Plasma corin levels provide minimal prognostic utility incremental to natriuretic peptides in chronic systolic heart failure.

Abstract:

BACKGROUND:Corin is a serine protease that cleaves pro-atrial and pro-B-type natriuretic peptides into biologically active hormones. The relationship between soluble plasma corin levels, plasma natriuretic peptide levels, myocardial structure and performance, and long-term clinical outcomes in the setting of chronic systolic heart failure has not been described. METHODS AND RESULTS:In 126 patients with chronic systolic heart failure (left ventricular ejection fraction

journal_name

J Card Fail

authors

Shrestha K,Troughton RW,Borowski AG,Yandle TG,Richards AM,Klein AL,Tang WH

doi

10.1016/j.cardfail.2010.03.010

subject

Has Abstract

pub_date

2010-08-01 00:00:00

pages

621-7

issue

8

eissn

1071-9164

issn

1532-8414

pii

S1071-9164(10)00149-1

journal_volume

16

pub_type

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