Abstract:
PURPOSE:Ultraviolet light from sunlight and other sources is the major environmental risk factor for melanoma of the skin. Humans also derive most of their vitamin D from exposure to sunlight. This article reviews current evidence that vitamin D might play a preventive role in the development of melanoma or affect tumor aggressiveness or melanoma patient outcomes. METHODS:Literature review. RESULTS:The vitamin D receptor has been identified in normal melanocytes as well as melanoma cell lines and primary tissue. A few studies have demonstrated relationships of functional polymorphisms in the vitamin D receptor with melanoma risk or tumor aggressiveness. Identifying an independent influence of vitamin D on melanoma risk is hampered by overwhelming confounding by the carcinogenic influence of ultraviolet radiation on skin melanocytes. Nonetheless an inverse association was suggested in a few studies with greater consumption of dairy foods or other dietary sources. Several lines of evidence are consistent with a potential influence for vitamin D on site-specific aggressiveness of skin melanomas, therapeutic response or patient survival. CONCLUSION:Additional research is needed to determine whether vitamin D may have a preventive role in melanoma incidence or a salutary influence on melanoma patient outcome.
journal_name
Ann Epidemioljournal_title
Annals of epidemiologyauthors
Egan KMdoi
10.1016/j.annepidem.2009.01.005subject
Has Abstractpub_date
2009-07-01 00:00:00pages
455-61issue
7eissn
1047-2797issn
1873-2585pii
S1047-2797(09)00016-7journal_volume
19pub_type
杂志文章,评审abstract::The Expanded Programme on Immunization (EPI) of the World Health Organization developed a cluster survey design for the rapid assessment of children's vaccination coverage in developing countries. Because of its simplicity and familiarity, the EPI methodology has been used for additional purposes, including the detect...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/1047-2797(94)90086-8
更新日期:1994-07-01 00:00:00
abstract::The association of physical activity to plasma lipid and lipoprotein levels was examined cross-sectionally in 634 elderly, postmenopausal women whose mean age was 70.7 years. Leisure-time physical activity in kilocalories per week was assessed by the Paffenbarger Questionnaire, a composite index of sports/recreation, ...
journal_title:Annals of epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1016/1047-2797(93)90061-8
更新日期:1993-07-01 00:00:00
abstract:PURPOSE:The purpose of this study was to describe time trends in response rates in case-control studies of cancer and identify study design factors that influence response rate. METHODS:We reviewed 370 case-control studies of cancer published in 12 journals during indicator years in each of the last four decades. We e...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2018.04.001
更新日期:2018-06-01 00:00:00
abstract:PURPOSE:Diabetes increases the risk of ischemic heart disease (IHD). Stringent control of diabetes does not reliably reduce cardiovascular events. Some global regions, such as East Asia, have low mortality rates from IHD and high rates of diabetes. We hypothesized that some aspects of liver function might underlie this...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2012.08.003
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:Several mathematical models simulate a HIV/AIDS epidemic by using the assumption that heterosexual transmission is the major or sole transmission mode. The validity of these models has been unclear. To understand the validity of these models, empirical estimates for relevant model parameters are needed that can...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2006.10.011
更新日期:2007-03-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate prospectively smoking dependence as a predictor of repeated use of prescribed opioids in non-cancer patients. METHODS:We conducted a prospective population-based study cohort of 12,848 men and 15,894 women 30-75 years of age in health surveys in Norway during 2000-2002 wit...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2010.03.010
更新日期:2010-12-01 00:00:00
abstract:PURPOSE:A literature review was performed of the three principal subpopulations most commonly associated with human T-cell lymphotropic virus type II (HTLV-II) with the view of identifying the prevalence and transmission routes of HTLV-II. These included blood donors (BDs), intravenous drug users (IVDUs), and Amerindia...
journal_title:Annals of epidemiology
pub_type: 杂志文章,评审
doi:10.1016/s1047-2797(01)00231-9
更新日期:2002-01-01 00:00:00
abstract:PURPOSE:To determine whether homocyst(e)ine (H(e)) is related to hemostatic factors in a population-based sample without evidence of cardiovascular disease. METHODS:A subsample of 660 participants--67 African-American women, 53 African-American men, 201 white women, and 339 white men--was selected from the Atheroscler...
