Abstract：
:Appropriateness and necessity research of various procedures in medicine may be the most complex field of innovation in healthcare and technology assessment. Nevertheless, the appropriateness of the indication of any medical intervention is probably more important than the outcome since even ideal quality components of structures, processes and outcomes become irrelevant without a proper indication. The first part of our appropriateness initiative in interventional cardiology and gynecology was to formulate guidelines. To define the appropriateness for coronary angiography, coronary revascularization and hysterectomy, literature-based consensus methods were used. The second part was to disseminate the guidelines in a user-friendly manner via the Internet. Therefore, we relied on a system-driven query facility for propositional (experts) rules. The next part of the appropriateness initiative may be a user-friendly Internet-based data collection system to validate the national accepted guidelines. Most important may be that only data that is needed can be collected using a refined database technology. The described Second Opinion System can be found under: http:sos.inf.ethz.ch. Research on indications with data on clinical outcome may open new opportunities to validate indication guidelines using Internet/database technology for data analysis and browsing of decision graphs concerning clinical decision-making. This new technology facilitates the evaluation of appropriateness and necessity criteria in combination with clinical outcomes.
journal_name
Methods Inf Medjournal_title
Methods of information in medicineauthors
Schilling J,Faisst K,Kapetanios E,Wyss P,Norrie MC,Gutzwiller Fkeywords:
subject
Has Abstractpub_date
2000-08-01 00:00:00pages
233-7issue
3eissn
0026-1270issn
2511-705Xpii
00030233journal_volume
39pub_type
杂志文章abstract：OBJECTIVE:We have been developing a decision support system that uses electronic clinical data and provides alerts to clinicians. However, the inference rules for such a system are difficult to write in terms of representing domain concepts and temporal reasoning. To address this problem, we have developed an ontology-...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME9126
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND:The cause-of-death register at the Southern Urals Biophysics Institute (SUBI), Ozyorsk, Russia, was established to document the number and causes of deaths in the Mayak workers cohort, which includes all persons (N = 22,377) employed at Mayak nuclear facility between 1948 and 1982. Most workers were occupati...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME11-01-0049
更新日期：2012-01-01 00:00:00
abstract：:Based on personal experiences, observations are offered on health information in developing countries, ways in which information systems can be strengthened, and opportunities for health-information science graduates. Although data collection consumes a significant portion of the health worker's day, information syste...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1994-06-01 00:00:00
abstract：OBJECTIVE:To present a geometric ruler to determine predictive values of binary diagnostic test results from prevalence, sensitivity and specificity without calculation. METHODS:On logarithmic scale the relationships between pre-/post-test odds and the likelihood ratio as well as sensitivity, specificity and the likel...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME14-01-0091
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVES:EEG scalp potential distributions recorded in humans are affected by low spatial resolution and by the dependence on the electrical reference used. High resolution EEG technologies are available to drastically increase the spatial resolution of the raw EEG. Such technologies include the computation of surfac...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：BACKGROUND:For the statistical analysis of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) data, compartment models are a commonly used tool. By these models, the observed uptake of contrast agent in some tissue over time is linked to physiologic properties like capillary permeability and blood flow. Up ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME14-01-0131
更新日期：2016-01-01 00:00:00
abstract：:A rough-sets approach was applied to a data set consisting of animal study results and other compound characteristics to generate local and global (certain/possible) sets of rules for prediction of developmental toxicity in human subjects. A modified version of the rough-sets approach is proposed to allow the construc...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1993-02-01 00:00:00
abstract：BACKGROUND:Each year, the International Medical Informatics Association Yearbook recognizes significant scientific papers, labelled as "best papers", published the previous year in the subfields of biomedical informatics that correspond to the different section topics of the journal. For each section, about fifteen pre...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME14-01-0031
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVES:Benchmarking statements provide a mechanism for making academic standards explicit within a subject area. They allow comparisons between courses to be based on learning outcomes rather than by defining a curriculum. No such statement has been produced for informatics. In the absence of any established benchm...
