Drop the Likelihood Ratio. A Novel Non-electronic Tool for Interpreting Diagnostic Test Results.

Abstract:

OBJECTIVE:To present a geometric ruler to determine predictive values of binary diagnostic test results from prevalence, sensitivity and specificity without calculation. METHODS:On logarithmic scale the relationships between pre-/post-test odds and the likelihood ratio as well as sensitivity, specificity and the likelihood ratio appear as simple linear (additive) equations. RESULTS:Each of these additive equations can be solved geometrically in form of a ruler with three scales. By amalgamation we devise a novel non-electronic tool which omits the intermediate step of likelihood ratio determination. CONCLUSIONS:We propose a simple geometric method to aid in interpretation of diagnostic test results for both practical and educational purposes.

journal_name

Methods Inf Med

authors

Herich L,Lehmacher W,Hellmich M

doi

10.3414/ME14-01-0091

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

283-7

issue

3

eissn

0026-1270

issn

2511-705X

pii

14-01-0091

journal_volume

54

pub_type

杂志文章
  • Reconstructing bifurcation diagrams of dynamical systems using measured time series.

    abstract::We present an algorithm for reconstructing the bifurcation structure of a dynamical system from time series. The method consists in finding a parameterized predictor function whose bifurcation structure is similar to that of the given system. Nonlinear autoregressive (NAR) models with polynomial terms are employed as ...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Bagarinao E,Pakdaman K,Nomura T,Sato S

    更新日期:2000-06-01 00:00:00

  • Toward a formalization of the process to select IMIA Yearbook best papers.

    abstract:BACKGROUND:Each year, the International Medical Informatics Association Yearbook recognizes significant scientific papers, labelled as "best papers", published the previous year in the subfields of biomedical informatics that correspond to the different section topics of the journal. For each section, about fifteen pre...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:10.3414/ME14-01-0031

    authors: Lamy JB,Séroussi B,Griffon N,Kerdelhué G,Jaulent MC,Bouaud J

    更新日期:2015-01-01 00:00:00

  • HEALTH WATCH: health promotion and disease prevention in primary care.

    abstract::HEALTH WATCH, a longitudinal prospective study of healthy aging, was designed to characterize a healthy population of 2,200 men and women, ages 20-80 years in 1970. Biochemical, hematological, and physiological tests are performed annually over three weekly visits, combined with a self-administered HEALTH WATCH questi...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Schmidt RM

    更新日期:1993-04-01 00:00:00

  • Systems analysis in health care: framework and example.

    abstract:OBJECTIVES:Due to the high complexity of structures and processes in health care, thorough systems analyses in health care run the risk of becoming very complex and difficult to handle. Therefore, we aimed to support systematic systems analysis in health care by developing a comprehensive framework that presents and de...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Ammenwerth E,Ehlers F,Eichstädter R,Haux R,Pohl U,Resch F

    更新日期:2002-01-01 00:00:00

  • Estimating the number of clusters in DNA microarray data.

    abstract:OBJECTIVES:The main objective of the research is an application of the clustering and cluster validity methods to estimate the number of clusters in cancer tumor datasets. A weighed voting technique is going to be used to improve the prediction of the number of clusters based on different data mining techniques. These ...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Bolshakova N,Azuaje F

    更新日期:2006-01-01 00:00:00

  • The Common Data Elements for cancer research: remarks on functions and structure.

    abstract:OBJECTIVES:The National Cancer Institute (NCI) has developed the Common Data Elements (CDE) to serve as a controlled vocabulary of data descriptors for cancer research, to facilitate data interchange and inter-operability between cancer research centers. We evaluated CDE's structure to see whether it could represent th...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Nadkarni PM,Brandt CA

    更新日期:2006-01-01 00:00:00

  • Estimating respiratory pattern variability by symbolic dynamics.

    abstract:OBJECTIVES:The traditional techniques of data analysis are often not sufficient to characterize the complex dynamics of respiration. In this study the respiratory pattern variability was analyzed using symbolic dynamics. METHODS:A group of 20 patients on weaning trials from mechanical ventilation were studied at two d...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Caminal P,Mateu J,Vallverdú M,Giraldo B,Benito S,Voss A

    更新日期:2004-01-01 00:00:00

  • When are additive models valid for evaluating proposed research?

    abstract::This paper is concerned with a comparison of two broad classes of mathematical models, additive and multiplicative, for selecting the best among a number of competing project proposals addressed to a defined research objective. The analysis is predicated on the view that, though additive models are widely utilized, th...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Bunch DS,Cardús D,Fuhrer MJ,Thrall RM

    更新日期:1989-07-01 00:00:00

  • Body surface Laplacian mapping of bioelectrical activity.

    abstract::A method is described to process and interpret multi-channel bioelectrical signals. The bioelectrical signals were recorded noninvasively over the body surface of human subjects at 120 sites. The body surface Laplacian maps were then constructed from the multi-channel bioelectrical potential measurement. The method wa...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: He B,Yu X,Wu D,Mehdi N

