Accurate variance estimation for prevalence ratios.

Abstract:

OBJECTIVES:The log-binomial model is recommended for calculating the prevalence ratio in cross-sectional studies with binary outcomes. However, convergence problems may occur as this model is numerically unstable. If this happens, the Poisson model should be used, but the Poisson model variance needs to be adjusted. Here, we compare different adjustments. METHODS:Using simulation we evaluated the performance of Poisson models with i) a robust variance, ii) the scale parameter adjusted by Pearson's chi-square, and iii) the scale parameter adjusted by the deviance. These models were compared with the log-binomial model with respect to hypothesis testing. Confounding and effect modification are considered. RESULTS:All adjustment models improved the variance estimation. The Poisson model with a robust variance performed best. When the log-binomial model is numerically stable as well as unstable, this model yields reasonable power and type I error values. But the Poisson model with the scale parameter adjusted by Pearson's chi-square also showed good results. CONCLUSIONS:When estimating prevalence ratios, if the log-binomial fails to converge, we recommend the Poisson model with a robust estimate of variance.

journal_name

Methods Inf Med

authors

Wolkewitz M,Bruckner T,Schumacher M

doi

10.1160/me0416

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

567-71

issue

5

eissn

0026-1270

issn

2511-705X

pii

07050567

journal_volume

46

pub_type

杂志文章
  • The Rhône-Alpes health platform.

    abstract:OBJECTIVES:The purpose of this work is to develop a health information platform connecting most health facilities in the Rhône-Alpes region. The health platform called SIS-RA is used through a Web interface. An iconic interface is dedicated to the platform and presents information in a unique way for all users. METHOD...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Durand T,Spacagna H,Verdier C,Biron P,Flory A

    更新日期:2007-01-01 00:00:00

  • Reliable blood pressure self-measurement in the obstetric waiting room.

    abstract:BACKGROUND:Patients often fail to adhere to clinical recommendations when using current blood pressure self-measurement (BPSM) methods and equipment. As existing BPSM equipment is not able to detect non-adherent behavior, this could result in misdiagnosis and treatment error. To overcome this problem, we suggest introd...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:10.3414/ME13-01-0032

    authors: Wagner S,Kamper CH,Rasmussen NH,Ahrendt P,Toftegaard TS,Bertelsen OW

    更新日期:2014-01-01 00:00:00

  • Cognitive tools in medical teamwork: the spatial arrangement of patient records.

    abstract:OBJECTIVES:As a preliminary for the design of Computer-Based Patient Records, the aim of this paper is to build an understanding of the roles physical artifacts like paper-based patient records play in supporting cognition and collaboration in the health-care settings. METHOD:A small ethnographically-informed study wa...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Bång M,Timpka T

    更新日期:2003-01-01 00:00:00

  • An intelligent Computer-Assisted Instruction system for clinical case teaching.

    abstract::The use of computers in the field of medical education is common. Our purpose is to present a Computer-Assisted Instruction system which has been developed over ten years at the University of Compiègne and the University of Rennes Medical School. This system can be used to help the student to solve clinical cases by a...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Fontaine D,Le Beux P,Riou C,Jacquelinet C

    更新日期:1994-10-01 00:00:00

  • FreeCall, a system for emergency-call-handling support.

    abstract::This article describes a system for the optimization of the prehospital assessment of emergency, in cases involving thoraco-abdominal complaints and consciousness problems. This assessment is performed by nurses on the basis of a telephone interview at ambulance dispatch centers. The system has a body of biomedical an...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Post WM,Koster W,Srámek M,Schreiber G,Zocca V,de Vries B

    更新日期:1996-09-01 00:00:00

  • The Differing Effect of Gender and Clinical Specialty on Physicians' Intention to Use Electronic Medical Record.

    abstract:BACKGROUND:The use of electronic medical record (EMR) is anticipated to bring benefits for patients, physicians, and organizations. But limited physicians' acceptance of EMR presents a serious threat to its effective implementation. OBJECTIVES:The current study incorporates technology acceptance model (TAM) with two a...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:10.1055/s-0039-1695718

    authors: Hwang HG,Dutta B,Chang HC

    更新日期:2019-12-01 00:00:00

  • A philosophy for health informatics education in developing countries: Nigeria as a case study.