journal_title：Methods of information in medicine
pub_type： 杂志文章,评审
doi：10.1160/me0442
更新日期：2007-01-01 00:00:00
abstract：:Reliable record linkage is an essential component of the quality of population-based disease registration. Quality assessment of disease registries should, therefore, include quantitative approaches to describe the extent of record-linkage errors. The homonym and synonym rates have been proposed for this purpose. The ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1996-03-01 00:00:00
abstract：:The use of computers in the field of medical education is common. Our purpose is to present a Computer-Assisted Instruction system which has been developed over ten years at the University of Compiègne and the University of Rennes Medical School. This system can be used to help the student to solve clinical cases by a...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1994-10-01 00:00:00
abstract：BACKGROUND:Interim analyses are used in clinical trials in order to enable early decisions for medical, ethical, and economic reasons. However, it appears unfeasible to stop a trial during such an interim analysis. New patients will thus enter the trial while the interim analysis is ongoing. Moreover, depending on the ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME14-02-0023
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVES:To discuss the advantages and disadvantages of an interfaced approach to clinical information systems architecture. METHODS:After many years of internally building almost all components of a hospital clinical information system (HELP) at Intermountain Health Care, we changed our architectural approach as we...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVES:Electroencephalographic burst activity characteristic of burst-suppression pattern (BSP) in sedated patients and of burst-interburst pattern (BIP) in the quiet sleep of healthy neonates have similar linear and non-linear signal properties. Strong interrelations between a slow frequency component and rhythmic...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVES:This paper aims to present an activity-theoretical method for studying the effects of user participation in IS development. METHODS:This method is developed through a case study of the process of designing a diabetes database. RESULTS AND CONCLUSIONS:The method consists of a historical analysis of the desi...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVES:The aim of this project is to develop a catalogue of competency-based learning objectives "Medical Informatics" for undergraduate medical education (abbreviated NKLM-MI in German). METHODS:The development followed a multi-level annotation and consensus process. For each learning objective a reason why a phy...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME13-04-0001
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVES:We discuss supervised classification techniques applied to medical diagnosis based on gene expression profiles. Our focus lies on strategies of adaptive model selection to avoid overfitting in high-dimensional spaces. METHODS:We introduce likelihood-based methods, classification trees, support vector machin...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：BACKGROUND:The single leg squat (SLS) is a common lower limb rehabilitation exercise. It is also frequently used as an evaluative exercise to screen for an increased risk of lower limb injury. To date athlete / patient SLS technique has been assessed using expensive laboratory equipment or subjective clinical judgement...
journal_title：Methods of information in medicine
pub_type： 临床试验,杂志文章
doi：10.3414/ME16-02-0002
更新日期：2017-03-23 00:00:00
abstract：OBJECTIVES:This paper describes a methodology for the monitoring of the fetal cardiac health status during pregnancy, through the effective and non-invasive monitoring of the abdominal ECG signals (abdECG) of the mother. METHODS:For this purpose, a three-stage methodology has been developed. In the first stage, the fe...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME09-01-0041
更新日期：2010-01-01 00:00:00
abstract：:In this study, we attempted to discriminate the acceleration signal for horizontal level and stairway walking using wavelet-based fractal analysis method. The acceleration signal was measured close to the center of gravity of the body, while the subjects walked continuously in the corridor and up and down the stairs. ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：OBJECTIVES:Both open- and closed-loop models of beat-to-beat cardiovascular control have been suggested. We tested whether the modelling yields different results with real data while assessing cardiopulmonary and baroreflex gains. METHODS:Two autoregressive models are described to resolve causal relationships between ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVES:In the field of open electronic health records (EHRs), openEHR as an archetype-based approach is being increasingly recognised. It is the objective of this paper to shortly describe this approach, and to analyse how openEHR archetypes impact on health professionals and semantic interoperability. METHODS:Ana...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.1160/ME5001
更新日期：2007-01-01 00:00:00
abstract：:Four tabular and two graphical techniques for the presentation of laboratory test results were evaluated in a reaction time experiment with 25 volunteers. Artificial variables and values were used to represent sets of 12 laboratory tests to eliminate the possible effects of clinical experience. Analyses focused on fou...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:Psych Topix is a knowledge-based program which guides the clinician from an on-line clinical report to a search of the psychiatric literature or of other relevant databases. It provides this guidance by using an outline of key topics in a clinical field to provide "concept-based" links. Each topic is augmented with an...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1992-09-01 00:00:00
abstract：BACKGROUND:In the past decade, Medical Informatics (MI) and Bioinformatics (BI) have converged towards a new discipline, called Biomedical Informatics (BMI) bridging informatics methods across the spectrum from genomic research to personalized medicine and global healthcare. This convergence still raises challenging re...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME11-01-0060
更新日期：2012-01-01 00:00:00
abstract：INTRODUCTION:This article is part of the Focus Theme of METHODS of Information in Medicine on "Managing Interoperability and Complexity in Health Systems". BACKGROUND:Data sharing and integration between the clinical research data management system and the electronic health record system remains a challenging issue. T...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME13-02-0019
更新日期：2015-01-01 00:00:00
abstract：:Surgical fluid replacement is a critical issue in medicine as the fluid volume excess or deficit can both complicate the patient's condition. Currently, the administration of fluid volume is carried out primarily based on the experience and expertise of the anaesthetist as there is no analytical method available to es...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2001-03-01 00:00:00
abstract：OBJECTIVES:A low rate of newly developed pressure ulcers is considered as an important quality indicator in nursing. However, the result of a hospital depends not only on the quality of care but on the risk profile of its patients as well. Therefore, based on multiple logistic regression models we describe a method for...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME10-01-0019
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVES:Combination of multiple testing and modeling techniques in dose-response studies. Use of hypotheses tests to assess the significance of the dose-response signal associated with a given candidate dose-response model. Estimation of target dose(s) following the previous model selection step. Illustration of the...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:A Bayesian decision support system was developed for the diagnosis of rheumatic disorders. Knowledge in this system is represented as evidential weights of findings. Simple weights were calculated as the logarithm of likelihood ratios on the basis of 1,000 consecutive patients from a rheumatological clinic. The effect...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
