Is there variation in crossover interference levels among chromosomes from human males?

Abstract:

:We demonstrate that recent data from human males are consistent with constant interference levels among chromosomes under the two-pathway model, whereas inappropriately fitting shape parameters of Gamma distributions to immunofluorescent interfoci distances observed on finite chromosomes generates false interpretations of higher levels of interference on shorter chromosomes. We provide appropriate statistical methodology.

journal_name

Genetics

journal_title

Genetics

authors

Housworth EA,Stahl FW

doi

10.1534/genetics.109.103853

subject

Has Abstract

pub_date

2009-09-01 00:00:00

pages

403-5

issue

1

eissn

0016-6731

issn

1943-2631

pii

genetics.109.103853

journal_volume

183

pub_type

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