    更新日期:1997-12-01 00:00:00

  • Development of ICF code selection tools for mental health care.

    abstract:BACKGROUND:The International Classification of Functioning, Disability and Health (ICF) has been available as a means of coding life functions but the coding process is cumbersome due to the large number of ICF codes. In the current study, we developed ICF code selection tools to support the coding of activity and part...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:10.3414/ME10-01-0062

    authors: Manabe S,Miura Y,Takemura T,Ashida N,Nakagawa R,Mineno T,Matsumura Y

    更新日期:2011-01-01 00:00:00

  • In vivo and simulation study of artificial ventilation effects on energetic variables in cardiosurgical patients.

    abstract:OBJECTIVES:The analysis of energetic ventricular variable changes during artificial ventilation, obtained by numerical simulation was done. Twenty-one sets of hemodynamic parameters for eight cardiosurgical patients were used to estimate left and right stroke work. The data were collected for three methods of ventilati...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: De Lazzari C,Darowski M,Wolski P,Ferrari G,Tosti G,Pisanelli DM

    更新日期:2005-01-01 00:00:00

  • Integrating quantitative and qualitative methods in patient care information system evaluation: guidance for the organizational decision maker.

    abstract:OBJECTIVE:The aim of this paper is twofold. First, we describe two important dimensions of patient care information systems (PCIS) evaluation: the domain of evaluation and the different phases of the PCIS implementation. Second, we claim that, though Randomized Controlled Trials (RCTs) are often still seen as the stand...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Stoop AP,Berg M

    更新日期:2003-01-01 00:00:00

  • The distinction between linguistic and conceptual semantics in medical terminology and its implication for NLP-based knowledge acquisition.

    abstract::Natural language understanding systems have to exploit various kinds of knowledge in order to represent the meaning behind texts. Getting this knowledge in place is often such a huge enterprise that it is tempting to look for systems that can discover such knowledge automatically. We describe how the distinction betwe...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Ceusters W,Buekens F,De Moor G,Waagmeester A

    更新日期:1998-11-01 00:00:00

  • Heart rate response to exercise in normal women.

    abstract::Heart rate is known to increase under the influence of increased sympathetic stimulation rates during exertion or stress. Few data are available regarding the rate response to exercise near the fatigue limit, for normal women. The effects on heart rate were studied of fatigue limiting exercise in 87 asymptomatic, norm...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Bowyer AF,Thomas RA,Bowyer SR

    更新日期:1993-04-01 00:00:00

  • Graphical non-linear representation of multi-dimensional laboratory measurements in their clinical context.

    abstract::A polygon-based graphical representation of laboratory test results using nonlinear scaling is described. It is argued that the nonlinearity of the scale and the use of colors in the representation facilitates interpretation of the test result in its relationship to the standard reference range and critical clinical d...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Hoeke JO,Gelsema ES,Wulkan RW,Leijnse B

    更新日期:1991-04-01 00:00:00

  • Value of scatter-graphs for the assessment of ECG computer measurement results.

    abstract::A new method is presented, different from usual methods, for the discussion of the results of computer ECG measurement programs, based on a new graphical evaluation method. The proposed "scatter-graphs" both highlight the main program results and facilitate the comparison between various wave-recognition algorithms. T...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Morlet D,Rubel P,Willems JL

    更新日期:1990-09-01 00:00:00

  • Evaluation of general practice computer templates. Lessons from a pilot randomised controlled trial.

    abstract::We conducted a pilot randomised trial of computerised templates for the management of asthma and diabetes in general practice in six general practices in North London. Uptake of the guidelines by general practitioners and practice nurses was assessed using qualitative (semi-structured interviews designed to assess the...

    journal_title:Methods of information in medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Tai SS,Nazareth I,Donegan C,Haines A

    更新日期:1999-09-01 00:00:00

  • Building a comprehensive clinical information system from components. The approach at Intermountain Health Care.

    abstract:OBJECTIVES:To discuss the advantages and disadvantages of an interfaced approach to clinical information systems architecture. METHODS:After many years of internally building almost all components of a hospital clinical information system (HELP) at Intermountain Health Care, we changed our architectural approach as we...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Clayton PD,Narus SP,Huff SM,Pryor TA,Haug PJ,Larkin T,Matney S,Evans RS,Rocha BH,Bowes WA 3rd,Holston FT,Gundersen ML

    更新日期:2003-01-01 00:00:00

  • Uncertainty and decisions in medical informatics.

    abstract::This paper presents a tutorial introduction to the handling of uncertainty and decision-making in medical reasoning systems. It focuses on the central role of uncertainty in all of medicine and identifies the major themes that arise in research papers. It then reviews simple Bayesian formulations of the problem and pu...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Szolovits P

    更新日期:1995-03-01 00:00:00

  • Analysis of acceleration signals using wavelet transform.

    abstract::In this study, we attempted to discriminate the acceleration signal for horizontal level and stairway walking using wavelet-based fractal analysis method. The acceleration signal was measured close to the center of gravity of the body, while the subjects walked continuously in the corridor and up and down the stairs. ...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Sekine M,Tamura T,Akay M,Togawa T,Fukui Y

