Abstract:
:Acute coronary syndromes (ACS), such as unstable angina, acute myocardial infarction, and sudden cardiac death, are commonly associated with the presence of vulnerable plaques in coronary arteries. Rupture or erosion of vulnerable plaques results in the formation of luminal thrombi due to the physical contact between platelets and thrombogenic elements within the atherosclerotic lesions. Considering the socioeconomic burden of ACS, it is imperative that the scientific community achieves a clear understanding of the multifaceted pathophysiology of vulnerable atheroma to identify accurate prognostic biomarkers and therapeutic targets. The analytical power of modern proteomic technologies could facilitate our understanding of vulnerable plaques and lead to the discovery of novel therapeutic targets and diagnostic biomarkers.
journal_name
Curr Atheroscler Repjournal_title
Current atherosclerosis reportsauthors
Didangelos A,Simper D,Monaco C,Mayr Mdoi
10.1007/s11883-009-0030-xsubject
Has Abstractpub_date
2009-05-01 00:00:00pages
188-95issue
3eissn
1523-3804issn
1534-6242journal_volume
11pub_type
杂志文章,评审abstract::Although the role of implantable cardioverter defibrillator (ICD) and cardiac resynchronization therapy (CRT) in improving outcomes in ischemic cardiomyopathy (ICM) has been described, the data regarding gender-based survival outcomes are limited. There is a higher preponderance of non-ischemic cardiomyopathy (NICM) i...
journal_title:Current atherosclerosis reports
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doi:10.1007/s11883-015-0512-y
更新日期:2015-06-01 00:00:00
abstract::Diabesity is a term often used to indicate the association of type-2 diabetes mellitus (T2DM) with obesity; the prevalence of both conditions is rapidly increasing worldwide and has reached epidemic proportions. Insulin resistance represents the major determinant of T2DM, which becomes manifest once relative β-cell fa...
journal_title:Current atherosclerosis reports
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doi:10.1007/s11883-012-0284-6
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journal_title:Current atherosclerosis reports
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doi:10.1007/s11883-004-0057-y
更新日期:2004-07-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-000-0090-4
更新日期:2000-01-01 00:00:00
abstract::Abdominal aortic aneurysms (AAA) are permanent dilations in the infra-renal area in which the arterial tissue is characterized by inflammation and medial degeneration. AAAs are a common vascular disorder and cause significant mortality in the aged population. Despite the high prevalence of this disease, there is limit...
journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2002-05-01 00:00:00
abstract::Raised plasma triglyceride (TG) levels are an independent risk factor for coronary artery disease (CAD), and thus understanding the genetic and environmental determinants of TG levels are of major importance. TG metabolism is a process for delivering free fatty acids for energy storage or b-oxidation, and involves a n...
journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-001-0061-4
更新日期:2001-05-01 00:00:00
abstract::Plant foods rich in carbohydrate and dietary fiber have many health benefits. One concern often expressed about higher carbohydrate, lower fat diets is that they may increase fasting serum triglycerides. Recently the importance of hypertriglyceridemia as an independent risk factor for coronary heart disease has been r...
journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-000-0055-7
更新日期:2000-11-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-020-00855-7
更新日期:2020-06-23 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2006-07-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-014-0408-2
更新日期:2014-05-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2011-12-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-004-0118-2
更新日期:2004-01-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章
doi:10.1007/s11883-018-0747-5
更新日期:2018-07-05 00:00:00
abstract:PURPOSE OF REVIEW:We aimed to summarize recent guidelines, position papers, and high-quality clinical research relating the use of nutraceuticals in the management of individuals at high risk of atherosclerotic cardiovascular disease. RECENT FINDINGS:It is essential that individuals at high risk of cardiovascular dise...
journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-020-00887-z
更新日期:2020-09-18 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-007-0026-3
更新日期:2007-09-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-016-0573-6
更新日期:2016-05-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-016-0623-0
更新日期:2016-12-01 00:00:00
abstract:PURPOSE OF REVIEW:This review aims to explore the relationship between AF and carotid atherosclerosis, and the impact on the outcomes of cardiovascular and cerebrovascular events. Also, our aim is to critically review current knowledge and delineate future directions for effective treatment or prevention as well as str...
journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-019-0808-4
更新日期:2019-11-29 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-015-0547-0
更新日期:2015-12-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-018-0731-0
更新日期:2018-05-19 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2011-08-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2006-03-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2014-10-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-008-0022-2
更新日期:2008-04-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
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更新日期:2005-02-01 00:00:00
abstract:PURPOSE OF REVIEW:High-intensity exercise may beneficially impact on insulin sensitivity. However, there is still uncertainty on the actual impact of high-intensity interval training (HIIT) on chronic physiologic adaptations among patients with type 2 diabetes mellitus (T2DM). We aimed to systematically search and appr...
journal_title:Current atherosclerosis reports
pub_type: 杂志文章
doi:10.1007/s11883-019-0767-9
更新日期:2019-02-02 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-013-0371-3
更新日期:2013-12-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-000-0045-9
更新日期:2000-11-01 00:00:00
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journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-015-0516-7
更新日期:2015-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Mutations in both nuclear and mitochondrial genes are associated with the development of atherosclerotic lesions in arteries and may provide a partial explanation to the focal nature of lesion distribution in the arterial wall. This review is aimed to discuss the genetic aspects of atherogenesis with ...
journal_title:Current atherosclerosis reports
pub_type: 杂志文章,评审
doi:10.1007/s11883-020-00873-5
更新日期:2020-08-09 00:00:00