Abstract:
BACKGROUND:The meningitides are rare but well-identified complications in patients with systemic lupus erythematosus (SLE). AIMS:To determine the clinical characteristics, risk factors, prevalence and outcomes of the meningitides (septic and aseptic) in patients with SLE. PATIENTS AND METHODS:From January 1988 to December 2006, we identified patients with SLE and septic or aseptic meningitis. RESULTS:We identified 25 episodes of meningitis in 23 patients with SLE, from a total of 1,411 SLE patients (1.63%); in 15 out of 25 episodes, a microorganism was identified. Mycobacterium tuberculosis, Listeria monocytogenes and Criptococcus neoformans represented the main microorganisms. In 10 episodes, aseptic meningitis was diagnosed. Lymphopenia, steroid use, chronic damage and systemic activity of SLE were frequent in both kinds of meningitis. Although the clinical presentation did not differ significantly, patients with septic meningitis had more residual neurological deficits (p = 0.04). CONCLUSIONS:Meningitis was observed in about 1.6% of the patients with SLE; in 40% of the cases, no microorganism could be isolated. A residual neurological deficit was more common in patients with septic meningitis.
journal_name
Eur Neuroljournal_title
European neurologyauthors
Baizabal-Carvallo JF,Delgadillo-Márquez G,Estañol B,García-Ramos Gdoi
10.1159/000186504subject
Has Abstractpub_date
2009-01-01 00:00:00pages
143-8issue
3eissn
0014-3022issn
1421-9913pii
000186504journal_volume
61pub_type
杂志文章abstract::Nerve conduction of single impulses and the ability to transmit frequent trains of stimuli were studied in sensory median and in sural nerves of controls and patients with diabetes mellitus. Decrease of relative amplitudes and increase of relative latencies were more marked in the diabetics as compared with normal con...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115123
更新日期:1980-01-01 00:00:00
abstract::Hypertrophic changes in the inferior olivary nuclei have been occasionally described in patients with progressive supranuclear palsy (PSP). To elucidate the incidence of olivary hypertrophy, we investigated morphologically the olives and their associated pathways in 20 autopsied cases: 11 cases of PSP, 3 cases of Mach...
journal_title:European neurology
pub_type: 临床试验,杂志文章
doi:10.1159/000007915
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Thalamic lesion due to deep cerebral venous thrombosis (DCVT) is an uncommon cause of stroke. Until now, only a few case reports have been published. The aim of the study is to report the clinical and radiological findings of thalamic lesion with DCVT. METHODS:We reviewed our computerized stroke database of...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000439167
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Several treatments are available to treat the immune-mediated chronic inflammatory demyelinating polyneuropathy (CIDP). Among these treatments, intravenous immunoglobulins, corticosteroids and plasma exchanges are validated and widely used. A few immunosuppressive drugs have been tried, but they had little e...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000381767
更新日期:2015-01-01 00:00:00
abstract::Patients suffering from migraine, tension-type headache (TTH), or combined headache (CH) are at risk of developing drug-induced headache (DIH) due to regular use of analgesics, ergot alkaloids, and triptans. The aim of our study was to determine (1) the clinical features of DIH, (2) the outcome of withdrawal therapy u...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000052134
更新日期:2001-01-01 00:00:00
abstract::We present a long-term follow-up examination concerning patients with isolated extra-ocular muscle involvement in thyroid-related orbitopathy. Within the previous 13 years we observed 7 patients with endocrine orbitopathy and marked myopathy of the extra-ocular muscles. Five of these patients had no detectable proptos...
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更新日期:2008-01-01 00:00:00
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更新日期:2020-01-01 00:00:00
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journal_title:European neurology
pub_type: 杂志文章,多中心研究
doi:10.1159/000447059
更新日期:2016-01-01 00:00:00
abstract::The management of early Parkinson's disease (PD) involves the treatment of motor symptoms and, increasingly, non-motor symptoms. Given the fast pace of clinical research in PD, clinicians are faced with the challenge of integrating the latest findings into the ongoing care of individual PD patients. Part 1 of this 2-p...
journal_title:European neurology
pub_type: 杂志文章,评审
doi:10.1159/000197103
更新日期:2009-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2012-01-01 00:00:00
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journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000008187
更新日期:2000-01-01 00:00:00
abstract::Five patients with monomelic spinal muscular atrophy are described. Clinical features included insidious onset of wasting and weakness of one limb, lack of involvement of the cranial nerves, brain stem, pyramidal tracts and sensory system, and a stable condition over a period of 4-20 years. Clinical findings, electrom...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116249
更新日期:1988-01-01 00:00:00
abstract::This paper records a patient of Osler's, who showed many features compatible with the Churg-Strauss syndrome of allergic granulomatous angiitis to be described 50 years later. ...
