当前位置： SCI文献检索 > METHODS OF INFORMATION IN MEDICINE期刊下所有文献 > Estimation of patient accrual rates in clinical trials based on routine data from hospital information systems.

Estimation of patient accrual rates in clinical trials based on routine data from hospital information systems.

Abstract：

BACKGROUND:Delayed patient recruitment is a common problem in clinical trials. According to the literature, only about a third of medical research studies recruit their planned number of patients within the time originally specified. OBJECTIVES:To provide a method to estimate patient accrual rates in clinical trials based on routine data from hospital information systems (HIS). METHODS:Based on inclusion and exclusion criteria for each trial, a specific HIS report is generated to list potential trial subjects. Because not all information relevant for assessment of patient eligibility is available as coded HIS items, a sample of this patient list is reviewed manually by study physicians. Proportions of matching and non-matching patients are analyzed with a Chi-squared test. An estimation formula for patient accrual rate is derived from this data. RESULTS:The method is demonstrated with two datasets from cardiology and oncology. HIS reports should account for previous disease episodes and eliminate duplicate persons. CONCLUSION:HIS data in combination with manual chart review can be applied to estimate patient recruitment for clinical trials.

journal_name

Methods Inf Med

journal_title

Methods of information in medicine

authors

Dugas M,Amler S,Lange M,Gerss J,Breil B,Köpcke W

doi

10.3414/ME0582

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

263-6

issue

3

eissn

0026-1270

issn

2511-705X

pii

0582

journal_volume

48

pub_type

杂志文章

相关文献

METHODS OF INFORMATION IN MEDICINE文献大全
  • EEG deblurring techniques in a clinical context.

    abstract：OBJECTIVES:EEG scalp potential distributions recorded in humans are affected by low spatial resolution and by the dependence on the electrical reference used. High resolution EEG technologies are available to drastically increase the spatial resolution of the raw EEG. Such technologies include the computation of surfac...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：

    authors： Cincotti F,Babiloni C,Miniussi C,Carducci F,Moretti D,Salinari S,Pascual-Marqui R,Rossini PM,Babiloni F

    更新日期：2004-01-01 00:00:00

  • Appropriateness and necessity research on the Internet: using a "second opinion system".

    abstract：:Appropriateness and necessity research of various procedures in medicine may be the most complex field of innovation in healthcare and technology assessment. Nevertheless, the appropriateness of the indication of any medical intervention is probably more important than the outcome since even ideal quality components o...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：

    authors： Schilling J,Faisst K,Kapetanios E,Wyss P,Norrie MC,Gutzwiller F

    更新日期：2000-08-01 00:00:00

  • Harmonization of detailed clinical models with clinical study data standards.

    abstract：INTRODUCTION:This article is part of the Focus Theme of METHODS of Information in Medicine on "Managing Interoperability and Complexity in Health Systems". BACKGROUND:Data sharing and integration between the clinical research data management system and the electronic health record system remains a challenging issue. T...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：10.3414/ME13-02-0019

    authors： Jiang G,Evans J,Oniki TA,Coyle JF,Bain L,Huff SM,Kush RD,Chute CG

    更新日期：2015-01-01 00:00:00

  • A pictorial schema for a comprehensive user-oriented identification of medical Apps.

    abstract：OBJECTIVES:The huge amount of released medical apps prevents medical app users from believing that medical scientific societies and other accreditation bodies as well, have the resources and the power for assigning to any medical app a quality score. By the time being, any medical app user has to take the risks related...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：10.3414/ME13-01-0093

    authors： Bonacina S,Marceglia S,Pinciroli F

    更新日期：2014-01-01 00:00:00

  • Quantification of the Central Cardiovascular Network Applying the Normalized Short-time Partial Directed Coherence Approach in Healthy Subjects.

    abstract：BACKGROUND:The central control of the autonomic nervous system (ANS) and the complex interplay of its components can be described by a functional integrated mode - the central autonomic network (CAN). CAN represents the integrated functioning and interaction between the central nervous system (CNS) and ANS (parasympath...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：10.3414/ME17-02-0002

    authors： Schulz S,Bolz M,Bär KJ,Voss A

    更新日期：2018-05-01 00:00:00

  • Refining the Concepts of Self-quantification Needed for Health Self-management. A Thematic Literature Review.

