Abstract:
OBJECTIVES:Ventricular tachycardia (VT) provoking sudden cardiac death (SCD) are a major cause of mortality in the developed countries. The most efficient therapy for SCD prevention are implantable cardioverter defibrillators (ICD). In this study heart rate variability (HRV) measures were analyzed for short-term forecasting of VT in order to improve VT sensing and to enable a patient warning of forth-coming shocks. METHODS:The last 1000 normal beat-to-beat intervals before 50 VT episodes stored by the ICD were analyzed and compared to individually acquired control time series (CON). HRV analysis was performed with standard parameters of time and frequency domain as suggested by the HRV Task Force and furthermore with a newly developed and optimized nonlinear parameter that assesses the compression entropy of heart rate (Hc). RESULTS:Except of meanNN (p = 0.02) we found no significant differences in standard HRV parameters. In contrast, Hc revealed highly significant (p = 0.007) alterations in VT compared with CON suggesting a decreased complexity before the onset of VT. CONCLUSION:Compression entropy might be a suitable parameter for short-term forecasting of life-threatening tachycardia in ICD.
journal_name
Methods Inf Medjournal_title
Methods of information in medicineauthors
Baumert M,Baier V,Haueisen J,Wessel N,Meyerfeldt U,Schirdewan A,Voss Akeywords:
subject
Has Abstractpub_date
2004-01-01 00:00:00pages
202-6issue
2eissn
0026-1270issn
2511-705Xpii
04020202journal_volume
43pub_type
杂志文章abstract:OBJECTIVES:In this study, we evaluated the internal validity of EPICON, an application for grouping ICPC-coded diagnoses from electronic medical records into episodes of care. These episodes are used to estimate morbidity rates in general practice. METHODS:Morbidity rates based on EPICON were compared to a gold standa...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To explain the common conformance and interoperability testing requirements of eHealth applications through two case studies; one using a prominent eHealth messaging standard, namely HL7 v3 [1], and the other using Integrating the Healthcare Enterprise (IHE) [2] Profiles and to describe how these testing requ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME09-02-0022
更新日期:2010-01-01 00:00:00
abstract::Medical care and medical education can be supported more than in the past by using new tools and new premises for the effective linkage between bodies of knowledge and the use of that knowledge. The medical record can be converted from a source-oriented record to a problem-oriented record, enabling to trace not only w...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract::A problem of identifying the phase response curve of the myocardial pacemaker was investigated using a simple dynamic system model of cardiac arrhythmia. A hybrid optimization method of a genetic algorithm and a local optimization technique was employed to obtain a solution of the model fitting. The method was applied...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVES:The purpose of this work is to develop a health information platform connecting most health facilities in the Rhône-Alpes region. The health platform called SIS-RA is used through a Web interface. An iconic interface is dedicated to the platform and presents information in a unique way for all users. METHOD...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::A one-hundred percent documentation rate of diagnoses and patient data is unfeasible and should not be pursued. Therefore, a "lean documentation" of diagnoses and basic patient data was introduced. Coding is done by a clinic-specific list of diagnoses (thesaurus) with a minimum of diagnostic codes, combined with optio...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1997-08-01 00:00:00
abstract::A Template Definition Language (TDL) was developed to share knowledge of how to construct an electronic patient record (EPR) template. Based on the extensible markup language XML, TDL has been designed to be independent of EPR platforms or databases. Our research of TDL was conducted through evaluation of the descript...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract:OBJECTIVES:Biomedical ontologies exist to serve integration of clinical and experimental data, and it is critical to their success that they be put to widespread use in the annotation of data. How, then, can ontologies achieve the sort of user-friendliness, reliability, cost-effectiveness, and breadth of coverage that ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME9302
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Studying workflow is a critical step in designing, implementing and evaluating informatics interventions in complex sociotechnical settings, such as hospital emergency departments (EDs). Known approaches to studying workflow in clinical settings attend to the activities of individual clinicians, thus being i...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME12-01-0079
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:The central control of the autonomic nervous system (ANS) and the complex interplay of its components can be described by a functional integrated mode - the central autonomic network (CAN). CAN represents the integrated functioning and interaction between the central nervous system (CNS) and ANS (parasympath...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME17-02-0002
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVES:The log-binomial model is recommended for calculating the prevalence ratio in cross-sectional studies with binary outcomes. However, convergence problems may occur as this model is numerically unstable. If this happens, the Poisson model should be used, but the Poisson model variance needs to be adjusted. He...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.1160/me0416
更新日期:2007-01-01 00:00:00
abstract::A polygon-based graphical representation of laboratory test results using nonlinear scaling is described. It is argued that the nonlinearity of the scale and the use of colors in the representation facilitates interpretation of the test result in its relationship to the standard reference range and critical clinical d...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1991-04-01 00:00:00
abstract::Psych Topix is a knowledge-based program which guides the clinician from an on-line clinical report to a search of the psychiatric literature or of other relevant databases. It provides this guidance by using an outline of key topics in a clinical field to provide "concept-based" links. Each topic is augmented with an...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1992-09-01 00:00:00
abstract:OBJECTIVES:To assess the relevance of various potential confounding factors (comorbidities, obesity, body position, ECG lead, respiratory event type and sleep stage) on the detectability of sleep-related breathing disorders from the ECG. METHODS:A set of 140 simultaneous recordings of polysomnograms and 8-channel Holt...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME17-02-0005
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVES:Data collected within the German nosocomial infection surveillance system KISS are recommended as reference data for judging nosocomial infection rates in German intensive care units (ICUs). It is unknown whether the KISS data tend to under- or overestimate the true infection incidence rates. In this article...
