The patient with Turner syndrome: puberty and medical management concerns.

Abstract:

:Turner syndrome (TS), which affects approximately 1 in 2,500 live-born females, is characterized by loss or structural anomalies of an X chromosome. Clinical features vary among patients; multiple organ systems can be affected. Endocrinologists are involved in the management of short stature, delayed puberty, and infertility. Endocrine therapies can include growth hormone, estrogen, and progestogen to promote linear growth and pubertal development. The duration of estrogen and progestogen treatment hormone treatment (HT) is generally more than 40 years. No one standard HT is suitable for all women, so general guidelines are provided to induce pubertal development. Additional considerations regarding HT choice include thrombotic risk and disorders associated with thrombophilia. Involvement of cardiologists is important because approximately 50% of patients with TS have congenital structural cardiac anomalies linked to an increased risk for aortic dissection and rupture. Oocyte donation offers the chance to carry a pregnancy, but accumulating information has highlighted the potential dangers associated with pregnancy. Advances in the care of infants, girls, and women with TS have been achieved; management involves coordinated care from a multidisciplinary team including endocrinologists, cardiologists, geneticists, otolaryngologists, behavioral health experts, nurse educators, and social workers.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Gonzalez L,Witchel SF

doi

10.1016/j.fertnstert.2012.07.1104

subject

Has Abstract

pub_date

2012-10-01 00:00:00

pages

780-6

issue

4

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(12)01840-7

journal_volume

98

pub_type

杂志文章,评审
  • Does stimulation with human gonadotropins and gonadotropin-releasing hormone agonist enhance and accelerate the developmental capacity of oocytes in human ovarian tissue xenografted into severe combined immunodeficient mice?

    abstract:OBJECTIVE:To assess the capacity of human frozen-thawed ovarian follicles matured in xenografts to form metaphase II (MII) oocytes after xenotransplantation and exogenous stimulation. DESIGN:Prospective controlled animal study. SETTING:University hospital gynecology research unit. PATIENT(S):Ovarian fragments were o...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2014.01.038

    authors: Lotz L,Schneider H,Hackl J,Wachter D,Hoffmann I,Jurgons R,Beckmann MW,Dittrich R

    更新日期:2014-05-01 00:00:00

  • An intrauterine insemination-ready cryopreservation method compared with sperm recovery after conventional freezing and post-thaw processing.

    abstract:OBJECTIVE:To test a sucrose-glycerol cryoprotectant for IUI-ready sperm preparation. DESIGN:Semen aliquots from normozoospermic donors either were subjected to conventional semen freezing (TES and Tris yolk buffer in 7.4% final glycerol) with post-thaw processing or were preprocessed and frozen in HEPES-buffered human...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(97)81491-4

    authors: Larson JM,McKinney KA,Mixon BA,Burry KA,Wolf DP

    更新日期:1997-07-01 00:00:00

  • Presence of soluble b-type cytochrome in human seminal fluid.

    abstract::In 1951 it was shown that human spermatozoa contained cytochromes a, b, and c. It was noted that the cytochromes were confined to the sperm and were not found in seminal fluid. More recently we have observed in seminal plasma a soluble component that has a typical spectrum of a reduced cytochrome b, but can be disting...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:

    authors: Trifunac NP,Bernstein GS

    更新日期:1981-03-01 00:00:00

  • Comparison of different sources of platelet-rich plasma as treatment option for infertility-causing endometrial pathologies.

    abstract:OBJECTIVE:To study the effect of human plasma from different sources, namely, umbilical cord blood and adult blood platelet-rich plasma (PRP), on the regeneration of endometrial damage. DESIGN:Composition analysis, in vitro approaches, and a preclinical murine model using plasma to promote endometrial regeneration. S...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2020.07.053

    authors: de Miguel-Gómez L,López-Martínez S,Campo H,Francés-Herrero E,Faus A,Díaz A,Pellicer A,Domínguez F,Cervelló I

    更新日期:2020-08-24 00:00:00

  • A polymorphism of the interleukin-1beta gene and idiopathic recurrent miscarriage.

    abstract:OBJECTIVE:Proinflammatory cytokines have been described to be involved in the pathogenesis of idiopathic recurrent miscarriage (IRM). We investigated the association between IRM and a polymorphism in exon 5 of the interleukin-1beta gene (IL1B) and interleukin-1beta (IL-1beta) serum levels. DESIGN:Case control study. ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(01)01914-8

    authors: Hefler LA,Tempfer CB,Unfried G,Schneeberger C,Lessl K,Nagele F,Huber JC

    更新日期:2001-08-01 00:00:00

  • Guidelines for development of an emergency plan for in vitro fertilization programs.

    abstract::All in vitro fertilization (IVF) programs and clinics should have a plan to protect fresh and cryopreserved human tissue (embryos, oocytes, sperm) and to provide for continuation of patient care in the event of an emergency or natural disaster. ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2008.08.063

    authors: Practice Committee of Society for Assisted Reproductive Technology.,Practice Committee of American Society for Reproductive Medicine.

