Water-dispersible multifunctional hybrid nanogels for combined curcumin and photothermal therapy.

abstract：:Chitosan-silica xerogel hybrid membranes were fabricated using a sol-gel process and their potential applications in guided bone regeneration (GBR) were investigated in terms of their in vitro cellular activity and in vivo bone regeneration ability. TEM observation revealed that the silica xerogel was dispersed in the...

journal_title：Biomaterials

authors： Lee EJ,Shin DS,Kim HE,Kim HW,Koh YH,Jang JH

更新日期：2009-02-01 00:00:00

abstract：:Breast cancer is associated with high mortality due to tumor metastasis. The anti-metastasis efficacy of photochemotherapy is strictly limited by poor targeting capability with respect to circulating tumor cells (CTCs) in blood and lymph. Herein, we decorate the platelet membrane (PM) on a surface of nanoparticles (NP...

journal_title：Biomaterials

authors： Ye H,Wang K,Wang M,Liu R,Song H,Li N,Lu Q,Zhang W,Du Y,Yang W,Zhong L,Wang Y,Yu B,Wang H,Kan Q,Zhang H,Wang Y,He Z,Sun J

更新日期：2019-06-01 00:00:00

abstract：:Immediate finishing is a highly desirable property of restorative materials. In general, the resin composites, the polyacid-modified resin composites and resin-modified glass-ionomers are finished immediately after light-curing. For the conventional glass-ionomers a waiting period of 24 h is recommended. Therefore, th...

journal_title：Biomaterials

authors： Gladys S,Braem M,Van Meerbeek B,Lambrechts P,Vanherle G

更新日期：1998-03-01 00:00:00

abstract：:We have prepared unique macroporous and ordered dextran-based hydrogels using a single-step biocatalytic transesterification reaction between dextran and divinyladipate in neat dimethylsulfoxide. These hydrogels show a unimodal distribution of interconnected pores with average diameters from 0.4 to 2.0 microm dependin...

journal_title：Biomaterials

authors： Ferreira L,Gil MH,Cabrita AM,Dordick JS

更新日期：2005-08-01 00:00:00

abstract：:We studied non-implanted ultra-high molecular weight polyethylene (UHMWPE) knee components, that were gamma-sterilized in air and shelf-aged during 6 and 7 years, to explore fracture mechanisms in the degraded material. Prior to the fractography study, we assessed degradation through FTIR and optical density measureme...

journal_title：Biomaterials

authors： Puértolas JA,Larrea A,Gómez-Barrena E

更新日期：2001-08-01 00:00:00

abstract：:Intervertebral disc (IVD) degeneration is the major cause of lower back pain, while the currently available treatments are symptomatic rather than curative. Tissue engineering is a powerful therapeutic strategy that can restore the normal biomechanical motion of the human spine. The ability of a biphasic elastic scaff...

journal_title：Biomaterials

authors： Wan Y,Feng G,Shen FH,Laurencin CT,Li X

更新日期：2008-02-01 00:00:00

abstract：:Development of high selectivity, accurate targeted and noninvasive fluorescent probe for monitoring specific enzyme activity associated with the tumor is urgent needed for early diagnosis of cancer and clinical fluorescence interventional resection guidance treatment. Owing to the invasion of malignant tumor cells, tu...

journal_title：Biomaterials

authors： Li H,Yao Q,Xu F,Xu N,Duan R,Long S,Fan J,Du J,Wang J,Peng X

更新日期：2018-10-01 00:00:00

abstract：:Fluorescent Ⅱ-Ⅳ Quantum dots (QDs) have demonstrated to be highly promising biological probes for various biological and biomedical applications due to their many attractive merits, such as robust photostabilty, strong photoluminescence, and size-tunable fluorescence. Along with wide ranging bioapplications, concerns ...

journal_title：Biomaterials

authors： Su Y,Peng F,Jiang Z,Zhong Y,Lu Y,Jiang X,Huang Q,Fan C,Lee ST,He Y

更新日期：2011-09-01 00:00:00

abstract：:To study the effect of ionizable functional groups on the adhesion of leucocytes to surfaces, both poly(ethyleneimine) and poly(acrylic acid) were immobilized on polyurethane films, resulting in the introduction of amine and carboxylic acid groups, respectively. This was confirmed by contact angle measurements and XPS...

journal_title：Biomaterials

authors： Bruil A,Terlingen JG,Beugeling T,van Aken WG,Feijen J

更新日期：1992-01-01 00:00:00

abstract：:There is great demand for constructing well-organized three-dimensional (3D) tissues in vitro. Here, we developed a 3D stacked culture method using biodegradable poly(d,l-lactide-co- glycolide) (PLGA) membranes with defined topography. Pore size and porosity of the membranes can be controlled by changing the moisture ...

