Abstract:
OBJECTIVES:The traditional techniques of data analysis are often not sufficient to characterize the complex dynamics of respiration. In this study the respiratory pattern variability was analyzed using symbolic dynamics. METHODS:A group of 20 patients on weaning trials from mechanical ventilation were studied at two different pressure support ventilation levels. Breath duration (T(TOT)) time series and the relation T(I)/T(TOT), that contains the influence of inspiratory time (T(I)), were considered. Length-3 words and 3 different symbols were proposed. The incidence of the overlapping tau and the parameter alpha were analyzed. RESULTS:From the breath duration time series, the distribution of words with probability of occurrence higher than 6% was concentrated on one word for low respiratory variability, whereas high variability was characterized by 4 words, presenting a statistically significant difference (p = 0.0005). The probability occurrence of words "110" and "111" was also significantly different (p= 0.0005) when comparing both variabilities. CONCLUSION:The analysis carried out obtained discriminant functions able to correctly classify all the testing set series. These results permit the consideration of symbolic dynamics as a promising methodology to study the respiratory pattern variability.
journal_name
Methods Inf Medjournal_title
Methods of information in medicineauthors
Caminal P,Mateu J,Vallverdú M,Giraldo B,Benito S,Voss Akeywords:
subject
Has Abstractpub_date
2004-01-01 00:00:00pages
22-5issue
1eissn
0026-1270issn
2511-705Xpii
04010022journal_volume
43pub_type
杂志文章abstract::A Template Definition Language (TDL) was developed to share knowledge of how to construct an electronic patient record (EPR) template. Based on the extensible markup language XML, TDL has been designed to be independent of EPR platforms or databases. Our research of TDL was conducted through evaluation of the descript...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract:OBJECTIVES:The objective of this work is to present the software tool ANTONIA, which has been developed to facilitate a quantitative analysis of perfusion-weighted MRI (PWI) datasets in general as well as the subsequent multi-parametric analysis of additional datasets for the specific purpose of acute ischemic stroke p...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME14-01-0007
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:To design, implement in Java, and evaluate a method and means for the automated localization of artificial landmarks in optical images for tuned-aperture computed tomography (TACT) that allows the replacement of radiographic with optical landmarks. METHODS:Circular, colored, optical landmarks were designed ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVES:(1) Creation of an expressive language for specification of temporal patterns in clinical domains, (2) Development of a graphical knowledge-acquisition tool allowing expert physicians to define meaningful domain-specific patterns, (3) Implementation of an interpreter capable of detecting such patterns in cli...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::The medical information systems of the future will probably include the entire medical record as well as a knowledge base, providing decision support for the physician during patient care. Data dictionaries will play an important role in integrating the medical knowledge bases with the clinical databases. This article...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1989-04-01 00:00:00
abstract::During the last decade there has been a wealth of papers discussing the development of scoring systems in medicine, some of which have led to fully operational computer-aided diagnostic systems. In this paper we sketch the development of a simple scoring system for one of the more common rheumatic diseases, rheumatoid...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::A few years ago, a new method of survival analysis, denoted period analysis, has been developed to derive more up-to-date estimates of long-term survival rates of cancer patients, but this method has rarely been applied so far. Using empirical examples from the Saarland Cancer Registry, we illustrate how seriously tra...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2001-07-01 00:00:00
abstract::This paper presents a tutorial introduction to the handling of uncertainty and decision-making in medical reasoning systems. It focuses on the central role of uncertainty in all of medicine and identifies the major themes that arise in research papers. It then reviews simple Bayesian formulations of the problem and pu...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1995-03-01 00:00:00
abstract:OBJECTIVES:Data collected within the German nosocomial infection surveillance system KISS are recommended as reference data for judging nosocomial infection rates in German intensive care units (ICUs). It is unknown whether the KISS data tend to under- or overestimate the true infection incidence rates. In this article...
journal_title:Methods of information in medicine
pub_type: 杂志文章,多中心研究
doi:
更新日期:2006-01-01 00:00:00
abstract::A rough-sets approach was applied to a data set consisting of animal study results and other compound characteristics to generate local and global (certain/possible) sets of rules for prediction of developmental toxicity in human subjects. A modified version of the rough-sets approach is proposed to allow the construc...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1993-02-01 00:00:00
abstract:OBJECTIVES:Lifestyle has a major influence on the development and progression of atherosclerosis. Our motto for healthy habits is "give up one, reduce two, and increase three". The one thing that is to be given up is smoking. The two things that are to be reduced are intake of food and alcohol. The three things that ar...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVES:In our department, we have been using an Anesthesia Information Management System (AIMS) for five years. In this study, we tested to what extent data extracted from the AIMS could be suitable for the supervision and time-management of operating rooms. METHODS:From 1995 to 1999, all relevant data from 103,26...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:The availability of large amounts of data in heterogeneous formats and the rapid progress in fields such as computer based drug design, medical imaging and medical simulations have lead to a growing demand for large computational power and easy accessibility to heterogeneous data sources. OBJECTIVES:The goa...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::In more and more medical settings, physicians have less and less time to be effective communicators. To be effective, they need accurate, current information about their patients. Tailored health communications can facilitate positive patient-provider communications and foster behavioral changes conducive to health. T...