    更新日期:2008-11-01 00:00:00

  • Decreasing serum levels of sex hormone-binding globulin around the menopause and temporary relation to changing levels of ovarian steroids, as demonstrated in a longitudinal study.

    abstract::Blood samples collected longitudinally in 17 women over a period of 3 years, starting 11/2 years before the menopause, were assessed for sex hormone-binding globulin (SHBG), 17 beta-estradiol (E2), progesterone, and total testosterone. A slight (7.2%) decrease in mean SHBG from 4.25 +/- 1.67 (standard deviation) mg/l ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)60609-x

    authors: Gershagen S,Doeberl A,Jeppsson S,Rannevik G

    更新日期:1989-04-01 00:00:00

  • Clomiphene citrate intrauterine insemination (IUI) before gonadotropin IUI affects the pregnancy rate and the rate of high-order multiple pregnancies.

    abstract:OBJECTIVE:To determine if previous treatment with clomiphene citrate intrauterine insemination (CC-IUI) affects pregnancy and high-order multiple pregnancy (HOMP) rates in subsequent hMG-IUI or FSH-IUI cycles. DESIGN:Retrospective cohort study. SETTING:Private infertility clinic. PATIENT(S):Five hundred fifty-one pa...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2003.07.031

    authors: Dickey RP,Taylor SN,Lu PY,Sartor BM,Pyrzak R

    更新日期:2004-03-01 00:00:00

  • Human serum and follicular fluid stimulate hyperactivation of human spermatozoa after preincubation.

    abstract:OBJECTIVE:To test the effects of steroid-containing media such as follicular fluid (FF) and serum and of steroid-free but human protein-rich medium on hyperactivation (HA) of human spermatozoa with and without a preincubation period. DESIGN:Analysis of HA using a computer-aided sperm analysis system. SETTING:Academic...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)57191-x

    authors: Kulin S,Bastiaans BA,Hollanders HM,Janssen HJ,Goverde HJ

    更新日期:1994-12-01 00:00:00

  • Hyperprolactinemic male infertility.

    abstract::Serum prolactin was studied in 25 fertile and 127 infertile men. The latter included 91 oligospermic, 27 azoospermic, and 9 hypogonadotropic hypogonadal men. The mean prolactin level in all three groups of infertile men was significantly above that of the fertile group. There was no correlation among serum levels of f...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)42259-4

    authors: Segal S,Polishuk WZ,Ben-David M

    更新日期:1976-12-01 00:00:00

  • Initial evaluation of a convection counter streaming galvanization technique of sex separation of human spermatozoa.

    abstract::A new method for separating X and Y human spermatozoa called convection counter streaming galvanization was evaluated. The method was independently performed by this semenology laboratory with the use of the special separation equipment and extending media provided by its developer, Dr. Bhairab C. Bhattacharya. The me...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:

    authors: Daniell JF,Herbert CM,Repp J,Torbit CA,Wentz AC

    更新日期:1982-08-01 00:00:00

  • Blastocyst development in single medium with or without renewal on day 3: a prospective cohort study on sibling donor oocytes in a time-lapse incubator.

    abstract:OBJECTIVE:To evaluate the efficiency of using a continuous (one-step) protocol with a single medium for the culture of human embryos in a time-lapse incubator (TLI). DESIGN:Prospective cohort study on sibling donor oocytes. SETTING:University-affiliated in vitro fertilization (IVF) center. PATIENT(S):Embryos from 59...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.fertnstert.2015.11.038

    authors: Costa-Borges N,Bellés M,Meseguer M,Galliano D,Ballesteros A,Calderón G

    更新日期:2016-03-01 00:00:00

  • An effective "water injection"-assisted method for excision of ovarian endometrioma by laparoscopy.

    abstract:OBJECTIVE:To introduce an effective approach for excision of ovarian endometrioma by "water injection"-assisted laparoscopy treatment. DESIGN:Step-by-step video explanation of the surgical procedure with still pictures and surgical video clips to demonstrate the detailed technique, approved by the Shengjing Hospital o...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2019.05.014

    authors: Zhang NN,Sun TS,Yang Q

    更新日期:2019-09-01 00:00:00

  • Slow excretion of exogenous human chorionic gonadotropin simulating repeated pregnancies and pregnancy losses.

    abstract::We report a patient undergoing hMG-induced superovulation who demonstrated delayed excretion of hCG, originally believed to be because of successive biochemical pregnancies. However, sequential hCG titers after administration of exogenous hCG demonstrated a longer than normal half-life for the excretion of hCG in this...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)54618-4

    authors: Maier DB,Metzger DA

    更新日期:1991-10-01 00:00:00

  • Ultrarapid cryopreservation of human embryos: experience with 1,582 embryos.

