Abstract:
OBJECTIVE:To determine the incidence of spontaneous pregnancy in women who were not actively undergoing therapy after a successful attempt at IVF/intracytoplasmic sperm injection and to characterize its pattern of occurrence. DESIGN:Retrospective postal questionnaire. SETTING:An assisted reproduction unit at a university-based teaching hospital. PATIENT(S):Five hundred thirteen replies were received from 530 questionnaires mailed. INTERVENTION(S):None. MAIN OUTCOME MEASURE(S):Spontaneous pregnancy. Women who did and did not conceive spontaneously after successful IVF treatment were compared in terms of their age, duration of infertility, previous reproductive history, and indication for treatment at the time of assisted reproduction. RESULT(S):The rate of spontaneous conception among the survey respondents was 20.7%. Younger women (=34 years of age) had a higher rate of spontaneous conception, as did those with a shorter duration of infertility. Women with unexplained infertility and endometriosis also were more likely to conceive. Few of those who had undergone intracytoplasmic sperm injection conceived, whereas 21.6% of those whose partners had had sperm quality sufficient for IVF later conceived spontaneously. CONCLUSION(S):The chances of spontaneous conception after successful ART therapy are significant in some groups of patients. This has implications for the practice of assisted reproduction and the obstetric care of patients who conceive with treatment. Contraceptive advice may need to be provided to couples who undergo IVF/intracytoplasmic sperm injection.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Hennelly B,Harrison RF,Kelly J,Jacob S,Barrett Tdoi
10.1016/s0015-0282(99)00609-3keywords:
subject
Has Abstractpub_date
2000-04-01 00:00:00pages
774-8issue
4eissn
0015-0282issn
1556-5653pii
S0015-0282(99)00609-3journal_volume
73pub_type
杂志文章abstract::The outcome of a series of pre-embryo transfers to 31 women with ovarian failure is described. Twenty six fertile women functioned as nonanonymous donors, providing oocytes for in vitro fertilization after undergoing controlled ovarian hyperstimulation and transvaginal ultrasound directed oocyte aspiration. Recipients...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)54055-2
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:To estimate the incidence of endometriosis in an operative cohort of women seeking clinical care and in a matched population cohort to delineate more fully the scope and magnitude of endometriosis in the context of and beyond clinical care. DESIGN:Matched-exposure cohort design. SETTING:Surgical centers in ...
journal_title:Fertility and sterility
pub_type: 杂志文章,多中心研究
doi:10.1016/j.fertnstert.2011.05.087
更新日期:2011-08-01 00:00:00
abstract::Because the size of leiomyomata uteri often decreases significantly after menopause, the authors elected to employ a long-acting gonadotropin hormone-releasing hormone analog (GnRH-alpha) (imbzl-D-His6-Pro9-Net-GnRH) to create a state of pseudomenopause in six patients with leiomyomata uteri diagnosed on the basis of ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)49332-5
更新日期:1986-05-01 00:00:00
abstract:OBJECTIVE:To confirm the advantages of goserelin prior to endometrial ablation for the treatment of dysfunctional uterine bleeding. DESIGN:Multicenter, prospective, randomized, double-blind study. PATIENT(S):Cycling premenopausal women with dysfunctional uterine bleeding. TREATMENT:Patients were randomized to gosere...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the association between fetal and maternal catechol-O-methyltransferase (COMT) Val158Met and methyl tetrahydrofolate reductase (MTHFR) C677T functional polymorphisms and preeclampsia, examining its influence on placental COMT and in maternal 2-methoxyestradiol (2-ME) plasma levels. DESIGN:Prospec...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2015.09.019
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:To determine plasma adiponectin concentration in women with and without polycystic ovary syndrome (PCOS) and to assess possible correlations of adiponectin to the hormonal and metabolic parameters, including measures of insulin resistance (IR). DESIGN:Case-control study. SETTING:Tertiary-referral university...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2004.11.077
更新日期:2005-06-01 00:00:00
abstract:OBJECTIVE:To assess bacterial colonization following balloon uterine stent placement in the uterus for 30 days. DESIGN:Prospective randomized controlled study. SETTING:Tertiary medical center. PATIENT(S):Sixty-eight women scheduled for hysteroscopy. INTERVENTION(S):Women who were undergoing hysteroscopic surgery we...
