Mechanisms of abdominal aortic aneurysm formation.

abstract：PURPOSE OF REVIEW:To summarize epidemiology, pathophysiology, prognostic relevance, and treatment options of coronary artery disease (CAD) when coupled with severe aortic stenosis (SAS). In regard to treatment options, we focused on the most recently adopted therapeutic approaches and on the future perspectives in ligh...

journal_title：Current atherosclerosis reports

authors： Pepe M,Larosa C,Rosa I,Biondi-Zoccai G,Nestola PL,Di Cillo O,Bortone AS,Giordano A,Favale S

更新日期：2020-05-26 00:00:00

abstract：:The thiazolidinediones, acting through peroxisome proliferator-activated receptor chi (PPARchi), affect multiple areas of metabolism. Of increasing importance is the recognition that these agents affect lipoprotein metabolism and cause changes in serum lipid and lipoprotein levels. All three thiazolidinediones, includ...

journal_title：Current atherosclerosis reports

authors： Goldberg RB

更新日期：2006-09-01 00:00:00

abstract：:Recently reported clinical trials raise doubts on the effectiveness of nonstatin lipid-lowering therapies in reducing the residual risk of cardiovascular events after statin monotherapy. Addition of -torcetrapib to statin therapy increased overall mortality in coronary patients despite a marked increase in high-densit...

journal_title：Current atherosclerosis reports

authors： Ansell BJ

更新日期：2009-01-01 00:00:00

abstract：:Diabesity is a term often used to indicate the association of type-2 diabetes mellitus (T2DM) with obesity; the prevalence of both conditions is rapidly increasing worldwide and has reached epidemic proportions. Insulin resistance represents the major determinant of T2DM, which becomes manifest once relative β-cell fa...

journal_title：Current atherosclerosis reports

authors： Castagneto M,Mingrone G

更新日期：2012-12-01 00:00:00

abstract：:Vascular inflammation contributes critically to the initiation and progression of atherosclerosis. These processes are accelerated in hyperglycemia and play key roles in the increased incidence and severity of myocardial infarction and stroke observed in diabetes. Evidence suggests that the ligands of the receptor for...

journal_title：Current atherosclerosis reports

authors： Yan SF,Naka Y,Hudson BI,Herold K,Yan SD,Ramasamy R,Schmidt AM

更新日期：2006-05-01 00:00:00

abstract：:There has been increasing interest in the health benefits of supplemental and/or dietary omega-3 polyunsaturated fatty acids (PUFAs), particularly in their role in disease prevention. This interest escalated once their effects on cardiovascular health were observed from numerous observational studies in populations wh...

journal_title：Current atherosclerosis reports

authors： Fares H,Lavie CJ,DiNicolantonio JJ,O'Keefe JH,Milani RV

更新日期：2014-02-01 00:00:00

abstract：:Peroxisome proliferator-activated receptors (PPARs) are the key transcription factors regulating lipid metabolism and energy homeostasis. PPARalpha and PPARgamma are known therapeutic targets for hypertriglyceridemia and type 2 diabetes, respectively. The physiologic function of the third member, PPARdelta, has been d...

journal_title：Current atherosclerosis reports

authors： Kang K,Hatano B,Lee CH

更新日期：2007-01-01 00:00:00

abstract：:Olive oil is the principal source of fat in the Mediterranean diet, which has been associated with a lower incidence of coronary heart disease and certain cancers. Olive oil is characterized by a high proportion of monounsaturated oleic acid, but the main peculiarity of extra-virgin oil is the presence of remarkable q...

journal_title：Current atherosclerosis reports

authors： Visioli F,Galli C

更新日期：2001-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Coronary artery disease (CAD) is a major cause of morbidity and mortality globally and poses a threat to both men and women across their lifespans. There is accumulating evidence to support that CAD may present differently in women and men, ranging from the clinical presentation, diagnosis, and manage...

journal_title：Current atherosclerosis reports

authors： Madan N,Gajo E,Sanghani RM,Volgman AS

更新日期：2020-06-23 00:00:00

abstract：:Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is a calcium-independent phospholipase A(2) enzyme secreted by leukocytes and associated with circulating low-density lipoprotein and macrophages in atherosclerotic plaques. Until recently, the biological role of Lp-PLA(2) in atherosclerosis was controversial, but ...