journal_title:Methods of information in medicine
pub_type: 杂志文章,多中心研究
doi:
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVES:Due to the high complexity of structures and processes in health care, thorough systems analyses in health care run the risk of becoming very complex and difficult to handle. Therefore, we aimed to support systematic systems analysis in health care by developing a comprehensive framework that presents and de...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVES:a) To present a regional health care communication system developed in the North Karelia Hospital District with the help of two EU funded information technology projects namely the TERVE project (1) which was implemented at the national level financed by the regional subsidy 6 of the ERDF and the CHIN projec...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVES:The filtered backprojection is not able to cope with metal-induced inconsistencies in the Radon space which leads to artifacts in reconstructed CT images. A new algorithm is presented that reduces the drawbacks of existing artifact reduction strategies. METHODS:Inconsistent projection data are bridged by di...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.1160/ME9041
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Questions like 'How is your health? How are you feeling? How have you been?' now can be answered in a different way due to innovative health self-quantification apps and devices. These apps and devices generate data that enable individuals to be informed and more responsible about their own health. OBJECTIV...
journal_title:Methods of information in medicine
pub_type: 杂志文章,评审
doi:10.3414/ME15-02-0007
更新日期:2017-01-09 00:00:00
abstract:OBJECTIVES:We examine the potential of archetype patterns for upper-level ontology development in health information systems (HISs). METHODS:Archetype patterns, based on the integration of archetype concepts and design patterns, are conceptualized and developed for ontology in the HIS domain. The UML provides the unde...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME0519
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:To design, implement in Java, and evaluate a method and means for the automated localization of artificial landmarks in optical images for tuned-aperture computed tomography (TACT) that allows the replacement of radiographic with optical landmarks. METHODS:Circular, colored, optical landmarks were designed ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::Four tabular and two graphical techniques for the presentation of laboratory test results were evaluated in a reaction time experiment with 25 volunteers. Artificial variables and values were used to represent sets of 12 laboratory tests to eliminate the possible effects of clinical experience. Analyses focused on fou...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVES:A major problem associated with the irradiation of thoracic and abdominal tumors is respiratory motion. In clinical practice, motion compensation approaches are frequently steered by low-dimensional breathing signals (e.g., spirometry) and patient-specific correspondence models, which are used to estimate th...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME13-01-0137
更新日期:2014-01-01 00:00:00
abstract::The use of computers in the field of medical education is common. Our purpose is to present a Computer-Assisted Instruction system which has been developed over ten years at the University of Compiègne and the University of Rennes Medical School. This system can be used to help the student to solve clinical cases by a...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1994-10-01 00:00:00
abstract:OBJECTIVES:To discuss the advantages and disadvantages of an interfaced approach to clinical information systems architecture. METHODS:After many years of internally building almost all components of a hospital clinical information system (HELP) at Intermountain Health Care, we changed our architectural approach as we...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVES:The objective of this work is to present the software tool ANTONIA, which has been developed to facilitate a quantitative analysis of perfusion-weighted MRI (PWI) datasets in general as well as the subsequent multi-parametric analysis of additional datasets for the specific purpose of acute ischemic stroke p...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME14-01-0007
更新日期:2014-01-01 00:00:00
abstract::Heart rate is known to increase under the influence of increased sympathetic stimulation rates during exertion or stress. Few data are available regarding the rate response to exercise near the fatigue limit, for normal women. The effects on heart rate were studied of fatigue limiting exercise in 87 asymptomatic, norm...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract:OBJECTIVES:Personal digital assistants (PDAs) are in widespread use by resident physicians in many countries, reaching as high as 95% in some reports. Uses are varied and include clinical decision support and support of evidence-based practice. Utilization by resident doctors in Japan has not been characterized. This s...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME0607
更新日期:2009-01-01 00:00:00
abstract::HEALTH WATCH, a longitudinal prospective study of healthy aging, was designed to characterize a healthy population of 2,200 men and women, ages 20-80 years in 1970. Biochemical, hematological, and physiological tests are performed annually over three weekly visits, combined with a self-administered HEALTH WATCH questi...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract::The AVA program combines a thirty-year history with an approach that remains innovative; namely: multivariate statistical analysis on orthogonal ECG leads. Its diagnostic reference base includes only diagnoses independently verified by non-ECG criteria. The diagnostic module assesses probabilities of nine alternative ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1990-09-01 00:00:00