当前位置： SCI文献检索 > EUROPEAN UROLOGY期刊下所有文献 > Combined effect of tumor necrosis factor alpha and anticancer chemotherapeutic agents against human renal carcinoma cell lines.

Combined effect of tumor necrosis factor alpha and anticancer chemotherapeutic agents against human renal carcinoma cell lines.

Abstract：

:Antitumor effect of recombinant human tumor necrosis factor alpha (TNF) alone or in combination with various anticancer chemotherapeutic agents was tested using an in vitro antiproliferative assay on four human renal carcinoma cell lines (VMRC-RCW, VMRC-RCZ, Caki-1 and A-498). When the dose-dependent effect of TNF was studied, none of the four cell lines showed a 50% or more inhibition even at a concentration of 10,000 U/ml of TNF, so that the susceptibility to TNF was low. An enhancing effect of TNF on the cytotoxic effect of almost all the chemotherapeutic agents tested was observed against VMRC-RCZ and A-498. Against VMRC-RCW and Caki-1, the combination of TNF with the chemotherapeutic agents did not result in an enhancing effect. Mitomycin C showed an enhancing effect of TNF against all four cell lines. These results suggested that the combined treatment of TNF with chemotherapeutic agents may have favorable results in clinical trials.

journal_name

Eur Urol

journal_title

European urology

authors

Ikemoto S,Hayahara N,Wada S,Nishio S,Maekawa M

doi

10.1159/000473628

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

236-9

issue

3

eissn

0302-2838

issn

1873-7560

journal_volume

19

pub_type

杂志文章

相关文献

EUROPEAN UROLOGY文献大全
  • Brainstem neural mechanisms of sleep and wakefulness.

    abstract：:The three diffuse projection systems arising in the brainstem, that is, noradrenergic projection originating in the locus coeruleus, serotonergic projection from the dorsal raphe nucleus, and cholinergic projection from neurons gathering in the laterodorsal tegmental nucleus and scattering in the pedunculopontine tegm...

    journal_title：European urology

    pub_type： 杂志文章,评审

    doi：10.1159/000052235

    authors： Kayama Y,Koyama Y

    更新日期：1998-01-01 00:00:00

  • Prostate-specific antigen and age. Is there a correlation? And why does it seem to vary?

    abstract：OBJECTIVES:To determine whether there is a significant correlation between age and prostate-specific antigen (PSA) and to explain the wide literature variations in its value. METHODS:Two different groups were studied; the first (n = 403) consisted of patients undergoing prostatectomies for symptomatic benign prostatic...

    journal_title：European urology

    pub_type： 杂志文章

    doi：

    authors： Kirollos MM

    更新日期：1996-01-01 00:00:00

  • The early detection and diagnosis of bladder cancer: a critical review of the options.

    abstract：:Bladder cancer has a high worldwide incidence matched by a tendency to recur, necessitating close and regular follow-up. Current methods of investigation of bladder cancer involve cystoscopy, ultrasound scanning and contrast urography, with additional information provided by cytology. These methods, although having a ...

    journal_title：European urology

    pub_type： 杂志文章,评审

    doi：10.1159/000052519

    authors： Saad A,Hanbury DC,McNicholas TA,Boustead GB,Woodman AC

    更新日期：2001-06-01 00:00:00

  • Best practices in robot-assisted radical cystectomy and urinary reconstruction: recommendations of the Pasadena Consensus Panel.

    abstract：CONTEXT:Robot-assisted surgery is increasingly used for radical cystectomy (RC) and urinary reconstruction. Sufficient data have accumulated to allow evidence-based consensus on key issues such as perioperative management, comparative effectiveness on surgical complications, and oncologic short- to midterm outcomes. O...

    journal_title：European urology

    pub_type： 共识发展会议,杂志文章,实务指引,评审

    doi：10.1016/j.eururo.2014.12.009

    authors： Wilson TG,Guru K,Rosen RC,Wiklund P,Annerstedt M,Bochner BH,Chan KG,Montorsi F,Mottrie A,Murphy D,Novara G,Peabody JO,Palou Redorta J,Skinner EC,Thalmann G,Stenzl A,Yuh B,Catto J,Pasadena Consensus Panel.

