[Corrigendum] Overexpression of lncRNA EGFR‑AS1 is associated with a poor prognosis and promotes chemotherapy resistance in non‑small cell lung cancer.

abstract：:Malignant pleural mesothelioma (MPM) is an aggressive cancer for which more effective treatments are needed. In this study, strong to moderate staining of MET and ERK5 was detected in 67.1 and 48% of the analyzed 73 human mesothelioma tumors, and significant correlation of MET and ERK5 expression was identified (P<0.0...

journal_title：International journal of oncology

authors： Wang H,Dai YY,Zhang WQ,Hsu PC,Yang YL,Wang YC,Chan G,Au A,Xu ZD,Jiang SJ,Wang W,Jablons DM,You L

更新日期：2017-07-01 00:00:00

abstract：:Sialyl Le(a) antigen (CA19-9), a member of a family of high molecular weight glycoproteins, was originally described as a gastrointestinal- and pancreatic-specific tumor marker. Recent studies have demonstrated that sialyl Le(a) is a ligand for E-selectin and may play an important role in tumor metastasis. However, ex...

journal_title：International journal of oncology

authors： Oshiba G,Kijima H,Tanaka H,Kenmochi T,Himeno S,Kise Y,Nishi T,Chino O,Shimada H,Abe Y,Yamazaki H,Nakamura M,Ueyama Y,Tanaka M,Makuuchi H

更新日期：2000-10-01 00:00:00

abstract：:We previously reported that podophyllotoxin acetate (PA) radiosensitizes NCI-H460 cells. Here, we confirmed that PA treatment also induces cell death among two other non-small cell lung cancer (NSCLC) cell lines: NCI-H1299 and A549 cells (IC50 values = 7.6 and 16.1 nM, respectively). Our experiments further showed tha...

journal_title：International journal of oncology

authors： Choi JY,Hong WG,Cho JH,Kim EM,Kim J,Jung CH,Hwang SG,Um HD,Park JK

更新日期：2015-10-01 00:00:00

abstract：:Pyrogallol (PG) inhibits the growth of various cells via stimulating O2•--mediated death. This study investigated the effects of PG on cell death in human pulmonary fibroblast (HPF) cells in relation to reactive oxygen species (ROS) and glutathione (GSH) levels. PG inhibited the growth of HPF cells with an IC50 of ~50...

journal_title：International journal of oncology

authors： Park WH

更新日期：2016-08-01 00:00:00

abstract：:The efficacy of resveratrol as a preventive agent against the growth of t(4;11) acute lymphoblastic leukemia (ALL) was evaluated in NOD.CB17-Prkdcscid/J mice engrafted with the human t(4;11) ALL SEM cell line. SEM cells were injected into the tail vein and engraftment was monitored ...

journal_title：International journal of oncology

authors： Zunino SJ,Storms DH,Newman JW,Pedersen TL,Keen CL,Ducore JM

更新日期：2012-04-01 00:00:00

abstract：:Conventional chemotherapy produces varying degrees of response in patients with many advanced cancers and has significant side effects. Receptors for luteinizing hormone-releasing hormone (LH-RH) are present in a high percentage of human ovarian, prostatic, breast and endometrial tumors and targeted chemotherapy based...

journal_title：International journal of oncology

authors： Lamharzi N,Halmos G,Armatis P,Schally AV

更新日期：1998-03-01 00:00:00

abstract：:The support mechanisms that are involved in lymph-node metastasis of oral squamous cell carcinoma (OSCC) remain largely unknown. Recent studies have demonstrated that tumor cells express chemokine receptors and use chemokines to metastasize to the target organ in many malignancies in humans. In this study, we examined...

