Abstract:
PURPOSE OF REVIEW:To review the literature on toluidine blue (TBlue) and to discuss the utility of TBlue in assessing and in clinical management of patients with oral mucosal lesions. The literature search was conducted using key word search including oral cancer, oral premalignant lesions, and TBlue and by selecting references from the articles reviewed. RECENT FINDINGS:The findings of this review show that TBlue has utility as an adjunct in the detection of premalignant and malignant oral mucosal lesions and in identifying high-risk areas of lesions for biopsy in patients at increased risk of cancer when evaluated by experienced healthcare workers. SUMMARY:TBlue positive lesions, whether histologically benign or with dysplasia, predict molecular change and behavior of oral premalignant lesions. TBlue may provide information regarding lesion margins, accelerate the decision to biopsy, guide biopsy site selection and treatment of oral premalignant and malignant lesions. These findings support the utility of TBlue as a clinical adjunct in assessment of oral mucosal lesions.
journal_name
Curr Opin Otolaryngol Head Neck Surgauthors
Epstein JB,Güneri Pdoi
10.1097/moo.0b013e32832771dasubject
Has Abstractpub_date
2009-04-01 00:00:00pages
79-87issue
2eissn
1068-9508issn
1531-6998journal_volume
17pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:There is an increasing percentage of children with persistent obstructive sleep apnea (OSA) after removal of the tonsils and adenoids (T&A). Although sleep apnea has been an active area of research and treatment in the adult population, our awareness of this problem in children is still in its initial...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e32834c1728
更新日期:2011-12-01 00:00:00
abstract:PURPOSE OF REVIEW:The objective of this article is to assess current newborn hearing screening protocols. We will focus on technologies or modalities used, protocol steps, training of screeners, timing of first screen, and loss to follow-up. A summary of program reports focusing on protocols from Greece, China, South A...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000389
更新日期:2017-10-01 00:00:00
abstract:PURPOSE OF REVIEW:This article reviews the literature on patient adherence to two different approaches to allergen-specific immunotherapy for allergic disease. Factors related to adherence in general, as well as the various methods used to measure adherence, will be discussed. RECENT FINDINGS:Although a complex intera...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e32835f8048
更新日期:2013-06-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to go over the only therapy for olfactory loss supported by level 1a evidence that is currently available, which is olfactory training. This therapy is widely underutilized and has the potential to help many patients with olfactory dysfunction who are otherwise offered no...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000328
更新日期:2017-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Endoscopic sinus surgery became the gold standard in inflammatory disorders of the nose and paranasal sinuses, in cerebrospinal fluid leak and epistaxis management, and established its efficacy in the oncology of the region. However, there are certain limitations which make an external approach mandat...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000219
更新日期:2016-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Facial paralysis often has a significant emotional impact on patients. Along with the myriad of new surgical techniques in managing facial paralysis comes the challenge of selecting the most effective procedure for the patient. This review delineates common surgical techniques and reviews state-of-the...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/01.moo.0000233594.84175.a0
更新日期:2006-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Swallowing disorders impact the health and quality of millions of lives of patients across the age spectrum. The broad scope of the problem is in contrast to the volume of methods that we have to treat the problem. Investigators are testing interventions that go beyond the swallowing system and are ta...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e3282febd4b
更新日期:2008-06-01 00:00:00
abstract:PURPOSE OF REVIEW:Merkel cell carcinoma (MCC) is a rare, aggressive malignancy. Worldwide incidence is increasing and roughly 50% of patients present with a primary lesion in the head and neck. This article discusses recent advances and treatment recommendations. RECENT FINDINGS:Recent research has focused on the carc...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000029
更新日期:2014-04-01 00:00:00
abstract:PURPOSE OF REVIEW:This article will examine recent publications on the endoscopic management of juvenile nasopharyngeal angiofibromas. RECENT FINDINGS:The use of an endoscopic approach to resect small juvenile nasopharyngeal angiofibromas is supported by excellent results from a number of operative series published in...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/01.moo.0000188859.91607.65
更新日期:2006-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Spontaneous nasal cerebrospinal fluid (CSF) leaks represent a distinct clinical entity that presents important diagnostic and therapeutic challenges. Recognition of the proper demographic group and presenting symptoms, as well as the radiologic features of this disease process, are integral to making ...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e328011bc76
更新日期:2007-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Clinical management of asthma is challenging and measuring fractional exhaled nitric oxide (FeNO) can be another tool to assist in meeting this challenge. RECENT FINDINGS:Asthma is a heterogeneous condition. There are many different phenotypes. FeNO can help the physician identify which patients have...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000247
更新日期:2016-06-01 00:00:00
abstract:PURPOSE OF REVIEW:Little is published regarding variations of skull-base anatomy and their relevance to the performance of endoscopic sinus surgery. Several catastrophic complications have occurred in patients with low-lying skull-base variation. This review's purpose is to make the reader aware of skull-base variation...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/00020840-200502000-00006
更新日期:2005-02-01 00:00:00
abstract:PURPOSE OF REVIEW:The goal of cancer screening is to detect tumor at an early stage, and early cancer detection is the hallmark of successful treatment. In addition to traditional tissue biopsy-based diagnostics, more reliable, inexpensive, and noninvasive methods are required for early diagnosis of cancer. In this rev...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000502
更新日期:2019-04-01 00:00:00
abstract:PURPOSE:The purpose of this review is to provide the reader with current information regarding the standards for audiologic assessment of infants and very young children. The nature of the appropriate test battery and the need for adjusting test procedures to meet the specific needs of infants and toddlers are emphasiz...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/00020840-200310000-00012