journal_title:Annals of epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1016/s1047-2797(01)00311-8
更新日期:2002-05-01 00:00:00
abstract::Some of the readjustment problems of Vietnam veterans have been attributed to posttraumatic stress disorder (PTSD). This case-control study compared demographic and military characteristics of 374 Vietnam veterans who had PTSD with 373 healthy Vietnam veterans. Veterans were chosen from the Agent Orange Registry, a De...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/1047-2797(91)90022-5
更新日期:1991-11-01 00:00:00
abstract:PURPOSE:Population-based cancer incidence rates of the corpus uteri, cervix uteri, and ovaries are underestimated if they fail to remove women not at risk for developing the cancers from the denominator in the race calculation. This study compares incidence rates among selected racial groups for these cancers before an...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2006.06.001
更新日期:2006-12-01 00:00:00
abstract:PURPOSE:Continuous monitoring of health determinants in populations is necessary to predict future disease burdens. The objective of this study was to assess the prevalences of major risk factors for lifestyle diseases for 8 years (1993 to 2000) in representative samples of the general population. METHODS:Independent ...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/s1047-2797(03)00055-3
更新日期:2003-08-01 00:00:00
abstract:PURPOSE:Physical activity helps maintain mobility, physical functioning, bone mineral density (BMD), muscle strength, balance and, therefore, may help prevent falls and fractures among the elderly. Meanwhile, it is theoretically possible that physical activity increases risk of fractures as it may increase risk of fall...
journal_title:Annals of epidemiology
pub_type: 杂志文章,meta分析
doi:10.1016/j.annepidem.2008.08.007
更新日期:2008-11-01 00:00:00
abstract::The objective of this study was to examine whether fasting serum insulin is a predictor of coronary heart disease in high-risk US men, and whether any such predictive role explains the enhanced cardiovascular risk seen in subjects with the apolipoprotein (Apo) E 3/2 phenotype. This was a nested case-control study of p...
journal_title:Annals of epidemiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/1047-2797(94)90041-8
更新日期:1994-01-01 00:00:00
abstract:PURPOSE:C-reactive protein (CRP), androgens, and menopausal loss of endogenous estrogens are associated with cardiovascular disease (CVD). We hypothesized that high androgens, low estradiol, and low sex hormone-binding globulin (SHBG) would be associated with high CRP in postmenopausal women. METHODS:CRP, SHBG, estrad...
journal_title:Annals of epidemiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.annepidem.2005.07.055
更新日期:2006-02-01 00:00:00
abstract:PURPOSE:The purpose of this study was to estimate the heart rate variability (HRV)-related lifetime cardiovascular disease (CVD) risk. METHODS:We followed 9744 participants without baseline CVD and used a life-table approach to estimate lifetime CVD risk (coronary heart disease, heart failure, and stroke) from 45 thro...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2017.08.024
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:The health of infants that are HIV-exposed and -uninfected (HEU) is a major public health concern as HIV becomes a chronic condition. We investigate the interrelationship between maternal viral suppression, maternal weight status, breastfeeding, and infants that are HEU. METHODS:The Kabeho study followed 502 H...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2020.08.008
更新日期:2021-01-01 00:00:00
abstract::The association between premature menopause and low back pain was examined among 5325 women surveyed in the second National Health and Nutrition Examination survey. Nearly 49% of the women were postmenopausal. In a multiple logistic regression model that included age, postmenopausal women were approximately twice as l...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/1047-2797(94)90077-9
更新日期:1994-09-01 00:00:00
abstract:PURPOSE:In prospective cohort studies, incidence is typically estimated by the ratio of the observed number of events to person-time at risk. This crude estimator is consistent for the true population incidence rate (IR) under mild assumptions. Here we consider a different setting where only cross-sectional data are av...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2020.06.005
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:We examined the prevalence of high levels of depressive symptoms and their association with sociodemographic and health characteristics in an urban Korean population following the financial crisis in late 1997. METHODS:Using data from a cross-sectional survey conducted in Ansan-city, Korea, from June 1999 to J...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2004.05.004