journal_title:Methods of information in medicine
pub_type: 杂志文章,评审
doi:
更新日期:1998-06-01 00:00:00
abstract::Although arterial mechanical properties have been evaluated using arterial input impedance, the relative difficulty in accurate flow measurement made the value of impedance somewhat limited. To develop an alternative method to evaluate arterial mechanical properties, we analyzed the aortic pressure (AoP)-radial arteri...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVES:The main objective is to show current topics and future trends in the field of medical signal processing which are derived from current research concepts. Signal processing as an integrative concept within the scope of medical informatics is demonstrated. METHODS:For all examples time-variant multivariate a...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVES:A major problem associated with the irradiation of thoracic and abdominal tumors is respiratory motion. In clinical practice, motion compensation approaches are frequently steered by low-dimensional breathing signals (e.g., spirometry) and patient-specific correspondence models, which are used to estimate th...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME13-01-0137
更新日期:2014-01-01 00:00:00
abstract::Informatisation of drug prescription is an important topic in medical informatics. For several years now, computerized drug databases have been implemented. Usually only a small part of the prescriptions can be stored in prescription systems because of the format of the included information; prescriptions contain esse...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1999-03-01 00:00:00
abstract:OBJECTIVES:The main objective of the research is an application of the clustering and cluster validity methods to estimate the number of clusters in cancer tumor datasets. A weighed voting technique is going to be used to improve the prediction of the number of clusters based on different data mining techniques. These ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::Heart rate is known to increase under the influence of increased sympathetic stimulation rates during exertion or stress. Few data are available regarding the rate response to exercise near the fatigue limit, for normal women. The effects on heart rate were studied of fatigue limiting exercise in 87 asymptomatic, norm...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract::Natural language understanding systems have to exploit various kinds of knowledge in order to represent the meaning behind texts. Getting this knowledge in place is often such a huge enterprise that it is tempting to look for systems that can discover such knowledge automatically. We describe how the distinction betwe...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVES:According to results from the epidemiological literature, it can be expected that the prevalence odds ratio (POR) and the prevalence ratio (PR) differ with increasing disease prevalence. We illustrate different concepts to calculate these effect measures in cross-sectional studies and discuss their advantage...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:This article describes the development and evaluation of a distributed user interface (DUI) application to assess visuomotor organization ability. This application enables therapists to evaluate the acquired brain injury (ABI) on patients, and patients, to perform the assessment on a touch screen while thera...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.1055/s-0040-1713086
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVES:To investigate the nonlinear characteristics of visual evoked potentials (VEPs), and their correlation with the visual responses on parvocellular and magnocellular pathways. First and second-order kernels of the VEPs elicited by several checkerboard patterns were estimated, and their relations to the visual ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVES:Our objective is to investigate diabetes-related alteration of glucose control in diurnal fluctuations in normal daily life by detrended fluctuation analysis (DFA). METHODS:The fluctuations of glucose of 12 non-diabetic subjects and 15 diabetic patients were measured using a continuous glucose monitoring sy...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVES:This paper describes a methodology for the monitoring of the fetal cardiac health status during pregnancy, through the effective and non-invasive monitoring of the abdominal ECG signals (abdECG) of the mother. METHODS:For this purpose, a three-stage methodology has been developed. In the first stage, the fe...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME09-01-0041
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:The National Cancer Institute (NCI) has developed the Common Data Elements (CDE) to serve as a controlled vocabulary of data descriptors for cancer research, to facilitate data interchange and inter-operability between cancer research centers. We evaluated CDE's structure to see whether it could represent th...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract:INTRODUCTION:This article is part of the focus theme of Methods of Information in Medicine on "Pervasive Intelligent Technologies for Health". BACKGROUND:This paper addresses the evaluation with hospital staff of an in-patient environment that supports patients, family, nursing staff and medical specialists during the...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME13-02-0032
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:Information systems integration is hard, especially when semantic and business process interoperability requirements need to be met. To succeed, a unified methodology, approaching different aspects of systems architecture such as business, information, computational, engineering and technology viewpoints, has...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME09-02-0012
更新日期:2010-01-01 00:00:00
abstract::In this study, we attempted to discriminate the acceleration signal for horizontal level and stairway walking using wavelet-based fractal analysis method. The acceleration signal was measured close to the center of gravity of the body, while the subjects walked continuously in the corridor and up and down the stairs. ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00