smellblind: a gene required for Drosophila olfaction.

Abstract:

:In this article we define and characterize the smellblind gene (sbl). We show that two mutants, sbl and olfDx9, both isolated by virtue of their olfactory phenotypes and analyzed extensively by others with respect to courtship behavior, contain mutations at a single locus. Meiotic recombination, duplication, and deficiency mapping are used to localize this gene, sbl, to cytogenetic position 14F6-15A2-3 on the X chromosome. Mutations of the locus are shown to produce severe defects not only in larval olfactory response to several volatile chemicals, but also in larval contact chemosensory response. Both sbl and olfDx9 give a robust response, however, in a new test of larval phototactic response, which we describe here. Both alleles are shown to be heat-sensitive lethals. Four additional recessive lethal alleles, two EMS-induced, one dysgenic, and one spontaneous, are also described.

journal_name

Genetics

journal_title

Genetics

authors

Lilly M,Carlson J

subject

Has Abstract

pub_date

1990-02-01 00:00:00

pages

293-302

issue

2

eissn

0016-6731

issn

1943-2631

journal_volume

124

pub_type

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