Abstract：
INTRODUCTION:This article is part of the Focus Theme of METHODS of Information in Medicine on "Managing Interoperability and Complexity in Health Systems". BACKGROUND:Data sharing and integration between the clinical research data management system and the electronic health record system remains a challenging issue. To approach the issue, there is emerging interest in utilizing the Detailed Clinical Model (DCM) approach across a variety of contexts. The Intermountain Healthcare Clinical Element Models (CEMs) have been adopted by the Office of the National Coordinator awarded Strategic Health IT Advanced Research Projects for normalization (SHARPn) project for normalizing patient data from the electronic health records (EHR). OBJECTIVE:The objective of the present study is to describe our preliminary efforts toward harmonization of the SHARPn CEMs with CDISC (Clinical Data Interchange Standards Consortium) clinical study data standards. METHODS:We were focused on three generic domains: demographics, lab tests, and medications. We performed a panel review on each data element extracted from the CDISC templates and SHARPn CEMs. RESULTS:We have identified a set of data elements that are common to the context of both clinical study and broad secondary use of EHR data and discussed outstanding harmonization issues. CONCLUSIONS:We consider that the outcomes would be useful for defining new requirements for the DCM modeling community and ultimately facilitating the semantic interoperability between systems for both clinical study and broad secondary use domains.
journal_name
Methods Inf Medjournal_title
Methods of information in medicineauthors
Jiang G,Evans J,Oniki TA,Coyle JF,Bain L,Huff SM,Kush RD,Chute CGdoi
10.3414/ME13-02-0019subject
Has Abstractpub_date
2015-01-01 00:00:00pages
65-74issue
1eissn
0026-1270issn
2511-705Xpii
13-02-0019journal_volume
54pub_type
杂志文章abstract：OBJECTIVES:We discuss supervised classification techniques applied to medical diagnosis based on gene expression profiles. Our focus lies on strategies of adaptive model selection to avoid overfitting in high-dimensional spaces. METHODS:We introduce likelihood-based methods, classification trees, support vector machin...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVE:Record linkage may create powerful datasets with which investigators can conduct comparative effectiveness studies evaluating the impact of tests or interventions on health. All linkages of health care data files to date have used protected health information (PHI) in their linkage variables. A technique to l...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME14-01-0093
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVES:The authors' aim was to investigate the representations, wishes, and fears of family caregivers (FCs) regarding 14 innovative technologies (IT) for care aiding and burden alleviation, given the severe physical and psychological stress induced by dementia care, and the very slow uptake of these technologies i...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:Information processing in hospitals, especially in university hospitals, is currently faced with two major issues: low-cost hardware and progress in networking technology leads to a further decentralization of computing capacity, due to the increasing need for information processing in hospitals and due to economic re...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1995-09-01 00:00:00
abstract：:We present an algorithm for reconstructing the bifurcation structure of a dynamical system from time series. The method consists in finding a parameterized predictor function whose bifurcation structure is similar to that of the given system. Nonlinear autoregressive (NAR) models with polynomial terms are employed as ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：OBJECTIVES:Describe how the HL7 Clinical Document Architecture (CDA), a foundational standard in US Meaningful Use, contributes to a "big data, incrementally structured" interoperability strategy, whereby data structured incrementally gets large amounts of data flowing faster. We present cases showing how this approach...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME14-01-0030
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVES:A low rate of newly developed pressure ulcers is considered as an important quality indicator in nursing. However, the result of a hospital depends not only on the quality of care but on the risk profile of its patients as well. Therefore, based on multiple logistic regression models we describe a method for...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME10-01-0019
更新日期：2010-01-01 00:00:00
abstract：:The use of computers in the health sector has increased significantly during the last few years in Nigeria. This paper addresses the integration of health and informatics education, or health education and informatics education, or informatics education in health care delivery. It gives an introduction to the status o...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1997-02-01 00:00:00
abstract：:Continuous recording of intraluminal pressures for extended periods of time is currently regarded as a valuable method for detection of esophageal motor abnormalities. A subsequent automatic analysis of the resulting motility data relies on strict mathematical criteria for recognition of pressure events. Due to great ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：OBJECTIVES:The huge amount of released medical apps prevents medical app users from believing that medical scientific societies and other accreditation bodies as well, have the resources and the power for assigning to any medical app a quality score. By the time being, any medical app user has to take the risks related...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME13-01-0093
更新日期：2014-01-01 00:00:00
abstract：:A polygon-based graphical representation of laboratory test results using nonlinear scaling is described. It is argued that the nonlinearity of the scale and the use of colors in the representation facilitates interpretation of the test result in its relationship to the standard reference range and critical clinical d...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：BACKGROUND:The barbell squat is a popularly used lower limb rehabilitation exercise. It is also an integral exercise in injury risk screening protocols. To date athlete/patient technique has been assessed using expensive laboratory equipment or subjective clinical judgement; both of which are not without shortcomings. ...
