Albuminuria: what can we expect from the determination of nonimmunoreactive albumin?

abstract：:The discovery of beneficial neuroprotective effects of the angiotensin converting enzyme 2-angiotensin-(1-7)-Mas axis [ACE2-Ang-(1-7)-Mas] in ischemic and hemorrhagic stroke has spurred interest in a more complete characterization of its mechanisms of action. Here, we summarize findings that describe the protective ro...

journal_title：Current hypertension reports

authors： Bennion DM,Haltigan E,Regenhardt RW,Steckelings UM,Sumners C

更新日期：2015-02-01 00:00:00

abstract：:Women with chronic hypertension and pregnancy-induced hypertension are at substantial risk for developing pre-eclampsia/eclampsia, a disease with high fetomaternal morbidity and mortality. However, the etiology of this disease is still unknown. In this article, recent concepts on the pathophysiology of pre-eclampsia, ...

journal_title：Current hypertension reports

authors： Kashiwagi M,Zimmermann R,Beinder E

更新日期：2003-12-01 00:00:00

abstract：:Heart failure has emerged as one of the most important diseases of the past century. The understanding and treatment of heart failure has evolved significantly over the years. As we move further into the era of device therapy, attention has turned to the idea of sympathetic nervous system modulation through renal dene...

journal_title：Current hypertension reports

authors： Fong MW,Shavelle D,Weaver FA,Nadim MK

更新日期：2015-03-01 00:00:00

abstract：:Inflammation plays an important role in the pathogenesis of hypertension. Innate and adaptive immune response may contribute to this process. The mechanisms implicating immune response in hypertension are still elusive. To date, the evidence originates in three major areas of data: cytokine production, central nervous...

journal_title：Current hypertension reports

authors： Leibowitz A,Schiffrin EL

更新日期：2011-12-01 00:00:00

abstract：:Nitric oxide is involved in the regulation of resting vascular tone, adaptation of blood flow to metabolic demand of tissue, and adaptation of vessel diameter to volume of inflow, ie, flow-mediated dilation. Arterial hypertension is associated with an increased vascular tone of resistance vessels, a reduced compliance...

journal_title：Current hypertension reports

authors： Kelm M

更新日期：2003-02-01 00:00:00

abstract：:Vascular changes associated with elevated blood pressure may precede the clinical diagnosis of hypertension. Even after the diagnosis is made, associated coronary heart disease and renal disease continue to progress, despite adequate blood pressure control. Early treatment of blood pressure may reduce the incidence of...

journal_title：Current hypertension reports

authors： Nesbitt SD,Julius S

更新日期：2000-08-01 00:00:00

abstract：:The impaired capacity of the kidney to excrete sodium plays an essential role in the development of hypertension. Adrenal corticosteroids control renal handling of sodium by regulating tubular sodium reabsorption in the distal nephron where both mineralocorticoid receptors (MR) and glucocorticoid receptors are express...

journal_title：Current hypertension reports

authors： Ayuzawa N,Fujita T

更新日期：2015-06-01 00:00:00

abstract：:Angiotensin II is the most active hormone of the renin-angiotensin system. In humans, two angiotensin receptors have been identified: AT(1) and AT(2). In adults, most of the effects of angiotensin II are mediated by the AT(1) receptor; the function of the AT(2) receptor is not yet well established. Angiotensin II has ...

journal_title：Current hypertension reports

authors： Siragy HM,Bedigian M

更新日期：1999-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Renal sympathetic denervation (RDN) as treatment option for hypertension has a strong rationale; however, variable effects on blood pressure (BP) have been reported ranging from non-response to marked reductions in BP. The absence of a procedural end point for RDN is one of the potential factors assoc...

journal_title：Current hypertension reports

authors： Hoogerwaard AF,de Jong MR,Elvan A

更新日期：2018-03-19 00:00:00

abstract：:In the quest for "evidence-based" medicine, an accepted hierarchy of evidence has been proposed. This hierarchy places in vitro studies and animal data at the base, and puts systematic reviews, meta-analyses, and randomized controlled trials at the pinnacle. However, when clinical medicine faces questions that have no...

