Abstract:
:Epidemiologic literatures suggest that temporomandibular joint disorders (TMD) are more prevalent in women than in men. It is affecting approximately 7-15% of the adult population in North America, and 80% of patients treated for TMD are women. The severity of symptoms is also related to the age of the patients. The gender and age distribution of TMD suggests a possible link between its pathogenesis and estrogen. It has been reported that estrogen could influence the development, restitution and metabolism of the temporomandibular joint and associated structures such as bone, cartilage and articular disc. Estrogen can also influence the regulative mechanism of pain. In this article, we will use the hypothesis that the overwhelming majority of patients treated for temporomandibular disorders are women and use the available literature to examine the role of estrogens in TMD.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Wang J,Chao Y,Wan Q,Zhu Zdoi
10.1016/j.mehy.2008.05.011subject
Has Abstractpub_date
2008-10-01 00:00:00pages
564-7issue
4eissn
0306-9877issn
1532-2777pii
S0306-9877(08)00232-6journal_volume
71pub_type
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