Abstract：
OBJECTIVES:The National Cancer Institute (NCI) has developed the Common Data Elements (CDE) to serve as a controlled vocabulary of data descriptors for cancer research, to facilitate data interchange and inter-operability between cancer research centers. We evaluated CDE's structure to see whether it could represent the elements necessary to support its intended purpose, and whether it could prevent errors and inconsistencies from being accidentally introduced. We also performed automated checks for certain types of content errors that provided a rough measure of curation quality. METHODS:Evaluation was performed on CDE content downloaded via the NCI's CDE Browser, and transformed into relational database form. Evaluation was performed under three categories: 1) compatibility with the ISO/IEC 11179 metadata model, on which CDE structure is based, 2) features necessary for controlled vocabulary support, and 3) support for a stated NCI goal, set up of data collection forms for cancer research. RESULTS:Various limitations were identified both with respect to content (inconsistency, insufficient definition of elements, redundancy) as well as structure--particularly the need for term and relationship support, as well as the need for metadata supporting the explicit representation of electronic forms that utilize sets of common data elements. CONCLUSIONS:While there are numerous positive aspects to the CDE effort, there is considerable opportunity for improvement. Our recommendations include review of existing content by diverse experts in the cancer community; integration with the NCI thesaurus to take advantage of the latter's links to nationally used controlled vocabularies, and various schema enhancements required for electronic form support.
journal_name
Methods Inf Medjournal_title
Methods of information in medicineauthors
Nadkarni PM,Brandt CAsubject
Has Abstractpub_date
2006-01-01 00:00:00pages
594-601issue
6eissn
0026-1270issn
2511-705Xpii
06060594journal_volume
45pub_type
杂志文章abstract：:Psych Topix is a knowledge-based program which guides the clinician from an on-line clinical report to a search of the psychiatric literature or of other relevant databases. It provides this guidance by using an outline of key topics in a clinical field to provide "concept-based" links. Each topic is augmented with an...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1992-09-01 00:00:00
abstract：OBJECTIVES:Our objective is to investigate diabetes-related alteration of glucose control in diurnal fluctuations in normal daily life by detrended fluctuation analysis (DFA). METHODS:The fluctuations of glucose of 12 non-diabetic subjects and 15 diabetic patients were measured using a continuous glucose monitoring sy...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVES:To assess the relevance of various potential confounding factors (comorbidities, obesity, body position, ECG lead, respiratory event type and sleep stage) on the detectability of sleep-related breathing disorders from the ECG. METHODS:A set of 140 simultaneous recordings of polysomnograms and 8-channel Holt...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME17-02-0005
更新日期：2018-05-01 00:00:00
abstract：:A method is described to process and interpret multi-channel bioelectrical signals. The bioelectrical signals were recorded noninvasively over the body surface of human subjects at 120 sites. The body surface Laplacian maps were then constructed from the multi-channel bioelectrical potential measurement. The method wa...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
abstract：OBJECTIVES:We examine the potential of archetype patterns for upper-level ontology development in health information systems (HISs). METHODS:Archetype patterns, based on the integration of archetype concepts and design patterns, are conceptualized and developed for ontology in the HIS domain. The UML provides the unde...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME0519
更新日期：2011-01-01 00:00:00
abstract：:BRAINDEX (Brain-Death Expert System) is an interactive, knowledge-based expert system offering support to physicians in decision making concerning brain death. The physician is given the possibility of communicating in almost natural language and, therefore, in terms with which he is familiar. This updated version of ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1990-07-01 00:00:00
abstract：:A huge amount of medical information is available on the Internet for both experts and laypersons. These resources are frequently used to answer current medical questions and are thus likely to influence the behavior of the users. Criteria for assessing the quality of medical Internet resources have been established b...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1999-06-01 00:00:00
abstract：OBJECTIVE:Introducing the Special Topic of Methods of Information in Medicine on pervasive healthcare, with selected papers from the Pervasive Healthcare Conference at Tampere, Finland, January 30 to February 1, 2008. METHODS:Describing pervasive healthcare as field. Reporting about the content of the selected papers ...
journal_title：Methods of information in medicine
pub_type： 社论
doi：
更新日期：2008-01-01 00:00:00
abstract：:A non-parametric method is presented for modelling nonlinear dynamic mechanisms of respiratory sinus arrhythmia (RSA) in anesthesia caused by positive pressure ventilation. RR interval sequences are shown with Tsay's linearity test to contain both short-term and long-term nonlinear components, which cannot completely ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：OBJECTIVES:The International Medical Informatics Association (IMIA) today is an inclusive organization that represents the medical and health informatics world through its multiple member countries as well as affiliate, corporate and academic institutions, plus working groups and regions. The IMIA leadership deemed thi...
