Abstract：
:A problem of identifying the phase response curve of the myocardial pacemaker was investigated using a simple dynamic system model of cardiac arrhythmia. A hybrid optimization method of a genetic algorithm and a local optimization technique was employed to obtain a solution of the model fitting. The method was applied to two categories of arrhythmias, ventricular parasystole and high-degree AV block. The present study offered a new insight into the mechanism of cardiac arrhythmias.
journal_name
Methods Inf Medjournal_title
Methods of information in medicineauthors
Ikeda N,Takayanagi K,Takeuchi A,Nara Y,Miyahara Hsubject
Has Abstractpub_date
1997-12-01 00:00:00pages
286-9issue
4-5eissn
0026-1270issn
2511-705Xpii
97040286journal_volume
36pub_type
杂志文章abstract：:A compartmental model for the simulation of in-vivo insulin-like growth factor one (IGF-I) kinetics and metabolism is presented. The model is based on the concept that IGF binding proteins (IGFBPs) act as a reservoir for IGF-I in plasma, thereby restricting its access to the extravascular space. The model is divided i...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1994-12-01 00:00:00
abstract：OBJECTIVES:This paper describes a methodology for the monitoring of the fetal cardiac health status during pregnancy, through the effective and non-invasive monitoring of the abdominal ECG signals (abdECG) of the mother. METHODS:For this purpose, a three-stage methodology has been developed. In the first stage, the fe...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME09-01-0041
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVES:The concept of our system is not only to manage material flows, but also to provide an integrated management resource, a means of correcting errors in medical treatment, and applications to EBM (evidence-based medicine) through the data mining of medical records. METHODS:Prior to the development of this sys...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:ICD is used for coding medical diagnoses across the world, but there is no globally accepted coding system for health care procedures. The need for the introduction of a common international medical procedure classification has been addressed by the Australian NCCH, which proposed the International Classific...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME09-01-0007
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND:Studying workflow is a critical step in designing, implementing and evaluating informatics interventions in complex sociotechnical settings, such as hospital emergency departments (EDs). Known approaches to studying workflow in clinical settings attend to the activities of individual clinicians, thus being i...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME12-01-0079
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVES:To find discriminative combination of influential factors of Intracerebral hematoma (ICH) to cluster ICH patients with similar features to explore relationship among influential factors and 30-day mortality of ICH. METHODS:The data of ICH patients are collected. We use a decision tree to find discriminative...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME15-01-0137
更新日期：2016-10-17 00:00:00
abstract：OBJECTIVES:In this study, we evaluated the internal validity of EPICON, an application for grouping ICPC-coded diagnoses from electronic medical records into episodes of care. These episodes are used to estimate morbidity rates in general practice. METHODS:Morbidity rates based on EPICON were compared to a gold standa...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：UNLABELLED:The HL7 Clinical Document Architecture (CDA) is an important XML-based standard for the representation of clinical documents. OBJECTIVES:The use of Markup Languages could satisfy the demands of involved healthcare staff as well as the needs of patients, to receive an overview of the patient's treatment duri...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVES:In the field of open electronic health records (EHRs), openEHR as an archetype-based approach is being increasingly recognised. It is the objective of this paper to shortly describe this approach, and to analyse how openEHR archetypes impact on health professionals and semantic interoperability. METHODS:Ana...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.1160/ME5001
更新日期：2007-01-01 00:00:00
abstract：:While natural language processing systems are beginning to see clinical use, it remains unclear whether they can be disseminated effectively through the health care community. MedLEE, a general-purpose natural language processor developed for Columbia-Presbyterian Medical Center, was compared to physicians' ability to...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：OBJECTIVES:Data collected within the German nosocomial infection surveillance system KISS are recommended as reference data for judging nosocomial infection rates in German intensive care units (ICUs). It is unknown whether the KISS data tend to under- or overestimate the true infection incidence rates. In this article...
