Abstract：
:Nycthemeral changes in renal function have been known for a long time, but our knowledge about the underlying mechanisms is still far from complete. From a theoretical point of view, many physiological systems could be involved in turning the kidney from a sodium-excretory organ during daytime into a sodium-conserving organ during nighttime. Although blood pressure itself may regulate sodium output directly through pressure natriuresis, this mechanism can be unmasked only when other influences on the kidney can be eliminated. Hence, there is not enough evidence that pressure natriuresis governs cyclic variations in sodium output in the intact human being. Although the glomerular filtration rate follows a nocturnal variation pattern that is more or less in phase with the pattern of sodium excretion, the amplitudes of both differ so much that it is not likely that filtration alone can account for the changes in electrolyte output. The available data are compatible with tubular mechanisms, notably in the distal parts of the nephron. Recent molecular studies have identified several circadian gene products that may entrain the sodium excretory rhythm.
journal_name
Curr Hypertens Repjournal_title
Current hypertension reportsauthors
de Leeuw PWdoi
10.1007/s11906-011-0183-1subject
Has Abstractpub_date
2011-04-01 00:00:00pages
136-41issue
2eissn
1522-6417issn
1534-3111journal_volume
13pub_type
杂志文章,评审abstract：PURPOSE OF REVIEW:This is a review of available data on the effects of blood pressure and statins on cognition. RECENT FINDINGS:Recent randomized clinical trials have shown that intensive control of systolic blood pressure in older adults prevented the development of mild cognitive impairment (MCI) and the combined ef...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-019-0973-4
更新日期：2019-07-26 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-006-0013-z
更新日期：2006-05-01 00:00:00
abstract：:This paper critically addresses the issue of the "J-curve" paradox--the finding described in studies performed about 30 years ago indicating that treatment-induced systolic blood pressure values below 120 or 125 mm Hg and diastolic blood pressure values below 75 mm Hg are characterized by an increase, rather than a re...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-010-0121-7
更新日期：2010-08-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-009-0021-x
更新日期：2009-04-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-007-0076-5
更新日期：2007-11-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-013-0371-2
更新日期：2013-10-01 00:00:00
abstract：PURPOSE OF REVIEW:This meta-analysis and systematic review was conducted to evaluate the effect of probiotics on blood pressure, body mass index (BMI), and blood glucose changes in patients with hypertension. RECENT FINDINGS:We searched the PubMed, Cochrane, Embase, and ProQuest databases using a combination of MeSH a...
journal_title：Current hypertension reports
pub_type： 杂志文章,meta分析
doi：10.1007/s11906-020-01042-4
更新日期：2020-03-21 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-003-0005-1
更新日期：2003-02-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-020-01047-z
更新日期：2020-05-27 00:00:00
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journal_title：Current hypertension reports
pub_type： 临床试验,杂志文章,评审
doi：10.1007/s11906-000-0038-7
更新日期：2000-08-01 00:00:00
abstract：PURPOSE OF REVIEW:To review the most recent literature on current strategies for the treatment of hypertension associated with pediatric obesity. RECENT FINDINGS:Over the last three decades, childhood and adolescent overweight and obesity prevalence in the USA has continued to rise. Unsurprisingly but rather disturbin...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-019-0922-2
更新日期：2019-02-12 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-017-0750-1
更新日期：2017-07-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-008-0066-2
更新日期：2008-10-01 00:00:00
abstract：PURPOSE OF REVIEW:In chronic kidney disease (CKD), plasma uric acid levels are increased because of the decrease in glomerular filtration rate. However, in addition to CKD, hyperuricemia is frequently associated with a number of other conditions such as hypertension, type 2 diabetes, obesity, and heart failure, overwei...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-020-01116-3
更新日期：2020-10-31 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-999-0025-6
更新日期：1999-06-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-006-0054-3
更新日期：2006-06-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-013-0379-7
更新日期：2013-10-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-018-0821-y
更新日期：2018-03-19 00:00:00
abstract：:Investigations using chronic blood pressure (BP) radiotelemetry in conscious animals have provided substantial insights into the pathophysiology of hypertensive renal damage. Normal renal autoregulation protects the renal microvasculature from significant injury in most patients with primary hypertension, unless BP ex...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-004-0091-8
更新日期：2004-04-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-016-0663-4
更新日期：2016-07-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-014-0502-4
更新日期：2014-12-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,meta分析
doi：10.1007/s11906-003-0044-7
更新日期：2003-08-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-006-0041-8
更新日期：2006-04-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-008-0075-1
更新日期：2008-10-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-012-0309-0
更新日期：2012-12-01 00:00:00
abstract：:Antiplatelet agents represent a cornerstone in the management of patients at increased cardiovascular risk. Essential hypertension is considered a major public health problem leading to increased cardiovascular morbidity and mortality. The majority of patients with essential hypertension exhibit also additional cardio...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-015-0536-2
更新日期：2015-04-01 00:00:00
abstract：PURPOSE OF THE REVIEW:It is well-established that the age-related increase in blood pressure is augmented after menopause. Yet, the prevalence of hypertension is enhanced in low birth weight women relative to normal birth weight counterparts by 60 years of age suggesting that adverse influences during fetal life height...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-017-0712-7
更新日期：2017-02-01 00:00:00
abstract：:Hypertension is a preventable condition, and the outcomes of clinical trials have established that its treatment reduces cardiovascular morbidity and mortality. Although awareness about the disease has improved in the past two decades, the reality is that many people remain untreated or not adequately controlled. The ...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-001-0007-9
更新日期：2001-12-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-017-0763-9
更新日期：2017-08-01 00:00:00
abstract：:Young and middle-aged adults (ages ≤50 years) are increasingly prone to stroke, kidney disease, and worsening cardiovascular disease (CVD) mortality. An alarming increase in the prevalence of high blood pressure (BP) may underlie the adverse trend. However, there is often uncertainty in BP management for young and mid...
journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-016-0686-x
更新日期：2016-11-01 00:00:00
