Abstract:
BACKGROUND:The exact distribution of periprostatic autonomic nerves is under debate. OBJECTIVE:To study the topographical anatomy of autonomic nerves of the periprostatic tissue and the capsule of the prostate (CAP). DESIGN, SETTING, AND PARTICIPANTS:Whole-mount sections of 30 prostates from patients having undergone non-nerve-sparing radical prostatectomy were investigated after immunohistochemical nerve staining. Sections from the base, the middle, and the apex were evaluated. All sections were divided into 12 sectors, which were combined into the following regions: ventral, ventrolateral, dorsolateral, and dorsal. MEASUREMENTS:Quantification of periprostatic and capsular nerves was performed within the sectors. Computerised planimetry of the total periprostatic nerve surface area of each region was performed (Image-J software, Wayne Rasband, National Institute of Health, USA). RESULTS AND LIMITATIONS:A total of 3514, 3860, and 3902 periprostatic nerves was counted at the base, the middle, and the apex, respectively (p=0.068). The ratio of periprostatic nerves to capsular nerves was 3.6, 2.1, and 1.9 at the base, the middle, and the apex, respectively (p=0.004). Computerised planimetry revealed a significant decrease in total nerve surface area from the base over the middle towards the apex, with 241.79, 133.64, and 89.50mm(2) (p=0.004). The percentage of total nerve surface area was highest dorsolaterally (84.1%, 75.1%, and 74.5% at base, middle, and apex, respectively) but variable: Up to 39.9% of nerve surface area was found ventrolaterally and up to 45.5% in the dorsal position. The study is limited by the fact that autonomic nerve distribution was only investigated from the base to the apex of the prostate. CONCLUSIONS:Periprostatic nerve distribution is variable, with a high percentage of nerves in the ventrolateral and dorsal positions. Total periprostatic nerve surface area decreases from the base towards the apex due to nerves leaving the NVB branching into the prostate. This can only be discovered by nerve planimetry, not by quantification.
journal_name
Eur Uroljournal_title
European urologyauthors
Ganzer R,Blana A,Gaumann A,Stolzenburg JU,Rabenalt R,Bach T,Wieland WF,Denzinger Sdoi
10.1016/j.eururo.2008.04.018subject
Has Abstractpub_date
2008-08-01 00:00:00pages
353-60issue
2eissn
0302-2838issn
1873-7560pii
S0302-2838(08)00438-7journal_volume
54pub_type
杂志文章相关文献
EUROPEAN UROLOGY文献大全abstract::An alternative to conventional laparoscopy when looking for virtually scarless surgery is mini-laparoscopy, a reproducible technique that preserves the triangulation concept. A drawback of this approach is the poor image quality provided by mini-scopes. The introduction of the SPIEs technology, a novel endoscopic came...
journal_title:European urology
pub_type: 杂志文章,评审
doi:10.1016/j.eururo.2014.06.001
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Despite the documented survival benefit conferred by neoadjuvant (NAC) and adjuvant chemotherapy (AC), there has been a slow adoption of guideline recommendations for the use of perioperative chemotherapy (POC) in patients with muscle-invasive bladder cancer (MIBC). OBJECTIVE:To evaluate temporal trends in ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2014.01.009
更新日期:2015-01-01 00:00:00
abstract::Formalin-fixed, paraffin-embedded specimens from 91 primary transitional cell cancers (TCC) of the urinary bladder were stained with a monoclonal antibody to c-erb B-2 oncoprotein. Twelve percent (11/91) of the TCC stained for c-erb b-2 oncoprotein, and in 4% (4/91) of cases, the expression was graded as moderate or h...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000471706
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:To report on recent findings and new concepts in the remodeling of the capillary architecture in the precursors of prostate cancer. METHODS:Immunohistochemical methods have been adopted in prostate cancer and in its precursors (prostatic intra-epithelial neoplasia) to investigate capillary pattern changes-wh...
