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Association between prehospital delay and subsequent clinical course in patients with/hospitalized for heart failure.

Abstract：

BACKGROUND:The clinical consequences of prehospital delay in heart failure (HF) patients are unknown. This study explores the relationship between prehospital delay of HF patients and length of hospital stay, plasma values of brain natriuretic peptides (BNP) as well as the association of delay with all-cause mortality, readmission for HF, or all-cause readmissions during short- (60 days) and long-term (18 months) follow-up. METHODS:Data from 1023 hospitalized HF patients mean aged 71 years from the Coordinating study evaluating Outcomes of Advising and Counselling in HF study were analyzed. RESULTS:Patients who delayed less than 1 day had significantly shorter stay in hospital (10 days vs. 11 days, P = 0.033). They also had significantly (P = 0.004) lower median plasma values of BNP (377 pg/mL) at discharge compared to patients who delayed >24 hours (492 pg/mL). Delay was not related to all-cause mortality and/or readmissions for HF. CONCLUSION:Although patients with a prehospital delay less than 1 day were more symptomatic on admission, they had a shorter hospital stay as well as lower plasma values of BNP at discharge. Delay was not associated hospital readmissions or mortality after discharge.

journal_name

J Card Fail

journal_title

Journal of cardiac failure

authors

Johansson P,van der Wal M,van Veldhuisen DJ,Jaarsma T

doi

10.1016/j.cardfail.2011.12.007

subject

Has Abstract

pub_date

2012-03-01 00:00:00

pages

202-7

issue

3

eissn

1071-9164

issn

1532-8414

pii

S1071-9164(11)01331-5

journal_volume

18

pub_type

杂志文章,多中心研究,随机对照试验

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