更新日期:2005-02-01 00:00:00
abstract:PURPOSE:To examine the clustering and patterns of obesity-related behaviors in children and their mothers and the concordance between mother and child pairs. METHODS:Primary school-aged children and their mothers in Victoria, Australia, participated (data from 549 mothers, 352 children, and 304 mother/child pairs). Ex...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2010.11.001
更新日期:2011-02-01 00:00:00
abstract:PURPOSE:To investigate the possible association between ibuprofen use and dermatologic superinfections among children with recent varicella infection. METHODS:A retrospective cohort study of children in Harvard Pilgrim Health Care, a health maintenance organization in New England, was conducted. Outcomes and exposures...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/s1047-2797(97)00040-9
更新日期:1997-10-01 00:00:00
abstract::PURPOSE: Although prison inmates are reported to exhibit substantially elevated rates of HIV infection, little is known about HIV treatment patterns, particularly pharmacotherapy, in correctional institutions. The purpose of the present study, therefore, was to describe antiretroviral prescribing patterns in one of th...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/s1047-2797(00)00128-9
更新日期:2000-10-01 00:00:00
abstract:PURPOSE:To investigate the association of nativity status, country of origin, and race with all-cause mortality in Hispanic adults relative to non-Hispanic adults in the United States, we used 565,352 records of participants 25 years and older from years 1990 to 2000 of the National Health Interview Survey linked to th...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2008.12.003
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:A common epidemiologic objective is to evaluate the contribution of residential context to individual-level disparities by race or socioeconomic position. PURPOSE:We reviewed analytic strategies to account for the total (observed and unobserved factors) contribution of environmental context to health inequa...
journal_title:Annals of epidemiology
pub_type: 杂志文章,评审
doi:10.1016/j.annepidem.2012.06.105
更新日期:2012-10-01 00:00:00
abstract::To evaluate previously reported associations with cigarette smoking, the incidence of leukemia and multiple myeloma was determined with follow-up of up to 24 years of 57,224 never-smokers, 20,928 former smokers, and 64,839 current cigarette smokers who received multiphasic health checkups. Cigarette smoking was associ...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/1047-2797(93)90071-b
更新日期:1993-07-01 00:00:00
abstract:PURPOSE:To assess intake of several vitamins in preparation for a large cohort study investigating the effect of diet on risk of colon and prostate cancer. METHODS:The dietary intake of several vitamins were assessed using eight different 24-hour recalls and a 200-item food frequency questionnaire (FFQ) from each subj...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/s1047-2797(01)00224-1
更新日期:2001-08-01 00:00:00
abstract:PURPOSE:To determine whether bladder cancer is associated with exposure to perfluorooctane sulfonate (PFOS) in an occupational cohort. METHODS:Incidence of bladder cancer was ascertained by postal questionnaire to all living current and former employees of the facility (N = 1895) and death certificates for deceased wo...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2007.01.036
更新日期:2007-06-01 00:00:00
abstract:PURPOSE:As Western populations live longer, peripheral vascular disease will become a greater individual and public health problem. Therefore, the long-term natural history of intermittent claudication (IC) needs further delineation. The study objective was to describe the 21-year mortality and relative risk for cause-...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/s1047-2797(96)00148-2
更新日期:1997-04-01 00:00:00
abstract:PURPOSE:To examine geographic variation in the incidence of ischemic stroke (IS) and acute myocardial infarction (AMI) in Finland during 1991-2003. METHODS:Data included all cases of first IS (n = 115,383) and AMI (n = 205,213) in persons aged 35-84 years. We used full Bayesian spatial shared component disease models ...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2007.10.008
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:Simpson's paradox is a type of severe confounding wherein a confounding variable changes the direction of an association. METHODS:This article demonstrates Simpson's paradox with three cohorts of naproxen users (new users, chronic users, and combined users) who were compared on the age/sex distribution of furt...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/s1047-2797(97)00084-7
更新日期:1997-10-01 00:00:00