Abstract:
:In the last few years, considerable interest has been aroused in the treatment of chronic obstructive pulmonary disease (COPD) and the dearth of therapeutic options has been replaced by a far more proactive treatment approach, reflected in the development of the various guidelines and recommendations of the scientific societies. There are three main steps in the treatment of COPD: prevention of the disease, treatment of its symptoms, progression and complications, and recovery of physical function through respiratory rehabilitation. Considerable advances have been produced in these three dimensions, but limitations have been detected, indicating areas for improvement. The most effective means to prevent the disease is smoking cessation. While there are moderately effective drugs to help individuals quit, no drugs are available to prevent relapses. Moreover, due to health policies, most patients with COPD do not receive drug treatment for smoking. The treatment of COPD and its complications is based on the use of bronchodilators, which improve symptoms and quality of life and, to a greater or lesser extent, prevent exacerbations. However, treatment aimed at the underlying pathogenic causes of the disease, which should be antiinflammatory treatment, remains an unresolved issue due to the discouraging results obtained with inhaled corticosteroids, which should always be used in combination with a bronchodilator. The development of new antiinflammatory agents, such as roflumilast, could improve the management of patients with the most severe disease and repeated exacerbations. Lastly, although respiratory rehabilitation is highly effective in helping patients recover their ability to exercise, few patients have access to this option. As with the treatment of smoking, there is a need to implement respiratory rehabilitation through simple and effective programs and with the support of the health administration.
journal_name
Arch Bronconeumoljournal_title
Archivos de bronconeumologiaauthors
de Lucas Ramos P,López Martín S,Rodríguez González-Moro JMdoi
10.1016/S0300-2896(10)70050-8subject
Has Abstractpub_date
2010-12-01 00:00:00pages
8-13eissn
0300-2896issn
1579-2129pii
S0300-2896(10)70050-8journal_volume
46 Suppl 10pub_type
杂志文章,评审abstract:OBJECTIVES:To analyze the results of thymectomy in our series of patients with myasthenia gravis (MG) and to study the influence of the most common prognostic factors. MATERIAL AND METHODS:Eighty MG patients over a period of 23 years underwent thymectomy consecutively in our hospital. Preoperative assessment included ...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(01)75045-4
更新日期:2001-04-01 00:00:00
abstract:INTRODUCTION:Thoracic trauma is often associated with polytrauma. Because mortality is high, the search for prognostic tools is useful. PATIENTS AND METHODS:A total of 108 patients with blunt thoracic trauma, 73 of whom had multiple injuries, were studied in an intensive care unit (ICU). The variables named as potenti...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVES:Although an association between uric acid (UA) levels and obstructive sleep apnea (OSA) has been reported, the effect of continuous positive airway pressure (CPAP) on this measure is yet unclear. We aimed to investigate the effect of CPAP therapy on serum UA levels in patients with OSA. METHODS:We conducted...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.arbres.2018.09.012
更新日期:2019-04-01 00:00:00
abstract::In 2008, the Spanish Society of Pulmonology (SEPAR) published the first guidelines in the world on the diagnosis and treatment of bronchiectasis. Almost 10 years later, considerable scientific advances have been made in both the treatment and the evaluation and diagnosis of this disease, and the original guidelines ha...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,实务指引
doi:10.1016/j.arbres.2017.07.015
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to assess changes in the acid-base equilibrium of pleural fluid during the first 2 hours after thoracentesis and to determine whether, as with arterial blood, it is important to keep the fluid on ice. PATIENTS AND METHODS:A prospective, descriptive, comparative study was performed i...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(06)60295-4
更新日期:2005-11-01 00:00:00
abstract::In both thromboembolic disease and pulmonary hypertension, 2010 has been a prodigious year for interesting publications. Some data have helped to elucidate the factors associated with a greater risk of thromboembolic disease, such as long journeys and certain polymorphisms. New recommendations on diagnosis have been m...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/S0300-2896(11)70003-5
更新日期:2011-01-01 00:00:00
abstract::Our aim was to describe our experience with outpatients requiring pleural biopsy. The first 100 patients with pleural exudate from whom at least one pleural biopsy specimen was taken on an outpatient basis at our hospital since January 1993. Clinical and radiological signs were recorded for all patients. We also analy...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)30566-4