更新日期:2003-10-01 00:00:00
abstract:PURPOSE OF REVIEW:Swallowing is a vital function and the clearance of the pharynx by deglutition, which removes matter that could be aspirated, and the respiratory phase patterns associated with deglutition are important in protecting the airways and lungs against aspiration. This article reviews swallowing and respira...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章
doi:10.1097/MOO.0000000000000670
更新日期:2020-12-01 00:00:00
abstract:PURPOSE OF REVIEW:This article reviews literature on the facial reanimation technique, from direct facial nerve repair and grafting to neuromuscular-free transplantation. The discussion will focus on the indications of the different approaches based on timing of the facial palsy and on patient's features. RECENT FINDI...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e32834fa744
更新日期:2012-04-01 00:00:00
abstract:PURPOSE OF REVIEW:Chronic rhinosinusitis is a common illness for which systemic antibiotics are frequently prescribed, although high-level evidence for this practice is largely lacking. We review the available literature addressing the proper role of oral antibiotics in the treatment of chronic rhinosinusitis. RECENT ...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e32835ac625
更新日期:2013-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Patients being treated for chronic rhinosinusitis, whether via medical or surgical means, account for a significant percentage of all medical malpractice claims against otolaryngologists. In this study, we present suggestions to help otolaryngologists safeguard against unnecessary claims. RECENT FIND...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000024
更新日期:2014-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Rhinosinusitis is one of the most common medical complaints in the United States, affecting up to 16% of the population. It is associated with over 13 million physician visits per year and an estimated aggregated cost of over $6 billion annually. Patients with chronic rhinosinusitis (CRS) demonstrate ...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e328334f670
更新日期:2010-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Distraction osteogenesis is finding increasing application in the management of mandibular defects. It provides an alternative method of mandibular reconstruction in varied clinical settings, notably following trauma and ablation of malignant tumors. Many recent studies have explored modifications in ...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e3282495925
更新日期:2007-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Surgical approaches to the upper facial skeleton comprise the coronal, lower eyelid and midface degloving approaches. These are routinely employed in both ablative and reconstructive craniofacial procedures. The ability to perform them in a well tolerated and predictable manner is predicated on knowle...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e328347f895
更新日期:2011-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Endoscopic orbital decompression is an ever-evolving surgical procedure with modifications as well as new indications for the procedure. The purpose of this review is to update the reader on optimizing patient selection, surgical timing, highlight the latest modifications to surgical technique and to ...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000326
更新日期:2017-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Microvascular reconstruction for head and neck cancers has improved both cosmesis and functionality of patients undergoing treatment. Many patients have had prior surgery (neck dissection), radiation and/or chemotherapy as part of their management. When microvascular reconstruction is required after p...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e32833a2e50
更新日期:2010-08-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to evaluate medical malpractice involving patients with head and neck cancer. In the United States, problems associated with the medical malpractice environment are reaching proportions that threaten the delivery of health care. RECENT FINDINGS:Several methods to learn m...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/00020840-200404000-00003
更新日期:2004-04-01 00:00:00
abstract:PURPOSE OF REVIEW:Fine needle aspiration is a safe diagnostic technique that is widely employed for lesions of the head and neck. Among head and neck sites, the parotid gland stands apart for the number, diversity and peculiarity of pathologic processes to target this structure. This matchless complexity has prompted a...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/01.moo.0000193184.38310.0a
更新日期:2006-04-01 00:00:00
abstract:PURPOSE OF REVIEW:This review is designed to update the reader on the current state of nasal endoscopy in the control of epistaxis. Recent articles are reviewed and demonstrate recent developments and results. RECENT FINDINGS:The use of endoscopy for control of anterior and posterior epistaxis is beneficial, with less...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/00020840-200402000-00012
更新日期:2004-02-01 00:00:00
abstract:PURPOSE OF REVIEW:The current article reviews the literature on the distribution of nasal irrigation in the treatment of chronic sinusitis, especially in how sinus surgery and irrigation techniques affect its delivery to the nasal cavity and paranasal sinuses. RECENT FINDINGS:Nasal irrigation has become a useful tool ...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000429
更新日期:2018-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Office-based laryngeal laser surgery was created recently and is emerging as a reliable and practical method of treating a number of laryngeal lesions. This style of minimally invasive surgery is becoming increasingly popular in the United States and abroad. RECENT FINDINGS:Fiber-based lasers and dis...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e3281574582
更新日期:2007-06-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of this article is to summarize and put into historical perspective current advances in research in otosclerosis, a disorder of the human temporal bone with a hereditary predisposition that is among the most common causes of acquired hearing loss. RECENT FINDINGS:Genetic studies have revealed...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/01.moo.0000244194.97301.19
更新日期:2006-10-01 00:00:00
abstract:PURPOSE OF REVIEW:To discuss the current indications for ventilation tube placement RECENT FINDINGS:In the past year, several studies have challenged the current guidelines for ventilation tube placement and antibiotic use for otitis media in children. Critics argue that some of these studies have poor scientific vali...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e3283095046
更新日期:2008-10-01 00:00:00