journal_title：International journal of oncology

authors： Ishikawa T,Nakashiro K,Hara S,Klosek SK,Li C,Shintani S,Hamakawa H

更新日期：2006-01-01 00:00:00

abstract：:Overexpression of either of the multidrug resistance genes MDR1 and MRP is associated with resistance of tumors to multiple chemotherapeutic agents. Overexpression of MDR1 has been reported in some cell lines derived from human hepatocellular carcinomas (HCC) and hepatoblastomas (HB). The human gene for cMOAT (

journal_title：International journal of oncology

authors： Minemura M,Tanimura H,Tabor E

更新日期：1999-09-01 00:00:00

abstract：:This retrospective study looks at the differences between adolescents (15-19 years) and young adults (20-25 years), diagnosed with Hodgkin lymphoma and treated at the same adult institution. Outcome according to risk category was evaluated, and although there were no significant differences in the whole cohort, or low...

journal_title：International journal of oncology

authors： Herbertson RA,Evans LS,Hutchinson J,Horsman J,Hancock BW

更新日期：2008-07-01 00:00:00

abstract：:A chromosomal break indicates a double-stranded DNA break of the chromatin fiber. Cytogenetic observations can enumerate chromosome breaks but cannot detect single-stranded DNA breaks (nicks). When a high frequency of chromosomal breaks occurs in a cell population, whether spontaneously occurred or mutagen induced, a ...

journal_title：International journal of oncology

authors： Wang R,Hsu T,Liang J

更新日期：1993-06-01 00:00:00

abstract：:The development of targeted molecular therapies has greatly benefited patients with lung adenocarcinomas. In contrast, these treatments have had little benefit in the management of lung squamous cell carcinoma (lung SCC). Therefore, new treatment options based on current genomic approaches are needed for lung SCC. Abe...

journal_title：International journal of oncology

authors： Kumamoto T,Seki N,Mataki H,Mizuno K,Kamikawaji K,Samukawa T,Koshizuka K,Goto Y,Inoue H

更新日期：2016-11-01 00:00:00

abstract：:Previous studies have revealed that protein kinase C (PKC) is responsible for malignant progression. In the present study, we investigated the potent inhibitory effects of an antiestrogen, toremifene, on PKC-mediated cellular adhesion. A phorbol ester, phorbol 12-myristate 13-acetate (PMA), significantly enhanced alph...

journal_title：International journal of oncology

authors： Maemura M,Iino Y,Horiguchi J,Takei H,Horii Y,Koibuchi Y,Yokoe T,Takeyoshi I,Ohwada S,Morishita Y

更新日期：1998-11-01 00:00:00

abstract：:Cancer-associated fibroblasts (CAFs) are key determinants in the malignant progression of cancer, supporting tumorigenesis and metastasis. CAFs also mediate epithelial to mesenchymal transition (EMT) in tumor cells and their achievement of stem cell traits. Curcumin has recently been found to possess anticancer activi...

journal_title：International journal of oncology

authors： Du Y,Long Q,Zhang L,Shi Y,Liu X,Li X,Guan B,Tian Y,Wang X,Li L,He D

更新日期：2015-12-01 00:00:00

abstract：:MicroRNA‑301a (miRNA/miR‑301a) and nuclear factor (NF)‑κB signaling play important roles in tumor invasion, migration and progression. However, the role of miRNA‑301a‑3p in human gastric cancer (GC), and specifically in the activation of NF‑κB signaling, remains unclear. The aim of the present study was to investigate...

journal_title：International journal of oncology

authors： Xu X,Xia Y,Ma J,Li W,Niu N,Li X,Tao H,Xu J,He X

更新日期：2020-08-01 00:00:00

abstract：:In the present study, we analyzed the proliferation and cytotoxic activities of LAK cells and initial phase TILs by stimulation with IL-4. IL-4 obviously inhibited the DNA synthesis of LAK cells and initial phase TILs at the concentration of 250 pg/ml and 25 pg/ml, respectively. Furthermore, IL-4 (25 ng/ml for LAK cel...

