for malignant cells, already demonstrated using cell growth and viability evaluation, is now confirmed by microscopic observations. PB-100 is easily detected inside cells by its yellow color under visible light and by its blue fluorescence; it may be measured in isolated nucl...

journal_title：International journal of oncology

authors： Beljanski M,Crochet S

更新日期：1995-07-01 00:00:00

abstract：:A camptothecin (CPT) formulation that can be easily administered, is less toxic, and has greater antitumor effect is needed. In this study, a water-soluble CPT derivative was obtained by direct coupling of CPT to poly(L-glutamic acid) (PG) through the C20(S)-hydroxyl group. CPT was released from the resulting conjugat...

journal_title：International journal of oncology

authors： Zou Y,Wu QP,Tansey W,Chow D,Hung MC,Charnsangavej C,Wallace S,Li C

更新日期：2001-02-01 00:00:00

abstract：:Loss of E-cadherin and catenin expression may be associated with distant and lymph node metastases in breast cancer. Heterogeneity of E-cadherin expression is associated with poor prognosis, suggesting that E-cadherin and catenins may serve as useful prognostic markers for invasive breast carcinoma. Reduction or loss ...

journal_title：International journal of oncology

authors： Yoshida R,Kimura N,Harada Y,Ohuchi N

更新日期：2001-03-01 00:00:00

abstract：:Macrophages activated by lipopolysaccharide or interferon-gamma have been shown to be cytotoxic to tumor cells by releasing nitric oxide. Here, we report that unstimulated rat alveolar macrophages cultured with certain tumor cells produce nitric oxide and are cytotoxic to these tumor cells. Alveolar macrophages were t...

journal_title：International journal of oncology

authors： Nozaki Y,Isobe K,Nakashima I,Shimokata K

更新日期：1993-06-01 00:00:00

abstract：:Dihydropyrimidine dehydrogenase (DPD) is the first and rate-limiting enzyme in the degradation of pyrimidines and pyrimidine base analogs including the anticancer drugs 5-fluorouracil (5-FU) and Xeloda. A decreased DPD enzyme activity has been described in cancer patients experiencing severe and life-threatening toxic...

journal_title：International journal of oncology

authors： Gross E,Seck K,Neubauer S,Mayr J,Hellebrand H,Ratanaphan A,Lutz V,Stockinger H,Kiechle M

更新日期：2003-02-01 00:00:00

abstract：:To overcome the poor tumor transduction efficiency of adenovirus serotype 5 (Ad5) observed in several types of cancer, the fiber region of Ad5, apart from its tail, was replaced by adenovirus serotype 35 (Ad35). The chimeric Ad5/F35 adenoviral vector did not exhibit any significant enhancement of transduction efficien...

journal_title：International journal of oncology

authors： Kim SY,Kang S,Song JJ,Kim JH

更新日期：2013-04-01 00:00:00

abstract：:It has been reported that suppression of selenium‑binding protein 1 (SBP1) occurs in many human malignancies which is considered to play an important role in cancer development and progression. Despite its importance in cancer, the function and factors that regulate its expression are not known. Using cell proliferati...

journal_title：International journal of oncology

authors： Zhang C,Xu W,Pan W,Wang N,Li G,Fan X,Xu X,Shen S,Das UN

更新日期：2013-05-01 00:00:00

abstract：:We demonstrated previously that rat ascites hepatoma MM1 cells require both lysophosphatidic acid (LPA) and fibronectin (FN) for phagokinetic motility and transcellular migration and that these events are regulated through the RhoA-ROCK pathway and tyrosine phosphorylation of proteins including focal adhesion kinase (...

journal_title：International journal of oncology

authors： Mukai M,Iwasaki T,Tatsuta M,Togawa A,Nakamura H,Murakami-Murofushi K,Kobayashi S,Imamura F,Inoue M

更新日期：2003-06-01 00:00:00

abstract：:High-mobility group AT-hook protein 2 (HMGA 2) is a transcription factor associated with malignancy and poor prognosis in a variety of human cancers. We correlated HMGA 2 expression with clinical parameters, survival, and O-6-methylguanine-DNA methyltransferase methylation status (MGMT) in glioblastoma patients. HMGA ...

journal_title：International journal of oncology

authors： Schwarm FP,Uhle F,Schänzer A,Acker T,Stein M,Reinges MH,Weischer C,Weigand MA,Uhl E,Kolodziej MA

更新日期：2016-04-01 00:00:00

abstract：:In recent years major progress has been made in understanding the molecular steps of death receptor and mitochondrial pathway of apoptosis. Mechanisms of NF-kappaB-mediated survival (anti-apoptotic) signal have been delineated. A novel anti-apoptotic mechanism of FLIP in the recruitment of RIP and TRAF-1 and TRAF-2 to...

journal_title：International journal of oncology

authors： Gupta S

更新日期：2003-01-01 00:00:00

abstract：:Advanced castration-resistant prostate cancer has high mortality rates and limited treatment options. Novel therapies are needed to better contend with this disease. Polysaccharide-K® (PSK), an extract of the mushroom Trametes versicolor, has immunomodulatory and tumor suppressive a...

journal_title：International journal of oncology

authors： Wenner CA,Martzen MR,Lu H,Verneris MR,Wang H,Slaton JW

更新日期：2012-04-01 00:00:00

abstract：:Emerging evidence indicates that mesenchymal stem cells (MSCs) serve an indispensable role in the tumor microenvironment. However, whether MSCs participate in the development of oral carcinogenesis remains unclear. The present study isolated MSCs from clinical tissues and investigated the differences of MSCs derived f...

