EAU penile cancer guidelines 2009.

Abstract:

CONTEXT:Squamous cell carcinoma (SCC) of the penis is a relatively rare but ominous disease. OBJECTIVE:To present a condensed version of the updated 2009 European Association of Urology (EAU) guidelines on penile SCC. EVIDENCE ACQUISITION:We performed a literature search of new data available up to December 2009. No randomized study was found; consequently, level of evidence (LE) and grade of recommendations (GR) are low. EVIDENCE SYNTHESIS:More insight was gained into the etiology of SCC of the penis, together with improved staging and treatment: Human papillomavirus 16 plays an etiologic role in approximately 40-50% of cases. Similarities in etiology with SCC of the head and neck, the female genitalia, and the anal canal have been found. Improved diagnostics allowed earlier diagnosis, leading to more conservative treatments. Adjuvant and neoadjuvant chemotherapy showed promising results in patients with advanced or recurrent disease. Centralization of the disease contributed to standardization and rapid diffusion of new treatments with improved results and increased organ preservation. CONCLUSIONS:Improvements in the management of SCC of the penis are reflected in changes in the guidelines, but the rarity of the disease precluded randomized studies, leading to low level of evidence and grade of recommendation.

journal_name

Eur Urol

journal_title

European urology

authors

Pizzocaro G,Algaba F,Horenblas S,Solsona E,Tana S,Van Der Poel H,Watkin NA,European Association of Urology (EAU) Guidelines Group on Penile Cancer.

doi

10.1016/j.eururo.2010.01.039

subject

Has Abstract

pub_date

2010-06-01 00:00:00

pages

1002-12

issue

6

eissn

0302-2838

issn

1873-7560

pii

S0302-2838(10)00105-3

journal_volume

57

pub_type

杂志文章,实务指引
  • Echotomographic study in the diagnosis of the nonfunctioning kidney.

    abstract::The results obtained from the nephrosonographic study of 61 functionally inactive kidneys of 57 patients are presented. Its usefulness as a diagnostic tool in the evaluation of hydronephrosis, renal agenesis and retroperitoneal collections is stressed. ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000474011

    authors: Martínez-Piñeiro JA,García JA,Hidalgo L,de la Peña J

    更新日期:1978-01-01 00:00:00

  • Active surveillance of small renal masses: progression patterns of early stage kidney cancer.

    abstract:BACKGROUND:Most early stage kidney cancers are renal cell carcinomas (RCCs), and most are diagnosed incidentally by imaging as small renal masses (SRMs). Indirect evidence suggests that most small RCCs grow slowly and rarely metastasize. OBJECTIVE:To determine the progression and growth rates for newly diagnosed SRMs ...

    journal_title:European urology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.eururo.2011.03.030

    authors: Jewett MA,Mattar K,Basiuk J,Morash CG,Pautler SE,Siemens DR,Tanguay S,Rendon RA,Gleave ME,Drachenberg DE,Chow R,Chung H,Chin JL,Fleshner NE,Evans AJ,Gallie BL,Haider MA,Kachura JR,Kurban G,Fernandes K,Finelli A

    更新日期:2011-07-01 00:00:00

  • A Specific Mapping Study Using Fluorescence Sentinel Lymph Node Detection in Patients with Intermediate- and High-risk Prostate Cancer Undergoing Extended Pelvic Lymph Node Dissection.

    abstract::Sentinel lymph node (SLN) detection techniques have the potential to change the standard of surgical care for patients with prostate cancer. We performed a lymphatic mapping study and determined the value of fluorescence SLN detection with indocyanine green (ICG) for the detection of lymph node metastases in intermedi...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2016.01.034

    authors: Nguyen DP,Huber PM,Metzger TA,Genitsch V,Schudel HH,Thalmann GN

    更新日期:2016-11-01 00:00:00

  • Atezolizumab in Platinum-treated Locally Advanced or Metastatic Urothelial Carcinoma: Outcomes by Prior Number of Regimens.