    abstract：BACKGROUND:Questions like 'How is your health? How are you feeling? How have you been?' now can be answered in a different way due to innovative health self-quantification apps and devices. These apps and devices generate data that enable individuals to be informed and more responsible about their own health. OBJECTIV...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章,评审

    doi：10.3414/ME15-02-0007

    authors： Almalki M,Gray K,Martin-Sanchez FJ

    更新日期：2017-01-09 00:00:00

  • Read Codes Version 3: a user led terminology.

    abstract：:Version 3 of the Read Codes was designed in response to a new set of requirements generated by three new terming initiatives in the UK, the Clinical Terms Project, the Professions Allied to Medicine Terms Project and the Nursing Terms Project. The challenge was to cope with the detail required by clinical specialists ...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：

    authors： O'Neil M,Payne C,Read J

    更新日期：1995-03-01 00:00:00

  • Upper-level ontologies for health information systems. Towards an archetype patterns approach.

    abstract：OBJECTIVES:We examine the potential of archetype patterns for upper-level ontology development in health information systems (HISs). METHODS:Archetype patterns, based on the integration of archetype concepts and design patterns, are conceptualized and developed for ontology in the HIS domain. The UML provides the unde...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：10.3414/ME0519

    authors： Raghupathi W,Umar A

    更新日期：2011-01-01 00:00:00

  • An informatics benchmarking statement.

    abstract：OBJECTIVES:Benchmarking statements provide a mechanism for making academic standards explicit within a subject area. They allow comparisons between courses to be based on learning outcomes rather than by defining a curriculum. No such statement has been produced for informatics. In the absence of any established benchm...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章,评审

    doi：10.1160/me0442

    authors： Pigott K,de Lusignan S,Rapley A,Robinson J,Pritchard-Copley A

    更新日期：2007-01-01 00:00:00

  • A decision support system for diabetes care: ethical aspects.

    abstract：:In this paper the design and implementation of a decision support system for diabetes care is examined from an ethical perspective. It is noted that the system creates potential for enhancing the realization of the principle of autonomy through improved information to patients and participation by patients. However, t...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：

    authors： Collste G,Shahsavar N,Gill H

    更新日期：1999-12-01 00:00:00

  • Evaluation of the impact of a CPOE system on nurse-physician communication--a mixed method study.

    abstract：OBJECTIVES:To assess the impact of a CPOE system on medication-related communication of nurses and physicians. METHODS:In six internal medicine wards of an academic medical center, two questionnaires were used to evaluate nurses' attitudes toward the impact of a paper-based medication system and then a CPOE system on ...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：10.3414/ME0572

    authors： Pirnejad H,Niazkhani Z,van der Sijs H,Berg M,Bal R

    更新日期：2009-01-01 00:00:00

  • A reliable and efficient method for cerebral ventricular volumetry in pediatric neuroimaging.

    abstract：OBJECTIVES:Cerebral ventricular volume has the potential to become an important parameter in quantitative neurological diagnosis. However, no accepted methodology for routine clinical use exists to date. We sought a robust, reproducible, and fast technique to evaluate cerebral ventricular volume in young children. MET...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：

    authors： Hahn HK,Millar WS,Klinghammer O,Durkin MS,Tulipano PK,Peitgen HO

    更新日期：2004-01-01 00:00:00

  • The Differing Effect of Gender and Clinical Specialty on Physicians' Intention to Use Electronic Medical Record.

    abstract：BACKGROUND:The use of electronic medical record (EMR) is anticipated to bring benefits for patients, physicians, and organizations. But limited physicians' acceptance of EMR presents a serious threat to its effective implementation. OBJECTIVES:The current study incorporates technology acceptance model (TAM) with two a...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：10.1055/s-0039-1695718

    authors： Hwang HG,Dutta B,Chang HC

    更新日期：2019-12-01 00:00:00

  • On a hybrid method in dose finding studies.