    abstract:OBJECTIVES:To demonstrate the effectiveness of ultrarapid cryopreservation in human embryos. DESIGN:Retrospective study. SETTING:An IVF unit of a medical center. PATIENT(S):All cases received ultrarapid freezing (URF) of embryos and frozen embryo transfer. INTERVENTION(S):Embryos were placed in phosphate-buffered s...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(99)00257-5

    authors: Hsieh YY,Tsai HD,Chang CC,Chang CC,Lo HY,Lai AC

    更新日期:1999-08-01 00:00:00

  • Neodymium: YAG laser hysteroscopy in large submucous fibroids.

    abstract::The preoperative use of a potent, subcutaneously injected gonadotropin-releasing hormone agonist (GnRH-a) was evaluated in a series of 60 women with large submucosal fibroids. Myomectomy by hysteroscopy and Nd:YAG laser was easily performed. In 12 cases, the largest portion of the myoma was not inside the uterine cavi...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)53994-6

    authors: Donnez J,Gillerot S,Bourgonjon D,Clerckx F,Nisolle M

    更新日期:1990-12-01 00:00:00

  • Relationship of the individual uterine size and the endometrial thickness in stimulated cycles.

    abstract::At present there is no agreement regarding the usefulness of monitoring the endometrial thickness in stimulated cycles. We tested prospectively the hypothesis of a linear relationship of the given individual uterine size and the endometrial thickness in stimulated cycles using a 240 degrees transvaginal sector scanner...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)56716-8

    authors: Strohmer H,Obruca A,Radner KM,Feichtinger W

    更新日期:1994-05-01 00:00:00

  • Developmental potential of fully intact and partially damaged cryopreserved embryos after laser-assisted removal of necrotic blastomeres and post-thaw culture selection.

    abstract:OBJECTIVE:Partially damaged frozen and thawed embryos are currently considered to have a lower viability than intact ones. This study was undertaken to compare the performance of intact frozen and thawed embryos with that of partially damaged embryos after removal of the necrotic blastomeres. DESIGN:Observational clin...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2005.04.038

    authors: Rienzi L,Ubaldi F,Iacobelli M,Minasi MG,Romano S,Ferrero S,Sapienza F,Baroni E,Tesarik J,Greco E

    更新日期:2005-10-01 00:00:00

  • Tamoxifen citrate therapy in male infertility.

    abstract::A prospective, randomized, double-blind study with crossover, using tamoxifen (TAM) (Nolvadex, ici Pharma, Missisauga, Canada) 20 mg/day and placebo (p) for 6 months each, was conducted in 16 infertile men with idiopathic oligozoospermia. Baseline sperm count was 17.092 +/- 3.09 (10(6)/ml). Hormonal profile was perfor...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0015-0282(16)59299-1

    authors: AinMelk Y,Belisle S,Carmel M,Jean-Pierre T

    更新日期:1987-07-01 00:00:00

  • Follicle-stimulating hormone receptor gene mutations are rare in Japanese women with premature ovarian failure and polycystic ovary syndrome.

    abstract:OBJECTIVE:To determine whether the known inactivating FSH receptor gene mutations are present in Japanese women with secondary amenorrhea because of premature ovarian failure (POF) and polycystic ovary syndrome (PCOS). DESIGN:Clinical and molecular studies. SETTING:An outpatient clinic in a university hospital. PATI...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(00)01673-3

    authors: Takakura K,Takebayashi K,Wang HQ,Kimura F,Kasahara K,Noda Y

    更新日期:2001-01-01 00:00:00

  • Use of phenazopyridine for reducing discomfort during embryo transfer.

    abstract:OBJECTIVE:The embryo transfer is a critical part of in vitro fertilization. When performed under abdominal ultrasound guidance, the embryo transfer procedure requires a full bladder. Patients often state that the discomfort of the distended bladder causes more pain than the actual transfer procedure. Phenazopyridine HC...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.fertnstert.2006.08.097

    authors: Frishman GN,Allsworth JE,Gannon JB,Wright KP

    更新日期:2007-05-01 00:00:00

  • Expanded carrier screening: what the reproductive endocrinologist needs to know.

    abstract::Expanded carrier screening refers to identification of carriers of single-gene disorders outside of traditional screening guidelines. New genetic testing technologies allow for such screening at costs that are comparable to single-gene testing. There is a high degree of variability among genetic testing laboratories a...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/j.fertnstert.2017.11.030

    authors: Dungan J

    更新日期:2018-02-01 00:00:00

  • Live birth after orthotopic grafting of autologous cryopreserved ovarian tissue and spontaneous conception in Italy.