    更新日期：2015-03-01 00:00:00

  • Five-year results of a randomized trial comparing retropubic and transobturator midurethral slings for stress incontinence.

    abstract：BACKGROUND:Midurethral slings have become the most preferred surgical treatment for female urinary incontinence. OBJECTIVE:To compare the efficacy and safety of two midurethral sling procedures with a different technique of sling insertion 5 yr after intervention. DESIGN, SETTING, AND PARTICIPANTS:Multicenter randomi...

    journal_title：European urology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.eururo.2014.01.031

    authors： Laurikainen E,Valpas A,Aukee P,Kivelä A,Rinne K,Takala T,Nilsson CG

    更新日期：2014-06-01 00:00:00

  • Safety study of umbilical single-port laparoscopic radical prostatectomy with a new DuoRotate system.

    abstract：BACKGROUND:Laparoendoscopic single-site (LESS) radical prostatectomy (RP) has been performed through different approaches. A new DuoRotate manual system developed by Richard Wolf (KeyPort; Richard Wolf GmbH, Knittlingen, Germany) can be applied to RP. OBJECTIVES:Our aim was to describe the surgical technique and repor...

    journal_title：European urology

    pub_type： 杂志文章

    doi：10.1016/j.eururo.2012.04.043

    authors： Cáceres F,Cabrera PM,García-Tello A,García-Mediero JM,Angulo JC

    更新日期：2012-12-01 00:00:00

  • Adjuvant chemotherapy in invasive bladder cancer: a systematic review and meta-analysis of individual patient data Advanced Bladder Cancer (ABC) Meta-analysis Collaboration.

    abstract：OBJECTIVES:To evaluate the effect of adjuvant chemotherapy in invasive bladder cancer. METHODS:: We conducted a systematic review and meta-analysis of updated individual patient data from all available randomised controlled trials comparing local treatment plus adjuvant chemotherapy versus the same local treatment alo...

    journal_title：European urology

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.eururo.2005.04.005

    authors： Advanced Bladder Cancer (ABC) Meta-analysis Collaboration.

    更新日期：2005-08-01 00:00:00

  • Posterior hypospadias repair: a new technical approach. Mobilization of the urethral plate and duplay urethroplasty.

    abstract：:We describe our experience with a new technique of complete repair of severe posterior hypospadias in one stage. The operative technique includes some innovative points: penile straightening is realized by urethral mobilization (without detaching it from the glans) to excise the chordee, and then urethroplasty accordi...

    journal_title：European urology

    pub_type： 杂志文章

    doi：10.1159/000474741

    authors： Montfort G,Bretheau D,di Benedetto V,Bankole R

    更新日期：1992-01-01 00:00:00

  • Pattern of relapse after first line treatment of advanced stage germ-cell tumors.

    abstract：OBJECTIVES:We performed a retrospective analysis of first relapses after cisplatin-based chemotherapy in patients with advanced germ-cell tumors, in order to better define the appropriate follow-up. METHODS:These patients were treated between 1986 and 1998 in two institutions. They were either followed after first-lin...

    journal_title：European urology

    pub_type： 杂志文章

    doi：10.1016/j.eururo.2005.06.018

    authors： Fléchon A,Culine S,Théodore C,Droz JP

    更新日期：2005-12-01 00:00:00

  • A Multicohort Open-label Phase II Trial of Bipolar Androgen Therapy in Men with Metastatic Castration-resistant Prostate Cancer (RESTORE): A Comparison of Post-abiraterone Versus Post-enzalutamide Cohorts.

    abstract：BACKGROUND:Cyclic high-dose testosterone injections, also known as bipolar androgen therapy (BAT), is a novel treatment strategy for patients with metastatic castration-resistant prostate cancer (mCRPC). BAT has shown clinical activity in prior studies enrolling men with mCRPC and may potentially restore sensitivity to...

    journal_title：European urology

    pub_type： 杂志文章

    doi：10.1016/j.eururo.2020.06.042

    authors： Markowski MC,Wang H,Sullivan R,Rifkind I,Sinibaldi V,Schweizer MT,Teply BA,Ngomba N,Fu W,Carducci MA,Paller CJ,Marshall CH,Eisenberger MA,Luo J,Antonarakis ES,Denmeade SR

    更新日期：2020-07-02 00:00:00

  • Radical economic surgery and antiandrogenic therapy in management of prostatic cancer.

    abstract：:The treatment of early stage prostatic cancer with retropubic radical prostatectomy, pelvic lymphadenectomy and antiandrogenic therapy is reported. Out of 22 patients operated in the past 9 years, none died because of the tumor and metastases appeared in 1 patient only. The latter showed a microscopic seminal vesicle ...

