Abstract:
PURPOSE OF REVIEW:The goal of cancer screening is to detect tumor at an early stage, and early cancer detection is the hallmark of successful treatment. In addition to traditional tissue biopsy-based diagnostics, more reliable, inexpensive, and noninvasive methods are required for early diagnosis of cancer. In this review, we highlight some of the recent advancements in the field of salivary diagnostics in oral cancer. RECENT FINDINGS:'Salivaomics' is a broad collection of technologies used to explore different types of molecules contained in saliva. Although many protein and mRNA salivary biomarkers have been identified that can detect oral squamous cell carcinoma (OSCC), none have so far been validated for current clinical use. As the heterogeneity in carcinogenesis and multifactorial cause for OSCC, the most reliable results are gathered with the use of multiple biomarker candidates to improve accuracy and sensitivity of the test used. This further requires sensitive technology to detect salivary biomarkers in low quantities. SUMMARY:Large scale studies that incorporate proteomic, transcriptomic, and additional 'omics,' need to be initiated to bring technology to clinical point-of-care applications.
journal_name
Curr Opin Otolaryngol Head Neck Surgauthors
Aro K,Kaczor-Urbanowicz K,Carreras-Presas CMdoi
10.1097/MOO.0000000000000502subject
Has Abstractpub_date
2019-04-01 00:00:00pages
91-97issue
2eissn
1068-9508issn
1531-6998journal_volume
27pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:This purpose of this article is to review and provide an update of current publications on the evaluation and management of adenoid cystic carcinoma. RECENT FINDINGS:Adenoid cystic carcinoma is an uncommon salivary gland malignancy that presents insidiously and is generally advanced when diagnosed. C...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/00020840-200404000-00013
更新日期:2004-04-01 00:00:00
abstract:PURPOSE OF REVIEW:Office-based laryngeal laser surgery was created recently and is emerging as a reliable and practical method of treating a number of laryngeal lesions. This style of minimally invasive surgery is becoming increasingly popular in the United States and abroad. RECENT FINDINGS:Fiber-based lasers and dis...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e3281574582
更新日期:2007-06-01 00:00:00
abstract:PURPOSE OF REVIEW:Merkel cell carcinoma (MCC) is a rare, aggressive malignancy. Worldwide incidence is increasing and roughly 50% of patients present with a primary lesion in the head and neck. This article discusses recent advances and treatment recommendations. RECENT FINDINGS:Recent research has focused on the carc...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000029
更新日期:2014-04-01 00:00:00
abstract:PURPOSE OF REVIEW:Surgical robotics arose as an extension of virtual reality and robotic technology developed by the United States Department of Defense. Current surgical robotic systems have been used to perform a variety of minimally invasive surgical procedures. RECENT FINDINGS:The Food and Drug Administration rece...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/01.moo.0000122309.13359.af
更新日期:2004-06-01 00:00:00
abstract:PURPOSE OF REVIEW:Clival chordomas are rare malignant tumors associated with a poor prognosis. In this article, we review the current literature to identify a variety of strategies that provide guidelines toward the optimal management for this aggressive tumor. RECENT FINDINGS:Molecular disease, particularly, the deve...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000140
更新日期:2015-04-01 00:00:00
abstract:PURPOSE OF REVIEW:Despite nerve-sparing surgery, postoperative shoulder morbidity remains high and significantly impacts patient's quality of life. This review will focus on recent findings of anatomical nuances of the cranial nerve XI (CN XI) along its course in the neck and possible reasons for postoperative morbidit...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000342
更新日期:2017-04-01 00:00:00
abstract:PURPOSE OF REVIEW:This study is aimed towards clinicians involved in the rapidly developing field of hair restoration. We provide a review of recent literature on this topic. RECENT FINDINGS:Recent studies discussed in this article focus on various aspects of follicular unit transplant surgery, including hairline desi...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e32832da13b
更新日期:2009-08-01 00:00:00
abstract:PURPOSE OF REVIEW:The development of monoclonal antibody-based biologics targeted at inhibition of the Th2 cytokines interleukin-4, interleukin-5 and interleukin-13 represent potentially effective treatments for asthma and allergic diseases. This short review is based on English-language original articles in PubMed or ...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000352
更新日期:2017-06-01 00:00:00
abstract::Since the beginning of humanity, man has sought to define beauty. Whether by philosophy, mathematical constructs, social studies, or biology, the fascination with and the study of beauty has consumed our emotions and intellect. Many myths about this powerful force in our daily lives have been created, and some continu...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/00020840-200308000-00014
更新日期:2003-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Endoscopic orbital decompression is an ever-evolving surgical procedure with modifications as well as new indications for the procedure. The purpose of this review is to update the reader on optimizing patient selection, surgical timing, highlight the latest modifications to surgical technique and to ...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000326
更新日期:2017-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Medical error is a common problem, and its human cost in terms of disability, suffering, and death is stunning. Steps toward reducing medical error will require the identification of mistake-prone practices within a complex health care system. Erroneous pathologic diagnosis has been identified as one ...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/01.moo.0000156162.20789.66
更新日期:2005-04-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to go over the only therapy for olfactory loss supported by level 1a evidence that is currently available, which is olfactory training. This therapy is widely underutilized and has the potential to help many patients with olfactory dysfunction who are otherwise offered no...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000328
更新日期:2017-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Functional rhinoplasty is a term that is commonly used to describe any technique used to address nasal obstruction in the nasal valve region. The cause of nasal valve collapse differs based on the site. Internal valve collapse may be idiopathic or associated with previous rhinoplasty, trauma, or weake...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000172