    abstract::The use of computers in the health sector has increased significantly during the last few years in Nigeria. This paper addresses the integration of health and informatics education, or health education and informatics education, or informatics education in health care delivery. It gives an introduction to the status o...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Akinde AD,Soriyan HA,Adagunodo ER

    更新日期:1997-02-01 00:00:00

  • Forecasting of life threatening arrhythmias using the compression entropy of heart rate.

    abstract:OBJECTIVES:Ventricular tachycardia (VT) provoking sudden cardiac death (SCD) are a major cause of mortality in the developed countries. The most efficient therapy for SCD prevention are implantable cardioverter defibrillators (ICD). In this study heart rate variability (HRV) measures were analyzed for short-term foreca...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Baumert M,Baier V,Haueisen J,Wessel N,Meyerfeldt U,Schirdewan A,Voss A

    更新日期:2004-01-01 00:00:00

  • Use of logistic regression for developing risk-adjusted quality indicators in nursing.

    abstract:OBJECTIVES:A low rate of newly developed pressure ulcers is considered as an important quality indicator in nursing. However, the result of a hospital depends not only on the quality of care but on the risk profile of its patients as well. Therefore, based on multiple logistic regression models we describe a method for...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:10.3414/ME10-01-0019

    authors: Kutschmann M,Renner D,Fischer B

    更新日期:2010-01-01 00:00:00

  • Linear and nonlinear analysis of base lung sound in extrinsic allergic alveolitis patients in comparison to healthy subjects.

    abstract:OBJECTIVE:Pulmonary disorders are frequently characterized by the presence of adventitious sounds added to the breathing or base lung sound (BLS). The aim of this work was to assess the features of BLS in extrinsic allergic alveolitis (EAA) patients in comparison to healthy subjects, applying linear and nonlinear analy...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:10.3414/ME12-01-0037

    authors: Charleston-Villalobos S,Albuerne-Sanchez L,Gonzalez-Camarena R,Mejia-Avila M,Carrillo-Rodriguez G,Aljama-Corrales T

    更新日期:2013-01-01 00:00:00

  • Effects of record linkage errors on disease registration.

    abstract::Reliable record linkage is a prerequisite for high-quality population-based disease registration. Rapid developments in computer processing have made record linkage both more efficient and more reliable in recent years. At the same time, concerns about confidentiality increasingly hinder record linkage in many disease...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Brenner H,Schmidtmann I

    更新日期:1998-01-01 00:00:00

  • The young person's guide to biomedical informatics.

    abstract:OBJECTIVE:To draw a parallel between the challenges by which a research department in biomedical informatics is confronted and those of a symphony orchestra; in both areas different disciplines and various groups of instruments can be discerned. METHOD:Retrospective, personal review of how to conduct biomedical resear...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: van Bemmel JH

    更新日期:2006-01-01 00:00:00

  • Linked Records of Children with Traumatic Brain Injury. Probabilistic Linkage without Use of Protected Health Information.

    abstract:OBJECTIVE:Record linkage may create powerful datasets with which investigators can conduct comparative effectiveness studies evaluating the impact of tests or interventions on health. All linkages of health care data files to date have used protected health information (PHI) in their linkage variables. A technique to l...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:10.3414/ME14-01-0093

    authors: Bennett TD,Dean JM,Keenan HT,McGlincy MH,Thomas AM,Cook LJ

    更新日期:2015-01-01 00:00:00

  • A Generic Data Harmonization Process for Cross-linked Research and Network Interaction. Construction and Application for the Lung Cancer Phenotype Database of the German Center for Lung Research.