journal_title：Methods of information in medicine
pub_type： 临床试验,杂志文章
doi：10.3414/ME16-01-0141
更新日期：2017-10-26 00:00:00
abstract：OBJECTIVES:According to results from the epidemiological literature, it can be expected that the prevalence odds ratio (POR) and the prevalence ratio (PR) differ with increasing disease prevalence. We illustrate different concepts to calculate these effect measures in cross-sectional studies and discuss their advantage...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVES:The analysis of energetic ventricular variable changes during artificial ventilation, obtained by numerical simulation was done. Twenty-one sets of hemodynamic parameters for eight cardiosurgical patients were used to estimate left and right stroke work. The data were collected for three methods of ventilati...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：BACKGROUND:The availability of large amounts of data in heterogeneous formats and the rapid progress in fields such as computer based drug design, medical imaging and medical simulations have lead to a growing demand for large computational power and easy accessibility to heterogeneous data sources. OBJECTIVES:The goa...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVES:Biomedical ontologies exist to serve integration of clinical and experimental data, and it is critical to their success that they be put to widespread use in the annotation of data. How, then, can ontologies achieve the sort of user-friendliness, reliability, cost-effectiveness, and breadth of coverage that ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME9302
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVES:GTDS is a documentation system used by more than 40 German hospital cancer registries. This paper discusses the factors that contributed to its success concerning design, development, and routine use. METHODS:Success is measured in terms of the system's financial independence of public grants and its succes...
journal_title：Methods of information in medicine
pub_type： 杂志文章,评审
doi：
更新日期：2006-01-01 00:00:00
abstract：:In more and more medical settings, physicians have less and less time to be effective communicators. To be effective, they need accurate, current information about their patients. Tailored health communications can facilitate positive patient-provider communications and foster behavioral changes conducive to health. T...
journal_title：Methods of information in medicine
pub_type： 杂志文章,评审
doi：
更新日期：1998-06-01 00:00:00
abstract：OBJECTIVES:Personal digital assistants (PDAs) are in widespread use by resident physicians in many countries, reaching as high as 95% in some reports. Uses are varied and include clinical decision support and support of evidence-based practice. Utilization by resident doctors in Japan has not been characterized. This s...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME0607
更新日期：2009-01-01 00:00:00
abstract：OBJECTIVES:The traditional techniques of data analysis are often not sufficient to characterize the complex dynamics of respiration. In this study the respiratory pattern variability was analyzed using symbolic dynamics. METHODS:A group of 20 patients on weaning trials from mechanical ventilation were studied at two d...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVES:As a preliminary for the design of Computer-Based Patient Records, the aim of this paper is to build an understanding of the roles physical artifacts like paper-based patient records play in supporting cognition and collaboration in the health-care settings. METHOD:A small ethnographically-informed study wa...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVE:Introducing the Special Topic of Methods of Information in Medicine on pervasive healthcare, with selected papers from the Pervasive Healthcare Conference at Tampere, Finland, January 30 to February 1, 2008. METHODS:Describing pervasive healthcare as field. Reporting about the content of the selected papers ...
journal_title：Methods of information in medicine
pub_type： 社论
doi：
更新日期：2008-01-01 00:00:00
abstract：:The AVA program combines a thirty-year history with an approach that remains innovative; namely: multivariate statistical analysis on orthogonal ECG leads. Its diagnostic reference base includes only diagnoses independently verified by non-ECG criteria. The diagnostic module assesses probabilities of nine alternative ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1990-09-01 00:00:00
abstract：OBJECTIVES:To assess the relevance of various potential confounding factors (comorbidities, obesity, body position, ECG lead, respiratory event type and sleep stage) on the detectability of sleep-related breathing disorders from the ECG. METHODS:A set of 140 simultaneous recordings of polysomnograms and 8-channel Holt...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME17-02-0005
更新日期：2018-05-01 00:00:00
abstract：:A new method is presented, different from usual methods, for the discussion of the results of computer ECG measurement programs, based on a new graphical evaluation method. The proposed "scatter-graphs" both highlight the main program results and facilitate the comparison between various wave-recognition algorithms. T...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1990-09-01 00:00:00
abstract：BACKGROUND:Radiology reports are a permanent record of patient's health information often used in clinical practice and research. Reading radiology reports is common for clinicians and radiologists. However, it is laborious and time-consuming when the amount of reports to be read is large. Assisting clinicians to locat...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.1055/s-0039-1694992
更新日期：2019-09-01 00:00:00
abstract：:HEALTH WATCH, a longitudinal prospective study of healthy aging, was designed to characterize a healthy population of 2,200 men and women, ages 20-80 years in 1970. Biochemical, hematological, and physiological tests are performed annually over three weekly visits, combined with a self-administered HEALTH WATCH questi...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1993-04-01 00:00:00
abstract：:Reliable record linkage is a prerequisite for high-quality population-based disease registration. Rapid developments in computer processing have made record linkage both more efficient and more reliable in recent years. At the same time, concerns about confidentiality increasingly hinder record linkage in many disease...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：OBJECTIVE:Record linkage of patient data originating from various data sources and record linkage for checking uniqueness of patient registration are common tasks for every cancer registry. In Austria, there is no unique person identifier in use in the medical system. Hence, it was necessary and the goal of this work t...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVES:To contribute a new perspective on recent investigations into the scientific foundations of medical informatics (MI) and bioinformatics (BI). To support efforts that could generate synergies and new research directions. METHODS:MI and BI are compared and contrasted from a philosophy of science perspective. ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