journal_title：Current hypertension reports

authors： Hawkins RG

更新日期：2006-06-01 00:00:00

abstract：:The renin-angiotensin system (RAS) plays an important role in the initiation and progression of tissue injuries in the cardiovascular and nervous systems. The detrimental actions of the AT1 receptor (AT1R) in hypertension and vascular injury, myocardial infarction and brain ischemia are well established. In the past t...

journal_title：Current hypertension reports

authors： Namsolleck P,Recarti C,Foulquier S,Steckelings UM,Unger T

更新日期：2014-02-01 00:00:00

abstract：:The treatment of hypertension is proven to reduce cardiovascular and renal risk. Combination drug therapy is becoming recognized as a necessity in most patients with hypertension and kidney disease. Allegations about the safe use of calcium antagonists in patients with kidney disease have led to questions and confusio...

journal_title：Current hypertension reports

authors： Tobe S,Epstein M

更新日期：2002-06-01 00:00:00

abstract：:Investigations using chronic blood pressure (BP) radiotelemetry in conscious animals have provided substantial insights into the pathophysiology of hypertensive renal damage. Normal renal autoregulation protects the renal microvasculature from significant injury in most patients with primary hypertension, unless BP ex...

journal_title：Current hypertension reports

authors： Griffin KA,Bidani AK

更新日期：2004-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This study aims to systematically review existing evidence on the effectiveness of mobile health technology (mHealth) interventions in addressing medication adherence among people with hypertension. RECENT FINDINGS:Twenty-one studies of mHealth interventions were included in the final review after sy...

journal_title：Current hypertension reports

authors： Xiong S,Berkhouse H,Schooler M,Pu W,Sun A,Gong E,Yan LL

更新日期：2018-08-07 00:00:00

abstract：:The central nervous system plays a key role in the regulation of cardiovascular function, and alterations in the central neural mechanisms that control blood pressure may underlie the vast majority of cases of primary hypertension. The well-studied baroreceptor reflex powerfully regulates arterial pressure, though its...

journal_title：Current hypertension reports

authors： Sved AF,Ito S,Sved JC

更新日期：2003-06-01 00:00:00

abstract：:Administering relaxin to conscious rats and humans elicits systemic and renal vasodilation. The molecular mechanisms vary according to the duration of relaxin exposure-so-called "rapid" (within minutes) or "sustained" (hours to days) vasodilatory responses-both being endothelium-dependent. Rapid responses are mediated...

journal_title：Current hypertension reports

authors： Conrad KP,Shroff SG

更新日期：2011-12-01 00:00:00

abstract：:The metabolic syndrome associates metabolic abnormalities such as insulin resistance and dyslipidemia with increased waist circumference and hypertension. It is a major public health concern, as its prevalence could soon reach 30% to 50% in developed countries. Aldosterone, a mineralocorticoid hormone classically invo...

journal_title：Current hypertension reports

authors： Briet M,Schiffrin EL

更新日期：2011-04-01 00:00:00

abstract：:Hypertension (especially systolic hypertension) is very common in older persons. Systolic hypertension occurs because large conduit arteries become stiffer with age. Strong evidence from randomized trials suggests that treating systolic blood pressures initially higher than 160 mm Hg is extremely beneficial, and a rec...

journal_title：Current hypertension reports

authors： Hyman DJ,Taffet GE

更新日期：2009-10-01 00:00:00

abstract：:Hypertension is very common in patients with chronic renal failure and contributes to cardiovascular morbidity and mortality. Several mechanisms may contribute to hypertension in these patients, but recently a large body of evidence supports the notion that activation of the sympathetic nervous system (SNS) may play a...

journal_title：Current hypertension reports

authors： Campese VM,Krol E

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes the latest science on hypertensive encephalopathy and posterior reversible encephalopathy syndrome (PRES). We review the epidemiology and pathophysiology of these overlapping syndromes and discuss best practices for diagnosis and management. RECENT FINDINGS:Diagnosis of hyperte...