更新日期:1997-09-01 00:00:00
abstract:OBJECTIVE:To analyze the network structure of collaboration between medical centers sharing authorship of scientific articles on smoking. MATERIAL AND METHODS:Articles reporting smoking research by authors from 2 or more Spanish medical centers between 1999 and the end of 2003 were identified through the Science Citat...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/s1579-2129(07)60089-5
更新日期:2007-07-01 00:00:00
abstract::Ever since Sullivan introduced nighttime nasal continuous pressure on the upper airway (CPAP) in 1981 it has been the standard treatment for sleep-hypopnea syndrome (SAHS). However, CPAP is carried out at great expense and is not tolerated by all patients. Moreover, its efficacy is dependent on the degree of complianc...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)30964-9
更新日期:1995-02-01 00:00:00
abstract:OBJECTIVES:To determine the number of smokers, their demographic characteristics, and the stages of change among patients visiting health care centers. PATIENTS AND METHODS:Descriptive cross-sectional study carried out at 7 primary health care centers in Health District 5 of the Autonomous Community of Valencia. RESU...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:2004-04-01 00:00:00
abstract::Several commonly prescribed drugs can cause acute non-cardiogenic pulmonary edema. A cause-effect relationship is usually difficult to establish because symptoms are not specific. We report a case of pulmonary edema induced by a common diuretic, hydrochlorothiazide. This complication can occur after a first dose of th...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(03)75329-0
更新日期:2003-02-01 00:00:00
abstract::The evaluation of the disabilities of patients with respiratory disease is regulated by the Spanish Ministry of Labor and Social Security, as are disabilities of any other type. We believe, however, that in respiratory pathologies this evaluation is especially complicated because, as they are chronic processes, they i...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/j.arbres.2011.12.005
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:To analyze the results of resection of lung metastases from colorectal adenocarcinoma in selected patients, evaluating type of resection, morbidity and mortality associated with the procedure, and overall actuarial survival rates after surgery. PATIENTS AND METHODS:Between 1988 and 1996, 811 patients were tr...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:1999-04-01 00:00:00
abstract::It has been suggested that human papillomavirus (HPV) could participate in the development of non-small-cell lung cancer (NSCLC). A higher HPV infection rate has been reported in the NSCLC samples from Asian non-smoker patients, with adenocarcinomas or responders to EGFR tyrosine kinase inhibitors (EGFR-TKI). We explo...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2012.04.003
更新日期:2013-02-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVE:Non-tuberculous mycobacteria (NTM) isolates are becoming more common. The main objective of our study was to establish the number and diversity of NTM species in our region and their distribution according to the source sample, age and gender of the patients, and to analyse clinically signifi...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2017.02.014
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVE:As the research undertaken to date on the efficacy of the new antibiotics in the treatment of exacerbations of chronic bronchitis has taken the form of trials designed to demonstrate equivalence, we have no data on the advantages associated with the use of these new drugs with greater bactericidal activity. O...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,meta分析,评审
doi:10.1016/s1579-2129(07)60016-0
更新日期:2007-01-01 00:00:00
abstract::Assessment of alpha 1-antitrypsin replacement therapy (AAT) for emphysema. Patient characteristics were analyzed along with the possible side effects of the treatment and its efficacy in maintaining appropriate AAT blood levels. Lung function changes were also studied. The treatment protocol began with 4 weekly intrav...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)30997-2
更新日期:1994-12-01 00:00:00
abstract:OBJECTIVE:To analyse the results obtained in the diagnosis and staging of lung cancer (LC) by a Lung Cancer Rapid Diagnosis Unit (LC-RDU) in which real-time endobronchial ultrasound-guided transbronchial needle aspiration (RT-EBUS guided-TBNA) is performed as part of the clinical evaluation of the patient prior to trea...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2010.07.005