    abstract:OBJECTIVE:Joint data analysis is a key requirement in medical research networks. Data are available in heterogeneous formats at each network partner and their harmonization is often rather complex. The objective of our paper is to provide a generic approach for the harmonization process in research networks. We applied...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:10.3414/ME14-02-0030

    authors: Firnkorn D,Ganzinger M,Muley T,Thomas M,Knaup P

    更新日期:2015-01-01 00:00:00

  • Monitoring nocturnal heart rate with bed sensor.

    abstract:INTRODUCTION:This article is part of the Focus Theme of Methods of Information in Medicine on "Biosignal Interpretation: Advanced Methods for Studying Cardiovascular and Respiratory Systems". OBJECTIVES:The aim of this study is to assess the reliability of the estimated Nocturnal Heart Rate (HR), recorded through a be...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:10.3414/ME13-02-0053

    authors: Migliorini M,Kortelainen JM,Pärkkä J,Tenhunen M,Himanen SL,Bianchi AM

    更新日期:2014-01-01 00:00:00

  • Boosting in Nonlinear Regression Models with an Application to DCE-MRI Data.

    abstract:BACKGROUND:For the statistical analysis of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) data, compartment models are a commonly used tool. By these models, the observed uptake of contrast agent in some tissue over time is linked to physiologic properties like capillary permeability and blood flow. Up ...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:10.3414/ME14-01-0131

    authors: Feilke M,Bischl B,Schmid VJ,Gertheiss J

    更新日期:2016-01-01 00:00:00

  • Effectiveness of lexico-syntactic pattern matching for ontology enrichment with clinical documents.

    abstract:OBJECTIVE:To evaluate the effectiveness of a lexico-syntactic pattern (LSP) matching method for ontology enrichment using clinical documents. METHODS:Two domains were separately studied using the same methodology. We used radiology documents to enrich RadLex and pathology documents to enrich National Cancer Institute ...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:10.3414/ME10-01-0020

    authors: Liu K,Chapman WW,Savova G,Chute CG,Sioutos N,Crowley RS

    更新日期:2011-01-01 00:00:00

  • Acquisition and analysis of repeating patterns in time-oriented clinical data.

    abstract:OBJECTIVES:(1) Creation of an expressive language for specification of temporal patterns in clinical domains, (2) Development of a graphical knowledge-acquisition tool allowing expert physicians to define meaningful domain-specific patterns, (3) Implementation of an interpreter capable of detecting such patterns in cli...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Chakravarty S,Shahar Y

    更新日期:2001-01-01 00:00:00

  • Exploring the ontology of surgical procedures in the Read Thesaurus.

    abstract::The Read Thesaurus is a comprehensive user-led clinical vocabulary developed from earlier, and structurally simpler, versions of the Read Codes, with substantial input from United Kingdom health care professionals. A constituent template table underpins a range of functions, including semantic definition of concepts u...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Price C,O'Neil M,Bentley TE,Brown PJ

    更新日期:1998-11-01 00:00:00

  • An approach to policy analysis and development of medical informatics.

    abstract::There are three grand challenges for medical informatics policy: (1) What is it? (2) What should it be? (3) How can we influence its development? To address these challenges requires: (1) an historical analysis of medical informatics policies in a representative sample of countries. This should include an account of m...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Power M

    更新日期:1999-12-01 00:00:00

  • Introducing Information Extraction to Radiology Information Systems to Improve the Efficiency on Reading Reports.

    abstract:BACKGROUND:Radiology reports are a permanent record of patient's health information often used in clinical practice and research. Reading radiology reports is common for clinicians and radiologists. However, it is laborious and time-consuming when the amount of reports to be read is large. Assisting clinicians to locat...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:10.1055/s-0039-1694992

    authors: Xie Z,Yang Y,Wang M,Li M,Huang H,Zheng D,Shu R,Ling T

    更新日期:2019-09-01 00:00:00

  • Building a comprehensive clinical information system from components. The approach at Intermountain Health Care.

