Abstract:
:Validation of expert system knowledge bases has proved to be difficult. This paper presents a description of a system called ScriptGen that generates test data for validating the knowledge base of the ONCOCIN cancer therapy planning system. Because of the size and complexity of the ONCOCIN knowledge base, we require tools for automated validation. ScriptGen, which applies techniques developed in testing both traditional software and expert systems, uses a parallel model of the ONCOCIN knowledge base and its own inference engine to generate test cases. We derived the limits of the system from a study that seeded errors into an existing knowledge base.
journal_name
Methods Inf Medjournal_title
Methods of information in medicineauthors
Shwe MA,Tu SW,Fagan LMsubject
Has Abstractpub_date
1989-01-01 00:00:00pages
36-50issue
1eissn
0026-1270issn
2511-705Xpii
89010036journal_volume
28pub_type
杂志文章abstract::A Bayesian decision support system was developed for the diagnosis of rheumatic disorders. Knowledge in this system is represented as evidential weights of findings. Simple weights were calculated as the logarithm of likelihood ratios on the basis of 1,000 consecutive patients from a rheumatological clinic. The effect...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1991-08-01 00:00:00
abstract:OBJECTIVE:Record linkage of patient data originating from various data sources and record linkage for checking uniqueness of patient registration are common tasks for every cancer registry. In Austria, there is no unique person identifier in use in the medical system. Hence, it was necessary and the goal of this work t...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::Rapid development of community health information networks raises the issue of semantic interoperability between distributed and heterogeneous systems. Indeed, operational health information systems originate from heterogeneous teams of independent developers and have to cooperate in order to exchange data and service...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1998-11-01 00:00:00
abstract::It is estimated that, in Japan, several million people suffer from urinary incontinence caused by, e.g., cerebrovascular disease, abdominal operations, spinal-cord damage, etc. Urinary incontinence is said to be a 'hidden' disease. When no adequate treatment is given, a serious situation may arise for both patients an...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract:OBJECTIVES:To assess the impact of a CPOE system on medication-related communication of nurses and physicians. METHODS:In six internal medicine wards of an academic medical center, two questionnaires were used to evaluate nurses' attitudes toward the impact of a paper-based medication system and then a CPOE system on ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME0572
更新日期:2009-01-01 00:00:00
abstract::A rough-sets approach was applied to a data set consisting of animal study results and other compound characteristics to generate local and global (certain/possible) sets of rules for prediction of developmental toxicity in human subjects. A modified version of the rough-sets approach is proposed to allow the construc...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1993-02-01 00:00:00
abstract:OBJECTIVES:The purpose of this work is to develop a health information platform connecting most health facilities in the Rhône-Alpes region. The health platform called SIS-RA is used through a Web interface. An iconic interface is dedicated to the platform and presents information in a unique way for all users. METHOD...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::While the design of a fully general procedure for semantico-pragmatic interpretation of natural language texts does not seem to be feasible with current scientific knowledge and technology, the more practical microworld based approaches lack generality and portability. A compromise between generality and practicality ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1995-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of a lexico-syntactic pattern (LSP) matching method for ontology enrichment using clinical documents. METHODS:Two domains were separately studied using the same methodology. We used radiology documents to enrich RadLex and pathology documents to enrich National Cancer Institute ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME10-01-0020
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Traditional rehabilitation sessions are often a slow, tedious, disempowering and non-motivational process, supported by clinical assessment tools, i.e. evaluation scales that are prone to subjective rating and imprecise interpretation of patient's performance. Poor patient motivation and insufficient accurac...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME16-02-0013
更新日期:2017-03-23 00:00:00
abstract::For use in system development, a method based on both qualitative and quantitative data was employed to study the difficulties--the dilemmas--a general practitioner (GP) faces during daily consultations. Video recordings were used for stimulated recall of the consultation. From 46 consultations, 262 dilemmas were iden...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Tumor documentation is an important task for both clinical research and patient care. Documentation systems for these purposes have to be planned systematically and should be goal oriented. We applied the method of a so-called 'standardized documentation protocol' for systematically planning two documentation systems ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract:OBJECTIVES:Several researchers have proposed the use of logical ontologies as 'reference terminologies'. However, there are a number of unresolved issues. This article describes the development of a logical ontology for nursing interventions and presents the results of evaluation. METHODS:Initially this study involved...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVES:To contribute a new perspective on recent investigations into the scientific foundations of medical informatics (MI) and bioinformatics (BI). To support efforts that could generate synergies and new research directions. METHODS:MI and BI are compared and contrasted from a philosophy of science perspective. ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::Differential Interference Contrast (DIC) microscopy is a powerful visualization tool used to study live biological cells. Its use, however, has been limited to qualitative observations. The inherent non-linear relation between the object properties and the image intensity makes quantitative analysis difficult. As a fi...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:Multi-class molecular cancer classification has great potential clinical implications. Such applications require statistical methods to accurately classify cancer types with a small subset of genes from thousands of genes in the data. OBJECTIVES:This paper presents a new functional gradient descent boosting...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME11-02-0020
