Abstract:
:The recent discovery of IL-17-producing CD4(+) Th subset significantly revised the Th1/Th2 dichotomy model proposed by Mosmann and Coffman almost two decades ago. Th17 cells are involved in the pathogenesis of many human autoimmune diseases. Th17 cells, their developmental pathways and their effector functions, therefore, provide novel therapeutic targets.
journal_name
Eur J Immunoljournal_title
European journal of immunologyauthors
Ouyang W,Filvaroff E,Hu Y,Grogan Jdoi
10.1002/eji.200839105subject
Has Abstractpub_date
2009-03-01 00:00:00pages
670-5issue
3eissn
0014-2980issn
1521-4141journal_volume
39pub_type
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journal_title:European journal of immunology
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journal_title:European journal of immunology
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journal_title:European journal of immunology
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