journal_title:European neurology
pub_type: 历史文章,杂志文章
doi:10.1159/000098474
更新日期:2007-01-01 00:00:00
abstract::The role of genetics in Parkinson's disease (PD), previously controversial, is now documented by several studies. A major breakthrough has been the discovery of two single-gene defects in familial PD. A single base pair change at position 209 from G to A (G209A) in the fourth exon of the alpha-synuclein gene has been ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000008203
更新日期:2000-01-01 00:00:00
abstract::Report on a series of patients suffering from cerebrovascular insufficiency caused by stenosis and/or occlusion of one or several major cerebral vessels. The patients were divided in two groups, one being medically treated with anticoagulants, the other operated on either a carotid artery thrombosis by thromboendarter...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000115140
更新日期:1980-01-01 00:00:00
abstract::To quantitate embolic risk we studied a retrospective series of 61 patients with strictly defined bacterial endocarditis. Eighteen patients had neurological complications attributable to cerebral embolism. Seventeen embolic episodes occurred prior to antibiotic treatment and 8 episodes after its commencement. The rate...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000117317
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to elucidate the influence of insular infarction on blood pressure (BP) variability and outcomes according to the region of the insular cortex affected. METHODS:A total of 90 patients diagnosed with acute unilateral ischemic stroke were registered. The BP variability was calculated...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000486306
更新日期:2018-01-01 00:00:00
abstract::Sixteen children with definite multiple sclerosis (MS; aged 6-17 years, mean 11.4 +/- 2.7; 8 boys, 8 girls) were reviewed. Cerebellar symptoms and signs were frequent at initial presentation. Among laboratory studies, the cerebrospinal fluid (CSF) IgG index or oligoclonal bands were informative in 75%, evoked potentia...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000117213
更新日期:1996-01-01 00:00:00
abstract::Kearns-Sayre syndrome has been associated with large heteroplasmic mitochondrial DNA deletions and morphological alterations at the cytological level. We have measured the activities of different respiratory chain complexes in 3 patients presenting mitochondrial DNA deletions and found no close correlation between gen...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116656
更新日期:1991-01-01 00:00:00
abstract::Fatigue is one of the most frequent and most disabling symptoms in multiple sclerosis (MS). We investigated the possible association of the MS-related fatigue syndrome with the available disease-modifying therapies and the main disease characteristics in a cross-sectional study on 320 consecutive patients. The prevale...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000111876
更新日期:2008-01-01 00:00:00
abstract::The pathogenesis of primary degenerative dementia is still unknown and current therapeutic approaches can aim only at ameliorating some of the symptoms associated with this brain disease. At present, most approaches, attempt to correct a cholinergic deficit. Although the therapeutic benefits obtained so far with curre...
journal_title:European neurology
pub_type: 杂志文章,评审
doi:10.1159/000116479
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Assessing collateral status is important in acute ischemic stroke. The purpose of this study was to compare multiphasic perfusion computed tomography (MPCT) with digital subtraction angiography (DSA) in predicting leptomeningeal collateral flow in acute middle cerebral artery (MCA) infarction. METHODS:Conse...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000334867
更新日期:2012-01-01 00:00:00
abstract::The hypothesis that mitochondrial genes may implicate susceptibility to multiple sclerosis (MS) is supported by an increasing number of case reports on Leber's hereditary optic neuropathy (LHON)-associated mitochondrial DNA (mtDNA) point mutations in patients with MS. A number of mtDNA mutations with primary pathogeni...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000075518
更新日期:2004-01-01 00:00:00
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journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116841
更新日期:1992-01-01 00:00:00
abstract::The report deals with the changes of brain functions in the course of traumatic apallic syndrome (TAS) by means of the EEG examination, in the classical way, and by computer analysis as well. The development of EEG changes during individual stages of the TAS is studied. The EEG examination was performed repeatedly in ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000116316
更新日期:1987-01-01 00:00:00
abstract::Leonardo da Vinci clearly observed and described capillaries. Using the microscope, Marcello Malpighi examined the brain and major organs to demonstrate their finer anatomical features. This led to his discovery in 1661, of capillaries that proved fundamental to our understanding of the vascular system in the brain an...
journal_title:European neurology
pub_type: 传,历史文章,杂志文章
doi:10.1159/000107974
更新日期:2007-01-01 00:00:00
abstract::An 18-year-old mongoloid girl (trisomy 21) of Asian descent presented two symptoms rarely associated with mongolism (Down's syndrome). (1) Brain stem calcification; the first case diagnosed in vivo in mongolism on computerized axial tomography. (2) Hallucinatory psychotic depression; the first case successfully treate...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000114963
更新日期:1978-01-01 00:00:00
abstract::We have recently observed a diffuse slowing of brain waves using serial quantitative electroencephalographic (qEEG) examinations in interferon (IFN)-alpha-treated chronic hepatitis C patients. However, it remains unclear how this alteration could be assessed. We evaluated the correlation between the qEEG changes and t...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000062997
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Mood disorder is a frequent complication of stroke. Comorbid depressive and anxiety disorders are very common, indicating that it is advisable to assess both disorders at the same time. The aim of the present study was to examine the prevalence of post-stroke depression (PSD) and poststroke anxiety (PSA) at ...
journal_title:European neurology
pub_type: 杂志文章
doi:10.1159/000332585
更新日期:2011-01-01 00:00:00
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journal_title:European neurology
pub_type: 杂志文章,评审
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更新日期:1998-10-01 00:00:00