journal_title:Fertility and sterility
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.fertnstert.2014.10.032
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:To evaluate if the presence of endometriomas impacts on the ovarian reserve as evaluated with antimüllerian hormone (AMH). DESIGN:Systematic review and meta-analysis. SETTING:Not applicable. PATIENT(S):Patients with unoperated endometriomas versus controls without endometriomas. INTERVENTION(S):Electronic...
journal_title:Fertility and sterility
pub_type: 杂志文章,meta分析
doi:10.1016/j.fertnstert.2018.06.025
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVE:To describe the use of a Malecot catheter as a stent after radical trachelectomy (RT). DESIGN:Case report. SETTING:Assisted conception unit at a teaching hospital in the United Kingdom. PATIENT(S):A 36-year-old woman undergoing IVF after her cervix had been excised for cervical carcinoma. Previous attempts...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2004.11.081
更新日期:2005-06-01 00:00:00
abstract::The tenet that a combination of human follicle-stimulating hormone (hFSH)/human menopausal gonadotropin (hMG) improves follicular recruitment was assessed by randomly treating ovulatory women either with hFSH/hMG on days 3 and 4 of the cycle followed by two ampules of hMG daily or with a constant daily dose of 2 ampul...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0015-0282(16)60315-1
更新日期:1988-11-01 00:00:00
abstract:OBJECTIVE:To review the available information regarding the polypeptide factors inhibin, activin, and follistatin in reproductive physiology. DESIGN:The protein structure, tissue expression, regulation, and effects of these factors are outlined, with an emphasis on the reproductive tissues in both females and males. A...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/s0015-0282(16)58137-0
更新日期:1996-03-01 00:00:00
abstract::The force generated by the radiation pressure of a low power laser beam induces an optical trap which may be used to manipulate sperm. We studied the effect of the optical trap on sperm motility. A Nd:YAG laser beam was coupled to a conventional microscope and focused into the viewing plane by the objective lens. Sper...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract:OBJECTIVE:To prove that low-dose hCG alone can be clinically used to replace FSH-containing gonadotropins to complete controlled ovarian hyperstimulation (COH). DESIGN:Controlled, prospective, randomized study. SETTING:Academic center. PATIENT(S):Infertile patients who are candidates for assisted reproduction. INTE...
journal_title:Fertility and sterility
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.fertnstert.2005.02.036
更新日期:2005-08-01 00:00:00
abstract::A new polarographic oxygen electrode system is described which can accept sperm suspensions with volumes as low as 50 microliters. In this configuration, the electrode tip forms the base of the suspension reaction chamber, and there is no stirring. Consequently, structured fluids such as cervical mucus can be applied....
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1978-12-01 00:00:00
abstract:OBJECTIVE:To analyze the protein production into the surrounding medium (secretome) of both human and mouse embryos and correlate these findings with ongoing blastocyst development. Along with improvements in culture systems, there is renewed focus on the development of noninvasive viability assays in human IVF. Becaus...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.05.022
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVE:To analyze embryo morphology in relation to the corresponding chromosomal status, in order to evaluate the effects of aneuploidy over fragmentation, delayed cleavage, and arrested cleavage. DESIGN:Retrospective study. SETTING:Reproductive Medicine Unit, Società Italiana di Studi di Medicina della Riproduzio...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.07.1512
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:To determine whether the G1733A polymorphism of the androgen receptor gene is associated with an increased risk for recurrent spontaneous abortion (RSA). DESIGN:Case-control study. SETTING:Division of Genetics and Biotechnology, Department of Biology, University of Athens. PATIENT(S):A total of 131 women w...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.04.071
更新日期:2008-11-01 00:00:00
abstract::Because spermatocyte meiotic error results in embryonic sex chromosomal aneuploidy, it is speculated that teratospermia correlates with increased embryonic sex chromosomal abnormalities. Our findings contradict this theory, suggesting that morphology does not correlate with sex chromosomal genotype. ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.07.1006
