Abstract：
OBJECTIVES:Cerebral ventricular volume has the potential to become an important parameter in quantitative neurological diagnosis. However, no accepted methodology for routine clinical use exists to date. We sought a robust, reproducible, and fast technique to evaluate cerebral ventricular volume in young children. METHODS:We describe a novel volumetric methodology to segment and visualize intracerebral fluid spaces and to quantify ventricular volumes. The method is based on broadly available T1 weighted volumetric magnetic resonance (MR) imaging, an interactive watershed transform, and a fully automated histogram analysis. We evaluated this volumetric methodology with 34 clinical volumetric MR datasets from non-sedated children (age 6-7 y) with a history of prematurity and low birth weight (< or = 1500 g) obtained during a prospective study. RESULTS:The methodology, with adaptation for small ventricular size, was capable of evaluating all 34 of the pediatric datasets for cerebral ventricular volume. The method was a) robust for normal and pathological anatomy, b) reproducible, c) fast with less than five minutes for image analysis, and d) equally applicable to children and adults. CONCLUSIONS:Clinical brain ventricular volume calculations in non-sedated children can be performed using routine MR imaging besides efficient three-dimensional segmentation and histogram analysis with results that are robust and reproducible.
journal_name
Methods Inf Medjournal_title
Methods of information in medicineauthors
Hahn HK,Millar WS,Klinghammer O,Durkin MS,Tulipano PK,Peitgen HOkeywords:
subject
Has Abstractpub_date
2004-01-01 00:00:00pages
376-82issue
4eissn
0026-1270issn
2511-705Xpii
04040376journal_volume
43pub_type
杂志文章abstract：:Appropriateness and necessity research of various procedures in medicine may be the most complex field of innovation in healthcare and technology assessment. Nevertheless, the appropriateness of the indication of any medical intervention is probably more important than the outcome since even ideal quality components o...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2000-08-01 00:00:00
abstract：:Based on personal experiences, observations are offered on health information in developing countries, ways in which information systems can be strengthened, and opportunities for health-information science graduates. Although data collection consumes a significant portion of the health worker's day, information syste...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1994-06-01 00:00:00
abstract：OBJECTIVES:Biomedical applications, such as analysis and management of mass spectrometry proteomics experiments, involve heterogeneous platforms and knowledge, massive data sets, and complex algorithms. Main requirements of such applications are semantic modeling of the experiments and data analysis, as well as high pe...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：BACKGROUND:Delayed patient recruitment is a common problem in clinical trials. According to the literature, only about a third of medical research studies recruit their planned number of patients within the time originally specified. OBJECTIVES:To provide a method to estimate patient accrual rates in clinical trials b...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME0582
更新日期：2009-01-01 00:00:00
abstract：:In more and more medical settings, physicians have less and less time to be effective communicators. To be effective, they need accurate, current information about their patients. Tailored health communications can facilitate positive patient-provider communications and foster behavioral changes conducive to health. T...
journal_title：Methods of information in medicine
pub_type： 杂志文章,评审
doi：
更新日期：1998-06-01 00:00:00
abstract：OBJECTIVES:Empirical mode decomposition (EMD) is a frequently used signal processing approach which adaptively decomposes a signal into a set of narrow-band components known as intrinsic mode functions (IMFs). For multi-trial, multivariate (multiple simultaneous recordings), and multi-subject analyses the number and si...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME14-02-0024
更新日期：2015-01-01 00:00:00
abstract：:During the last decade there has been a wealth of papers discussing the development of scoring systems in medicine, some of which have led to fully operational computer-aided diagnostic systems. In this paper we sketch the development of a simple scoring system for one of the more common rheumatic diseases, rheumatoid...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Pathfinder is an expert system that assists surgical pathologists with the diagnosis of lymph-node diseases. The program is one of a growing number of normative expert systems that use probability and decision theory to acquire, represent, manipulate, and explain uncertain medical knowledge. In this article, we descri...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
abstract：BACKGROUND:The availability of large amounts of data in heterogeneous formats and the rapid progress in fields such as computer based drug design, medical imaging and medical simulations have lead to a growing demand for large computational power and easy accessibility to heterogeneous data sources. OBJECTIVES:The goa...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:Reliable record linkage is an essential component of the quality of population-based disease registration. Quality assessment of disease registries should, therefore, include quantitative approaches to describe the extent of record-linkage errors. The homonym and synonym rates have been proposed for this purpose. The ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1996-03-01 00:00:00
abstract：:A Bayesian decision support system was developed for the diagnosis of rheumatic disorders. Knowledge in this system is represented as evidential weights of findings. Simple weights were calculated as the logarithm of likelihood ratios on the basis of 1,000 consecutive patients from a rheumatological clinic. The effect...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
abstract：:Artificial neural networks (ANNs) are compared to standard statistical methods for outcome prediction in biomedical problems. A general method for using genetic algorithms to "evolve" ANN architecture (EANN) is presented. Accuracy of logistic regression, a fully interconnected ANN, and an EANN for predicting depressio...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1998-09-01 00:00:00
abstract：OBJECTIVES:As a preliminary for the design of Computer-Based Patient Records, the aim of this paper is to build an understanding of the roles physical artifacts like paper-based patient records play in supporting cognition and collaboration in the health-care settings. METHOD:A small ethnographically-informed study wa...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:Informatisation of drug prescription is an important topic in medical informatics. For several years now, computerized drug databases have been implemented. Usually only a small part of the prescriptions can be stored in prescription systems because of the format of the included information; prescriptions contain esse...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1999-03-01 00:00:00
abstract：OBJECTIVES:Electroencephalographic burst activity characteristic of burst-suppression pattern (BSP) in sedated patients and of burst-interburst pattern (BIP) in the quiet sleep of healthy neonates have similar linear and non-linear signal properties. Strong interrelations between a slow frequency component and rhythmic...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVE:Introducing the Special Topic of Methods of Information in Medicine on pervasive healthcare, with selected papers from the Pervasive Healthcare Conference at Tampere, Finland, January 30 to February 1, 2008. METHODS:Describing pervasive healthcare as field. Reporting about the content of the selected papers ...