更新日期:2015-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Endoscopic sinus surgery techniques and technologies have undergone rapid development over the past two decades. Recently, image guided systems have been implemented in endoscopic sinus surgery, carrying the promise of increased safety during surgery. This review compiles available data regarding the ...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e3282fdccad
更新日期:2008-06-01 00:00:00
abstract:PURPOSE OF REVIEW:To discuss the current indications for ventilation tube placement RECENT FINDINGS:In the past year, several studies have challenged the current guidelines for ventilation tube placement and antibiotic use for otitis media in children. Critics argue that some of these studies have poor scientific vali...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e3283095046
更新日期:2008-10-01 00:00:00
abstract:PURPOSE OF REVIEW:Timing of pediatric nasal surgery has always been a controversial topic. Concern over disrupting growing parts of the face and causing permanent facial deformity has led to a primarily conservative approach. Many surgeons feel that it is prudent to wait until the patient has completed nasal growth aft...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000378
更新日期:2017-08-01 00:00:00
abstract:PURPOSE OF REVIEW:This article reviews literature on the facial reanimation technique, from direct facial nerve repair and grafting to neuromuscular-free transplantation. The discussion will focus on the indications of the different approaches based on timing of the facial palsy and on patient's features. RECENT FINDI...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e32834fa744
更新日期:2012-04-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to summarize the recent knowledge on eustachian tube dysfunction and the patulous eustachian tube. RECENT FINDINGS:A clinically useful test for eustachian tube function is still lacking. Narrowing of the isthmus alone was demonstrated to be an insufficient cause of otiti...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/01.moo.0000176465.68128.45
更新日期:2005-10-01 00:00:00
abstract:PURPOSE OF REVIEW:This article aims to review previous research reports and to summarize current strategies for the optimal duration of voice rest and the effect of phonatory stimulation after phonomicrosurgery. RECENT FINDINGS:Voice rest is commonly recommended after laryngeal surgery to prevent worsening of vocal fo...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000407
更新日期:2017-12-01 00:00:00
abstract:PURPOSE OF REVIEW:To review the indications for Mohs micrographic surgery in skin cancer particularly with relationship to tumours of the head and neck and any recent developments which may influence those indications in the near future. RECENT FINDINGS:There is increasing evidence to support the use of Mohs micrograp...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e32833b6f19
更新日期:2010-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Clinical management of asthma is challenging and measuring fractional exhaled nitric oxide (FeNO) can be another tool to assist in meeting this challenge. RECENT FINDINGS:Asthma is a heterogeneous condition. There are many different phenotypes. FeNO can help the physician identify which patients have...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000247
更新日期:2016-06-01 00:00:00
abstract:PURPOSE OF REVIEW:This article reviews the current literature and summarizes the latest developments in screening and early detection of oral cancers and looks at the future possibilities. RECENT FINDINGS:Oral cancer is the best model for screening and prevention. The screening for oral cancer can be population based,...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000237
更新日期:2016-04-01 00:00:00
abstract:PURPOSE OF REVIEW:This review briefly explains the basic facts about nitric oxide, which is entering clinical practice as a measure of lower airways inflammation and is likely also to be employed in otorhinolaryngological practice. RECENT FINDINGS:These include the validity of nasal nitric oxide in diagnosing primary ...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e32825b0763
更新日期:2007-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Recurrent respiratory papillomatosis (RRP) is the most common as well as the costliest benign airway neoplasm in the United States [Ivancic et al. (2018). Laryngoscope Investig Otolaryngol 3:22; Derkay (1995). Arch Otolaryngol Head Neck Surg 121:1386]. In addition, it is potentially deadly, with risk ...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000490
更新日期:2018-12-01 00:00:00
abstract:PURPOSE OF REVIEW:This article reviews literature on the scientific background of functional electric stimulation of the immobile larynx, the status of animal pacing trials, and first clinical attempts to establish laryngeal pacing. RECENT FINDINGS:Impaired vocal fold motion is seen following recurrent laryngeal nerve...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0b013e32834cb7ba
更新日期:2011-12-01 00:00:00
abstract:PURPOSE OF REVIEW:Orbital floor blowout fractures may lead to significant morbidity, including debilitating double vision and globe malposition. Thorough evaluation and timely surgical intervention may prevent long-term sequelae. RECENT FINDINGS:New studies have demonstrated certain patients with orbital floor fractur...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000550
更新日期:2019-08-01 00:00:00
abstract:PURPOSE OF REVIEW:The current review will focus on head and neck reconstructive techniques for the pharyngoesophagus. This article reviews the changing patterns of flap usage and will evaluate the advantages and disadvantages of selected pedicled and free flaps for pharyngoesophageal reconstruction. A number of flaps a...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000081
更新日期:2014-10-01 00:00:00
abstract:PURPOSE OF REVIEW:To describe and popularize the transmanubrial osteomuscular-sparing approach (TOSA) outside its original thoracic surgical field of application, based on the consideration that it could be of interest for the management of a number of head and neck cases in both elective and emergent scenarios. RECEN...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000605
更新日期:2020-04-01 00:00:00
abstract:PURPOSE OF REVIEW:The article reviews the effects of cervical osteophytosis and spine posture on swallowing, and how they can cause dysphagia. RECENT FINDINGS:Cerivical osteophytosis which is a bony overgrowth of the cervical spines, it affects the swallowing through different mechanisms, including direct mechanical c...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/MOO.0000000000000488
更新日期:2018-12-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to evaluate medical malpractice involving patients with head and neck cancer. In the United States, problems associated with the medical malpractice environment are reaching proportions that threaten the delivery of health care. RECENT FINDINGS:Several methods to learn m...
journal_title:Current opinion in otolaryngology & head and neck surgery
pub_type: 杂志文章,评审
doi:10.1097/00020840-200404000-00003
更新日期:2004-04-01 00:00:00