journal_title：Current atherosclerosis reports

authors： Chauffe RJ,Wilensky RL,Mohler ER 3rd

更新日期：2010-01-01 00:00:00

abstract：:There is a significant prevalence (20%-80% depending on the population and the study) of lipid disorders and other cardiovascular risk factors in people living with HIV infection. This review focuses on HIV and HIV treatment-associated metabolic and cardiovascular concerns, including dyslipidemias, lipodystrophy syndr...

journal_title：Current atherosclerosis reports

authors： Troll JG

更新日期：2011-02-01 00:00:00

abstract：:Approximately one third of ischemic strokes are labeled cryptogenic because the etiology is unknown despite a thorough evaluation. Paroxysmal atrial fibrillation carries the same risk of ischemic stroke as persistent atrial fibrillation and has increasingly gained attention as a potential source of cryptogenic stroke....

journal_title：Current atherosclerosis reports

authors： Zhang C,Kasner SE

更新日期：2015-12-01 00:00:00

abstract：:Pharmacotherapies with agents that inhibit platelet function have proven to be effective in the treatment of acute coronary syndromes, and in the prevention of complications during and after percutaneous coronary intervention. Because of multiple synergetic pathways of platelet activation and their close interplay wit...

journal_title：Current atherosclerosis reports

authors： Kalra K,Franzese CJ,Gesheff MG,Lev EI,Pandya S,Bliden KP,Tantry US,Gurbel PA

更新日期：2013-12-01 00:00:00

abstract：:The development of multiple diagnostic intracoronary imaging modalities has increased our understanding of coronary atherosclerotic disease. These imaging modalities, intravascular ultrasound (IVUS), optical coherence tomography (OCT), and near-infrared spectroscopy (NIRS), have provided a method to study plaques and ...

journal_title：Current atherosclerosis reports

authors： Hoang V,Grounds J,Pham D,Virani S,Hamzeh I,Qureshi AM,Lakkis N,Alam M

更新日期：2016-09-01 00:00:00

abstract：:Aspirin remains one of the most extensively studied cardiovascular medications in the history of medicine. However, despite multiple, well-designed, large randomized controlled trials evaluating the potential of aspirin to prevent cardiovascular events in individuals without known cardiovascular disease (CVD), the rol...

journal_title：Current atherosclerosis reports

authors： Miedema MD,Huguelet J,Virani SS

更新日期：2016-01-01 00:00:00

abstract：PURPOSE OF REVIEW:High-intensity exercise may beneficially impact on insulin sensitivity. However, there is still uncertainty on the actual impact of high-intensity interval training (HIIT) on chronic physiologic adaptations among patients with type 2 diabetes mellitus (T2DM). We aimed to systematically search and appr...

journal_title：Current atherosclerosis reports

authors： da Silva DE,Grande AJ,Roever L,Tse G,Liu T,Biondi-Zoccai G,de Farias JM

更新日期：2019-02-02 00:00:00

abstract：PURPOSE OF REVIEW:High lipoprotein(a) levels are observationally and causally, from human genetics, associated with increased risk of cardiovascular disease including myocardial infarction and aortic valve stenosis. The European Atherosclerosis Society recommends screening for elevated lipoprotein(a) levels in high-ris...

journal_title：Current atherosclerosis reports

authors： Langsted A,Nordestgaard BG

更新日期：2019-05-20 00:00:00

abstract：:Several studies confirm cognitive impairment and dementia to be increased after stroke in the elderly. Although not necessarily involving memory deficits, the frequency of cognitive impairments may occur in up to 30% of stroke survivors at 3 months. This impairment may be confounded by preexisting cognitive decline or...

journal_title：Current atherosclerosis reports

authors： Kalaria RN,Ballard C

更新日期：2001-07-01 00:00:00

abstract：PURPOSE OF REVIEW:We will review the available data on the epidemiology, pathophysiology, diagnosis, and management of microvascular coronary dysfunction (MCD). RECENT FINDINGS:The study of MCD was pioneered by the Women's Ischemia Syndrome Evaluation (WISE) cohort. New techniques in the diagnosis of this condition, u...

journal_title：Current atherosclerosis reports

authors： Naderi S

更新日期：2018-01-30 00:00:00

abstract：:The original version of this article contains errors in Table 3. "At least 1 project/publication in the year" and "> 1 publication per year" have been switched under the titles of "Clinical Track" and "Physician-Scientist track". ...

