Abstract:
:Deep brain stimulation of the subthalamic nucleus (STN-DBS) improves the motor difficulties experienced by patients with Parkinson's disease (PD); however, the effects on speech are variable. In this study, patients rated their current post-surgery speech difficulties using the Voice Handicap Index (VHI) and used the same measure to retrospectively rate their pre-surgery speech. Scores pre- and post-surgery were also available on the UPDRS-III, and the patients' intelligibility was assessed by an independent listener. A control group of non-surgical patients with PD (medical group) also completed the VHI for comparison. VHI scores deteriorated equally in the two groups. However, the variability of the change scores in the surgical group was significantly greater than in the medical group. The correlation between the changes in the VHI and UPDRS scores for the surgical group was not significant. Correlations between the VHI scores and intelligibility were significant both before and after surgery, suggesting that patients accurately perceive their difficulties. The findings confirm the variability in the speech difficulties of patients following STN-DBS. The patients' ability to use the VHI offers a means of assessing the effects of their speech on their quality-of-life, and may be clinically useful post-STN-DBS.
journal_name
Int J Speech Lang Patholjournal_title
International journal of speech-language pathologyauthors
Frost E,Tripoliti E,Hariz MI,Pring T,Limousin Pdoi
10.3109/17549507.2010.497560subject
Has Abstractpub_date
2010-10-01 00:00:00pages
399-404issue
5eissn
1754-9507issn
1754-9515journal_volume
12pub_type
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journal_title:International journal of speech-language pathology
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doi:10.3109/17549507.2015.1081287
更新日期:2016-04-01 00:00:00
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journal_title:International journal of speech-language pathology
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journal_title:International journal of speech-language pathology
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journal_title:International journal of speech-language pathology
pub_type: 临床试验,杂志文章
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journal_title:International journal of speech-language pathology
pub_type: 杂志文章
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journal_title:International journal of speech-language pathology
pub_type: 杂志文章
doi:10.1080/17549507.2016.1209558
更新日期:2017-08-01 00:00:00
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journal_title:International journal of speech-language pathology
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journal_title:International journal of speech-language pathology
pub_type: 评论,杂志文章
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更新日期:2013-02-01 00:00:00
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journal_title:International journal of speech-language pathology
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doi:10.3109/17549507.2010.491130
更新日期:2011-02-01 00:00:00
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journal_title:International journal of speech-language pathology
pub_type: 杂志文章
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journal_title:International journal of speech-language pathology
pub_type: 杂志文章
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更新日期:2017-10-01 00:00:00
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journal_title:International journal of speech-language pathology
pub_type: 杂志文章
doi:10.3109/17549507.2012.702283
更新日期:2013-04-01 00:00:00
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journal_title:International journal of speech-language pathology
pub_type: 杂志文章
doi:10.3109/17549507.2012.700322
更新日期:2013-04-01 00:00:00
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journal_title:International journal of speech-language pathology
pub_type: 杂志文章
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更新日期:2020-08-01 00:00:00
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journal_title:International journal of speech-language pathology
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doi:10.3109/17549507.2013.855259
更新日期:2014-10-01 00:00:00
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更新日期:2018-02-01 00:00:00
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journal_title:International journal of speech-language pathology
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更新日期:2010-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2011-06-01 00:00:00
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