更新日期:2012-01-01 00:00:00
abstract::A new method is presented, different from usual methods, for the discussion of the results of computer ECG measurement programs, based on a new graphical evaluation method. The proposed "scatter-graphs" both highlight the main program results and facilitate the comparison between various wave-recognition algorithms. T...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1990-09-01 00:00:00
abstract:OBJECTIVES:In the field of open electronic health records (EHRs), openEHR as an archetype-based approach is being increasingly recognised. It is the objective of this paper to shortly describe this approach, and to analyse how openEHR archetypes impact on health professionals and semantic interoperability. METHODS:Ana...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.1160/ME5001
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To discuss the consequences for medical informatics in encouraging and advancing the development of information processing methodology (IPM) and information and communication technology (ICT) to contribute to high-quality and efficient health care. METHODS:Characterization of the current state of ICT, commen...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::HEALTH WATCH, a longitudinal prospective study of healthy aging, was designed to characterize a healthy population of 2,200 men and women, ages 20-80 years in 1970. Biochemical, hematological, and physiological tests are performed annually over three weekly visits, combined with a self-administered HEALTH WATCH questi...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract:OBJECTIVE:To intensify the collaboration between WHO, the World Health Organization, and IMIA, the International Medical Informatics Association. METHODS:Identifying key areas of collaboration and publishing a joint communiqué during Medinfo 2007 in Brisbane, Australia. RESULTS AND CONCLUSIONS:WHO and IMIA have ident...
journal_title:Methods of information in medicine
pub_type: 社论
doi:10.1160/me5006
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:The UMLS assigns semantic types to all its integrated concepts. The semantic types are widely used in various natural language processing tasks in the biomedical domain, such as named entity recognition, semantic disambiguation, and semantic annotation. Due to the size of the UMLS, erroneous semantic type as...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME17-01-0120
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Studying workflow is a critical step in designing, implementing and evaluating informatics interventions in complex sociotechnical settings, such as hospital emergency departments (EDs). Known approaches to studying workflow in clinical settings attend to the activities of individual clinicians, thus being i...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME12-01-0079
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:The central control of the autonomic nervous system (ANS) and the complex interplay of its components can be described by a functional integrated mode - the central autonomic network (CAN). CAN represents the integrated functioning and interaction between the central nervous system (CNS) and ANS (parasympath...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME17-02-0002
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVES:We discuss supervised classification techniques applied to medical diagnosis based on gene expression profiles. Our focus lies on strategies of adaptive model selection to avoid overfitting in high-dimensional spaces. METHODS:We introduce likelihood-based methods, classification trees, support vector machin...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::Natural language understanding systems have to exploit various kinds of knowledge in order to represent the meaning behind texts. Getting this knowledge in place is often such a huge enterprise that it is tempting to look for systems that can discover such knowledge automatically. We describe how the distinction betwe...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVES:According to results from the epidemiological literature, it can be expected that the prevalence odds ratio (POR) and the prevalence ratio (PR) differ with increasing disease prevalence. We illustrate different concepts to calculate these effect measures in cross-sectional studies and discuss their advantage...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVES:To assess the effects of a CPOE system on inter-professional workflow in the medication process. METHODS:Twenty-three semi-structured interviews with physicians, nurses, and pharmacists were conducted in a Dutch academic hospital. In addition, the handwritten and system-generated documents used daily were c...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME0631
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:The main objective of this study is to learn more on the image use and search requirements of radiologists. These requirements will then be taken into account to develop a new search system for images and associated meta data search in the Khresmoi project. METHODS:Observations of the radiology workflow, ca...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME11-02-0025
更新日期:2012-01-01 00:00:00
abstract::Heart rate is known to increase under the influence of increased sympathetic stimulation rates during exertion or stress. Few data are available regarding the rate response to exercise near the fatigue limit, for normal women. The effects on heart rate were studied of fatigue limiting exercise in 87 asymptomatic, norm...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00