journal_title：International journal of oncology

authors： Li W,Han Y,Zhao Z,Ji X,Wang X,Jin J,Wang Q,Guo X,Cheng Z,Lu M,Wang G,Wang Y,Liu H

更新日期：2019-05-01 00:00:00

abstract：:The aim of the present study was to assess whether (-)-epigallocatechin 3-gallate (EGCG) via epigenetic modifications, regulates Raf kinase inhibitor protein (RKIP) expression and invasive metastatic activity in AsPC-1 pancreatic adenocarcinoma cells. Basal levels of RKIP were examined in various human pancreatic canc...

journal_title：International journal of oncology

authors： Kim SO,Kim MR

更新日期：2013-01-01 00:00:00

abstract：:Tumour growth is frequently associated with massive loss of body weight and negative nitrogen balance leading to cachexia, one of the worst features of malignancy accounting for nearly two thirds of cancer deaths. At the metabolic level, cachexia is associated with depletion of body lipid stores as well as loss of ske...

journal_title：International journal of oncology

authors： Argilés JM,Costelli P,Carbó N,Pallarés-Trujillo J,López-Soriano FJ

更新日期：1999-03-01 00:00:00

abstract：:Recent investigations have demonstrated that polyphenolic catechins inhibit cancer cell proliferation and tumor growth. However, how the major active component of tea catechins, epigallocatechin-3 gallate (EGCG), mediates anticancerous effects has not been extensively examined. We have investigated the cell growth inh...

journal_title：International journal of oncology

authors： Tang Y,Zhao DY,Elliott S,Zhao W,Curiel TJ,Beckman BS,Burow ME

更新日期：2007-10-01 00:00:00

abstract：:Malignant pleural mesothelioma (MPM) is a rare and aggressive form of cancer commonly associated with asbestos exposure that stems from the thoracic mesothelium with high mortality rate. Currently, treatment options for MPM are limited, and new molecular targets for treatments are urgently needed. Using quantitative r...

journal_title：International journal of oncology

authors： Kato T,Lee D,Wu L,Patel P,Young AJ,Wada H,Hu HP,Ujiie H,Kaji M,Kano S,Matsuge S,Domen H,Kaga K,Matsui Y,Kanno H,Hatanaka Y,Hatanaka KC,Matsuno Y,de Perrot M,Yasufuku K

更新日期：2016-08-01 00:00:00

abstract：:A series of different human MDR (multidrug-resistant) cell lines including a HeLa-MDR1 transfectant which exhibit high overexpression of the MDR1/P-glycoprotein gene, but no enhanced expression of the MRP (multidrug resistance associated protein) gene, showed different ratios of relative resistances to the taxanes tax...

journal_title：International journal of oncology

authors： Ise W,Heuser M,Sanders K,Beck J,Gekeler V

更新日期：1996-05-01 00:00:00

abstract：:Voltage-gated potassium (Kv) channels play important roles in differentiation and growth of non-excitable cells. Inhibition of these channels is also known to suppress proliferation of various cancer cells. Here we examine expression of K+ channel subunit genes in various uterine cancer cells and their roles in cell p...

journal_title：International journal of oncology

authors： Suzuki T,Takimoto K

更新日期：2004-07-01 00:00:00

abstract：:The tumor suppressor protein p53 is one of the most important manipulators of the cell cycle. By interaction with targets such as WAF1/CIP1, mdm2 or GADD45 p53 functions as a negative or positive regulator of the cell cycle. After DNA damage p53 is implicated in growth arrest of cells in the G(1) phase of the cell cyc...

journal_title：International journal of oncology

authors： Gotz C,Montenarh M

更新日期：1995-05-01 00:00:00

abstract：:Cervical lymph node metastasis is the most common recurrence pattern of head and neck squamous cell carcinoma (HNSCC), and it is usually treated with radiation therapy and/or neck dissection. There has long been a desire for markers useful in predicting radiosensitivity to enable assignment of patients with recurrent ...

journal_title：International journal of oncology

authors： Ito Y,Kamijo T,Yokose T,Kawashima M,Ogino T,Ikeda H,Hayashi R,Sasaki S,Ochiai A

更新日期：2001-12-01 00:00:00

abstract：:A novel amphibian oocyte RNase, ONCONASE(R) (ONC), has been previously shown to have synergistic tumor cell growth inhibitory activity when combined with tamoxifen (TMX) and/or trifluoperazine (TFP) in human ASPC-1 pancreatic and A-549 lung carcinoma cells, respectively. It has recently been reported that several drug...

journal_title：International journal of oncology

authors： Mikulski S,Viera A,Shogen K

更新日期：1993-05-01 00:00:00

abstract：:Sonic hedgehog (SHH), Indian hedgehog (IHH) and Desert hedgehog (DHH) are Hedgehog family ligands, which play key roles in embryogenesis and carcinogenesis, especially in pancreatic cancer and gastric cancer. Drosophila Costal-2 (Cos2) is a Hedgehog signaling regulator, interacting with Smoothened (Smo), Cubitus inter...

journal_title：International journal of oncology

authors： Katoh Y,Katoh M

更新日期：2004-12-01 00:00:00

abstract：:In the present study, we have investigated a combination of photodynamic therapy (PDT) using 5-aminolevulinic acid (ALA) and simultaneous hyperthermia (HT) on osteosarcoma (HOSM-1) cells, squamous cell carcinoma (KB) cells and fibroblasts (HF), including an assessment of the differences in the sensitivity of these cel...

journal_title：International journal of oncology

authors： Yanase S,Nomura J,Matsumura Y,Nagai K,Kinoshita M,Nakanishi H,Ohnishi Y,Tokuda T,Tagawa T

更新日期：2005-07-01 00:00:00