journal_title：Methods of information in medicine
pub_type： 社论
doi：
更新日期：2006-01-01 00:00:00
abstract：:Human event-related potentials reflect cognitive processing, and are normally elicited by external events, such as acoustic sounds or visual stimuli. As such they provide an opportunity to study normal and abnormal brain function noninvasively, at sub-second resolution. Advances in multimedia technology permit special...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2001-07-01 00:00:00
abstract：OBJECTIVE:Record linkage of patient data originating from various data sources and record linkage for checking uniqueness of patient registration are common tasks for every cancer registry. In Austria, there is no unique person identifier in use in the medical system. Hence, it was necessary and the goal of this work t...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVES:Both open- and closed-loop models of beat-to-beat cardiovascular control have been suggested. We tested whether the modelling yields different results with real data while assessing cardiopulmonary and baroreflex gains. METHODS:Two autoregressive models are described to resolve causal relationships between ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVES:In the field of open electronic health records (EHRs), openEHR as an archetype-based approach is being increasingly recognised. It is the objective of this paper to shortly describe this approach, and to analyse how openEHR archetypes impact on health professionals and semantic interoperability. METHODS:Ana...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.1160/ME5001
更新日期：2007-01-01 00:00:00
abstract：:During the last decade there has been a wealth of papers discussing the development of scoring systems in medicine, some of which have led to fully operational computer-aided diagnostic systems. In this paper we sketch the development of a simple scoring system for one of the more common rheumatic diseases, rheumatoid...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：OBJECTIVES:As a preliminary for the design of Computer-Based Patient Records, the aim of this paper is to build an understanding of the roles physical artifacts like paper-based patient records play in supporting cognition and collaboration in the health-care settings. METHOD:A small ethnographically-informed study wa...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVES:To investigate the nonlinear characteristics of visual evoked potentials (VEPs), and their correlation with the visual responses on parvocellular and magnocellular pathways. First and second-order kernels of the VEPs elicited by several checkerboard patterns were estimated, and their relations to the visual ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:The central control of the autonomic nervous system (ANS) and the complex interplay of its components can be described by a functional integrated mode - the central autonomic network (CAN). CAN represents the integrated functioning and interaction between the central nervous system (CNS) and ANS (parasympath...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME17-02-0002
更新日期：2018-05-01 00:00:00
abstract：:Rapid development of community health information networks raises the issue of semantic interoperability between distributed and heterogeneous systems. Indeed, operational health information systems originate from heterogeneous teams of independent developers and have to cooperate in order to exchange data and service...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1998-11-01 00:00:00
abstract：OBJECTIVE:To draw a parallel between the challenges by which a research department in biomedical informatics is confronted and those of a symphony orchestra; in both areas different disciplines and various groups of instruments can be discerned. METHOD:Retrospective, personal review of how to conduct biomedical resear...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:Questions like 'How is your health? How are you feeling? How have you been?' now can be answered in a different way due to innovative health self-quantification apps and devices. These apps and devices generate data that enable individuals to be informed and more responsible about their own health. OBJECTIV...
journal_title：Methods of information in medicine
pub_type： 杂志文章,评审
doi：10.3414/ME15-02-0007
更新日期：2017-01-09 00:00:00
abstract：OBJECTIVES:This study aimed at gaining comprehensive information on the current status of patient care and management applications used in German acute hospitals. Since the degree of ICT coverage in hospitals depends on the attitude of the key decision makers we also wanted to capture their plans and priorities and her...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVES:Hospital information systems (HIS) are the hospital's nervous system. The HIS are mostly grown over several years, dedicated to specific needs and comprise individual workarounds. Changes to such complex systems may cause a variety of differ-ent negative side-effects. In order to understand the nature of inc...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME9220
更新日期：2009-01-01 00:00:00
abstract：OBJECTIVES:Biomedical ontologies exist to serve integration of clinical and experimental data, and it is critical to their success that they be put to widespread use in the annotation of data. How, then, can ontologies achieve the sort of user-friendliness, reliability, cost-effectiveness, and breadth of coverage that ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME9302
更新日期：2010-01-01 00:00:00
abstract：:This paper presents a tutorial introduction to the handling of uncertainty and decision-making in medical reasoning systems. It focuses on the central role of uncertainty in all of medicine and identifies the major themes that arise in research papers. It then reviews simple Bayesian formulations of the problem and pu...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：:In this paper we describe LIED (Liver: Information, Education and Diagnosis), a diagnostic expert system devoted to medical education in the field of hepatology. LIED combines the facilities of a traditional expert system for clinical diagnosis with several modules designed for educational purposes. The goal of such m...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1992-11-01 00:00:00
abstract：:Many clinics are interested to use software packages in daily practice, but lack of integration of such packages seriously limits their scope. In practice this often entails switching between programs and interrupting the run of an individual program. A multi-task approach would not solve this problem as it would not ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1992-02-01 00:00:00
abstract：BACKGROUND:The UMLS assigns semantic types to all its integrated concepts. The semantic types are widely used in various natural language processing tasks in the biomedical domain, such as named entity recognition, semantic disambiguation, and semantic annotation. Due to the size of the UMLS, erroneous semantic type as...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME17-01-0120
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVES:As millions of consumers perform health information retrieval online, the mismatch between their terminology and the terminologies of the information sources could become a major barrier to successful retrievals. To address this problem, we studied the characteristics of consumer terminology for health infor...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：OBJECTIVE:To explain the common conformance and interoperability testing requirements of eHealth applications through two case studies; one using a prominent eHealth messaging standard, namely HL7 v3 [1], and the other using Integrating the Healthcare Enterprise (IHE) [2] Profiles and to describe how these testing requ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME09-02-0022
更新日期：2010-01-01 00:00:00