journal_title：Current hypertension reports

authors： Miller JB,Suchdev K,Jayaprakash N,Hrabec D,Sood A,Sharma S,Levy PD

更新日期：2018-02-26 00:00:00

abstract：:Cardiovascular disease disproportionately affects minority populations, in part because of multiple sociocultural factors that directly affect compliance with antihypertensive medication regimens. Compliance is a complex health behavior determined by a variety of socioeconomic, individual, familial, and cultural facto...

journal_title：Current hypertension reports

authors： Betancourt JR,Carrillo JE,Green AR

更新日期：1999-12-01 00:00:00

abstract：:Na+,K+-ATPase distributes ions between the intracellular and extracellular space and is responsible for total-body sodium homeostasis. The activity of this ion pump is regulated by catecholamines and peptide hormones; by the ligand of Na+,K+-ATPase, ouabain; and by direct interaction with cytoskeleton proteins. This r...

journal_title：Current hypertension reports

authors： Aperia A

更新日期：2001-04-01 00:00:00

abstract：:Chronic kidney disease is a major public health problem worldwide: it is estimated that in the general population, 1 person in 10 has some degree of renal damage. Adequate blood pressure control represents the mainstay of treatment, to delay deterioration of renal function and prevent cardiovascular complications. Cur...

journal_title：Current hypertension reports

authors： Leoncini G,Viazzi F,Pontremoli R

更新日期：2010-10-01 00:00:00

abstract：:Young hypertensive adults demonstrate decreased performance on neurocognitive testing compared with that of normotensive controls. There is emerging, preliminary evidence that children with hypertension also manifest cognitive differences when compared to normotensive controls. These preliminary studies consist mostly...

journal_title：Current hypertension reports

authors： Lande MB,Kupferman JC

更新日期：2015-01-01 00:00:00

abstract：:This paper reviews findings on the relationship between blood pressure control and the progression of renal disease. Experimental studies demonstrate a correlation between systemic blood pressure and histologic glomerular injury and the delay in progression of renal disease with antihypertensive therapy, particularly ...

journal_title：Current hypertension reports

authors： Dworkin LD,Shemin DG

更新日期：1999-10-01 00:00:00

abstract：:The publication of the Antihypertensive and Lipid-lowering Treatment to Prevent Heart Attack Trial (ALLHAT) results, when used in conjunction with a new meta-analysis, provides hypertension research with a watershed. Data demonstrate clearly that lowering blood pressure is the most important aspect of hypertension man...

journal_title：Current hypertension reports

authors： Wang JG,Staessen JA,Heagerty AM

更新日期：2003-08-01 00:00:00

abstract：:Individuals with hypertension need to stay on therapy with antihypertensive medication to obtain the full benefits of blood pressure reduction. There are important differences in tolerability across antihypertensive drug classes, and these differences influence the extent to which patients are willing to continue taki...

journal_title：Current hypertension reports

authors： Gerth WC

更新日期：2002-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To estimate the impact of the 2017 American College of Cardiology/American Heart Association (ACC/AHA) guidelines for high blood pressure (BP) on the next hypertension guidelines in Asia. RECENT FINDINGS:The 2017 ACC/AHA guidelines for high BP in adults changed the diagnostic threshold and the manage...

journal_title：Current hypertension reports

authors： Nakagawa N,Hasebe N

更新日期：2019-01-10 00:00:00

abstract：PURPOSE OF REVIEW:Review the renal nerve anatomy and physiology basics and explore the concept of global vs. selective renal denervation (RDN) to uncover some of the fundamental limitations of non-targeted renal nerve ablation and the potential superiority of selective RDN. RECENT FINDINGS:Recent trials testing the ef...

journal_title：Current hypertension reports

authors： Fudim M,Sobotka AA,Yin YH,Wang JW,Levin H,Esler M,Wang J,Sobotka PA

更新日期：2018-05-01 00:00:00

abstract：:The kidneys play a central role in the long-term regulation of blood pressure and in the pathogenesis of hypertension. A common defect that has been found in all forms of hypertension examined to date is a hypertensive shift in the pressure-natriuresis relationship. A major objective of this brief review is to highlig...

journal_title：Current hypertension reports

authors： Granger JP,Abram S,Stec D,Chandler D,LaMarca B

更新日期：2006-08-01 00:00:00