Abstract：
OBJECTIVES:To assess the relevance of various potential confounding factors (comorbidities, obesity, body position, ECG lead, respiratory event type and sleep stage) on the detectability of sleep-related breathing disorders from the ECG. METHODS:A set of 140 simultaneous recordings of polysomnograms and 8-channel Holter ECGs taken from 121 patients with suspected sleep related breathing disorders is stratified with respect to the named factors. Minute-by-minute apnea detection performance is assessed using separate receiver operating characteristics curves for each of the subgroups. The detection is based on parameters of heart rate, ECG amplitude and respiratory myogram interference in the ECG. We consider spectral and correlation-based features. RESULTS:The results show that typical comorbidities and supine body position impede apnea detection from the heart rate. Availability of multiple ECG-leads improves the robustness of ECG amplitude based detection with respect to posture influence. But quite robust apnea detection is achievable with even a single ECG channel - preferably lead I. Sleep stages and respiratory event type have a significant and quite consistent effect on apnea detection sensitivity with better results for light sleep stages, and worse results for REM sleep. Mixed and obstructive events are better detected than central apneas and hypopneas. CONCLUSIONS:Various factors confound the detection of sleep apnea based on the ECG. These findings should be taken into account when comparing results obtained from different data sets and may help to understand limitations of current and to improve robustness of new detection algorithms.
journal_name
Methods Inf Medjournal_title
Methods of information in medicineauthors
Maier C,Dickhaus Hdoi
10.3414/ME17-02-0005subject
Has Abstractpub_date
2018-05-01 00:00:00pages
146-151issue
3eissn
0026-1270issn
2511-705Xjournal_volume
57pub_type
杂志文章abstract：INTRODUCTION:This article is part of a Focus Theme of METHODS of Information in Medicine on Health Record Banking. BACKGROUND:Poor communication of health care information between health care providers (HCP) is still a major problem. One recent approach is the concept of Health Record Banking. OBJECTIVES:With this re...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME13-02-0003
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVES:As millions of consumers perform health information retrieval online, the mismatch between their terminology and the terminologies of the information sources could become a major barrier to successful retrievals. To address this problem, we studied the characteristics of consumer terminology for health infor...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：OBJECTIVES:In the field of open electronic health records (EHRs), openEHR as an archetype-based approach is being increasingly recognised. It is the objective of this paper to shortly describe this approach, and to analyse how openEHR archetypes impact on health professionals and semantic interoperability. METHODS:Ana...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.1160/ME5001
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVE:The objective of this study is to develop a solution to preserve security and privacy in a healthcare environment where health-sensitive information will be accessed by many parties and stored in various distributed databases. The solution should maintain anonymous medical records and it should be able to lin...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/me9116
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND:Multi-class molecular cancer classification has great potential clinical implications. Such applications require statistical methods to accurately classify cancer types with a small subset of genes from thousands of genes in the data. OBJECTIVES:This paper presents a new functional gradient descent boosting...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME11-02-0020
更新日期：2012-01-01 00:00:00
abstract：:In this paper the design and implementation of a decision support system for diabetes care is examined from an ethical perspective. It is noted that the system creates potential for enhancing the realization of the principle of autonomy through improved information to patients and participation by patients. However, t...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1999-12-01 00:00:00
abstract：OBJECTIVE:To present a geometric ruler to determine predictive values of binary diagnostic test results from prevalence, sensitivity and specificity without calculation. METHODS:On logarithmic scale the relationships between pre-/post-test odds and the likelihood ratio as well as sensitivity, specificity and the likel...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME14-01-0091
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVES:This study aims to demonstrate the usability of discourse analyses as a means of evaluating medical informatics systems by examining one particular computer-based data-to-text system for delivering neonatal health care information. METHODS:Six textual summaries of clinical information, three produced by hum...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME0613
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVES:To assess the impact of a CPOE system on medication-related communication of nurses and physicians. METHODS:In six internal medicine wards of an academic medical center, two questionnaires were used to evaluate nurses' attitudes toward the impact of a paper-based medication system and then a CPOE system on ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME0572
更新日期：2009-01-01 00:00:00
abstract：OBJECTIVES:The National Cancer Institute (NCI) has developed the Common Data Elements (CDE) to serve as a controlled vocabulary of data descriptors for cancer research, to facilitate data interchange and inter-operability between cancer research centers. We evaluated CDE's structure to see whether it could represent th...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：OBJECTIVES:To assess the effects of a CPOE system on inter-professional workflow in the medication process. METHODS:Twenty-three semi-structured interviews with physicians, nurses, and pharmacists were conducted in a Dutch academic hospital. In addition, the handwritten and system-generated documents used daily were c...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME0631
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVES:Rule induction is one of the major methods of machine learning. Rule-based models can be easily read and interpreted by humans, that makes them particularly useful in survival studies as they can help clinicians to better understand analysed data and make informed decisions about patient treatment. Although ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME13-01-0046
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVES:In this work, a cellular automaton software package for simulating different infectious diseases, storing the simulation results in a data warehouse system and analyzing the obtained results to generate prediction models as well as contingency plans, is proposed. The Brisbane H3N2 flu virus, which has been s...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME09-02-0025
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVES:This paper describes a methodology for the monitoring of the fetal cardiac health status during pregnancy, through the effective and non-invasive monitoring of the abdominal ECG signals (abdECG) of the mother. METHODS:For this purpose, a three-stage methodology has been developed. In the first stage, the fe...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME09-01-0041
更新日期：2010-01-01 00:00:00
abstract：:This editorial is part of a For-Discussion-Section of Methods of Information in Medicine about the paper "Evidence-based Health informatics: How do we know what we know?", written by Elske Ammenwerth [1]. Health informatics uses and applications have crept up on health systems over half a century, starting as simple a...