journal_title：Biomaterials

authors： Kasuya J,Sudo R,Tamogami R,Masuda G,Mitaka T,Ikeda M,Tanishita K

更新日期：2012-03-01 00:00:00

abstract：:The development of a method that can efficiently deliver nucleic acids into the nucleus of living systems remains one of the key challenges for experimental and therapeutic use of nonbiological gene delivery agents. In the current study, we demonstrate a functionalized gold nanoparticle (AuNP) that can serve as a univ...

journal_title：Biomaterials

authors： Kim DW,Kim JH,Park M,Yeom JH,Go H,Kim S,Han MS,Lee K,Bae J

更新日期：2011-04-01 00:00:00

abstract：:Ultrasoft biomaterials-polymers, gels, and human soft tissues with an elastic modulus less than ∼100 kPa-are increasingly used in medical devices. While bacterial interactions (adhesion and biofilm formation) have been extensively studied on stiffer materials, little is known about how bacteria colonize ultrasoft mate...

journal_title：Biomaterials

authors： Wang Y,Guan A,Isayeva I,Vorvolakos K,Das S,Li Z,Phillips KS

更新日期：2016-07-01 00:00:00

abstract：:Self-assembly is a prominent phenomenon observed in nature. Inspired by this thermodynamically favorable approach, several natural and synthetic materials have been investigated to develop functional systems for various biomedical applications, including drug delivery. Furthermore, layered self-assembled systems provi...

journal_title：Biomaterials

authors： Sarode A,Annapragada A,Guo J,Mitragotri S

更新日期：2020-02-29 00:00:00

abstract：:The purpose of this study was to access tissue reactions to the outer prismatic (prism) and the inner nacreous (nacre) layers of the fresh water Margaritifera shell. The materials, in granule form, were implanted into the back muscles and femurs of rats for 1, 2, 4, 8 and 16 weeks. In the back muscles, a foreign body ...

journal_title：Biomaterials

authors： Liao H,Mutvei H,Sjöström M,Hammarström L,Li J

更新日期：2000-03-01 00:00:00

abstract：:In normal tissue repair, macrophages exhibit a pro-inflammatory phenotype (M1) at early stages and a pro-healing phenotype (M2) at later stages. We have previously shown that M1 macrophages initiate angiogenesis while M2 macrophages promote vessel maturation. Therefore, we reasoned that scaffolds that promote sequenti...

journal_title：Biomaterials

authors： Spiller KL,Nassiri S,Witherel CE,Anfang RR,Ng J,Nakazawa KR,Yu T,Vunjak-Novakovic G

更新日期：2015-01-01 00:00:00

abstract：:In this study, modifications of glass ionomer cements (GICs) were made by adding bioactive glass (BAG) to GIC to obtain bioactive restorative materials. This study used SEM, EDS and visual analysis to examine the bioactivity and the ability of the study materials to mineralize dentin. Conventional cure and resin-modif...

journal_title：Biomaterials

authors： Yli-Urpo H,Närhi M,Närhi T

更新日期：2005-10-01 00:00:00

abstract：:Two vinyl sulfone functionalized crosslinkers were developed for the purpose of preparing degradable poly(ethylene glycol) (PEG) hydrogels (EMXL and GABA-EMXL hydrogels). A self-elimination degradation mechanism in which an N-terminal residue of a glutamine is converted to pyroglutamic acid with subsequent release of ...

journal_title：Biomaterials

authors： Deshmukh M,Singh Y,Gunaseelan S,Gao D,Stein S,Sinko PJ

更新日期：2010-09-01 00:00:00

abstract：:Hydrogels are frequently employed as medical device biomaterials due to their advantageous biological properties, e.g. resistance to infection and encrustation, biocompatibility; however, their poor mechanical properties generally limit the scope of application to coatings of medical devices. To address this limitatio...

journal_title：Biomaterials

authors： Jones DS,McLaughlin DW,McCoy CP,Gorman SP

更新日期：2005-05-01 00:00:00

abstract：:A comparative in vitro assessment of 4 types of tubing representative of the materials currently used in cardiopulmonary bypass (CPB) procedures was conducted under static conditions using liquid extracts of the materials or direct contact with fresh human blood or serum. The parameters monitored were biomarkers of co...

journal_title：Biomaterials

authors： Harmand MF,Briquet F

更新日期：1999-09-01 00:00:00

abstract：:Porous nanostructure with its unique properties is found to be able to hold promise in drug delivery. We fabricated the one-dimensional titanium dioxide whiskers (TiO2 Ws) and designed a strategy to explore their drug delivery application and anti-tumor function combined with daunorubicin (DNR). We observed good bioco...