journal_title：International journal of oncology

authors： Tsunoda T,Tanimura H,Yamaue H,Iwahashi M,Tani M,Tamai M,Noguchi K,Mizobata S,Arii K

更新日期：1995-11-01 00:00:00

abstract：:Human breast epithelial MCF10AT cells injected with Matrigel into the subcutis of nude/beige mice form simple ducts which, with time, resemble human proliferative breast disease and sporadically progress to carcinoma. Basement membrane was visualized with a silver stain and myoepithelial cells detected by their reacti...

journal_title：International journal of oncology

authors： Tait L,Dawson P,Wolman S,Galea K,Miller F

更新日期：1996-08-01 00:00:00

abstract：:Although a correlation between anaplasia and mutations of the p53 tumor suppressor gene has been found in Wilms' tumor (WT) a prognostic significance of p53 in WT remains largely unresolved. The goal of this study was to obtain a better understanding of the role of p53 expression in WT. Immunohistochemical analysis wa...

journal_title：International journal of oncology

authors： Beniers AJ,Efferth T,Füzesi L,Granzen B,Mertens R,Jakse G

更新日期：2001-01-01 00:00:00

abstract：:Lymph node metastasis of breast cancer is a clinical marker of poor prognosis. Yet, there exist no therapies targeting mechanisms of intravasation into lymphatics. Herein we report on an effect of the antidyslipidemic drug fenofibrate with vasoprotective activity, which attenuates breast cancer intravasation in vitro,...

journal_title：International journal of oncology

authors： Nguyen CH,Huttary N,Atanasov AG,Chatuphonprasert W,Brenner S,Fristiohady A,Hong J,Stadler S,Holzner S,Milovanovic D,Dirsch VM,Kopp B,Saiko P,Krenn L,Jäger W,Krupitza G

更新日期：2017-05-01 00:00:00

abstract：:Adrenomedullin (AM) is a multifunctional 52-amino acid peptide. AM has several effects and acts as a growth factor in several types of cancer cells. Our previous study revealed that an AM antagonist (AMA) suppressed the growth of pancreatic tumors in mice, although its mechanism was not elucidated. In this study, we c...

journal_title：International journal of oncology

authors： Tsuchiya K,Hida K,Hida Y,Muraki C,Ohga N,Akino T,Kondo T,Miseki T,Nakagawa K,Shindoh M,Harabayashi T,Shinohara N,Nonomura K,Kobayashi M

更新日期：2010-06-01 00:00:00

abstract：:In the present study, we report the utility of transrectal ultrasonography guidance for laparoscopic radical prostatectomy (LRP), and the effect of a novel surgical approach of 'seven key elements of operative skill for the early recovery of urinary continence' ('7 key elements'). Among 170 patients who underwent lapa...

journal_title：International journal of oncology

authors： Azuma H,Ibuki N,Inamoto T,Koyama K,Utimoto S,Fujisue Y,Mizutani Y,Nomi H,Ubai T,Katsuoka Y

更新日期：2011-02-01 00:00:00

abstract：:Narrow band imaging (NBI) has been used in the gastrointestinal endoscopy field as a novel endoscopic imaging technique and has contributed to improved qualitative diagnosis and detection of lesions. However, there are only a few studies of use of NBI in the gynecology field. We applied NBI in flexible hysteroscopy at...

journal_title：International journal of oncology

authors： Kisu I,Banno K,Kobayashi Y,Ono A,Masuda K,Ueki A,Nomura H,Hirasawa A,Abe T,Kouyama K,Susumu N,Aoki D

更新日期：2011-11-01 00:00:00

abstract：:Cervical lymph node metastasis is the most common recurrence pattern of head and neck squamous cell carcinoma (HNSCC), and it is usually treated with radiation therapy and/or neck dissection. There has long been a desire for markers useful in predicting radiosensitivity to enable assignment of patients with recurrent ...

journal_title：International journal of oncology

authors： Ito Y,Kamijo T,Yokose T,Kawashima M,Ogino T,Ikeda H,Hayashi R,Sasaki S,Ochiai A