    journal_title：European urology

    pub_type： 杂志文章

    doi：10.1159/000473352

    authors： Giuliani L

    更新日期：1980-01-01 00:00:00

  • A placebo-controlled comparison of the efficiency of triple- and monotherapy in category III B chronic pelvic pain syndrome (CPPS).

    abstract：OBJECTIVES:To perform a prospective, placebo-controlled study to examine the efficacy of alpha-blocker compared with triple therapy (alpha-blocker, anti-inflammatory, and muscle relaxant) in the treatment of Category IIIB chronic pelvic pain syndrome (Category IIIB CPPS). MATERIALS AND METHODS:The study was conducted ...

    journal_title：European urology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.eururo.2006.09.036

    authors： Tuğcu V,Taşçi AI,Fazlioğlu A,Gürbüz G,Ozbek E,Sahin S,Kurtuluş F,Cek M

    更新日期：2007-04-01 00:00:00

  • Tumour-associated antibodies against renal cell carcinomas detected by immunofluorescence.

    abstract：:Serum from 39 of 288 (13.5%) cancer patients contained antibodies detectable by immunofluorescence which reacted with frozen tumour sections from kidneys, prostate glands and ovaries. The serum did not react against areas of normal kidney taken from the same diseased organ. In comparison, 0.7% of normal persons and 3....

    journal_title：European urology

    pub_type： 杂志文章

    doi：

    authors： Ackermann R

    更新日期：1975-01-01 00:00:00

  • Prognostic value of Ki-67 expression in renal cell carcinomas.

    abstract：OBJECTIVE:The aim of the study was to determine the prognostic power of Ki-67 immunostaining in renal cell carcinomas (RCC). METHODS:Clinical follow-up data were reviewed in 111 RCC and the results of Ki-67 immunolabelling were correlated to standard prognostic factors and survival data of the patients. RESULTS:Ki-67...

    journal_title：European urology

    pub_type： 杂志文章

    doi：10.1159/000474482

    authors： Aaltomaa S,Lipponen P,Ala-Opas M,Eskelinen M,Syrjänen K

    更新日期：1997-01-01 00:00:00

  • Combination of diffusion-weighted magnetic resonance imaging and extended prostate biopsy predicts lobes without significant cancer: application in patient selection for hemiablative focal therapy.

    abstract：BACKGROUND:Significant cancer in contralateral sides of the prostate that was missed on prostate biopsy (PBx) is a concern in hemiablative focal therapy (FT) of prostate cancer (PCa). However, extended PBx, a common diagnostic procedure, has a limited predictive ability for lobes without significant cancer. OBJECTIVE:...

    journal_title：European urology

    pub_type： 杂志文章

    doi：10.1016/j.eururo.2012.10.010

    authors： Matsuoka Y,Numao N,Saito K,Tanaka H,Kumagai J,Yoshida S,Koga F,Masuda H,Kawakami S,Fujii Y,Kihara K

    更新日期：2014-01-01 00:00:00

  • Use of computerized cell image analysis to characterize cell nucleus populations from normal and neoplastic renal tissues.

    abstract：:We studied 55 renal tissue samples from 16 patients corresponding to normal (19 samples, group 1), low-grade (18 samples, group 2), and high-grade (18 samples, group 3) tumoral tissues. For this purpose, we used digital cell image analysis (the SAMBA 200 processor) to describe the morphonuclear patterns of Feulgen-sta...

    journal_title：European urology

    pub_type： 杂志文章

    doi：10.1159/000473605

    authors： vanden Houte K,Kiss R,de Prez C,Verhest A,Pasteels JL,van Velthoven R

    更新日期：1991-01-01 00:00:00

  • T lymphocytes infiltrating the bladder wall of patients with carcinoma of urinary bladder are in vivo activated.

    abstract：OBJECTIVES:This paper studies the phenotypical characteristics of the lymphocytes present in mononuclear cell (MNC) preparations from peripheral blood (PBMNC), lymph nodes (LNMNC), tumor bladder (TBMNC), and tumor-free bladder (TFBMNC) from patients with infiltrated transitional cell carcinoma (TCC) of the bladder and ...

    journal_title：European urology

    pub_type： 杂志文章

    doi：10.1159/000474509

    authors： Reyes E,Carballido J,Prieto A,Molto L,Manzano L,Alvarez-Mon M

    更新日期：1997-01-01 00:00:00

  • Gastrointestinal presentation of germ cell malignancy.

