Small-molecule type III secretion system inhibitors block assembly of the Shigella type III secreton.

abstract：:Acyl carrier protein was localized by immunoelectron microscopy in the cytoplasm of Escherichia coli. These data are inconsistent with the previous report of an association between acyl carrier protein and the inner membrane (H. Van den Bosch, J.R. Williamson, and P.R. Vagelos, Nature [London] 228:338-341, 1970). More...

journal_title：Journal of bacteriology

authors： Jackowski S,Edwards HH,Davis D,Rock CO

更新日期：1985-04-01 00:00:00

abstract：:The ToxR protein of Vibrio cholerae regulates the expression of several virulence factors that play important roles in the pathogenesis of cholera. Previous experiments with ToxR-alkaline phosphatase (ToxR-PhoA) fusion proteins suggested a model for gene regulation in which the inactive form of ToxR was a monomer and ...

journal_title：Journal of bacteriology

authors： Ottemann KM,Mekalanos JJ

更新日期：1996-01-01 00:00:00

abstract：:Protein and mRNA levels of heat-labile enterotoxin (LT) of Escherichia coli are highest at 37 degrees C, and they decrease gradually as temperature is decreased. This temperature effect is eliminated in an Hns- mutant. Deletion of portions of DNA coding for the LT A subunit also results in an increase in LT expression...

journal_title：Journal of bacteriology

authors： Trachman JD,Maas WK

更新日期：1998-07-01 00:00:00

abstract：:The strict human pathogen Neisseria gonorrhoeae is exposed to oxidative damage during infection. N. gonorrhoeae has many defenses that have been demonstrated to counteract oxidative damage. However, recN is the only DNA repair and recombination gene upregulated in response to hydrogen peroxide (H(2)O(2)) by microarray...

journal_title：Journal of bacteriology

authors： Stohl EA,Seifert HS

更新日期：2006-11-01 00:00:00

abstract：:Flac mutants have been isolated in Escherichia coli K-12 which carry dominant mutations resulting in insensitivity to transfer inhibition by the Fin(+) I-like plasmid R62. These mutants were still sensitive to transfer inhibition by the fin(+) F-like plasmid R100 and, conversely, FlactraO(-) and traP(-) mutants, which...

journal_title：Journal of bacteriology

authors： Willetts NS,Paranchych W

更新日期：1974-10-01 00:00:00

abstract：:The specificity of the growth requirement of Methanobacterium ruminantium strain M1 for a new coenzyme, 2-mercaptoethanesulfonic acid (HS--CoM), was examined. A variety of derivatives, analogs, and potential biosynthetic precursors of coenzyme M were tested; only a restricted range of thioether, thioester, and thiocar...

journal_title：Journal of bacteriology

authors： Balch WE,Wolfe RS

更新日期：1979-01-01 00:00:00

abstract：:Gram-negative bacteria acquire ferric siderophores through TonB-dependent outer membrane transporters (TBDT). By fluorescence spectroscopic hgh-throughput screening (FLHTS), we identified inhibitors of TonB-dependent ferric enterobactin (FeEnt) uptake through Escherichia coli FepA (EcoFepA). Among 165 inhibitors found...

journal_title：Journal of bacteriology

authors： Nairn BL,Eliasson OS,Hyder DR,Long NJ,Majumdar A,Chakravorty S,McDonald P,Roy A,Newton SM,Klebba PE

更新日期：2017-04-25 00:00:00

abstract：:The peptidoglycan cell wall determines the shape and structural integrity of a bacterial cell. Class B penicillin-binding proteins (PBPs) carry a transpeptidase activity that cross-links peptidoglycan strands via their peptide side chains, and some of these proteins are directly involved in cell shape determination. N...

journal_title：Journal of bacteriology

authors： Wei Y,Havasy T,McPherson DC,Popham DL

更新日期：2003-08-01 00:00:00

abstract：:The potent tumor-promoting agent croton oil, which has been shown previously to be strongly mitogenic in mammalian cells, stimulates cell division in snake mutants of the blue-green bacterium Agmenellum quadruplicatum. ...

journal_title：Journal of bacteriology

authors： Ingram LO,Fisher WD

更新日期：1973-05-01 00:00:00

abstract：:Eight mutants of Bacillus subtilis deficient in xylan utilization were isolated and characterized genetically and biochemically. Each mutant was obtained independently after nitrosoguanidine mutagenesis. All of the analyzed mutations were shown to be linked. Reciprocal transformation crosses revealed the existence of ...

