Endometrial polyps affect uterine receptivity.

Abstract:

:This case-control study evaluated the effect of hysteroscopically identified endometrial polyps on endometrium by means of HOXA10 and HOXA11, known molecular markers of endometrial receptivity. Uteri with endometrial polyps demonstrated a marked decrease in HOXA10 and HOXA11 messenger RNA levels, which may impair implantation. These findings suggest a molecular mechanism to support the clinical findings of diminished pregnancy rates in women with endometrial polyps.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Rackow BW,Jorgensen E,Taylor HS

doi

10.1016/j.fertnstert.2010.12.034

subject

Has Abstract

pub_date

2011-06-30 00:00:00

pages

2690-2

issue

8

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(10)02977-8

journal_volume

95

pub_type

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