更新日期：2001-12-01 00:00:00

abstract：:Since the efficacy of chemotherapy can be enhanced by targeting to specific receptors on tumors, we investigated the expression of LH-RH receptors in 5 human colon cancer lines and the effects of cytotoxic LH-RH analogs on these tumors. Nude mice bearing HT-29, HCT-116, HCT-15, LoVo and Colo-320DM cancers were treated...

journal_title：International journal of oncology

authors： Szepeshazi K,Schally AV,Halmos G

更新日期：2007-06-01 00:00:00

abstract：:This study suggests that speckle-type POZ protein (SPOP) may be a tumor suppressor gene and its prognostic value in human glioma. Real-time quantitative RT-PCR (qRT‑PCR), western blotting, and immunohistochemical staining were used to examine SPOP expression in glioma tissues and normal brain (NB) tissues. The relatio...

journal_title：International journal of oncology

authors： Ding D,Song T,Jun W,Tan Z,Fang J

更新日期：2015-01-01 00:00:00

abstract：:We have previously investigated the possibility of using hypericin as a diagnostic tool for the fluorescence detection of flat bladder carcinoma. In these clinical studies, it was shown that following intravesical application in humans, hypericin becomes selectively localized in transitional papillary carcinoma and ca...

journal_title：International journal of oncology

authors： Kamuhabwa AA,Roskams T,Baert L,De Witte PA

更新日期：2003-04-01 00:00:00

abstract：:The objective of this study was to assess the toxicity and immunological response induced by autologous dendritic cells (DCs) pulsed with allogeneic tumor lysate in a pancreatic cancer patient. The lack of available tumor peptides in pancreatic cancer strongly supports the idea to use allogeneic tumor cells as a sourc...

journal_title：International journal of oncology

authors： Stift A,Friedl J,Dubsky P,Bachleitner-Hofmann T,Benkoe T,Brostjan C,Jakesz R,Gnant M

更新日期：2003-03-01 00:00:00

abstract：:Selectivity of the anticancer agent PB-100 for malignant cells, already demonstrated using cell growth and viability evaluation, is now confirmed by microscopic observations. PB-100 is easily detected inside cells by its yellow color under visible light and by its blue fluorescence; it may be measured in isolated nucl...

journal_title：International journal of oncology

authors： Beljanski M,Crochet S

更新日期：1995-07-01 00:00:00

abstract：:An altered expression of microRNAs (miRNAs) contributes both to the development of cancer and to the progression of the disease. Malignant tumours and tumour cell lines have widespread deregulated expressions of miRNAs compared to normal tissues. In this study, we investigated the expression profiles of 340 mammalian ...

journal_title：International journal of oncology

authors： D'Urso PI,D'Urso OF,Storelli C,Mallardo M,Gianfreda CD,Montinaro A,Cimmino A,Pietro C,Marsigliante S

更新日期：2012-07-01 00:00:00

abstract：:The impacts of post‑operative abdominal infectious complications increase hematogenous distant metastasis and result in poor long‑term survival after curative resection. Even if curative resection can be performed, the presence of circulating tumor cells is affected. The liver, the most common site of metastases, is a...

journal_title：International journal of oncology

authors： Okazaki M,Yamaguchi T,Tajima H,Fushida S,Ohta T

更新日期：2020-10-01 00:00:00

abstract：:Currently, some evidence suggests that human multipotential mesenchymal stems cells (hMSCs) aid tumor growth and metastasis. Nutrient deprivation and oxygen deficiency are representative characteristics of solid tumor microenvironment during the cancer development. Because the effects of hMSCs on tumors under stressfu...

journal_title：International journal of oncology

authors： Zhang MH,Hu YD,Xu Y,Xiao Y,Luo Y,Song ZC,Zhou J

更新日期：2013-04-01 00:00:00