    abstract：OBJECTIVES:Combination of multiple testing and modeling techniques in dose-response studies. Use of hypotheses tests to assess the significance of the dose-response signal associated with a given candidate dose-response model. Estimation of target dose(s) following the previous model selection step. Illustration of the...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：

    authors： Bretz F,Pinheiro JC,Branson M

    更新日期：2004-01-01 00:00:00

  • Integrating quantitative and qualitative methods in patient care information system evaluation: guidance for the organizational decision maker.

    abstract：OBJECTIVE:The aim of this paper is twofold. First, we describe two important dimensions of patient care information systems (PCIS) evaluation: the domain of evaluation and the different phases of the PCIS implementation. Second, we claim that, though Randomized Controlled Trials (RCTs) are often still seen as the stand...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：

    authors： Stoop AP,Berg M

    更新日期：2003-01-01 00:00:00

  • An inventory of publications on computer-based medical records: an update.

    abstract：OBJECTIVES:In 1998, we reported a steady increase in the number of publications indexed in MedLine with the MeSH term 'Medical Records Systems, Computerized'. No signs indicating an increasing interest of high-impact medical journals to publish on the computer-based patient record could be determined. In this review we...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：

    authors： Moorman PW,van der Lei J

    更新日期：2003-01-01 00:00:00

  • Transforming a hospital through growing, not building, an electronic patient record system.

    abstract：:The benefits for any health care provider of successfully introducing an Electronic Patient Record System (EPRS) into their organisation can be considerable. It has the potential to enhance both clinical care and managerial processes, as well as producing more cost-effective care and care programmes across clinical di...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：

    authors： Atkinson CJ,Peel VJ

    更新日期：1998-09-01 00:00:00

  • Information flow enables specific identification of particular physiological controllers based on their time scales.

    abstract：OBJECTIVES:Complex physiological systems, such as the cardiovascular system, controlled by the autonomic nervous system, and the gait and posture system, controlled by the sensomotor nervous system, incorporate several controllers acting at different time scales. We investigated the question, whether the information fl...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：

    authors： Hoyer D

    更新日期：2007-01-01 00:00:00

  • Statistical image reconstruction for inconsistent CT projection data.

    abstract：OBJECTIVES:The filtered backprojection is not able to cope with metal-induced inconsistencies in the Radon space which leads to artifacts in reconstructed CT images. A new algorithm is presented that reduces the drawbacks of existing artifact reduction strategies. METHODS:Inconsistent projection data are bridged by di...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：10.1160/ME9041

    authors： Buzug T,Oehler M

    更新日期：2007-01-01 00:00:00

  • Long-range correlated glucose fluctuations in diabetes.

    abstract：OBJECTIVES:Our objective is to investigate diabetes-related alteration of glucose control in diurnal fluctuations in normal daily life by detrended fluctuation analysis (DFA). METHODS:The fluctuations of glucose of 12 non-diabetic subjects and 15 diabetic patients were measured using a continuous glucose monitoring sy...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：

    authors： Ogata H,Tokuyama K,Nagasaka S,Ando A,Kusaka I,Sato N,Goto A,Ishibashi S,Kiyono K,Struzik ZR,Yamamoto Y

    更新日期：2007-01-01 00:00:00

  • Slow adaptation of ventricular repolarization as a cause of arrhythmia?

    abstract：INTRODUCTION:This article is part of the Focus Theme of Methods of Information in Medicine on "Biosignal Interpretation: Advanced Methods for Studying Cardiovascular and Respiratory Systems". BACKGROUND:Adaptation of the QT-interval to changes in heart rate reflects on the body-surface electrocardiogram the adaptation...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：10.3414/ME13-02-0039

    authors： Bueno-Orovio A,Hanson BM,Gill JS,Taggart P,Rodriguez B

    更新日期：2014-01-01 00:00:00

  • Systems analysis in health care: framework and example.

    abstract：OBJECTIVES:Due to the high complexity of structures and processes in health care, thorough systems analyses in health care run the risk of becoming very complex and difficult to handle. Therefore, we aimed to support systematic systems analysis in health care by developing a comprehensive framework that presents and de...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：

    authors： Ammenwerth E,Ehlers F,Eichstädter R,Haux R,Pohl U,Resch F

    更新日期：2002-01-01 00:00:00

  • Forecasting of life threatening arrhythmias using the compression entropy of heart rate.