    abstract:BACKGROUND:Patients with metastatic urothelial carcinoma (mUC) who progress after platinum-based chemotherapy have had few treatment options and uniformly poor outcomes. Atezolizumab (anti-programmed death-ligand 1) was approved in the USA for cisplatin-ineligible and platinum-treated mUC based on IMvigor210, a phase 2...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2017.11.023

    authors: Perez-Gracia JL,Loriot Y,Rosenberg JE,Powles T,Necchi A,Hussain SA,Morales-Barrera R,Retz MM,Niegisch G,Durán I,Théodore C,Grande E,Shen X,Wang J,Nelson B,Derleth CL,van der Heijden MS

    更新日期:2018-03-01 00:00:00

  • Improved suprapubic vesical drainage in transvesical prostatectomy.

    abstract::An improved drainage is used in transvesical prostatectomy in order to avoid urinary retention after removal of the Novak-type suprapubic drainage with bladder neck cerclage haemostasis (described by some authors in 1975). The causes of urinary retention are analysed, the drainage technique as well as the mechanisms e...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000473958

    authors: Nicolescu D,Ioanid P,Galesanu M,Boja R,Neagu V

    更新日期:1978-01-01 00:00:00

  • Methotrexate, vinblastine, adriamycin and cisplatin versus methotrexate and cisplatin in advanced urothelial cancer. A randomized study.

    abstract::From September 1984 to December 1988, 28 consecutive patients with metastatic urothelial cancer entered a randomized study to compare 4 courses of modified methotrexate, vinblastine, adriamycin and cisplatin (M-VAC) to 4 courses of methotrexate followed by folinic acid rescue and cisplatin (MP). Non-responders or rela...

    journal_title:European urology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000471672

    authors: Pizzocaro G,Milani A,Piva L,Faustini M,Spino E

    更新日期:1991-01-01 00:00:00

  • What are the Benefits and Harms of Ureteroscopy Compared with Shock-wave Lithotripsy in the Treatment of Upper Ureteral Stones? A Systematic Review.

    abstract:CONTEXT:Extracorporeal shock wave lithotripsy (SWL) and ureteroscopy (URS), with or without intracorporeal lithotripsy, are the most common treatments for upper ureteric stones. With advances in technology, it is unclear which treatment is most effective and/or safest. OBJECTIVE:To systematically review literature rep...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:10.1016/j.eururo.2017.04.016

    authors: Drake T,Grivas N,Dabestani S,Knoll T,Lam T,Maclennan S,Petrik A,Skolarikos A,Straub M,Tuerk C,Yuan CY,Sarica K

    更新日期:2017-11-01 00:00:00

  • Postpubertal cryptorchism. Morphofunctional study with special reference to Leydig's cells.

    abstract::In a group of 17 patients of postpubertal age with unilateral (n = 15) or bilateral (n = 2) cryptorchism, a significant decrease in the tubular diameter was observed, in addition to Leydig cell hyperplasia (many with cytoplasm vacuolization and/or atrophy) in both the cryptorchid testes and in the contralateral scrota...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000471635

    authors: Sirvent JJ,Bernat R,Rodriguez Tolra J,Navarro MA,Garcia B,Brunet J

    更新日期:1989-01-01 00:00:00

  • Morphologic characterization of preoperatively treated prostate cancer: toward a post-therapy histologic classification.

    abstract:BACKGROUND:Preoperative treatment of prostate cancer (PCa) changes morphology of residual tumors so that the Gleason score is no longer valid. OBJECTIVE:To codify morphologic features of preoperatively treated PCa and identify potential classifiers predictive of outcome. DESIGN, SETTING, AND PARTICIPANTS:We performed...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2009.10.020

    authors: Efstathiou E,Abrahams NA,Tibbs RF,Wang X,Pettaway CA,Pisters LL,Mathew PF,Do KA,Logothetis CJ,Troncoso P

    更新日期:2010-06-01 00:00:00

  • Tissue adhesives: their use in urology.