journal_title：Methods of information in medicine
pub_type： 评论,社论
doi：10.3414/ME14-10-0139
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVES:To contribute a new perspective on recent investigations into the scientific foundations of medical informatics (MI) and bioinformatics (BI). To support efforts that could generate synergies and new research directions. METHODS:MI and BI are compared and contrasted from a philosophy of science perspective. ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：:Natural language understanding systems have to exploit various kinds of knowledge in order to represent the meaning behind texts. Getting this knowledge in place is often such a huge enterprise that it is tempting to look for systems that can discover such knowledge automatically. We describe how the distinction betwe...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1998-11-01 00:00:00
abstract：:A one-hundred percent documentation rate of diagnoses and patient data is unfeasible and should not be pursued. Therefore, a "lean documentation" of diagnoses and basic patient data was introduced. Coding is done by a clinic-specific list of diagnoses (thesaurus) with a minimum of diagnostic codes, combined with optio...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1997-08-01 00:00:00
abstract：OBJECTIVES:This paper aims to present an activity-theoretical method for studying the effects of user participation in IS development. METHODS:This method is developed through a case study of the process of designing a diabetes database. RESULTS AND CONCLUSIONS:The method consists of a historical analysis of the desi...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVES:The concept of our system is not only to manage material flows, but also to provide an integrated management resource, a means of correcting errors in medical treatment, and applications to EBM (evidence-based medicine) through the data mining of medical records. METHODS:Prior to the development of this sys...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：INTRODUCTION:This article is part of the Focus Theme of METHODS of Information in Medicine on "Managing Interoperability and Complexity in Health Systems". BACKGROUND:Data sharing and integration between the clinical research data management system and the electronic health record system remains a challenging issue. T...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME13-02-0019
更新日期：2015-01-01 00:00:00
abstract：:A Template Definition Language (TDL) was developed to share knowledge of how to construct an electronic patient record (EPR) template. Based on the extensible markup language XML, TDL has been designed to be independent of EPR platforms or databases. Our research of TDL was conducted through evaluation of the descript...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2000-03-01 00:00:00
abstract：:Version 3 of the Read Codes was designed in response to a new set of requirements generated by three new terming initiatives in the UK, the Clinical Terms Project, the Professions Allied to Medicine Terms Project and the Nursing Terms Project. The challenge was to cope with the detail required by clinical specialists ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：OBJECTIVES:To find discriminative combination of influential factors of Intracerebral hematoma (ICH) to cluster ICH patients with similar features to explore relationship among influential factors and 30-day mortality of ICH. METHODS:The data of ICH patients are collected. We use a decision tree to find discriminative...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME15-01-0137
更新日期：2016-10-17 00:00:00
abstract：:Although arterial mechanical properties have been evaluated using arterial input impedance, the relative difficulty in accurate flow measurement made the value of impedance somewhat limited. To develop an alternative method to evaluate arterial mechanical properties, we analyzed the aortic pressure (AoP)-radial arteri...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
abstract：OBJECTIVES:The objective of this study was to explore suitable spatial filters for inverse estimation of cortical potentials from the scalp electroencephalogram. The effect of incorporating noise covariance into inverse procedures was examined by computer simulations and tested in human experiment. METHODS:The paramet...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:The PHOENIX Radiology Consultant is a rule-based expert system which assists physicians in planning radiological work-up strategies. This article describes the methods used to create and validate the system's knowledge base. The feasibility and acceptability of PHOENIX were tested for two years in a clinical trial. Du...
journal_title：Methods of information in medicine
pub_type： 临床试验,杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：OBJECTIVE:Pulmonary disorders are frequently characterized by the presence of adventitious sounds added to the breathing or base lung sound (BLS). The aim of this work was to assess the features of BLS in extrinsic allergic alveolitis (EAA) patients in comparison to healthy subjects, applying linear and nonlinear analy...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME12-01-0037
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVES:Lifestyle has a major influence on the development and progression of atherosclerosis. Our motto for healthy habits is "give up one, reduce two, and increase three". The one thing that is to be given up is smoking. The two things that are to be reduced are intake of food and alcohol. The three things that ar...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:Psych Topix is a knowledge-based program which guides the clinician from an on-line clinical report to a search of the psychiatric literature or of other relevant databases. It provides this guidance by using an outline of key topics in a clinical field to provide "concept-based" links. Each topic is augmented with an...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1992-09-01 00:00:00
