Abstract:
:Six novel subgenotypes (B7, B8, C6, C8, C9, and D6) within three hepatitis B virus (HBV) genotypes (B-D) were recently identified in Indonesia. To further characterize HBV in this country, 18 HBV-viremic samples obtained from blood donors in Nusa Tenggara, Indonesia, were subjected to phylogenetic analysis of an 1.6-kb partial or full-length sequence. Thirteen HBV isolates were classified into genotype B with four distinct subgenotypes [B3 (n = 2), B5 (n = 1), B7 (n = 4), and B8 (n = 6)], followed by 4 HBV isolates of genotype C (HBV/C); the remaining one isolate was of D (D1). As for the four HBV/C isolates, one isolate segregated into subgenotype C1, and two into C2. The remaining HBV/C isolate [C0901177(NT3)] differed from reported HBV/C isolates (C1-C9) by 4.6-7.7% over the entire genome and did not show evidence of recombination with any of the known HBV genotypes/subgenotypes, justifying its conclusive assignment into a novel subgenotype (C10) within genotype C.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Mulyanto,Depamede SN,Surayah K,Tjahyono AA,Jirintai,Nagashima S,Takahashi M,Okamoto Hdoi
10.1007/s00705-010-0628-xsubject
Has Abstractpub_date
2010-05-01 00:00:00pages
705-15issue
5eissn
0304-8608issn
1432-8798journal_volume
155pub_type
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