    abstract::Tissue adhesives have certain advantages and should be used only for nephropexy and urethropexy but not for orchiopexy. Because of possible incrustation it should be avoided in the urinary collecting system. ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000471999

    authors: Kelâmi A

    更新日期:1976-01-01 00:00:00

  • Activation of the thromboxane A2 pathway in human prostate cancer correlates with tumor Gleason score and pathologic stage.

    abstract:OBJECTIVE:We investigated the potential involvement of the thromboxane A(2) (TXA(2)) pathway in human prostate cancer (PCa). METHODS:Expression of cyclooxygenase-2 (COX-2), TXA(2) synthase (TXS), and TXA(2) receptors (TPRs), the main actors of the TXA(2) pathway, was analyzed on serial tissue sections from 46 human PC...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2006.01.036

    authors: Dassesse T,de Leval X,de Leval L,Pirotte B,Castronovo V,Waltregny D

    更新日期:2006-11-01 00:00:00

  • The application of artificial intelligence to microarray data: identification of a novel gene signature to identify bladder cancer progression.

    abstract:BACKGROUND:New methods for identifying bladder cancer (BCa) progression are required. Gene expression microarrays can reveal insights into disease biology and identify novel biomarkers. However, these experiments produce large datasets that are difficult to interpret. OBJECTIVE:To develop a novel method of microarray ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2009.10.029

    authors: Catto JW,Abbod MF,Wild PJ,Linkens DA,Pilarsky C,Rehman I,Rosario DJ,Denzinger S,Burger M,Stoehr R,Knuechel R,Hartmann A,Hamdy FC

    更新日期:2010-03-01 00:00:00

  • The impact of urinary extravasation after radical retropubic prostatectomy on urinary incontinence and anastomotic strictures.

    abstract:OBJECTIVE:The aim of this study was to determine the relevance of urinary extravasation as proven by cystogram 18 days after radical retropubic prostatectomy for the degree of postoperative urinary incontinence and the incidence of anastomotic strictures. PATIENTS AND METHODS:A total of 225 patients underwent radical ...

    journal_title:European urology

    pub_type: 临床试验,杂志文章

    doi:10.1159/000067995

    authors: Schatzl G,Madersbacher S,Hofbauer J,Pycha A,Reiter WJ,Svolba G,Marberger M

    更新日期:1999-09-01 00:00:00

  • Localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity.

    abstract:BACKGROUND:Anandamide, a proposed endogenous cannabinoid (CB) agonist, has been shown to enhance neurogenic responses in vitro of the rat corpus cavernosal tissue (CC). However, no information is available on the distribution of CB-receptors or effects by anandamide in CC from primates or humans. OBJECTIVE:To characte...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2008.12.024

    authors: Gratzke C,Christ GJ,Stief CG,Andersson KE,Hedlund P

    更新日期:2010-02-01 00:00:00

  • Follow-up in prostate cancer patients: which parameters are necessary?

    abstract:AIM:In a retrospective study we examined whether follow-up of prostate cancer (PC) patients can be managed by using prostate-specific antigen (PSA) as a unique tool as postulated recently. PATIENTS AND METHODS:According to strict criteria established in the eighties, at our institution PC patients were monitored by PS...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000019814

    authors: Strohmaier WL,Keller T,Bichler KH

    更新日期:1999-01-01 00:00:00

  • Urinary retention due to catheter occlusion by worms.

    abstract::Herein we report a very rare case involving acute occlusion of a Foley catheter by worms. The treatment consisted of removal of the occluded catheter followed by bladder washing with a Betadine solution mixed with normal saline and introduction of a new catheter. ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000471598

    authors: Ginesin Y,Vardi Y,Levin DR

    更新日期:1989-01-01 00:00:00

  • Duloxetine, a serotonin and noradrenaline reuptake inhibitor (SNRI) for the treatment of stress urinary incontinence: a systematic review.