    abstract：OBJECTIVES:To summarize monoinstitutional experience with gastrointestinal (GI) presentations of germ cell malignancy and to review recent medical literature on this issue. METHODS:Retrospective review of 5 cases with advanced germ cell malignancy (testicular 2 and retroperitoneal 3) and involvement of the upper GI tr...

    journal_title：European urology

    pub_type： 杂志文章,评审

    doi：10.1159/000020368

    authors： Nord C,Fosså SD,Giercksky KE

    更新日期：2000-12-01 00:00:00

  • Bladder neck wrap: a modified fascial sling in treatment of incontinence in myelomeningocele patients.

    abstract：:In a large percentage of myelomeningocele patients the bladder neck and posterior urethra are widely open. Pubovaginal or puboprostatic sling has been proposed to achieve continence. Herein, a further modification of the fascial sling is presented. By wrapping the sling around the bladder neck more coaptation is achie...

    journal_title：European urology

    pub_type： 杂志文章

    doi：10.1159/000475315

    authors： Ghoniem GM

    更新日期：1994-01-01 00:00:00

  • Peyronie's disease: prevalence and association with cigarette smoking. A multicenter population-based study in men aged 50-69 years.

    abstract：OBJECTIVES:We present a multicenter, population-based epidemiological survey aimed at assessing the prevalence of Peyronie's disease (PD) and its potential risk factors in the general population. METHODS:In each of the ten centers throughout Italy, a uroandrologist contacted all the men in the age range 50-69 years re...

    journal_title：European urology

    pub_type： 杂志文章,多中心研究

    doi：10.1159/000049830

    authors： La Pera G,Pescatori ES,Calabrese M,Boffini A,Colombo F,Andriani E,Natali A,Vaggi L,Catuogno C,Giustini M,Taggi F,SIMONA Study Group.

    更新日期：2001-11-01 00:00:00

  • The learning curve of robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium.

    abstract：BACKGROUND:Robot-assisted radical cystectomy (RARC) has evolved as a minimally invasive alternative to open radical cystectomy for patients with invasive bladder cancer. OBJECTIVE:We sought to define the learning curve for RARC by evaluating results from a multicenter, contemporary, consecutive series of patients who ...

    journal_title：European urology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.eururo.2010.04.024

    authors： Hayn MH,Hussain A,Mansour AM,Andrews PE,Carpentier P,Castle E,Dasgupta P,Rimington P,Thomas R,Khan S,Kibel A,Kim H,Manoharan M,Menon M,Mottrie A,Ornstein D,Peabody J,Pruthi R,Palou Redorta J,Richstone L,Schanne F

    更新日期：2010-08-01 00:00:00

  • Guidelines on erectile dysfunction.

    abstract：:The introduction of new oral therapies has completely changed the diagnostic and therapeutic approach to erectile dysfunction. A panel of experts in this field have developed guidelines for clinical evaluation and treatment based on the review of available scientific information. ...

    journal_title：European urology

    pub_type： 指南,杂志文章,实务指引

    doi：10.1016/s0302-2838(01)00008-2

    authors： Wespes E,Amar E,Hatzichristou D,Montorsi F,Pryor J,Vardi Y,European Association of Urology.

    更新日期：2002-01-01 00:00:00

  • Transient receptor potential vanilloid type 1 (TRPV1) expression changes from normal urothelium to transitional cell carcinoma of human bladder.

    abstract：OBJECTIVE:To investigate possible changes in the expression of the transient receptor potential vanilloid type 1 (TRPV1) from normal urothelium to transitional cell carcinoma (TCC) of human bladder. METHODS:Specimens from normal bladder (n=13, mean age 62 yrs), superficial TCC (n=16, mean age 62,4 yrs) and muscle inva...

    journal_title：European urology

    pub_type： 杂志文章

    doi：10.1016/j.eururo.2005.05.018

    authors： Lazzeri M,Vannucchi MG,Spinelli M,Bizzoco E,Beneforti P,Turini D,Faussone-Pellegrini MS

    更新日期：2005-10-01 00:00:00

  • Functional evaluation of bladder neck disease.

    abstract：:22 patients diagnosed as having bladder neck disease were evaluated retrospectively point of view. Urodynamic study including intravesical pressure, rectal pressure, intrinsic detrusor pressure and urine flow was performed in every case. A relation was established between the findings and the definite etiology. Two ur...