journal_title:European urology
pub_type: 杂志文章,评审
doi:10.1159/000474169
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:The evolution of resistant pathogens is a worldwide health crisis and adherence to European Association of Urology (EAU) guidelines on antibiotic prophylaxis may be an important way to improve antibiotic stewardship and reduce patient harm and costs. OBJECTIVE:To evaluate the prevalence of antibiotic-resist...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2015.05.010
更新日期:2016-02-01 00:00:00
abstract::Antitumor effect of recombinant human tumor necrosis factor alpha (TNF) alone or in combination with various anticancer chemotherapeutic agents was tested using an in vitro antiproliferative assay on four human renal carcinoma cell lines (VMRC-RCW, VMRC-RCZ, Caki-1 and A-498). When the dose-dependent effect of TNF was...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000473628
更新日期:1991-01-01 00:00:00
abstract::In a randomized study of 200 consecutive patients undergoing transurethral prostatectomy (TURP), the combination of internal urethrotomy and TURP (the trial group) was compared with TURP alone (the control group) with regard to the development of urethral strictures postoperatively. Three months after resection, 14% i...
journal_title:European urology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000471587
更新日期:1989-01-01 00:00:00
abstract::9 male patients with rectourethral fistula were treated. Fistulae were congenital in 1 case, iatrogenic in 6 cases and traumatic in 2 cases. In 8 cases we used an abdominoperineal approach with omentoplasty or peritoneal flap; in 1 case a perineal approach was made. In 2 cases it was also necessary to use a transpubic...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000472547
更新日期:1985-01-01 00:00:00
abstract::The three diffuse projection systems arising in the brainstem, that is, noradrenergic projection originating in the locus coeruleus, serotonergic projection from the dorsal raphe nucleus, and cholinergic projection from neurons gathering in the laterodorsal tegmental nucleus and scattering in the pedunculopontine tegm...
journal_title:European urology
pub_type: 杂志文章,评审
doi:10.1159/000052235
更新日期:1998-01-01 00:00:00
abstract::Prostate cancer is the most common malignancy found in males; however, little is as yet known regarding what initiates the disease. The incidence is highest among American Blacks and lowest in the East Asian population. Subtypes of the disease include familial clustering and a hereditary form (9%) supporting genetic e...
journal_title:European urology
pub_type: 杂志文章,评审
doi:10.1159/000019910
更新日期:1999-01-01 00:00:00
abstract:CONTEXT:Squamous cell carcinoma (SCC) of the penis is a relatively rare but ominous disease. OBJECTIVE:To present a condensed version of the updated 2009 European Association of Urology (EAU) guidelines on penile SCC. EVIDENCE ACQUISITION:We performed a literature search of new data available up to December 2009. No ...
journal_title:European urology
pub_type: 杂志文章,实务指引
doi:10.1016/j.eururo.2010.01.039
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:We retrospectively evaluated the safety, efficacy and patient satisfaction following the male sling procedure for stress urinary incontinence. MATERIALS AND METHODS:Forty-six patients, with a median age of 67 years, underwent the perineal male sling procedure for stress urinary incontinence. Radical retropub...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2004.06.021
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:Robot-assisted radical cystectomy (RARC) has evolved as a minimally invasive alternative to open radical cystectomy for patients with invasive bladder cancer. OBJECTIVE:We sought to define the learning curve for RARC by evaluating results from a multicenter, contemporary, consecutive series of patients who ...
journal_title:European urology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.eururo.2010.04.024
更新日期:2010-08-01 00:00:00
abstract::During an 18-month period, 200 male infertility patients had scrotal sonography examination. Fifty-seven percent showed abnormal sonogram; such as epididymitis, epididymo-orchitis, orchitis, varicocele, spermatocele, epididymal cyst and undescended testis. Among all lesions, infection was the commonest finding. There ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000471634
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVES:To determine whether there is a significant correlation between age and prostate-specific antigen (PSA) and to explain the wide literature variations in its value. METHODS:Two different groups were studied; the first (n = 403) consisted of patients undergoing prostatectomies for symptomatic benign prostatic...
journal_title:European urology
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVES:Prostate cancer is the most frequent cancer among men in the US. Histological grading is an important part of the diagnostic evaluation aside from clinical staging and serum PSA. The most commonly used grading system is the one described by Gleason. From a prognostic point of view, it is of considerable inte...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000019578
更新日期:1998-01-01 00:00:00
abstract::Preliminary data suggest that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with higher mortality among cancer patients, particularly in those on systemic therapy. It is unclear whether this applies to patients receiving immune checkpoint inhibitors (ICIs). In this case series, 7...