    abstract：OBJECTIVES:Ventricular tachycardia (VT) provoking sudden cardiac death (SCD) are a major cause of mortality in the developed countries. The most efficient therapy for SCD prevention are implantable cardioverter defibrillators (ICD). In this study heart rate variability (HRV) measures were analyzed for short-term foreca...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：

    authors： Baumert M,Baier V,Haueisen J,Wessel N,Meyerfeldt U,Schirdewan A,Voss A

    更新日期：2004-01-01 00:00:00

  • Graphical non-linear representation of multi-dimensional laboratory measurements in their clinical context.

    abstract：:A polygon-based graphical representation of laboratory test results using nonlinear scaling is described. It is argued that the nonlinearity of the scale and the use of colors in the representation facilitates interpretation of the test result in its relationship to the standard reference range and critical clinical d...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：

    authors： Hoeke JO,Gelsema ES,Wulkan RW,Leijnse B

    更新日期：1991-04-01 00:00:00

  • Patient privacy protection using anonymous access control techniques.

    abstract：OBJECTIVE:The objective of this study is to develop a solution to preserve security and privacy in a healthcare environment where health-sensitive information will be accessed by many parties and stored in various distributed databases. The solution should maintain anonymous medical records and it should be able to lin...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：10.3414/me9116

    authors： Weerasinghe D,Rajarajan M,Elmufti K,Rakocevic V

    更新日期：2008-01-01 00:00:00

  • Introducing Information Extraction to Radiology Information Systems to Improve the Efficiency on Reading Reports.

    abstract：BACKGROUND:Radiology reports are a permanent record of patient's health information often used in clinical practice and research. Reading radiology reports is common for clinicians and radiologists. However, it is laborious and time-consuming when the amount of reports to be read is large. Assisting clinicians to locat...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：10.1055/s-0039-1694992

    authors： Xie Z,Yang Y,Wang M,Li M,Huang H,Zheng D,Shu R,Ling T

    更新日期：2019-09-01 00:00:00

  • Toward normative expert systems: Part I. The Pathfinder project.

    abstract：:Pathfinder is an expert system that assists surgical pathologists with the diagnosis of lymph-node diseases. The program is one of a growing number of normative expert systems that use probability and decision theory to acquire, represent, manipulate, and explain uncertain medical knowledge. In this article, we descri...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：

    authors： Heckerman DE,Horvitz EJ,Nathwani BN

    更新日期：1992-06-01 00:00:00

  • FreeCall, a system for emergency-call-handling support.

    abstract：:This article describes a system for the optimization of the prehospital assessment of emergency, in cases involving thoraco-abdominal complaints and consciousness problems. This assessment is performed by nurses on the basis of a telephone interview at ambulance dispatch centers. The system has a body of biomedical an...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：

    authors： Post WM,Koster W,Srámek M,Schreiber G,Zocca V,de Vries B

    更新日期：1996-09-01 00:00:00

  • Validating the knowledge base of a therapy planning system.

    abstract：:Validation of expert system knowledge bases has proved to be difficult. This paper presents a description of a system called ScriptGen that generates test data for validating the knowledge base of the ONCOCIN cancer therapy planning system. Because of the size and complexity of the ONCOCIN knowledge base, we require t...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：

    authors： Shwe MA,Tu SW,Fagan LM

    更新日期：1989-01-01 00:00:00

  • Advantages and Limitations of Leap Motion from a Developers', Physical Therapists', and Patients' Perspective.

    abstract：BACKGROUND:Physical rehabilitation exergames (PREGs) are suitable for motivating patients toward completing treatments. Leap Motion (LM) is a motion sensor that may be useful for developing PREGs targeted at hands and fingers rehabilitation. Therefore, knowing the advantages and limitations of LM is relevant to underst...

    journal_title：Methods of information in medicine

    pub_type： 杂志文章

    doi：10.1055/s-0040-1715127

    authors： Gamboa E,Serrato A,Castro J,Toro D,Trujillo M

    更新日期：2020-05-01 00:00:00