Preparation of lactose-modified cellulose films by a nonaqueous enzymatic reaction and their biofunctional characteristics as a scaffold for cell culture.

abstract：:Single-molecule measurements of the interaction of leukocyte function-associated antigen-1 (LFA-1), expressed on Jurkat T cells, with intercellular adhesion molecules-1 and -2 (ICAM-1 and ICAM-2) were conducted using atomic force microscopy (AFM). The force spectra (i.e., unbinding force versus loading rate) of both t...

journal_title：Biomacromolecules

authors： Wojcikiewicz EP,Abdulreda MH,Zhang X,Moy VT

更新日期：2006-11-01 00:00:00

abstract：:The thermal conductive properties, including the thermal diffusivity and resultant thermal conductivity, of nonwoven nanocellulose sheets were investigated by separately measuring the thermal diffusivity of the sheets in the in-plane and thickness directions with a periodic heating method. The cross-sectional area (or...

journal_title：Biomacromolecules

authors： Uetani K,Okada T,Oyama HT

更新日期：2015-07-13 00:00:00

abstract：:The new combinations of monomers presented in this work were evaluated in order to create an elastic material for potential application in soft tissue engineering. Thermoplastic elastomers (TPE) of trimethylene carbonate (TMC) with L-lactide (LLA) and 1,5-dioxepan-2-one (DXO) have been synthesized using a cyclic five-...

journal_title：Biomacromolecules

authors： Andronova N,Albertsson AC

更新日期：2006-05-01 00:00:00

abstract：:Prevention of biofouling and microbial contamination of implanted biomedical devices is essential to maintain their functionality and biocompatibility. For this purpose, polypept(o)ide block copolymers have been developed, in which a protein-resistant polysarcosine (pSar) block is combined with a dopamine-modified pol...

journal_title：Biomacromolecules

authors： Yoo J,Birke A,Kim J,Jang Y,Song SY,Ryu S,Kim BS,Kim BG,Barz M,Char K

更新日期：2018-05-14 00:00:00

abstract：:Cationic derivatives of cellulose and other polysaccharides are attractive targets for biomedical applications due to their propensity for electrostatically binding with anionic biomolecules, such as nucleic acids and certain proteins. To date, however, relatively few practical synthetic methods have been described fo...

journal_title：Biomacromolecules

authors： Liu S,Liu J,Esker AR,Edgar KJ

更新日期：2016-02-08 00:00:00

abstract：:Given the significance of hydrogels as cell-instructive materials, it is important to understand how differences in their chemical and physical properties are able to direct cell fate. For example, it remains unclear how different hydrogel cross-linking chemistries and gelation mechanisms influence cell behavior. Here...

journal_title：Biomacromolecules

authors： Loebel C,Szczesny SE,Cosgrove BD,Alini M,Zenobi-Wong M,Mauck RL,Eglin D

更新日期：2017-03-13 00:00:00

abstract：:Cellular uptake and intracellular targeting to specific organelles are key events in the cellular processing of nanomaterials. Herein, we perform a detailed structure-property relationship study on carboxylic acid-side-chain-bearing polyacrylates to provide design criteria for the manipulation of their cellular intera...

journal_title：Biomacromolecules

authors： Mahmoud AM,Morrow JP,Pizzi D,Azizah AM,Davis TP,Tabor RF,Kempe K

更新日期：2020-08-10 00:00:00

abstract：:On the basis of their versatile structure and chemistry as well as tunable mechanical properties, polymer brushes are well-suited as supports for enzyme immobilization. However, a robust surface design is hindered by an inadequate understanding of the impact on activity from the coupling motif and enzyme distribution ...

journal_title：Biomacromolecules

authors： Lane SM,Kuang Z,Yom J,Arifuzzaman S,Genzer J,Farmer B,Naik R,Vaia RA

更新日期：2011-05-09 00:00:00

abstract：:The elegant elasticity and toughness of muscles that are controlled by myofilament sliding, highly elastic springlike properties of titin, and Ca2+-induced conformational change of the troponin complex have been a source of inspiration to develop advanced materials for simulating elastic muscle motion. Herein, a highl...

journal_title：Biomacromolecules

authors： Zhao L,Zhang X,Luo Q,Hou C,Xu J,Liu J

更新日期：2020-10-12 00:00:00

abstract：:Imbalanced homeostasis and oligomerization of the amyloid-β (Aβ) peptide in the brain are hallmarks of Alzheimer's disease (AD). Microglia and macrophages play a critical role in the etiology of AD either by clearing Aβ from the brain or inducing inflammation. Recent evidence suggests that clearance of Aβ by microglia...