    abstract:OBJECTIVES:To discuss the advantages and disadvantages of an interfaced approach to clinical information systems architecture. METHODS:After many years of internally building almost all components of a hospital clinical information system (HELP) at Intermountain Health Care, we changed our architectural approach as we...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Clayton PD,Narus SP,Huff SM,Pryor TA,Haug PJ,Larkin T,Matney S,Evans RS,Rocha BH,Bowes WA 3rd,Holston FT,Gundersen ML

    更新日期:2003-01-01 00:00:00

  • Optimising Health Informatics Outcomes--Getting Good Evidence to Where it Matters.

    abstract::This editorial is part of a For-Discussion-Section of Methods of Information in Medicine about the paper "Evidence-based Health informatics: How do we know what we know?", written by Elske Ammenwerth [1]. Health informatics uses and applications have crept up on health systems over half a century, starting as simple a...

    journal_title:Methods of information in medicine

    pub_type: 评论,社论

    doi:10.3414/ME14-10-0139

    authors: Rigby M

    更新日期:2015-01-01 00:00:00

  • Information flow enables specific identification of particular physiological controllers based on their time scales.

    abstract:OBJECTIVES:Complex physiological systems, such as the cardiovascular system, controlled by the autonomic nervous system, and the gait and posture system, controlled by the sensomotor nervous system, incorporate several controllers acting at different time scales. We investigated the question, whether the information fl...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Hoyer D

    更新日期:2007-01-01 00:00:00

  • Usability Evaluation of a Distributed User Interface Application for Visuomotor Organization Assessment.

    abstract:BACKGROUND:This article describes the development and evaluation of a distributed user interface (DUI) application to assess visuomotor organization ability. This application enables therapists to evaluate the acquired brain injury (ABI) on patients, and patients, to perform the assessment on a touch screen while thera...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:10.1055/s-0040-1713086

    authors: Cuerda C,Romero-Ayuso D,Gallud JA,Morales C,Tesoriero R,Triviño-Juarez JM,Fardoun HM

    更新日期:2020-12-01 00:00:00

  • A computer-assisted drug prescription system: the model and its implementation in the ATM knowledge base.

    abstract::Informatisation of drug prescription is an important topic in medical informatics. For several years now, computerized drug databases have been implemented. Usually only a small part of the prescriptions can be stored in prescription systems because of the format of the included information; prescriptions contain esse...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Riou C,Pouliquen B,Le Beux P

    更新日期:1999-03-01 00:00:00

  • Integrating quantitative and qualitative methods in patient care information system evaluation: guidance for the organizational decision maker.

    abstract:OBJECTIVE:The aim of this paper is twofold. First, we describe two important dimensions of patient care information systems (PCIS) evaluation: the domain of evaluation and the different phases of the PCIS implementation. Second, we claim that, though Randomized Controlled Trials (RCTs) are often still seen as the stand...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Stoop AP,Berg M

    更新日期:2003-01-01 00:00:00

  • Planning of a therapeutic comparison by consideration of objective and subjective responses.

    abstract::Often in drug trials only the objective, or the subjective responses of the subjects are investigated, depending on the kind of drug. It is, however, desirable to check both the objective and the subjective responses in every drug trial. The investigation of the objective symptoms which is especially necessary in psyc...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: von Eiff AW

    更新日期:1963-01-01 00:00:00

  • DataGrid, prototype of a biomedical grid.

    abstract:BACKGROUND:The availability of large amounts of data in heterogeneous formats and the rapid progress in fields such as computer based drug design, medical imaging and medical simulations have lead to a growing demand for large computational power and easy accessibility to heterogeneous data sources. OBJECTIVES:The goa...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Breton V,Medina R,Montagnat J

    更新日期:2003-01-01 00:00:00

  • A compartmental model for simulation of IGF-I kinetics and metabolism.

    abstract::A compartmental model for the simulation of in-vivo insulin-like growth factor one (IGF-I) kinetics and metabolism is presented. The model is based on the concept that IGF binding proteins (IGFBPs) act as a reservoir for IGF-I in plasma, thereby restricting its access to the extravascular space. The model is divided i...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Boroujerdi MA,Sonksen PH,Jones RH

    更新日期:1994-12-01 00:00:00