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVE:To determine optimal management with one or two mature follicles after stimulation. DESIGN:Retrospective analysis. SETTING:Lister fertility clinic. PATIENT(S):A total of 1,350 IVF/intracytoplasmic sperm injection cycles (7.3% of total) during 1998-2009 were found to have one or two mature follicles. INTER...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2010.05.030
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:To determine the levels of metabolites surrounding the human oocyte and embryo in vivo. DESIGN:Oviduct and uterine fluids were collected throughout the menstrual cycle. Cumulus cells were collected at oocyte retrieval and their production of metabolites was assessed. Samples were analyzed for pyruvate, lacta...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)58097-2
更新日期:1996-02-01 00:00:00
abstract:OBJECTIVE:To compare the effect of high serum E(2) levels on endometrial steroid receptors in gonadotropin-stimulated cycles (hCG + 7) and natural cycles (LH + 7), and to study its effect on spheroid attachment. DESIGN:Observational. SETTING:University hospital. PATIENT(S):Infertile patient with normal menstrual cyc...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2011.06.015
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:To investigate the molecular mechanism for declining sperm motility in older men. DESIGN:Retrospective and prospective study. SETTING:University-based andrology unit. PATIENT(S):Semen was collected from 2,111 patients and sperm donors. INTERVENTION(S):None. MAIN OUTCOME MEASURE(S):Age, sperm concentratio...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2005.05.020
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVE:To develop and validate a simple and reliable single-cell analysis protocol for the preimplantation genetic diagnosis (PGD) of spinal muscular atrophy (SMA). DESIGN:Molecular tests based on specific enzymatic digestion have already been described for SMA diagnosis. We modified the amplified DNA fragments so ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2005.03.054
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of supernumerary preovulatory follicular reduction as an approach to avoid multiple pregnancies in ovulation induction or superovulation cycles. DESIGN:Retrospective study. SETTING:Tertiary referral center. PATIENT(S):In 26 cycles, 24 patients underwent ovulation induction or superov...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(01)02379-2
更新日期:2001-10-01 00:00:00
abstract:OBJECTIVE:To determine the efficacy of treating women with severe menstrual migraine headaches with GnRH agonist (GnRH-a) therapy, alone and combined with continuous estrogen-progestin "add-back." DESIGN:Nonrandomized, prospective treatment study. SETTING:Outpatient clinic in a university medical center. PATIENT(S):...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/S0015-0282(97)81928-0
更新日期:1997-02-01 00:00:00
abstract:OBJECTIVE:Compare the efficiency of two vitrification methods for single-blastomere cryopreservation with mouse or human embryos. DESIGN:Experimental prospective controlled study. SETTING:Research center. PATIENT(S):Human Blastomeres were obtained after biopsy. INTERVENTION(S):Mouse blastomeres were obtained after ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2011.10.008
更新日期:2012-01-01 00:00:00
abstract::Clearly, to provide adequate counseling to women with POF, information is critically needed concerning the background incidence of spontaneous improvement in ovarian function as well as carefully designed, controlled studies to evaluate the efficacy of presumed therapeutic intervention. The case presented herein under...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)53238-5
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVE:To explore the long-term outcome of patients who began IVF treatment by considering not only treatment outcome in the center but also the parenthood project outcome after discontinuation of unsuccessful IVF. DESIGN:Retrospective cohort follow-up study. SETTING:Two French IVF centers. PATIENT(S):Seven hundr...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.05.067
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVE:To assess the impact of embryo retention in the embryo transfer catheter followed by "immediate" retransfer on pregnancy outcome in women undergoing assisted reproduction. DESIGN:Retrospective analysis of embryo transfer following in vitro fertilization. SETTING:Assisted reproductive technology practice in ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2004.01.035
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of luteinizing hormone-releasing hormone agonist (LH-RH-a) in the treatment of leiomyomata. DESIGN:A retrospective randomized trial. SETTING:Hospital department of obstetrics and gynecology. PATIENTS:Twenty-five women, ages 36 to 54 years with symptomatic uterine leiomyomata, were ...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/s0015-0282(16)54296-4
更新日期:1991-05-01 00:00:00