journal_title：Journal of bacteriology

authors： Roncero MI

更新日期：1983-10-01 00:00:00

abstract：:Ralston, D. J. (University of California, Berkeley) and M. D. Perry. Inhibitory action of phage K on staphylococcal dehydrogenases. II. Its possible relationship to sensitization and cell lysis. J. Bacteriol. 86:740-748. 1963.-By measuring the reduction of the dye triphenyl tetrazolium chloride to the insoluble red fo...

journal_title：Journal of bacteriology

authors： RALSTON DJ,PERRY MD

更新日期：1963-10-01 00:00:00

abstract：:The gene tyrP, which codes for a component of the tyrosine-specific transport system, has been localized on the Escherichia coli K-12 chromosome at min 42. A tyrP-lac operon fusion was constructed and used to isolate mutants that have altered expression from the tyrP promoter. All putative tyrP operator mutations were...

journal_title：Journal of bacteriology

authors： Kasian PA,Pittard J

更新日期：1984-10-01 00:00:00

abstract：:The penicillin-binding proteins (PBPs) of 209 cell division (or growth) temperature-sensitive mutants of Streptococcus faecium were analyzed in this study. A total of nine strains showed either constitutive or temperature-sensitive conditional damage in the PBPs. Analysis of these nine strains yielded the following re...

journal_title：Journal of bacteriology

authors： Canepari P,Lleò MM,Fontana R,Satta G

更新日期：1987-06-01 00:00:00

abstract：:The reduction of bisulfite by Desulfovibrio vulgaris was investigated. Crude extracts reduced bisulfite to sulfide without the formation (detection) of any intermediates such as trithionate or thiosulfate. When the particulate fractions was removed from crude extracts by high-speed centrifugation, the soluble supernat...

journal_title：Journal of bacteriology

authors： Drake HL,Akagi JM

更新日期：1978-12-01 00:00:00

abstract：:CRM 228 (T. Uchida, A. M. Pappenheimer, and R. Greany, J. Biol. Chem. 248:3838-3844, 1973), a mutant form of diphtheria toxin which completely lacks ADP-ribosyltransferase activity, contains five amino acid substitutions. The two amino acid changes that fall within the A chain of the toxin (G79D and E162K) were separa...

journal_title：Journal of bacteriology

authors： Johnson VG,Nicholls PJ

更新日期：1994-08-01 00:00:00

abstract：:A plasmid, R773, which confers resistance to arsenic compounds, is transmissible between strains of Escherichia coli. It is a member of compatibility group F(1). ...

journal_title：Journal of bacteriology

authors： Hedges RW,Baumberg S

更新日期：1973-07-01 00:00:00

abstract：:Recently, a new type of K+ transporter, Ktr, has been identified in the bacterium Vibrio alginolyticus (T. Nakamura, R. Yuda, T. Unemoto, and E. P. Bakker, J. Bacteriol. 180:3491-3494, 1998). The Ktr transport system consists of KtrB, an integral membrane subunit, and KtrA, a subunit peripherally bound to the cytoplas...

journal_title：Journal of bacteriology

authors： Holtmann G,Bakker EP,Uozumi N,Bremer E

更新日期：2003-02-01 00:00:00

abstract：:An apparatus has been developed in which bacterial growth can be measured very precisely over short intervals of time. Its precision is presented and used to assess the constancy of growth in batch culture. Under certain conditions, i.e., Luria broth or 0.2% glucose-M9 medium at very low cell densities, the specific g...

journal_title：Journal of bacteriology

authors： Wang CH,Koch AL

更新日期：1978-12-01 00:00:00

abstract：:During sporulation, the Bacillus subtilis transcription factor sigmaK is activated by regulated proteolytic processing. I have used a system that facilitates the analysis of the contributions of a modified form of the processing enzyme, SpoIVFB-GFP, and the regulatory proteins BofA and SpoIVFA to the conversion of pro...

journal_title：Journal of bacteriology

authors： Resnekov O

更新日期：1999-09-01 00:00:00

abstract：:The ftsZ gene of Escherichia coli, which lies in a cluster of cell division genes at 2 min on the genetic map, codes for a protein which is thought to play a key role in triggering cell division. Using an ftsZ::lacZ operon fusion, we have studied the transcription of the ftsZ gene under conditions in which cell divisi...

journal_title：Journal of bacteriology

authors： Robin A,Joseleau-Petit D,D'Ari R

更新日期：1990-03-01 00:00:00

abstract：:Eighty-seven different enterobacteria and pseudomonas strains were examined for the presence of extrachromosomal deoxyribonucleic acid (DNA). Thirty-four strains contained closed circular DNA by the ethidium bromide CsCl density technique. Extrachromosomal DNA was most frequent in Escherichia and Klebsiella strains. T...