journal_title：Methods of information in medicine
pub_type： 杂志文章,多中心研究
doi：
更新日期：2006-01-01 00:00:00
abstract：OBJECTIVES:To provide a comprehensive bottom-up categorization of model-based segmentation techniques that allows to select, implement, and apply well-suited active contour models for segmentation of medical images, where major challenges are the high variability in shape and appearance of objects, noise, artifacts, pa...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:Main requirements for an Anesthesia Information Management System (AIMS) are the supply of additional information for the anesthesiologist at his workstation and complete documentation of the anesthetic procedure. With the implementation of an AIMS (NarkoData) and effective user support, the quality of documentation a...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2000-12-01 00:00:00
abstract：OBJECTIVES:According to results from the epidemiological literature, it can be expected that the prevalence odds ratio (POR) and the prevalence ratio (PR) differ with increasing disease prevalence. We illustrate different concepts to calculate these effect measures in cross-sectional studies and discuss their advantage...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:With rapid change in health care requiring greater emphasis on productivity and quality management, occupational health hazards in hospitals have been receiving increasing recognition, now not only focusing on controlling infection, but also on chemical, physical, mechanical as well as psychosocial hazards. Reducing c...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1998-06-01 00:00:00
abstract：OBJECTIVE:Information systems integration is hard, especially when semantic and business process interoperability requirements need to be met. To succeed, a unified methodology, approaching different aspects of systems architecture such as business, information, computational, engineering and technology viewpoints, has...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME09-02-0012
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND:The cause-of-death register at the Southern Urals Biophysics Institute (SUBI), Ozyorsk, Russia, was established to document the number and causes of deaths in the Mayak workers cohort, which includes all persons (N = 22,377) employed at Mayak nuclear facility between 1948 and 1982. Most workers were occupati...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME11-01-0049
更新日期：2012-01-01 00:00:00
abstract：OBJECTIVES:A low rate of newly developed pressure ulcers is considered as an important quality indicator in nursing. However, the result of a hospital depends not only on the quality of care but on the risk profile of its patients as well. Therefore, based on multiple logistic regression models we describe a method for...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME10-01-0019
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVES:Electroencephalographic burst activity characteristic of burst-suppression pattern (BSP) in sedated patients and of burst-interburst pattern (BIP) in the quiet sleep of healthy neonates have similar linear and non-linear signal properties. Strong interrelations between a slow frequency component and rhythmic...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVES:The huge amount of released medical apps prevents medical app users from believing that medical scientific societies and other accreditation bodies as well, have the resources and the power for assigning to any medical app a quality score. By the time being, any medical app user has to take the risks related...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME13-01-0093
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVES:Due to the high complexity of structures and processes in health care, thorough systems analyses in health care run the risk of becoming very complex and difficult to handle. Therefore, we aimed to support systematic systems analysis in health care by developing a comprehensive framework that presents and de...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：OBJECTIVES:The aim of this project is to develop a catalogue of competency-based learning objectives "Medical Informatics" for undergraduate medical education (abbreviated NKLM-MI in German). METHODS:The development followed a multi-level annotation and consensus process. For each learning objective a reason why a phy...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME13-04-0001
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:Questions like 'How is your health? How are you feeling? How have you been?' now can be answered in a different way due to innovative health self-quantification apps and devices. These apps and devices generate data that enable individuals to be informed and more responsible about their own health. OBJECTIV...
journal_title：Methods of information in medicine
pub_type： 杂志文章,评审
doi：10.3414/ME15-02-0007
更新日期：2017-01-09 00:00:00
abstract：:The relationship was studied between the increase in oxygen uptake (VO2) measured breath-by-breath at the mouth, and the increase in femoral artery blood flow measured continuously with pulsed and echo Doppler methods. Five men exercised at 50 W on a knee extension ergometer in both the supine and the upright posture....
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
abstract：OBJECTIVES:Biomedical ontologies exist to serve integration of clinical and experimental data, and it is critical to their success that they be put to widespread use in the annotation of data. How, then, can ontologies achieve the sort of user-friendliness, reliability, cost-effectiveness, and breadth of coverage that ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME9302
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVE:To present a geometric ruler to determine predictive values of binary diagnostic test results from prevalence, sensitivity and specificity without calculation. METHODS:On logarithmic scale the relationships between pre-/post-test odds and the likelihood ratio as well as sensitivity, specificity and the likel...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME14-01-0091
更新日期：2015-01-01 00:00:00
abstract：:This paper is concerned with a comparison of two broad classes of mathematical models, additive and multiplicative, for selecting the best among a number of competing project proposals addressed to a defined research objective. The analysis is predicated on the view that, though additive models are widely utilized, th...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1989-07-01 00:00:00
abstract：:The PHOENIX Radiology Consultant is a rule-based expert system which assists physicians in planning radiological work-up strategies. This article describes the methods used to create and validate the system's knowledge base. The feasibility and acceptability of PHOENIX were tested for two years in a clinical trial. Du...
journal_title：Methods of information in medicine
pub_type： 临床试验,杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：:This paper presents a tutorial introduction to the handling of uncertainty and decision-making in medical reasoning systems. It focuses on the central role of uncertainty in all of medicine and identifies the major themes that arise in research papers. It then reviews simple Bayesian formulations of the problem and pu...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：:Pathfinder is an expert system that assists surgical pathologists with the diagnosis of lymph-node diseases. The program is one of a growing number of normative expert systems that use probability and decision theory to acquire, represent, manipulate, and explain uncertain medical knowledge. In this article, we descri...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