journal_title：Biomacromolecules

authors： Richman M,Perelman A,Gertler A,Rahimipour S

更新日期：2013-01-14 00:00:00

abstract：:Neutron reflectometry was used to investigate the time-dependent beta-casein adsorption at the silica-aqueous solution interface. The transient and steady-state structural characteristics of the adsorbed layer were determined from reflectivity curves, fitted to three-layer and two-layer models. The results show that t...

journal_title：Biomacromolecules

authors： Tiberg F,Nylander T,Su TJ,Lu JR,Thomas RK

更新日期：2001-10-01 00:00:00

abstract：:Antifreeze glycoproteins (AFGPs) are a subclass of biological antifreezes found in deep sea Teleost fish. These compounds have the ability to depress the freezing point of the organism such that it can survive the subzero temperatures encountered in its environment. This physical property is very attractive for the cr...

journal_title：Biomacromolecules

authors： Liu S,Wang W,Moos Ev,Jackman J,Mealing G,Monette R,Ben RN

更新日期：2007-05-01 00:00:00

abstract：:The formation of calcite prism architecture in the prismatic layer of the mollusk shell involves the participation of a number of different proteins. One protein family, Asprich, has been identified as a participant in amorphous calcium carbonate stabilization and calcite architecture in the prismatic layer of the mol...

journal_title：Biomacromolecules

authors： Ndao M,Keene E,Amos FF,Rewari G,Ponce CB,Estroff L,Evans JS

更新日期：2010-10-11 00:00:00

abstract：:Visible light-induced hydrogelation is attractive for various biomedical applications. In this study, hydrogels of alginate with phenolic hydroxyl groups (Alg-Ph) were obtained by irradiating a solution containing the polymer, ruthenium II trisbipyridyl chloride ([Ru(bpy)3]2+) and sodium persulfate (SPS), with visible...

journal_title：Biomacromolecules

authors： Sakai S,Kamei H,Mori T,Hotta T,Ohi H,Nakahata M,Taya M

更新日期：2018-02-12 00:00:00

abstract：:As a first step toward utilizing self-assembling peptide scaffolds to create tunable matrices for drug delivery, peptide RADAFI and RADAFII, containing the same amino acid composition but different positions of one phenylalanine residue, scaffolds were prepared for controlled release of chiral enantiomers. The release...

journal_title：Biomacromolecules

authors： Zhao Y,Tanaka M,Kinoshita T,Higuchi M,Tan T

更新日期：2009-12-14 00:00:00

abstract：:Degradation of fibrillar collagen is critical for tissue maintenance. Yet, understanding collagen catabolism has been challenging partly due to a lack of atomistic picture for its load-dependent conformational dynamics, as both mechanical load and local unfolding of collagen affect its cleavage by matrix metalloprotei...

journal_title：Biomacromolecules

authors： Teng X,Hwang W

更新日期：2014-08-11 00:00:00

abstract：:A new mathematical model is presented for the analysis of the substituent distribution in the polymer chain of polysaccharide derivatives. For the first time, the influence of substitution on the reactivity of neighbored monomer units is taken into account. The model was applied to various cellulose and amylose ethers...

journal_title：Biomacromolecules

authors： Mischnick P,Hennig C

更新日期：2001-04-01 00:00:00

abstract：:Medical glue represents a suitable tool to stop wound bleeding, seal wounds, bond tissues, or implant materials. However, the development of a medical glue for durable underwater bonding remains a challenge. Herein, we developed a hydrophobic hyperbranched polymer-based medical glue with water-resistant bonding abilit...

journal_title：Biomacromolecules

authors： Zhang Y,Li X,Zhu Q,Wei W,Liu X

更新日期：2020-12-14 00:00:00

abstract：:Synthesis of novel zwitterionic block copolypeptides, poly(N-isopropylacrylamide)-block-poly(L-glutamic acid-co-L-lysine) [PNiPAM(n)(PLG(x)-co-PLLys(y))m , where n is the number-average degree of polymerization (DP(n)) of PNiPAM block, x and y are the mole fraction of glutamic acid and lysine residues, respectively, a...

journal_title：Biomacromolecules

authors： Li J,Wang T,Wu D,Zhang X,Yan J,Du S,Guo Y,Wang J,Zhang A

更新日期：2008-10-01 00:00:00

abstract：:A strategy to manipulate the disulfide bond breaking triggered unfolding, and subsequently assembly of human serum albumin (HSA) in a lipophilic drug-dependent manner is present. In this study, the hydrophobic region, a molecular switch of the HSA, was regulated to form HSA-paclitaxel (HSA-PTX) nanoparticles by a faci...

journal_title：Biomacromolecules

authors： Gong G,Xu Y,Zhou Y,Meng Z,Ren G,Zhao Y,Zhang X,Wu J,Hu Y

更新日期：2012-01-09 00:00:00

abstract：:Alginate-based amphiphilic graft copolymers were synthesized by single electron transfer living radical polymerization (SET-LRP), forming stable micelles during polymerization induced self-assembly (PISA). First, alginate macroinitiator was prepared by partial depolymerization of native alginate, solubility modificati...