    journal_title：European urology

    pub_type： 杂志文章

    doi：

    authors： Romero-Maroto J,Tallada-Buñuel M,Verdú-Tartajo F,Perales-Cabanas L,Escudero-Barrilero A,Romero-Aguirre C

    更新日期：1982-01-01 00:00:00

  • A (-5, -7) proPSA based artificial neural network to detect prostate cancer.

    abstract：OBJECTIVE:The pro-forms of prostate specific antigen (-2,-5,-7 proPSA) and also %free PSA based artificial neural networks (ANN) have been suggested to enhance the discrimination between prostate cancer (PCa) and no evidence of malignancy (NEM). This study reports on the combined use of proPSA within a %free PSA based ...

    journal_title：European urology

    pub_type： 杂志文章

    doi：10.1016/j.eururo.2006.04.011

    authors： Stephan C,Meyer HA,Kwiatkowski M,Recker F,Cammann H,Loening SA,Jung K,Lein M

    更新日期：2006-11-01 00:00:00

  • Tumor collagenase-stimulating factor and tumor autocrine motility factor as tumor markers in bladder cancer--an update.

    abstract：:We have studied the role of combined measurements of tumor collagenase-stimulating factor (TCSF) and tumor autocrine motility factor (TAMF) in 83 first morning voids and 24-hour specimens in patients with bladder and renal cancer and control subjects. TCSF and TAMF were measured by immunoabsorption assay and motility ...

    journal_title：European urology

    pub_type： 杂志文章

    doi：10.1159/000474877

    authors： Javadpour N,Guirguis R

    更新日期：1992-01-01 00:00:00

  • A negative confirmatory biopsy among men on active surveillance for prostate cancer does not protect them from histologic grade progression.

    abstract：BACKGROUND:Many men (21-52%) are reported to have no cancer on the second, also known as the confirmatory, biopsy (B2) for prostate cancer active surveillance (AS). If these men had a reduced risk of pathologic progression, particularly grade related, the intensity of their follow-up could be decreased. OBJECTIVE:To i...

    journal_title：European urology

    pub_type： 杂志文章

    doi：10.1016/j.eururo.2013.04.038

    authors： Wong LM,Alibhai SM,Trottier G,Timilshina N,Van der Kwast T,Zlotta A,Lawrentschuk N,Kulkarni G,Hamilton R,Ferrara S,Margel D,Trachtenberg J,Jewett MA,Toi A,Evans A,Fleshner NE,Finelli A

    更新日期：2014-09-01 00:00:00

  • Modified pubovaginal sling and Martius graft for repair of the recurrent vesicovaginal fistula involving the internal urinary sphincter.

    abstract：:A modified Martius graft interposition flap was used in conjunction with the modified pubovaginal sling bladder suspension to treat a recurrent vesicovaginal fistula involving the proximal urethra and bladder neck. The patient recovered with no incontinence, voiding dysfunction or dyspareunia. Incontinence should be a...

    journal_title：European urology

    pub_type： 杂志文章

    doi：10.1159/000475169

    authors： Ghoniem GM,Monga M

    更新日期：1995-01-01 00:00:00

  • Biochemical course after radical retropubic prostatectomy: preliminary results.

    abstract：OBJECTIVE:To investigate prognostic factors in localized and lymphatically spread prostate cancer. METHODS:The biochemical course after radical retropubic prostatectomy in 306 patients was subject to a retrospective analysis. RESULTS:Prostate-specific antigen (PSA), Gleason score (prostatectomy specimen) and patholog...

    journal_title：European urology

    pub_type： 杂志文章

    doi：10.1159/000052479

    authors： Weckermann D,Wawroschek F,Hamm M,Haude K,Harzmann R

    更新日期：2001-04-01 00:00:00

  • EAU Guidelines on Diagnosis and Conservative Management of Urolithiasis.

    abstract：CONTEXT:Low-dose computed tomography (CT) has become the first choice for detection of ureteral calculi. Conservative observational management of renal stones is possible, although the availability of minimally invasive treatment often leads to active treatment. Acute renal colic due to ureteral stone obstruction is an...

    journal_title：European urology

    pub_type： 杂志文章,实务指引,评审

    doi：10.1016/j.eururo.2015.07.040

    authors： Türk C,Petřík A,Sarica K,Seitz C,Skolarikos A,Straub M,Knoll T

    更新日期：2016-03-01 00:00:00