Abstract:
OBJECTIVE:To reassess the predictive value of detecting sperm cells in men with AZFb or AZFb-c deletions. DESIGN:Retrospective analysis of previously reported men with AZFb or AZFb-c deletions and the addition of six new cases. SETTING:Fertility institution. PATIENT(S):Men with both sequence tagged site marker identification and testicular cytology/histology findings. INTERVENTION(S):Systematic review of reported men with microdeletions that included eligibility, data extraction and analysis. MAIN OUTCOME MEASURE(S):Availability of sperm cells for intracytoplasmic sperm injection (ICSI) in men with AZFb/AZFb-c microdeletions. RESULT(S):The average prevalences reported for AZFb, AZFb-c, partial AZFb, and partial AZFb-c in azoospermic men were 0.9%±0.07%, 2.7%±0.93%, 1.23%±0.9%, and 1%±0.6%, respectively. Sperm cells were identified in 7% and 3% of the 28 and 71 men with complete AZFb and AZFb-c and in 57% and 43% of the 14 and 7 men with partial AZFb and AZFb-c deletions, respectively. The likelihood of finding sperm cells in men with complete versus partial AZFb and AZFb-c deletions was significantly lower. As yet, no clinical or chemical pregnancy after ICSI in cases with complete AZFb/b-c microdeletions has been reported. CONCLUSION(S):Determining the extent of AZFb or AZFb-c deletions is critical considering the frequency and the reasonable prospect of finding sperm cells in partial AZFb/AZFb-c deletions. Referring men with complete AZFb/b-c microdeletions to testicular sperm extraction/ICSI programs should be revaluated.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Kleiman SE,Yogev L,Lehavi O,Hauser R,Botchan A,Paz G,Yavetz H,Gamzu Rdoi
10.1016/j.fertnstert.2011.01.162subject
Has Abstractpub_date
2011-05-01 00:00:00pages
2005-12, 2012.e1-4issue
6eissn
0015-0282issn
1556-5653pii
S0015-0282(11)00241-Xjournal_volume
95pub_type
杂志文章,评审abstract::Twenty-seven sexually mature Japanese monkeys (Macaca fuscata fuscata) weighing 6 to 8 kg were used to evaluate and characterize the local and systemic effects of a T-shaped progesterone-releasing system (UTS) following transabdominal insertion into the uterus. None of five experimental animals conceived, while four o...
journal_title:Fertility and sterility
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abstract:OBJECTIVE:To harmonize the collection of nonsurgical clinical and epidemiologic data relevant to endometriosis research, allowing large-scale collaboration. DESIGN:An international collaboration involving 34 clinical/academic centers and three industry collaborators from 16 countries on five continents. SETTING:In 20...
journal_title:Fertility and sterility
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doi:10.1016/j.fertnstert.2014.07.1244
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abstract::Forty-seven patients at high risk for ovarian hyperstimulation syndrome because of markedly elevated serum E2 levels on either long-luteal or microdose flare leuprolide acetate regimens were treated with ganirelix acetate. Despite being pretreated with GnRH agonist and without withholding gonadotropins, serum E2 decre...
journal_title:Fertility and sterility
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doi:10.1016/j.fertnstert.2005.07.1291
更新日期:2006-01-01 00:00:00
abstract::Twelve human uteri containing intrauterine contraceptive devices (IUDs) and ten uteri without IUDs were obtained at hysterectomy. Samples of fluid were collected from the uterine lumina by absorbing the fluid in small pieces of lens paper. In the samples of luminal fluid we measured the concentration of beta-galactosi...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)42078-9
更新日期:1976-09-01 00:00:00
abstract::Female mice were superovulated with pregnant mare serum gonadotropin (PMSG) and human chorionic gonadotropin (hCG) and mated with male mice. One-cell (n = 429) and 2-cell (n = 450) embryos were collected 20 and 42 hours after hCG and cultured in Ham's F-10 medium (Gibco, Grand Island, NY) (282 mOsm/l, pH 7.4) and in m...
journal_title:Fertility and sterility
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更新日期:1988-03-01 00:00:00
abstract::Women bear the predominant burden of our obesogenic environment, with a higher incidence of obesity than men, more impact on their fertility and success with treatment, and significant maternal and perinatal morbidity and mortality. In this series, the causes, consequences, and solutions regarding the obesity pandemic...
journal_title:Fertility and sterility
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doi:10.1016/j.fertnstert.2017.02.110
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:To study the apparent association between interstitial fallopian tube polyps and isthmic tubal dilatation. DESIGN:Retrospective clinical study. SETTING:Tertiary academic medical center. PATIENT(S):Sixty-five patients with normal hysterosalpingograms and 40 patients with interstitial tubal polyps (25 unilat...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2004.10.049
更新日期:2005-05-01 00:00:00
abstract:OBJECTIVE:To determine the effects of chilling on the organization and distribution of tubulin and chromosomes in rhesus monkey oocytes. DESIGN:Comparative laboratory study. SETTING:Academic research laboratory. ANIMAL(S):Eight adult female rhesus monkeys (Macaca mulatta) aged 6-16 years. INTERVENTION(S):A total of...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(01)03240-x
更新日期:2002-04-01 00:00:00
abstract:OBJECTIVE:To demonstrate a new approach for performing an ovarian cystectomy via transvaginal natural orifice transluminal endoscopic surgery (vNOTES) as an alternative for a laparoscopic ovarian cystectomy. DESIGN:Stepwise explanation of the technique using original video footage. SETTING:Hospital. PATIENT(S):Fourt...