journal_title:European urology
pub_type:
doi:10.1016/j.eururo.2020.05.024
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Laparoendoscopic single-site (LESS) surgery is challenging. To help overcome current technical and ergonomic limitations, the da Vinci robotic platform can be applied to LESS. OBJECTIVES:Our aim was to describe the surgical technique and to report the early outcomes of robotic LESS (R-LESS) radical prostate...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2010.06.040
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVES:To report the utilization of a modified Endo GIA vascular stapler to obtain the full length of the renal vein during transperitoneal laparoscopic live donor right nephrectomy. METHODS:We used a modified Endo GIA stapler, in which the triple staggered rows of staples were removed from the kidney donor side t...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2006.11.052
更新日期:2007-05-01 00:00:00
abstract:BACKGROUND:One of the most effective and popular current procedures for the surgical treatment of stress urinary incontinence (SUI) is tension-free midurethral slings. OBJECTIVE:To evaluate the outcomes of women with retropubic tension-free vaginal tape (TVT) for urodynamic stress incontinence (USI) after 10-yr follow...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2012.01.038
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVES:Preoperative low serum testosterone (TS) level has been reported to be associated with adverse pathologic results in patients with clinically localized prostate cancer (pCA) treated with radical prostatectomy (RP). However, prior studies failed to show prognostic impact of preoperative low TS in these patien...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2007.03.052
更新日期:2007-09-01 00:00:00
abstract::The bulbocavernosus reflex can be elicited either by penile or urethral stimulation. The mean signal transit time after electrostimulation of the dorsal penile nerve to evoked response in the anal sphincter (35 msec) was only half the signal transit time after stimulation in the posterior urethra (60 msec). Thus, the ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000473058
更新日期:1979-01-01 00:00:00
abstract::Aminoglutethimide (AG) and hydrocortisone (HC) were given to 20 patients with advanced prostatic cancer resistant to conventional hormonal therapy. Most patients had painful bone metastases and were heavily pretreated. 12 of 16 patients required narcotic analgetics. 8 of 20 were bedridden. AG + HC produced relief of b...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000472913
更新日期:1988-01-01 00:00:00
abstract:CONTEXT:Conservative therapies for Peyronie's disease (PD) aim to treat early-stage disease by improving clinical outcomes such as penile curvature, penile length erectile dysfunction, and pain. OBJECTIVE:To summarise the available evidence regarding injection and mechanical therapies for PD treatment. EVIDENCE ACQUI...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2018.07.005
更新日期:2018-12-01 00:00:00
abstract::Two hundred and seventeen consecutive patients with superficial bladder cancer stages Ta-T1 were analyzed for survival and prognostic factors. The overall 5-year survival was 88 +/- 5.3%. Factors that impacted significantly on survival were: grade of anaplasia (GI 92 +/- 5.9% vs. GII 87 +/- 7.5% vs. GIII 68 +/- 20.7%;...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000471697
更新日期:1991-01-01 00:00:00
abstract::The authors present their experience (24 children) with the endoscopic subureteral injection of Teflon paste in the correction of secondary vesicoureteral reflux: reimplantation failure; ureterocele; obstructive bladder; exstrophy; postchemocystitis, and Hutch's diverticulum. Of these 24 cases (31 refluxing ureters), ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000464067
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Several studies have shown that robot-assisted laparoscopic radical prostatectomy (RALP) is feasible, with favorable complication rates and short hospital times. However, the early recovery of urinary continence remains a challenge to be overcome. OBJECTIVE:We describe our technique of periurethral retropub...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2009.06.007
更新日期:2009-09-01 00:00:00
abstract::Among 169 patients treated for supeficial bladder tumor with 150 mg Pasteur-strain bacillus Calmette-Guérin (BCG) intravesical instillation, 5 cases of 'BCGitis' were observed, i.e. a severe systemic BCG infection with bronchopulmonary lesions and granulomatous hepatitis. In 4 cases, the complications appeared at the ...
journal_title:European urology
pub_type: 杂志文章
doi:10.1159/000471561
更新日期:1989-01-01 00:00:00
abstract::A randomised trial of robotic and open prostatectomy commenced in October 2010 and is progressing well. Clinical and quality of life outcomes together with economic costs to individuals and the health service are being examined critically to compare outcomes. ...
journal_title:European urology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.eururo.2013.10.031
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Over the years, several techniques for performing robot-assisted prostatectomy have been implemented in an effort to achieve optimal oncological and functional outcomes. OBJECTIVE:To provide an evidence-based description and video-based illustration of currently available dissection techniques for robotic p...
journal_title:European urology
pub_type: 杂志文章
doi:10.1016/j.eururo.2020.07.017
更新日期:2020-10-01 00:00:00