Abstract：
OBJECTIVES:To design, implement in Java, and evaluate a method and means for the automated localization of artificial landmarks in optical images for tuned-aperture computed tomography (TACT) that allows the replacement of radiographic with optical landmarks. METHODS:Circular, colored, optical landmarks were designed to provide flexibility with regard to landmark constellation, imaging equipment, and lighting conditions. The landmark detection was based on Hough transforms (HT) for ellipses and lines. The HT for ellipses was extended to enable selective detection of bright ellipses on a dark background and vice versa, and the number of irrelevant votes in the accumulator arrays was reduced. An experiment was performed in vitro to test the automated landmark localization scheme, verify registration accuracy, and measure the required computation time. RESULTS:A visual evaluation of the tomographic slices that were produced using the new method revealed good registration accuracy. A comparison to tomographic slices similarly produced by means of conventional TACT showed identical results. The algorithm ran sufficiently fast on standard hardware to allow landmark localization in "real time" during successive image acquisition in clinical applications. CONCLUSIONS:The proposed method provides robust automated localization of landmarks in optical images. Using a hybrid imaging system, TACT can now be clinically applied without manual interaction of a human operator and without radiopaque landmarks, which might cover anatomic details of diagnostic interest.
journal_name
Methods Inf Medjournal_title
Methods of information in medicineauthors
Linnenbrügger NI,Webber RL,Kobbelt LP,Lehmann TMkeywords:
subject
Has Abstractpub_date
2004-01-01 00:00:00pages
315-9issue
4eissn
0026-1270issn
2511-705Xpii
04040315journal_volume
43pub_type
杂志文章abstract：OBJECTIVES:The log-binomial model is recommended for calculating the prevalence ratio in cross-sectional studies with binary outcomes. However, convergence problems may occur as this model is numerically unstable. If this happens, the Poisson model should be used, but the Poisson model variance needs to be adjusted. He...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.1160/me0416
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVES:EEG scalp potential distributions recorded in humans are affected by low spatial resolution and by the dependence on the electrical reference used. High resolution EEG technologies are available to drastically increase the spatial resolution of the raw EEG. Such technologies include the computation of surfac...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:This editorial is part of a For-Discussion-Section of Methods of Information in Medicine about the paper "Evidence-based Health informatics: How do we know what we know?", written by Elske Ammenwerth [1]. Health informatics uses and applications have crept up on health systems over half a century, starting as simple a...
journal_title：Methods of information in medicine
pub_type： 评论,社论
doi：10.3414/ME14-10-0139
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVES:To assess the relevance of various potential confounding factors (comorbidities, obesity, body position, ECG lead, respiratory event type and sleep stage) on the detectability of sleep-related breathing disorders from the ECG. METHODS:A set of 140 simultaneous recordings of polysomnograms and 8-channel Holt...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME17-02-0005
更新日期：2018-05-01 00:00:00
abstract：OBJECTIVES:GTDS is a documentation system used by more than 40 German hospital cancer registries. This paper discusses the factors that contributed to its success concerning design, development, and routine use. METHODS:Success is measured in terms of the system's financial independence of public grants and its succes...
journal_title：Methods of information in medicine
pub_type： 杂志文章,评审
doi：
更新日期：2006-01-01 00:00:00
abstract：OBJECTIVES:The main objective of the research is an application of the clustering and cluster validity methods to estimate the number of clusters in cancer tumor datasets. A weighed voting technique is going to be used to improve the prediction of the number of clusters based on different data mining techniques. These ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：OBJECTIVE:Recent results published by Coste et al. in discriminant analysis with ordinal responses showed the superiority of optimal discriminating analysis for ordinal responses (ODAO) both in terms of classification and simplicity of implementation compared to classic methods (Fisher's discrimination, logistic regres...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVES:The aging of the population creates pressure on the healthcare systems in various ways. A massive increase of chronic disease conditions and age-related illness are predicted as the dominant forces driving the future health care. The objective of this paper is to present future research demands in pervasive ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME09-02-0044
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVES:Data collected within the German nosocomial infection surveillance system KISS are recommended as reference data for judging nosocomial infection rates in German intensive care units (ICUs). It is unknown whether the KISS data tend to under- or overestimate the true infection incidence rates. In this article...
journal_title：Methods of information in medicine
pub_type： 杂志文章,多中心研究
doi：
更新日期：2006-01-01 00:00:00
abstract：OBJECTIVE:Record linkage of patient data originating from various data sources and record linkage for checking uniqueness of patient registration are common tasks for every cancer registry. In Austria, there is no unique person identifier in use in the medical system. Hence, it was necessary and the goal of this work t...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVES:Benchmarking statements provide a mechanism for making academic standards explicit within a subject area. They allow comparisons between courses to be based on learning outcomes rather than by defining a curriculum. No such statement has been produced for informatics. In the absence of any established benchm...