journal_title:Fertility and sterility
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更新日期:2018-02-01 00:00:00
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journal_title:Fertility and sterility
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更新日期:1995-04-01 00:00:00
abstract::This case-control study evaluated the effect of hysteroscopically identified endometrial polyps on endometrium by means of HOXA10 and HOXA11, known molecular markers of endometrial receptivity. Uteri with endometrial polyps demonstrated a marked decrease in HOXA10 and HOXA11 messenger RNA levels, which may impair impl...
journal_title:Fertility and sterility
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doi:10.1016/j.fertnstert.2010.12.034
更新日期:2011-06-30 00:00:00
abstract:OBJECTIVE:To determine the impact of hydrosalpinx on pregnancy rates in patients undergoing IVF for infertility caused by tubal disease. DESIGN:Review of the records of all patients who had undergone IVF for tubal factor infertility at our institution between May 1988 and October 1994. SETTING:A university-sponsored,...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(97)80079-9
更新日期:1997-03-01 00:00:00
abstract:OBJECTIVE:To assess the association of total isoflavone intake with ovulatory function, including sporadic anovulation in healthy premenopausal women. DESIGN:Prospective cohort study. SETTING:University. PATIENT(S):Participants included 259 healthy regularly menstruating women aged 18-44 years. INTERVENTION(S):None...
journal_title:Fertility and sterility
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更新日期:2013-12-01 00:00:00
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journal_title:Fertility and sterility
pub_type: 杂志文章,meta分析
doi:10.1016/j.fertnstert.2018.06.025
更新日期:2018-10-01 00:00:00
abstract::A specially designed rigid salpingoscope has been developed to allow inspection of the tubal mucosa during laparoscopy. The presence and extent of intratubal adhesion formation can be evaluated more accurately by this technique than by either HSG or laparoscopy. In 22 patients with bilateral hydrosalpinges, an intraut...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)60501-0
更新日期:1989-02-01 00:00:00
abstract:OBJECTIVE:To determine whether advanced sperm retrieval is appropriate in cases of obstructive and nonobstructive azoospermia. DESIGN:Prospective controlled study. SETTING:Tertiary care center. PATIENT(S):Men with obstructive and nonobstructive azoospermia, and their partners. INTERVENTION(S):Surgical sperm retriev...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(99)00298-8
更新日期:1999-09-01 00:00:00
abstract:OBJECTIVE:To review the use of radiotherapy for relieving the symptoms of recurrent endometriosis caused by functioning ovarian remnants. DESIGN:Retrospective study (case report). PATIENT(S):A woman with recurrent endometriosis of 14 years' duration. INTERVENTION(S):After hysterectomy and bilateral oophorectomy, hor...
journal_title:Fertility and sterility
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更新日期:1997-11-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the effect of baseline complex ovarian cysts on controlled ovarian hyperstimulation and in vitro fertilization (IVF) outcome. DESIGN:Retrospective analysis with stratification by stimulation regimen and the presence or absence of surgically documented endometriosis. PATIENTS:Two hundred s...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1992-06-01 00:00:00
abstract:OBJECTIVE:To standardize and validate an assay for reactive oxygen species (ROS) in human semen. DESIGN:ROS levels assayed in blanks, negative and positive control samples (30% H2O2), and human semen, with the use of a luminol-based chemiluminescence assay measured in a single tube luminometer. SETTING:Andrology labo...
journal_title:Fertility and sterility
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更新日期:2014-12-01 00:00:00
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journal_title:Fertility and sterility
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更新日期:2019-07-01 00:00:00
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journal_title:Fertility and sterility
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journal_title:Fertility and sterility
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更新日期:1999-12-01 00:00:00
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journal_title:Fertility and sterility
pub_type: 杂志文章,多中心研究
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更新日期:2019-11-01 00:00:00
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journal_title:Fertility and sterility
pub_type: 杂志文章,多中心研究
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更新日期:2010-09-01 00:00:00
abstract:OBJECTIVE:To assess the clinical relevance of daily hormonal changes for achieving a successful pregnancy in anovulatory infertile women. DESIGN:A comparative study of hormonal dynamics in pregnant and nonpregnant cycles during the pulsatile subcutaneous administration of hMG. Subjects received subcutaneous injection ...
journal_title:Fertility and sterility
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更新日期:1993-08-01 00:00:00
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journal_title:Fertility and sterility
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更新日期:2010-06-01 00:00:00
abstract::An antiserum raised against human epididymal proteins associated with ejaculated sperm was used to test the hypothesis that the amount and/or localization of these antigens may be altered in men with infertility. With the use of immunofluorescence we found that in sperm from fertile donors 88.4% of the cells had the a...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1987-02-01 00:00:00
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更新日期:2016-02-01 00:00:00
abstract::Turner syndrome (TS), which affects approximately 1 in 2,500 live-born females, is characterized by loss or structural anomalies of an X chromosome. Clinical features vary among patients; multiple organ systems can be affected. Endocrinologists are involved in the management of short stature, delayed puberty, and infe...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
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更新日期:2012-10-01 00:00:00
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更新日期:2018-02-01 00:00:00