journal_title：Journal of bacteriology

authors： Christiansen C,Christiansen G,Bak AL,Stenderup A

更新日期：1973-04-01 00:00:00

abstract：:Bacterial biofilms are important in natural settings, biotechnology, and medicine. However, regulation of biofilm development and its persistence in different niches is complex and only partially understood. One key step during the biofilm life cycle is dispersal, when motile cells abandon the mature biofilm to spread...

journal_title：Journal of bacteriology

authors： Bartolini M,Cogliati S,Vileta D,Bauman C,Rateni L,Leñini C,Argañaraz F,Francisco M,Villalba JM,Steil L,Völker U,Grau R

更新日期：2018-12-20 00:00:00

abstract：:After UV irradiation, Escherichia coli uvrA mutant cells show higher survival on minimal than on rich growth medium, i.e., they show minimal-medium recovery. This effect of rich growth medium on survival is not observed in a uvrA mutant carrying an mmrA1 mutation, and the uvrA mmrA strain showed the same survival rate...

journal_title：Journal of bacteriology

authors： Sharma RC,Sargentini NJ,Smith KC

更新日期：1983-05-01 00:00:00

abstract：:In Azotobacter vinelandii, activation of nif gene expression by the transcriptional regulatory enhancer binding protein NIFA is controlled by the sensor protein NIFL in response to changes in levels of oxygen and fixed nitrogen in vivo. NIFL is a novel redox-sensing flavoprotein which is also responsive to adenosine n...

journal_title：Journal of bacteriology

authors： Money T,Jones T,Dixon R,Austin S

更新日期：1999-08-01 00:00:00

abstract：:The biological activity of Odontomyces viscosus, which has been reported to cause periodontal disease in hamsters, was examined. The microorganism was cultured anaerobically in Brain Heart Infusion broth, and the cells were harvested. The washed cells were injected intradermally into the abdomen of rabbits. After 72 h...

journal_title：Journal of bacteriology

authors： Schuster GS,Hayashi JA,Bahn AN

更新日期：1967-01-01 00:00:00

abstract：:The nucleotide sequence of tnaB of the tryptophanase operon of Escherichia coli is presented. TnaB is a tryptophan-specific permease that is homologous to Mtr, a second tryptophan-specific permease, and to TyrP, a tyrosine-specific permease. Each member of this family appears to contain 11 membrane-spanning domains. ...

journal_title：Journal of bacteriology

authors： Sarsero JP,Wookey PJ,Gollnick P,Yanofsky C,Pittard AJ

更新日期：1991-05-01 00:00:00

abstract：:A reversal in the relative amounts of the two major species of tyrosine transfer ribonucleic acid (tRNATyr) (I and II) has been previously observed by others during the development of Bacillus subtilis. These species have been purified by benzoylated diethylaminoethyl-cellulose chromatography and were shown to differ ...

journal_title：Journal of bacteriology

authors： Menichi B,Heyman T

更新日期：1976-07-01 00:00:00

abstract：:Grunberg, E. (Hoffman-La Roche, Inc., Nutley, N.J.), and R. Cleeland. Fluorescence and viability of Proteus mirabilis stained directly with fluorescein isothiocyanate. J. Bacteriol. 92:23-27. 1966.-Washed cell suspensions of Proteus mirabilis, under the proper conditions, stained well with fluorescein isothiocyanate w...

journal_title：Journal of bacteriology

authors： Grunberg E,Cleeland R

更新日期：1966-07-01 00:00:00

abstract：:Pseudomonas oleovorans contains an isomerase which catalyzes the cis-trans conversion of the abundant unsaturated membrane fatty acids 9-cis-hexadecenoic acid (palmitoleic acid) and 11-cis-octadecenoic acid (vaccenic acid). We purified the isomerase from the periplasmic fraction of Pseudomonas oleovorans. The molecula...

journal_title：Journal of bacteriology

authors： Pedrotta V,Witholt B

更新日期：1999-05-01 00:00:00

abstract：:Strains carrying either the polA1 or resA1 mutation are deficient in DNA polymerase I, and the polA1 and resA1 mutations do not complement in merozygotes. The effect of these mutations in otherwise identical genetic backgrounds was studied: after ultraviolet irradiation both strains degrade their DNA more rapidly and ...

journal_title：Journal of bacteriology

authors： Glickman BW,van Sluis CA,van der Maas G,Rörsch A

更新日期：1973-06-01 00:00:00