journal_title：Biomacromolecules

authors： Kapishon V,Whitney RA,Champagne P,Cunningham MF,Neufeld RJ

更新日期：2015-07-13 00:00:00

abstract：:Collagen is a versatile structural molecule in nature and is used as a building block in many highly organized tissues, such as bone, skin, and cornea. The functionality and performance of these tissues are controlled by their hierarchical organization ranging from the molecular up to macroscopic length scales. In the...

journal_title：Biomacromolecules

authors： Masic A,Bertinetti L,Schuetz R,Galvis L,Timofeeva N,Dunlop JW,Seto J,Hartmann MA,Fratzl P

更新日期：2011-11-14 00:00:00

abstract：:An increase in hyaluronan (HA) synthesis, cellular uptake, and metabolism occurs during the remodeling of tissue microenvironments following injury and during disease processes such as cancer. We hypothesized that multimodality HA-based probes selectively target and detectably accumulate at sites of high HA metabolism...

journal_title：Biomacromolecules

authors： Veiseh M,Breadner D,Ma J,Akentieva N,Savani RC,Harrison R,Mikilus D,Collis L,Gustafson S,Lee TY,Koropatnick J,Luyt LG,Bissell MJ,Turley EA

更新日期：2012-01-09 00:00:00

abstract：:Polymerized high internal phase emulsions (polyHIPEs) have been utilized in the creation of injectable scaffolds that cure in situ to fill irregular bone defects and potentially improve tissue healing. Previously, thermally initiated scaffolds required hours to cure, which diminished the potential for clinical transla...

journal_title：Biomacromolecules

authors： Moglia RS,Whitely M,Dhavalikar P,Robinson J,Pearce H,Brooks M,Stuebben M,Cordner N,Cosgriff-Hernandez E

更新日期：2014-08-11 00:00:00

abstract：:A multiple targeted drug carrying bilayer membrane for preventing an abdominal adhesion is prepared by electrospinning. Two bioactive drugs were successfully incorporated into this bilayer membrane and can be independently released from nanofibrous scaffolds without losing structural integrity and functionality of the...

journal_title：Biomacromolecules

authors： Wang H,Li M,Hu J,Wang C,Xu S,Han CC

更新日期：2013-04-08 00:00:00

abstract：:Although research on nanopaper structures from cellulose nanofibrils (CNFs) is well established, the mechanical behavior is not well understood, especially not when CNF is combined with hard nanoparticles. Cationic CNF (Q-CNF) was prepared and successfully decorated by anionic nanodiamond (ND) nanoparticles in hydroco...

journal_title：Biomacromolecules

authors： Morimune-Moriya S,Salajkova M,Zhou Q,Nishino T,Berglund LA

更新日期：2018-07-09 00:00:00

abstract：:One of the major drawbacks found in most bone tissue engineering approaches developed so far consists in the lack of strategies to promote vascularisation. Some studies have addressed different issues that may enhance vascularisation in tissue engineered constructs, most of them involving the use of growth factors (GF...

journal_title：Biomacromolecules

authors： Santo VE,Frias AM,Carida M,Cancedda R,Gomes ME,Mano JF,Reis RL

更新日期：2009-06-08 00:00:00

abstract：:Bionanocomposite materials, combining the properties of biopolymers and nanostructured materials, are attracting interest of the wider scientific community due to their potential application in design of implants, drug delivery systems, and tissue design platforms. Herein, we report on the use of maleimide-coated silv...

journal_title：Biomacromolecules

authors： García-Astrain C,Chen C,Burón M,Palomares T,Eceiza A,Fruk L,Corcuera MÁ,Gabilondo N

更新日期：2015-04-13 00:00:00

abstract：:Well-defined linear poly(acryloyl glucosamine) (PAGA) exhibiting molar masses ranging from 3 to 120 K and low polydispersities have been prepared via reversible addition-fragmentation chain transfer polymerization (RAFT) in aqueous solution without recourse to protecting group chemistry. The livingness of the process ...

journal_title：Biomacromolecules

authors： Bernard J,Hao X,Davis TP,Barner-Kowollik C,Stenzel MH

更新日期：2006-01-01 00:00:00

abstract：:We study the fibrillation pathway of ovalbumin protein and report the simultaneous formation of several types of fibrils, with clear structural and physical differences. We compare the fibrillation mechanisms at low pH with and without salt, and follow the kinetics of fibrils growth by atomic force microscopy (AFM), s...

journal_title：Biomacromolecules

authors： Lara C,Gourdin-Bertin S,Adamcik J,Bolisetty S,Mezzenga R

更新日期：2012-12-10 00:00:00