journal_title：Biomaterials

authors： Li Q,Wang X,Lu X,Tian H,Jiang H,Lv G,Guo D,Wu C,Chen B

更新日期：2009-09-01 00:00:00

abstract：:Gold nanoparticles hold great promise as anti-cancer theranostic agents against cancer by actively targeting the tumor cells. As this potential has been supported numerously during in vitro experiments, the effective application is hampered by our limited understanding and control of the interactions within complex in...

journal_title：Biomaterials

authors： D'Hollander A,Jans H,Velde GV,Verstraete C,Massa S,Devoogdt N,Stakenborg T,Muyldermans S,Lagae L,Himmelreich U

更新日期：2017-04-01 00:00:00

abstract：:A glass of nominal composition (wt%) 17.25 MgO-52.75 3CaO.P2O5-30 SiO2 and a glass-ceramic obtained from it showed surface modifications when immersed in an acellular medium having a composition similar to that of human blood plasma. A (Ca, P)-rich layer, with an approximate Ca/P atomic ratio of 1.7, identified as hyd...

journal_title：Biomaterials

authors： Oliveira JM,Correia RN,Fernandes MH

更新日期：1995-07-01 00:00:00

abstract：:Coralline hydroxyapatite ceramics alone (control) and the ceramics combined with rat marrow cells were implanted subcutaneously in the backs of syngeneic Fischer rats and harvested at 1,2,3,4,6,8 and 24 wk after surgery. None of the control ceramics (without marrow) showed bone formation. However, ceramics combined wi...

journal_title：Biomaterials

authors： Okumura M,Ohgushi H,Tamai S

更新日期：1991-05-01 00:00:00

abstract：:The infection of an implanted prosthetic material can have serious consequences on the tissue integration of the implant and the scarring process in the host, and may even necessitate replacement of the prosthesis. This study was designed to explore the in vitro effects of Staphylococcus aureus (Sa) and Staphylococcus...

journal_title：Biomaterials

authors： Bellón JM,G-Honduvilla N,Jurado F,Carranza A,Buján J

更新日期：2001-07-01 00:00:00

abstract：:Electrical polarization and depolarization processes of the 45S5 type bioactive glass (BG) was studied by a thermally stimulated depolarization current (TSDC) and an complex impedance measurements. The depolarization processes were found to consist of three processes, which were observed as three peaks, P1, P2 and P3,...

journal_title：Biomaterials

authors： Obata A,Nakamura S,Yamashita K

更新日期：2004-09-01 00:00:00

abstract：:The effects of phosphorylated chitin (P-chitin) on the tissue responses to two kinds of calcium phosphate cements (CPCs) were investigated using experimental rabbits. One of them consisting of monocalcium phosphate monohydrate, calcium oxide, 1 M phosphate buffer (pH: 7.4) and different amounts of P-chitin (CPC-I or P...

journal_title：Biomaterials

authors： Wang X,Ma J,Feng Q,Cui F

更新日期：2002-12-01 00:00:00

abstract：:Metastasis is the major cause of high mortality in head and neck squamous cell carcinoma (HNSCC), in which HNSCC-derived cancer stem cells (CSCs) may be involved. Several reports have coupled non-viral gene delivery with RNA interference (RNAi) to target specific genes in cancer cells. However, the delivery efficiency...

journal_title：Biomaterials

authors： Lo WL,Chien Y,Chiou GY,Tseng LM,Hsu HS,Chang YL,Lu KH,Chien CS,Wang ML,Chen YW,Huang PI,Hu FW,Yu CC,Chu PY,Chiou SH

更新日期：2012-05-01 00:00:00

abstract：:Temperature-responsive polymers are attractive candidates for applications related to injectable delivery of biologically active therapeutics, such as stem cells. In this study, we evaluate the potential of thermosensitive hydroxybutyl chitosan (HBC) as a biomaterial for the culture of human mesenchymal stem cells (hM...

journal_title：Biomaterials

authors： Dang JM,Sun DD,Shin-Ya Y,Sieber AN,Kostuik JP,Leong KW

更新日期：2006-01-01 00:00:00

abstract：:The aim of this study was to identify and quantify potential regional and directional variations in the quasistatic uniaxial mechanical properties of the passive urinary bladder wall. Overall, the lower body and trigone regions demonstrated the highest degree of directional anisotropy, whereas the ventral region demon...

journal_title：Biomaterials

authors： Korossis S,Bolland F,Southgate J,Ingham E,Fisher J

更新日期：2009-01-01 00:00:00

abstract：:Particulate Bioglass is a bioactive material used in the repair of periodontal defects. This material undergoes a series of surface reactions in an aqueous environment which lead to osseointegration. The aim of this study was to determine whether these reactions exerted an antibacterial effect on a range of oral bacte...

journal_title：Biomaterials

authors： Allan I,Newman H,Wilson M

更新日期：2001-06-01 00:00:00