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVE:Workers in shoe manufacturing have been reported to be at a greater relative risk for bronchogenic carcinoma. Given the implications for our practice setting, we carried out a study to a) clarify whether working in shoe manufacturing is a risk factor for lung cancer and b) detect histological differences betw...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(06)60426-6
更新日期:2005-04-01 00:00:00
abstract::Chronic obstructive pulmonary disease (COPD) and lung cancer (LC) are prevalent diseases and are a leading cause of morbidity and mortality worldwide. There is strong evidence to show that COPD is an independent risk factor for LC. Chronic inflammation plays a significant pathogenic role in COPD comorbidities, particu...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/j.arbres.2015.07.003
更新日期:2016-01-01 00:00:00
abstract:INTRODUCTION:Obesity is associated with 2 closely related respiratory diseases: obesity hypoventilation syndrome (OHS) and obstructive sleep apnea-hypopnea syndrome (OSAHS). It has been shown that noninvasive ventilation during sleep produces clinical and functional improvement in these patients. The long-term survival...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2014.02.015
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:To study the results of surgical treatment of pulmonary metastases in our department. PATIENTS AND METHODS:We retrospectively studied 44 patients undergoing surgery between 1986 and 1999 for complete resection of pulmonary metastases. Primary tumors had been eradicated, no metastasis to other organs was evid...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
abstract:INTRODUCTION AND AIMS:Chronic inflammation plays a major role in lung deterioration in cystic fibrosis (CF) patients and anti-inflammatory strategies have beneficial effects. To study the changes seen after a one-year course of low-dose dietary supplements with a mixture of fatty acids in adult patients with CF in chro...
journal_title:Archivos de bronconeumologia
pub_type: 临床试验,杂志文章
doi:10.1016/j.arbres.2009.11.001
更新日期:2010-02-01 00:00:00
abstract::Organizing pneumonia is a clinical and histological condition in which the onset is usually subacute with respiratory symptoms and pulmonary infiltrates. It may be unknown origin (cryptogenic) or associated with other illnesses, infectious diseases or drugs. We present a 60 year-old female patient with a previous hist...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2009.09.016
更新日期:2010-08-01 00:00:00
abstract::Ten cases of pulmonary mycetoma diagnosed in our service between 1985-1992 were retrospectively studied. Clinical methodology followed in the study is commented and the different therapeutic options are reviewed, so the literature concerning this process. The unspecificity of serum precipitins with Aspergillus is emph...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)31048-6
更新日期:1994-08-01 00:00:00
abstract::Chest ultrasound, a diagnostic technique used mainly by radiologists, is useful for managing pleural effusion. Sonography and computed tomography (CT) are complementary, although the former is more accessible to clinicians because it is safe and easy to use and because results are available quickly. We evaluated the u...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(03)75376-9
更新日期:2003-06-01 00:00:00
abstract::In lung transplantation, the presence of bronchogenic carcinoma in the native organ is uncommon, but doubtless affects patient survival, independently of the transplantation process itself. We describe 2 cases in which a primary tumor was found in the explanted lung--1 case of adenocarcinoma in a patient with pulmonar...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(07)60032-9
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVE:To analyze the reliability and validity of the short form of the generic quality of life scale (SF-36) when used with our asthmatic patients. METHODS:Two hundred nineteen adults with asthma of any etiology and without limits on sex, type or severity of asthma who were being treated at 10 health clinics (Madr...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(02)75139-9
更新日期:2002-01-01 00:00:00
abstract:INTRODUCTION:In 1977 silica was listed as a group 1 carcinogen (demonstrated in humans) by the International Agency for Research on Cancer. However, conflicting results from various studies have kept debate alive as to its carcinogenic capacity. The interest of this debate lies in the large number of workers exposed to...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(02)75291-5
更新日期:2002-12-01 00:00:00
abstract:BACKGROUND:The PLATINO baseline study, conducted from 2003-2005 in five Latin American cities (São Paulo, Mexico City, Montevideo, Santiago, Caracas), showed a high prevalence of chronic obstructive pulmonary disease (COPD). METHODS/DESIGN:A follow-up study was conducted in three out of the five centers (Montevideo, S...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,多中心研究
doi:10.1016/j.arbres.2013.07.014
更新日期:2014-01-01 00:00:00