    abstract:OBJECTIVE:Surgery and pelvic floor muscle training are established methods for treating stress urinary incontinence (SUI). A new serotonin and noradrenaline reuptake inhibitor, duloxetine, has been studied in multiple phase 3 trials as a form of medical management of this condition. This systematic review determined th...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:10.1016/j.eururo.2006.08.041

    authors: Mariappan P,Alhasso A,Ballantyne Z,Grant A,N'Dow J

    更新日期:2007-01-01 00:00:00

  • Myelolipoma of the adrenal gland.

    abstract::Adrenal myelolipoma is a rare benign tumor that is usually asymptomatic. This case is believed to be the 13th surgically removed, attesting to the rarity of this tumor. ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000473191

    authors: Hanafy HM

    更新日期:1981-01-01 00:00:00

  • Tamoxifen as prophylaxis for prevention of gynaecomastia and breast pain associated with bicalutamide 150 mg monotherapy in patients with prostate cancer: a randomised, placebo-controlled, dose-response study.

    abstract:OBJECTIVE:To define the optimum tamoxifen dose for reducing bicalutamide (CASODEX) 150 mg monotherapy-induced breast events (ie, gynaecomastia or breast pain or both) without compromising disease control. METHODS:This was a double-blind, parallel-group, multicentre trial in which 282 patients with prostate cancer were...

    journal_title:European urology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.eururo.2007.01.031

    authors: Fradet Y,Egerdie B,Andersen M,Tammela TL,Nachabe M,Armstrong J,Morris T,Navani S

    更新日期:2007-07-01 00:00:00

  • Ultrasound-guided biopsy of homogenous solid renal masses.

    abstract:OBJECTIVES:We evaluated the reliability of sonographic criteria in selecting solid renal masses for percutaneous fine-needle biopsy. METHODS:In study 1 (intraoperative ultrasound study), we prospectively examined 100 consecutive patients scheduled for partial/radical nephrectomy by using two different high-resolution ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2007.01.078

    authors: Reichelt O,Gajda M,Chyhrai A,Wunderlich H,Junker K,Schubert J

    更新日期:2007-11-01 00:00:00

  • Nephrostomy tube or 'JJ' ureteric stent in ureteric obstruction: assessment of patient perspectives using quality-of-life survey and utility analysis.

    abstract:INTRODUCTION:Upper urinary tract obstruction is often relieved by either a percutaneous nephrostomy tube (PCN) or a ureteric stent. Both can cause considerable morbidity and reduce patient's health-related quality of life (QoL). We have compared the QoL in these 2 groups. PATIENTS AND METHODS:34 patients (21 stent and...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000052529

    authors: Joshi HB,Adams S,Obadeyi OO,Rao PN

    更新日期:2001-06-01 00:00:00

  • Urological evaluation of Behçet patients and the effect of colchicine on fertility.

    abstract::Behçet's disease is a multisystem disorder in which urogenital involvement mainly consists of genital aphthous ulcers, epididymitis, urethritis and recurrent cystitis. Colchicine is commonly used in these patients for the prevention of arthritic episodes. In this prospective study, 62 male patients under colchicine th...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000475121

    authors: Sarica K,Süzer O,Gürler A,Baltaci S,Ozdiler E,Dinçel C

    更新日期:1995-01-01 00:00:00

  • Serum levels of the carboxy-terminal propeptide of type I procollagen and the pyridinoline cross-linked carboxy-terminal telopeptide of type I collagen as markers of bone metastases in patients with prostate carcinoma.

    abstract:OBJECTIVES:To evaluate serum levels of the carboxy-terminal propeptide of type I procollagen (PICP) and the pyridinoline cross-linked carboxy-terminal telopeptide of type I collagen (ICTP) as possible markers of bone metastases in patients with prostate carcinoma (PCA) patients. METHODS:Levels of PICP and ICTP were me...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000474454

    authors: Hosoya Y,Arai K,Honda M,Sumi S,Yoshida K

    更新日期:1997-01-01 00:00:00

  • Retrocaval ureter.