    abstract:OBJECTIVE:To describe a live birth obtained in Italy after autologous orthotopic transplantation of cryopreserved ovarian cortical tissue. DESIGN:Case report. SETTING:University department of gynecology and obstetrics, reproductive medicine and IVF unit. PATIENT(S):A 29-year-old patient affected by β-thalassemia (in...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2012.09.029

    authors: Revelli A,Marchino G,Dolfin E,Molinari E,Delle Piane L,Salvagno F,Benedetto C

    更新日期:2013-01-01 00:00:00

  • A randomized comparison of vaginal misoprostol and dinoprostone for cervical priming in nulliparous women before operative hysteroscopy.

    abstract:OBJECTIVE:To compare the efficacy and side effects of vaginal misoprostol with dinoprostone for cervical priming before operative hysteroscopy and to assess the cervicouterine complications related to cervical dilatation and hysteroscopic surgery. DESIGN:A prospective randomized study. SETTING:Tertiary university hos...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.fertnstert.2006.03.039

    authors: Preutthipan S,Herabutya Y

    更新日期:2006-10-01 00:00:00

  • Effects of ovarian endometrioma on embryo quality.

    abstract::The proportions of good, fair, and poor embryos in 13 women with bilateral endometriomas were compared with those of 39 women without endometriomas and were found to be similar (47.2% vs. 41.1%, 28.3% vs. 32.8%, and 24.3% vs. 26.0%, respectively). Therefore, it appears that the presence of bilateral endometriomas duri...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2011.03.002

    authors: Reinblatt SL,Ishai L,Shehata F,Son WY,Tulandi T,Almog B

    更新日期:2011-06-30 00:00:00

  • Transforming growth factor (TGF)-beta1-induced human endometrial stromal cell decidualization through extracellular signal-regulated kinase and Smad activation in vitro: peroxisome proliferator-activated receptor gamma acts as a negative regulator of TGF-

    abstract:OBJECTIVE:To investigate the effect of transforming growth factor (TGF)-beta1 on the extracellular signal-regulated kinase (ERK) and Smad pathway and the role of peroxisome proliferator-activated receptor (PPAR)-gamma in cultured human endometrial stromal cells. DESIGN:Experimental study. SETTING:Infertility center o...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2007.09.010

    authors: Chang HJ,Lee JH,Hwang KJ,Kim MR,Chang KH,Park DW,Min CK

    更新日期:2008-10-01 00:00:00

  • Misconduct in third-party assisted reproduction: a committee opinion.

    abstract::Physicians who are told or discover information that would be material to another party's participation in an assisted reproductive technology (ART) arrangement (such as lawyer's, donor's, gestational carrier's, or intended parent's) should encourage disclosure to that party. In some instances, it is ethically and leg...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/j.fertnstert.2013.11.007

    authors: Ethics Committee of the American Society for Reproductive Medicine.

    更新日期:2014-01-01 00:00:00

  • Spontaneous conception after a successful attempt at in vitro fertilization/intracytoplasmic sperm injection.

    abstract:OBJECTIVE:To determine the incidence of spontaneous pregnancy in women who were not actively undergoing therapy after a successful attempt at IVF/intracytoplasmic sperm injection and to characterize its pattern of occurrence. DESIGN:Retrospective postal questionnaire. SETTING:An assisted reproduction unit at a univer...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(99)00609-3

    authors: Hennelly B,Harrison RF,Kelly J,Jacob S,Barrett T

    更新日期:2000-04-01 00:00:00

  • Assisted hatching and intracytoplasmic sperm injection are not associated with improved outcomes in assisted reproduction cycles for diminished ovarian reserve: an analysis of cycles in the United States from 2004 to 2011.

    abstract:OBJECTIVE:To investigate the impact of intracytoplasmic sperm injection (ICSI) and assisted hatching (AH) on assisted reproductive technology (ART) outcomes in initial cycles with diminished ovarian reserve (DOR) as the primary diagnosis. DESIGN:Retrospective cohort study of cycles from the Society for Assisted Reprod...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2014.06.043

    authors: Butts SF,Owen C,Mainigi M,Senapati S,Seifer DB,Dokras A

    更新日期:2014-10-01 00:00:00

  • Effect of excess dietary methionine on rat pregnancy: influence on ovarian delta5-3beta-hydroxysteroid dehydrogenase activity.

    abstract::The addition of 4% dl-methionine to a diet of 18% or 12% casein reduced pregnancy maintenance in the rat from 100% to 48% and 5%, respectively. Fetal weight was subnormal. The major influence of methionine was not due to reduced food intake as determined by pair-fed controls but was related to reduced ovarian function...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)42563-x

    authors: Chandrashekar V,Leathem JH

    更新日期:1977-05-01 00:00:00