journal_title：Methods of information in medicine
pub_type： 杂志文章,评审
doi：10.1160/me0442
更新日期：2007-01-01 00:00:00
abstract：:We present an algorithm for reconstructing the bifurcation structure of a dynamical system from time series. The method consists in finding a parameterized predictor function whose bifurcation structure is similar to that of the given system. Nonlinear autoregressive (NAR) models with polynomial terms are employed as ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：OBJECTIVE:Clinical guidelines are special types of plans realized by collective agents. We provide an ontological theory of such plans that is designed to support the construction of a framework in which guideline-based information systems can be employed in the management of workflow in health care organizations. MET...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：:Four tabular and two graphical techniques for the presentation of laboratory test results were evaluated in a reaction time experiment with 25 volunteers. Artificial variables and values were used to represent sets of 12 laboratory tests to eliminate the possible effects of clinical experience. Analyses focused on fou...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：OBJECTIVES:Ventricular tachycardia (VT) provoking sudden cardiac death (SCD) are a major cause of mortality in the developed countries. The most efficient therapy for SCD prevention are implantable cardioverter defibrillators (ICD). In this study heart rate variability (HRV) measures were analyzed for short-term foreca...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:Medical care and medical education can be supported more than in the past by using new tools and new premises for the effective linkage between bodies of knowledge and the use of that knowledge. The medical record can be converted from a source-oriented record to a problem-oriented record, enabling to trace not only w...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1989-11-01 00:00:00
abstract：BACKGROUND:Patients often fail to adhere to clinical recommendations when using current blood pressure self-measurement (BPSM) methods and equipment. As existing BPSM equipment is not able to detect non-adherent behavior, this could result in misdiagnosis and treatment error. To overcome this problem, we suggest introd...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME13-01-0032
更新日期：2014-01-01 00:00:00
abstract：:A rough-sets approach was applied to a data set consisting of animal study results and other compound characteristics to generate local and global (certain/possible) sets of rules for prediction of developmental toxicity in human subjects. A modified version of the rough-sets approach is proposed to allow the construc...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1993-02-01 00:00:00
abstract：OBJECTIVES:A low rate of newly developed pressure ulcers is considered as an important quality indicator in nursing. However, the result of a hospital depends not only on the quality of care but on the risk profile of its patients as well. Therefore, based on multiple logistic regression models we describe a method for...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME10-01-0019
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND:Traditional rehabilitation sessions are often a slow, tedious, disempowering and non-motivational process, supported by clinical assessment tools, i.e. evaluation scales that are prone to subjective rating and imprecise interpretation of patient's performance. Poor patient motivation and insufficient accurac...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME16-02-0013
更新日期：2017-03-23 00:00:00
abstract：OBJECTIVES:Personal digital assistants (PDAs) are in widespread use by resident physicians in many countries, reaching as high as 95% in some reports. Uses are varied and include clinical decision support and support of evidence-based practice. Utilization by resident doctors in Japan has not been characterized. This s...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME0607
更新日期：2009-01-01 00:00:00
abstract：OBJECTIVES:Lifestyle has a major influence on the development and progression of atherosclerosis. Our motto for healthy habits is "give up one, reduce two, and increase three". The one thing that is to be given up is smoking. The two things that are to be reduced are intake of food and alcohol. The three things that ar...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVES:In this study, we evaluated the internal validity of EPICON, an application for grouping ICPC-coded diagnoses from electronic medical records into episodes of care. These episodes are used to estimate morbidity rates in general practice. METHODS:Morbidity rates based on EPICON were compared to a gold standa...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVES:To identify factors associated with hospital length of stay (LOS) and to model variations in LOS within Diagnosis Related Groups (DRGs). METHODS:A proportional hazards frailty modelling approach is proposed that accounts for patient transfers and the inherent correlation of patients clustered within hospita...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：INTRODUCTION:This article is part of the Focus Theme of Methods of Information in Medicine on "Biosignal Interpretation: Advanced Methods for Studying Cardiovascular and Respiratory Systems". BACKGROUND:Adaptation of the QT-interval to changes in heart rate reflects on the body-surface electrocardiogram the adaptation...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME13-02-0039
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVES:A major problem associated with the irradiation of thoracic and abdominal tumors is respiratory motion. In clinical practice, motion compensation approaches are frequently steered by low-dimensional breathing signals (e.g., spirometry) and patient-specific correspondence models, which are used to estimate th...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME13-01-0137
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVES:The traditional techniques of data analysis are often not sufficient to characterize the complex dynamics of respiration. In this study the respiratory pattern variability was analyzed using symbolic dynamics. METHODS:A group of 20 patients on weaning trials from mechanical ventilation were studied at two d...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVES:Today's socio-economic developments in the healthcare area require continued optimization of processes and cost structures at hospitals, often associated with process changes for different occupational groups in the hospital. Formal methods for managing change have been established in other industries. The g...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME9235
更新日期：2009-01-01 00:00:00
abstract：UNLABELLED:The HL7 Clinical Document Architecture (CDA) is an important XML-based standard for the representation of clinical documents. OBJECTIVES:The use of Markup Languages could satisfy the demands of involved healthcare staff as well as the needs of patients, to receive an overview of the patient's treatment duri...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:A non-parametric method is presented for modelling nonlinear dynamic mechanisms of respiratory sinus arrhythmia (RSA) in anesthesia caused by positive pressure ventilation. RR interval sequences are shown with Tsay's linearity test to contain both short-term and long-term nonlinear components, which cannot completely ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