journal_title：Methods of information in medicine
pub_type： 社论
doi：
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVES:To discuss application areas of information technology in medicine and health care on the occasion of the opening of the Private Universität für Medizinische Informatik und Technik Tirol/University for Health Informatics and Technology Tyrol (UMIT) at Innsbruck, Tyrol, Austria. RESULTS AND CONCLUSIONS:Impor...
journal_title：Methods of information in medicine
pub_type：
doi：
更新日期：2002-01-01 00:00:00
abstract：:A polygon-based graphical representation of laboratory test results using nonlinear scaling is described. It is argued that the nonlinearity of the scale and the use of colors in the representation facilitates interpretation of the test result in its relationship to the standard reference range and critical clinical d...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：:Medical informaticians are multidisciplinary professionals responsible for developing complex technical systems. The aim of this study was to investigate how a code of ethics can help medical informaticians in avoiding design failures. An exploratory case study was performed to identify factors related to failure duri...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：1999-06-01 00:00:00
abstract：OBJECTIVES:This study aimed at gaining comprehensive information on the current status of patient care and management applications used in German acute hospitals. Since the degree of ICT coverage in hospitals depends on the attitude of the key decision makers we also wanted to capture their plans and priorities and her...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVES:The aim of this project is to develop a catalogue of competency-based learning objectives "Medical Informatics" for undergraduate medical education (abbreviated NKLM-MI in German). METHODS:The development followed a multi-level annotation and consensus process. For each learning objective a reason why a phy...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME13-04-0001
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVES:The purpose of this work is to develop a health information platform connecting most health facilities in the Rhône-Alpes region. The health platform called SIS-RA is used through a Web interface. An iconic interface is dedicated to the platform and presents information in a unique way for all users. METHOD...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:The International Classification of Functioning, Disability and Health (ICF) has been available as a means of coding life functions but the coding process is cumbersome due to the large number of ICF codes. In the current study, we developed ICF code selection tools to support the coding of activity and part...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.3414/ME10-01-0062
更新日期：2011-01-01 00:00:00
abstract：OBJECTIVE:To discuss the consequences for medical informatics in encouraging and advancing the development of information processing methodology (IPM) and information and communication technology (ICT) to contribute to high-quality and efficient health care. METHODS:Characterization of the current state of ICT, commen...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：OBJECTIVES:The filtered backprojection is not able to cope with metal-induced inconsistencies in the Radon space which leads to artifacts in reconstructed CT images. A new algorithm is presented that reduces the drawbacks of existing artifact reduction strategies. METHODS:Inconsistent projection data are bridged by di...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：10.1160/ME9041
更新日期：2007-01-01 00:00:00
abstract：:Human event-related potentials reflect cognitive processing, and are normally elicited by external events, such as acoustic sounds or visual stimuli. As such they provide an opportunity to study normal and abnormal brain function noninvasively, at sub-second resolution. Advances in multimedia technology permit special...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2001-07-01 00:00:00
abstract：OBJECTIVES:Both open- and closed-loop models of beat-to-beat cardiovascular control have been suggested. We tested whether the modelling yields different results with real data while assessing cardiopulmonary and baroreflex gains. METHODS:Two autoregressive models are described to resolve causal relationships between ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:Differential Interference Contrast (DIC) microscopy is a powerful visualization tool used to study live biological cells. Its use, however, has been limited to qualitative observations. The inherent non-linear relation between the object properties and the image intensity makes quantitative analysis difficult. As a fi...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：OBJECTIVES:In our department, we have been using an Anesthesia Information Management System (AIMS) for five years. In this study, we tested to what extent data extracted from the AIMS could be suitable for the supervision and time-management of operating rooms. METHODS:From 1995 to 1999, all relevant data from 103,26...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:We present an algorithm for reconstructing the bifurcation structure of a dynamical system from time series. The method consists in finding a parameterized predictor function whose bifurcation structure is similar to that of the given system. Nonlinear autoregressive (NAR) models with polynomial terms are employed as ...
journal_title：Methods of information in medicine
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