    更新日期:2000-06-01 00:00:00

  • Development of a scoring system to assist in the diagnosis of rheumatoid arthritis.

    abstract::During the last decade there has been a wealth of papers discussing the development of scoring systems in medicine, some of which have led to fully operational computer-aided diagnostic systems. In this paper we sketch the development of a simple scoring system for one of the more common rheumatic diseases, rheumatoid...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Rigby AS

    更新日期:1991-01-01 00:00:00

  • Optimising Health Informatics Outcomes--Getting Good Evidence to Where it Matters.

    abstract::This editorial is part of a For-Discussion-Section of Methods of Information in Medicine about the paper "Evidence-based Health informatics: How do we know what we know?", written by Elske Ammenwerth [1]. Health informatics uses and applications have crept up on health systems over half a century, starting as simple a...

    journal_title:Methods of information in medicine

    pub_type: 评论,社论

    doi:10.3414/ME14-10-0139

    authors: Rigby M

    更新日期:2015-01-01 00:00:00

  • More up-to-date monitoring of long-term survival rates by cancer registries: an empirical example.

    abstract::A few years ago, a new method of survival analysis, denoted period analysis, has been developed to derive more up-to-date estimates of long-term survival rates of cancer patients, but this method has rarely been applied so far. Using empirical examples from the Saarland Cancer Registry, we illustrate how seriously tra...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Brenner H,Gefeller O,Stegmaier C,Ziegler H

    更新日期:2001-07-01 00:00:00

  • Adaptive Designs with Discrete Test Statistics and Consideration of Overrunning.

    abstract:BACKGROUND:Interim analyses are used in clinical trials in order to enable early decisions for medical, ethical, and economic reasons. However, it appears unfeasible to stop a trial during such an interim analysis. New patients will thus enter the trial while the interim analysis is ongoing. Moreover, depending on the ...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:10.3414/ME14-02-0023

    authors: Schmidt R,Burkhardt B,Faldum A

    更新日期:2015-01-01 00:00:00

  • Estimation of arterial mechanical properties from aortic and tonometric arterial pressure waveforms.

    abstract::Although arterial mechanical properties have been evaluated using arterial input impedance, the relative difficulty in accurate flow measurement made the value of impedance somewhat limited. To develop an alternative method to evaluate arterial mechanical properties, we analyzed the aortic pressure (AoP)-radial arteri...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Sugimachi M,Kawada T,Shishido T,Matsumoto N,Alexander J Jr,Sunagawa K

    更新日期:1997-12-01 00:00:00

  • Automatic knowledge acquisition from MEDLINE.

    abstract::Construction of medical knowledge bases for use in expert systems is an arduous task. We propose a procedure for obtaining medical knowledge via automated analysis of citations found in the National Library of Medicine's MEDLINE database. In this method, simple pattern of keywords and subheading co-occurrences are det...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Cimino JJ,Barnett GO

    更新日期:1993-04-01 00:00:00

  • A survey on visual information search behavior and requirements of radiologists.

    abstract:OBJECTIVES:The main objective of this study is to learn more on the image use and search requirements of radiologists. These requirements will then be taken into account to develop a new search system for images and associated meta data search in the Khresmoi project. METHODS:Observations of the radiology workflow, ca...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:10.3414/ME11-02-0025

    authors: Markonis D,Holzer M,Dungs S,Vargas A,Langs G,Kriewel S,Müller H

    更新日期:2012-01-01 00:00:00

  • Survival analysis with time-varying relative risks: a tree-based approach.

    abstract::A tree-based method for estimating time-varying effects of baseline patient characteristics on survival is introduced. A Cox-type model for censored survival data is used in which the time-varying relative risks are modelled as piecewise constants. The tree method consists of three steps: 1. Growing the tree, in which...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Xu R,Adak S

    更新日期:2001-05-01 00:00:00

  • Long-range correlated glucose fluctuations in diabetes.

    abstract:OBJECTIVES:Our objective is to investigate diabetes-related alteration of glucose control in diurnal fluctuations in normal daily life by detrended fluctuation analysis (DFA). METHODS:The fluctuations of glucose of 12 non-diabetic subjects and 15 diabetic patients were measured using a continuous glucose monitoring sy...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Ogata H,Tokuyama K,Nagasaka S,Ando A,Kusaka I,Sato N,Goto A,Ishibashi S,Kiyono K,Struzik ZR,Yamamoto Y

    更新日期:2007-01-01 00:00:00

  • Professional competence and computer literacy in e-age, focus on healthcare.

    abstract:OBJECTIVES:The healthcare sector is facing an enormous acceleration due to the emergence of new knowledge, drugs, devices and diseases. Professional competence, continuing education, service excellence and patient benefits can be facilitated by the developments in information and computer technology--computer literacy ...

    journal_title:Methods of information in medicine

    pub_type: 杂志文章

    doi:

    authors: Stepánková O,Engová D

    更新日期:2006-01-01 00:00:00