    abstract::3 cases of retrocaval ureter (one of them presenting multiple urological anomalies) are discussed. In the presence of hydronephrosis, early operative reposition of the ureter is essential. Provided that the condition is diagnosed before extreme renal deterioration, the surgical repair can salvage remaining renal funct...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000473971

    authors: Eidelman A,Yuval E,Simon D,Sibi Y

    更新日期:1978-01-01 00:00:00

  • Lethal Prostate Cancer in the PLCO Cancer Screening Trial.

    abstract::The Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial randomized men to usual care or annual prostate-specific antigen (PSA) screening for 6 yr and digital rectal examination for 4 yr. This trial found no difference between the intervention and usual care arms of the study in the primary end point ...

    journal_title:European urology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.eururo.2016.01.009

    authors: Shoag J,Mittal S,Halpern JA,Scherr D,Hu JC,Barbieri CE

    更新日期:2016-07-01 00:00:00

  • Active surveillance for prostate cancers detected in three subsequent rounds of a screening trial: characteristics, PSA doubling times, and outcome.

    abstract:OBJECTIVES:To study active surveillance as a management option for the important number of prostate cancer patients who would not have been diagnosed in the absence of screening. PATIENTS AND METHODS:We analyzed baseline characteristics and outcome parameters of all men on active surveillance who were screen-detected ...

    journal_title:European urology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.eururo.2006.11.053

    authors: Roemeling S,Roobol MJ,de Vries SH,Wolters T,Gosselaar C,van Leenders GJ,Schröder FH

    更新日期:2007-05-01 00:00:00

  • Superficial bladder cancer: survival and prognostic factors.

    abstract::Two hundred and seventeen consecutive patients with superficial bladder cancer stages Ta-T1 were analyzed for survival and prognostic factors. The overall 5-year survival was 88 +/- 5.3%. Factors that impacted significantly on survival were: grade of anaplasia (GI 92 +/- 5.9% vs. GII 87 +/- 7.5% vs. GIII 68 +/- 20.7%;...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000471697

    authors: Sánchez de la Muela P,Rosell D,Agüera L,De Castro F,Isa W,Robles JE,Zudaire JJ,Berián JM

    更新日期:1991-01-01 00:00:00

  • A negative confirmatory biopsy among men on active surveillance for prostate cancer does not protect them from histologic grade progression.

    abstract:BACKGROUND:Many men (21-52%) are reported to have no cancer on the second, also known as the confirmatory, biopsy (B2) for prostate cancer active surveillance (AS). If these men had a reduced risk of pathologic progression, particularly grade related, the intensity of their follow-up could be decreased. OBJECTIVE:To i...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2013.04.038

    authors: Wong LM,Alibhai SM,Trottier G,Timilshina N,Van der Kwast T,Zlotta A,Lawrentschuk N,Kulkarni G,Hamilton R,Ferrara S,Margel D,Trachtenberg J,Jewett MA,Toi A,Evans A,Fleshner NE,Finelli A

    更新日期:2014-09-01 00:00:00

  • Urothelial histopathology surrounding bladder carcinomas.

    abstract::We studied the histological condition of the urothelium surrounding bladder carcinomas in 65 patients who underwent partial resection of the bladder. These examinations showed that urothelial abnormalities were always present, i.e. a direct transition from tumour to normal urothelium was never observed. The histologic...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000472763

    authors: Brünger R,Schubert GE

    更新日期:1987-01-01 00:00:00

  • A novel model of urinary tract differentiation, tissue regeneration, and disease: reprogramming human prostate and bladder cells into induced pluripotent stem cells.

    abstract:BACKGROUND:Primary culture and animal and cell-line models of prostate and bladder development have limitations in describing human biology, and novel strategies that describe the full spectrum of differentiation from foetal through to ageing tissue are required. Recent advances in biology demonstrate that direct repro...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2013.03.054

    authors: Moad M,Pal D,Hepburn AC,Williamson SC,Wilson L,Lako M,Armstrong L,Hayward SW,Franco OE,Cates JM,Fordham SE,Przyborski S,Carr-Wilkinson J,Robson CN,Heer R

    更新日期:2013-11-01 00:00:00