Autogenous transcriptional regulation of the regA gene, encoding an AraC-Like, essential virulence regulator in Citrobacter rodentium.

Abstract:

:We identified several promoters responsible for the expression of regA, which encodes a global virulence regulator in Citrobacter rodentium. Expression of some of the promoters was strongly autoactivated by RegA in conjunction with bicarbonate. Biochemical and mutational analyses were used to determine the consensus sequence of the RegA-binding sites.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Tan A,Yang J,Tauschek M,Praszkier J,Robins-Browne RM

doi

10.1128/JB.01224-10

subject

Has Abstract

pub_date

2011-04-01 00:00:00

pages

1777-82

issue

7

eissn

0021-9193

issn

1098-5530

pii

JB.01224-10

journal_volume

193

pub_type

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