Abstract:
BACKGROUND:Coronary angiography (CA) is usually performed in patients with reduced left ventricular ejection fraction (LVEF) to search ischemic cardiomyopathy. Our aim was to examine the agreement between CA and cardiovascular magnetic resonance (CMR) imaging among a cohort of patients with unexplained reduced LVEF, and estimate what would have been the consequences of using CMR imaging as the first-line examination. METHODS:Three hundred five patients with unexplained reduced LVEF of ≤45% who underwent both CA and CMR imaging were retrospectively registered. Patients were classified as CMR+ or CMR- according to presence or absence of myocardial ischemic scar, and classified CA+ or CA- according to presence or absence of significant coronary artery disease. RESULTS:CMR+ (n = 89) included all 54 CA+ patients, except 2 with distal coronary artery disease in whom no revascularization was proposed. Among the 247 CA- patients, 15% were CMR+. CMR imaging had 96% sensitivity, 85% specificity, 99% negative predictive value, and 58% positive predictive value for detecting CA+ patients. Revascularization was performed in 6.5% of the patients (all CMR+). Performing CA only for CMR+ patients would have decreased the number of CAs by 71%. CONCLUSIONS:In reduced LVEF, performing CA only in CMR+ patients may significantly decrease the number of unnecessary CAs performed, without missing any patients requiring revascularization.
journal_name
J Card Failjournal_title
Journal of cardiac failureauthors
Desroche LM,Milleron O,Safar B,Ou P,Garbarz E,Lavie-Badie Y,Abtan J,Millischer D,Pathak A,Durand-Zaleski I,Cattan S,Ronchard T,Jondeau Gdoi
10.1016/j.cardfail.2020.09.005subject
Has Abstractpub_date
2020-12-01 00:00:00pages
1067-1074issue
12eissn
1071-9164issn
1532-8414pii
S1071-9164(20)30952-0journal_volume
26pub_type
杂志文章abstract:BACKGROUND:Clinical multistage risk assessment associated with electrocardiogram (ECG) and NT-proBNP may be a feasible strategy to screen hypertrophic cardiomyopathy (HCM). We investigated the effectiveness of a screening based on ECG and NT-proBNP in first-degree relatives of patients with HCM. METHODS AND RESULTS:A ...
journal_title:Journal of cardiac failure
pub_type: 杂志文章
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journal_title:Journal of cardiac failure
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journal_title:Journal of cardiac failure
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journal_title:Journal of cardiac failure
pub_type: 杂志文章
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journal_title:Journal of cardiac failure
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journal_title:Journal of cardiac failure
pub_type: 杂志文章,多中心研究
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journal_title:Journal of cardiac failure
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journal_title:Journal of cardiac failure
pub_type: 杂志文章
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更新日期:2008-05-01 00:00:00
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journal_title:Journal of cardiac failure
pub_type: 更正并重新发布的文章,杂志文章,随机对照试验
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更新日期:2014-05-01 00:00:00
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journal_title:Journal of cardiac failure
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更新日期:2007-08-01 00:00:00
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journal_title:Journal of cardiac failure
pub_type: 杂志文章,评审
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更新日期:2002-12-01 00:00:00
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journal_title:Journal of cardiac failure
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journal_title:Journal of cardiac failure
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更新日期:2000-06-01 00:00:00
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journal_title:Journal of cardiac failure
pub_type: 杂志文章
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更新日期:2009-09-01 00:00:00
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journal_title:Journal of cardiac failure
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更新日期:2014-11-01 00:00:00
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journal_title:Journal of cardiac failure
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journal_title:Journal of cardiac failure
pub_type: 杂志文章,多中心研究
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journal_title:Journal of cardiac failure
pub_type: 杂志文章
doi:10.1016/j.cardfail.2012.11.001
更新日期:2013-01-01 00:00:00
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journal_title:Journal of cardiac failure
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journal_title:Journal of cardiac failure
pub_type: 杂志文章
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更新日期:2019-12-01 00:00:00
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journal_title:Journal of cardiac failure
pub_type: 杂志文章,多中心研究
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journal_title:Journal of cardiac failure
pub_type: 临床试验,杂志文章,随机对照试验
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