journal_title：Current atherosclerosis reports

authors： Saeed A,Dabhadkar K,Virani SS,Jones PH,Ballantyne CM,Nambi V

更新日期：2018-06-19 00:00:00

abstract：:Cardiovascular disease and its clinical sequelae remain the leading causes of morbidity and mortality in many regions of the world. Dyslipidemia is a critical risk factor to intercept in both the primary and secondary prevention of acute cardiovascular events. The prospective, placebo-controlled clinical trials conduc...

journal_title：Current atherosclerosis reports

authors： Toth PP

更新日期：2004-09-01 00:00:00

abstract：:Atherothrombosis remains a major cause of morbidity and mortality in the western world. The underlying processes associated with clinical expression of atherothrombosis include oxidative stress and proteolysis in relation to neovascularisation and intraplaque hemorrhages, leading to immuno-inflammatory response, cell ...

journal_title：Current atherosclerosis reports

authors： Martinez-Pinna R,Barbas C,Blanco-Colio LM,Tunon J,Ramos-Mozo P,Lopez JA,Meilhac O,Michel JB,Egido J,Martin-Ventura JL

更新日期：2010-05-01 00:00:00

abstract：:Various lifestyle factors have been associated with increasing the risk of stroke. These include lack of exercise, alcohol, diet, obesity, smoking, drug use, and stress. Guidelines endorsed by the Centers for Disease Control and Prevention and the National Institutes of Health recommend that Americans should exercise ...

journal_title：Current atherosclerosis reports

authors： Boden-Albala B,Sacco RL

更新日期：2000-03-01 00:00:00

abstract：:Patients with ischemic stroke of unclear etiology are often screened for hypercoagulable syndromes or thrombophilias. These have been recognized to cause venous thrombosis, and include hereditary deficiencies of coagulation factors, genetic mutations, or acquired disorders. However, the majority of coagulation disorde...

journal_title：Current atherosclerosis reports

authors： Bushnell C,Goldstein LB

更新日期：2003-07-01 00:00:00

abstract：:Diabetes and its micro- and macrovascular complications represent a worldwide epidemic that will place an enormous financial burden on poorer countries in the years to come. In patients with diabetes and hypertension, the main determinant of the cardiovascular and renal benefits of antihypertensive drugs is the blood ...

journal_title：Current atherosclerosis reports

authors： Reboldi G,Gentile G,Angeli F,Verdecchia P

更新日期：2011-04-01 00:00:00

abstract：:The cytochrome P450 (CYP) is a group of enzymes that oxidatively modify drugs to a more water-soluble form for renal excretion. Nearly 50% of all clinically used medications and endogenous steroids are metabolized by the CYP enzyme 3A4, which explains why many of the important potential drug interactions involved this...

journal_title：Current atherosclerosis reports

authors： Davidson MH

更新日期：2000-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Coronary artery no-reflow phenomenon is an incidental outcome of percutaneous coronary intervention in patients presenting with acute myocardial infarction. Despite advances in pharmacologic and non-pharmacologic therapies, coronary no-reflow phenomenon occurs more commonly than desired. It often resu...

journal_title：Current atherosclerosis reports

authors： Karimianpour A,Maran A

更新日期：2018-07-05 00:00:00

abstract：:Effective prevention of the current annual $400 billion losses from atherosclerosis and cardiovascular disease (CVD) will require preventing primary causes rather than just decreasing signs and symptoms (risk factors) produced by those causes. All CVD risk factors predict a likelihood of CVD, but not all are causes of...

journal_title：Current atherosclerosis reports

authors： Lands B

更新日期：2009-07-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome and a risk factor for both cardiovascular and hepatic related morbidity and mortality. The increasing prevalence of this disease requires novel therapeutic approaches to prevent disease progression. Farnesoid X receptors a...

journal_title：Current atherosclerosis reports

authors： Carr RM,Reid AE

更新日期：2015-04-01 00:00:00

abstract：:The Third Report of the National Cholesterol Education Program's Adult Treatment Panel (ATP III) has an extensive section on nonpharmacologic therapy for those with abnormal blood lipids. ATP III focused on the high-saturated fat atherogenic diet, obesity, and sedentary lifestyle and recommended a program of therapeut...

journal_title：Current atherosclerosis reports

authors： Stone NJ,Van Horn L

更新日期：2002-11-01 00:00:00